July, 2024

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Health Care Providers Increasingly Believe Pharmacists Should Take on More Primary Care Duties

Drug Topics

A survey conducted by Surescripts, a health care solutions company, explored the attitudes of pharmacists and prescribers towards ongoing issues and challenges currently facing the industry.

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FTC Intends to Sue Biggest Pharmacy Benefit Managers for Unfair Negotiating Tactics

Pharmacy Times

In a follow-up to the interim FTC report documenting the business practices of PBMs and the power they hold in the pharmaceutical industry, the Commission now seeks to sue the 3 largest PBMs in the country for driving up the price of insulin and other essential drugs.

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STAT+: How UnitedHealth harnesses its physician empire to squeeze profits out of patients

STAT

UnitedHealth Group started out as a small, Minnesota health insurance company and has since morphed into a modern-day Standard Oil, exerting unmatched dominance over health care in the United States. It’s no secret that UnitedHealth is a colossus: It’s the country’s largest health insurer and the fourth-largest company of any type by revenue, just behind Apple.

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Amgen, BMS and Merck have the most exposure as Big Pharma eyes $183B patent cliff: analyst

Fierce Pharma

While patent cliffs are looming for many of biopharma’s top-selling products, the industry has enormous capacity to respond as “conditions for M&A are favorable,” according to a research note f | While patent cliffs loom for many of biopharma’s top-selling products, the industry has enormous capacity to respond as “conditions for M&A are favorable,” according to a July 11 research note from Morgan Stanley.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Humana inks multi-year partnership with Google to invest deeper in cloud, gen AI technologies

Fierce Healthcare

Humana inked a new multi-year agreement with Google Cloud to modernize its cloud infrastructure and build out generative AI solutions. | Humana inked a new multi-year agreement with Google Cloud to modernize its cloud infrastructure and build out generative AI solutions.

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EMA Accepts GSK Application for Blenrep Combinations in Multiple Myeloma Treatment

BioPharm

GSK’s submission is supported by Phase III trials showing significant progression-free survival benefit and positive overall survival trends using Blenrep combinations compared to standard care.

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Analysis Findings Indicate Relationship Between Maternal Asthma and Risk for Autism Spectrum Disorders

Pharmacy Times

Studies show an increased prevalence of autism spectrum disorder in children of mothers; mouse models have shown links between maternal asthma and altered behavior and brain function.

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Opinion: An aging geriatrician wonders: Who will care for me?

STAT

In 1988, I became one of the first U.S. physicians certified in the new specialty of geriatric medicine, which focuses on the health care of older adults. As an idealistic and optimistic 32-year-old geriatrician, I believed that this branch of medicine would undoubtedly emerge as a vibrant field of medicine, benefiting patients and society. I was also confident that when I reached older adulthood, the health care system would be ready to care for me.

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Lilly's Mounjao triggers more weight loss than Novo Nordisk's Ozempic: study

Fierce Pharma

Is Eli Lilly’s Mounjaro or Novo Nordisk’s Ozempic more effective in helping patients lose weight? | Is Eli Lilly’s Mounjaro or Novo Nordisk’s Ozempic more effective in helping patients lose weight? While a head-to-head trial pitting the two treatments remains ongoing, new evidence shows that Lilly’s tirzepatide may be the superior weight loss product.

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Global IT outage takes down health system EHRs, forces hospitals to cancel non-emergency services

Fierce Healthcare

A widespread outage to Microsoft systems has impacted health systems, hospitals and clinics as electronic health record software has been knocked offline, forcing providers to cancel non-emergency | A widespread outage to Microsoft systems has impacted health systems, hospitals and clinics as electronic health record software has been knocked offline, forcing providers to cancel non-emergency procedures and services.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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Agilent builds its CDMO arm with $925m Biovectra buy

pharmaphorum

Agilent has boosted its contract development and manufacturing organisation (CDMO) capacity with a $925 million deal to buy Biovectra, a Canadian provider of fill-and-finish services and active pharmaceutical ingredients (APIs).It's a statement of intent from Agilent, whose primary business is lab instrumentation and equipment, suggesting that it intends to grow the outsourcing side of its business, which is currently focused on the production of oligonucleotide and peptide medicines.

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Slideshow: Managing The Peak of Asthma Season

Drug Topics

The American College of Allergy, Asthma, and Immunology (ACAAI) recently released its 5 tips to help children and their parents stay educated on asthma peak month.

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FTC Report Acknowledges Impact Pharmacy Benefit Managers Have on Cost, Accessibility of Prescription Drugs

Pharmacy Times

In a new report, the FTC says pharmacy benefit managers act as middlemen in the pharmaceutical industry, leading to the squeezing of independent pharmacies and increases in prices for patients.

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STAT+: Jeff Shuren, medical devices head at FDA, to leave the agency

STAT

Jeffrey Shuren, longtime chief regulator of medical devices at the Food and Drug Administration, announced to staff on Tuesday that he is leaving the agency, according to six sources and an email reviewed by STAT. Shuren, who spent 28 years at the agency, started his FDA career in the Commissioner’s Office in 1998. He became director of the Center for Devices and Radiological Health in 2009 and has served in that position ever since.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Sinking prices for generic meds a major factor in US shortage crisis: report

Fierce Pharma

As lawmakers and industry groups seek to get a handle on U.S. | As lawmakers and industry groups seek to get a handle on U.S. drug shortages, a new white paper from German market analytics firm QYOBO supports the thesis that disproportionately low prices for generic medicines can make it difficult for drugmakers to keep supplies afloat.

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Digital health funding hit $5.7B through June, on track to surpass 2019 and 2023, Rock Health reports

Fierce Healthcare

U.S. digital health startups pulled in $5.7 billion across 266 deals in the first six months of 2024, marking continued momentum in the sector after a rocky few quarters last year. | U.S. digital health startups pulled in $5.7 billion across 266 deals in the first six months of 2024, marking continued momentum in the sector after a rocky few quarters last year.

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Bill that would cut down ‘patent thickets’ clears Senate

pharmaphorum

The US Senate has come together to pass a bill that aims to prevent pharma companies from filing multiple patents around biologic drugs as a way to delay biosimilar competitors.Lawmakers unanimously passed the Affordable Prescriptions for Patients Act of 2023 (S-150), which is part of a lengthening list of measures being taken by Congress to curb the prices of medicines in the US.

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How NVIDIA grew with the healthcare market instead of pushing into it

Pharmaceutical Technology

As the use of AI soared across healthcare, NVIDIA fit the bill in providing the necessary technology – and its stock tells the same story.

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NASH Affects Millions, But the Future for Treatment Remains Brighter Than Ever

Pharmacy Times

Emerging treatments, collaboration between health care providers, and new policy proposals have led to a positive outlook for the future of nonalcoholic steatohepatitis (NASH) and its treatment.

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Opinion: To get a fair deal on Wegovy, buying Novo Nordisk might not be Medicare’s worst option

STAT

Medicare and Medicaid are facing a familiar quandary: how to provide coverage for new weight loss drugs with price tags that could effectively bankrupt the federal government’s health care budget while simultaneously ensuring continuous coverage for all other health care services used by millions of Americans. The Centers for Medicare and Medicaid Services announced in March 2024 that it would cover Wegovy (semaglutide), a new and expensive weight loss medication, for beneficiaries with c

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FDA proposes cell and gene therapy site tours to help regulators learn from industry

Fierce Pharma

It's no secret that cell and gene therapies have faced manufacturing hurdles as the advanced medicines have become increasingly popular in recent years. | It's no secret that cell and gene therapies have faced manufacturing hurdles as the advanced medicines have become increasingly popular in recent years. Now, the FDA is proposing to work directly with industry through a series of facility tours that could enable both sides to learn something from each other.

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Atropos compares how well leading LLMs generate clinical evidence

Fierce Healthcare

A new study released by healthcare AI company Atropos found that general purpose LLMs like ChatGPT, Claude and Gemini are not fit for use in clinical decisionmaking. | Healthcare AI company Atropos conducted a study to test how reliably ChatGPT, Claude, Gemini, OpenEvidence and its own model, ChatRWD, answer clinicians' questions. General use LLMs did not fare well.

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PBMs under the cosh at House hearing on drug pricing

pharmaphorum

The top three pharmacy benefit managers in the US felt the heat at a hearing of the House Oversight Committee, as lawmakers grilled executives over their business practices and accused them of monopolising the supply chain.

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Study suggests targeting amyloid beta production could be promising in AD

Pharma Times

The neurodegenerative disease is currently the most common cause of dementia

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DEA Proposed Rule Seeks to Reclassify Marijuana

Pharmacy Times

Pharmacists could play a major role in answering patient questions and providing counseling about cannabis

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STAT+: Express Scripts overcharged postal workers by $45 million, audit says

STAT

Express Scripts, one of the largest pharmacy benefit managers in the country, overcharged U.S. Postal Service employees by a whopping $45 million for their prescription drugs during a recent five-year period, according to a federal audit. The findings are likely to intensify scrutiny of the controversial role played by PBMs in the opaque pharmaceutical pricing system.

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Game on: Lilly's Alzheimer's drug Kisunla, a challenger to Biogen and Eisai's Leqembi, gains full FDA nod

Fierce Pharma

After turning down Eli Lilly’s Alzheimer’s disease drug donanemab for an accelerated approval last year, the agency has now offered the anti-amyloid therapy—and a competitor to Eisai and Bioge | After turning down Eli Lilly’s Alzheimer’s disease drug donanemab for an accelerated approval last year, the agency has now offered the anti-amyloid therapy, a competitor to Eisai and Biogen’s Leqembi, a full approval.

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Optum lays off more employees at Landmark, OptumInsight

Fierce Healthcare

The sprawling enterprise that is UnitedHealth Group is undergoing more layoffs under its Optum umbrella. | UnitedHealth's Optum is again laying off workers, with the scope unconfirmed. Landmark Health is downsizing once again and leaving major metropolitan areas.

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Ipsen builds again, licensing Day One glioma drug

pharmaphorum

Ipsen has signed yet another portfolio-expanding deal – its fifth of the year so far – claiming rights outside the US to a drug for common brain cancer glioma from Day One Biopharmaceuticals.

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STAT+: A pricey Gilead HIV drug could be made for dramatically less than the company claims, researchers say

STAT

Following the release of widely touted study results for a Gilead Sciences HIV treatment, a new analysis finds the medicine — called lenacapavir — could be made for as little as $26 to $40 per person each year, which the researchers argue could alleviate concerns about limited access in many countries. The medicine drew considerable attention last month after a late-stage clinical trial found that twice-a-year injections completely protected cisgender women from contracting HIV.

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Bird flu that infected 6 Colorado poultry workers is closely related to the virus in cows

STAT

Bird flu snapshot: This is the latest installment in a series of regular updates on H5N1 avian flu that STAT is publishing on Monday mornings. To read future updates, you can also subscribe to STAT’s Morning Rounds newsletter. Public health experts who’ve been following the surprising spillover of H5N1 bird flu into America’s dairy cattle herds now have all eyes on Colorado, waiting to see if a cluster of human cases there might balloon into something bigger.

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STAT+: Jiankui He, creator of CRISPR-edited children, relocates to a Chinese medical tourism hub

STAT

Jiankui He, the Chinese scientist who s parked a global uproar in 2018 when he revealed he had created the first gene-edited children , is again out on his own after being dismissed from an academic post. In January 2019, provincial health authorities found that He’s human CRISPR experiments violated national regulations against gene-editing for reproductive purposes.

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Kamala Harris, endorsed by Biden to replace him, is left of the president on health care

STAT

WASHINGTON — President Biden is ending his bid for a second term in office and backing Vice President Kamala Harris to take the nomination, he announced Sunday. While Harris shares similar views as Biden on many issues, she is to the left of the president on health care. “I believe it is in the best interest of my party and the country for me to stand down and focus solely on fulfilling my duties as president for the remainder of my term,” the president wrote in a letter sha

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Q&A: Trans adults face ‘shocking’ risk of cirrhosis, especially alcohol-driven

STAT

People under 45 have been driving an increase in liver-related deaths, especially those caused by alcohol. But a sliver of that young adult population is being hit disproportionately hard by alcohol-associated liver disease: transgender people. Although trans adults make up less than 1% of the United States population, a study published in The American Journal of Gastroenterology last month shows they face double the risk of severe liver disease, and a higher share of cirrhosis from heavy drinki

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