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Preventing fungal contamination in pharmaceuticals

European Pharmaceutical Review

In a review on fungal-contaminated compounded pharmaceuticals and medical devices, researchers have described how the contamination of these products can be due to breaches in sterile compounding procedures. Ahmed et al.

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The role of outsourcing in antibody drug manufacture

European Pharmaceutical Review

stated that when conventional small-molecule compounds were the norm within the industry, closed innovation was standard practise and pharmaceutical companies did R&D in-house. Until 2010, contract manufacturing arrangements were for contract manufacturing (drug-manufacturing/supply) of antibody drugs. Yoshiura et al.

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Establishing quality assurance in personalised preparations

European Pharmaceutical Review

A paper published in Pharmaceutics has proposed how a personalised preparation quality assurance programme can achieve this when these products are developed in compounding laboratories. It requests that compounding laboratories adhering to the programme send samples of it. PACMI selects a drug on a quarterly basis.

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Ethnopharmacology: traditional medicine and modern drug discovery

Pharmaceutical Technology

For example, a widely referenced study from 2012 reported that up to 50% of approved drugs between 1981 and 2010 were directly or indirectly from natural products, while according to the WHO, 11% of drugs considered basic or essential originated from flowering plants.

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The lingering menace of diethylene glycol / ethylene glycol adulteration

European Pharmaceutical Review

2 The issue arose because sulfanilamide is an extremely bitter tasting drug and to taste-mask the elixir formulation for use in children, the compounding pharmacist used EG as it was a good solvent, sweet-tasting and cheap. 5 Both compounds are limited to ≤0.1 USP-NF Propylene Glycol Monograph: USP43-NF38, 2010, 3753.

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7 potential benefits of dandelion root

The Checkup by Singlecare

Dandelion root is often lauded for its anti-inflammatory properties, as well as its antimicrobial effect, due to the presence of a compound called taraxasterol. One of the antioxidants present in dandelion root is beta-carotene, which protects against oxidative stress, as well as polyphenols. It may prevent or reduce inflammation.

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NICE rejects Orchard’s gene therapy for rare childhood disease MLD

pharmaphorum

MLD is an inherited neurodegenerative disorder caused by a deficiency in the ARSA gene coding for the enzyme arylsulfatase-A, which allows sulphatide compounds to build up in the body. Orchard has already offered a confidential discount on the therapy.