Trending Articles

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Phase 3 Trial to Evaluate Molnupiravir for Treatment of COVID-19 in High-Risk Adults

Drug Topics

The MOVe-NOW study will assess the investigational oral antiviral using a different formulation than what is currently approved under an emergency use authorization.

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STAT+: Inside a Nobel-winning marriage: They see each other as scientific equals, even if the prize committee doesn’t

STAT

One day in early August in 2001, Victor Ambros received an email from an editor at Science, asking him to review two new studies the journal was considering publishing. Ten years earlier, Ambros and his wife and lab manager, Rosalind Lee, had discovered a strange new sort of molecule — a tiny bit of free-floating genetic code that came to be known as microRNA — inside the millimeter-long bodies of C. elegans roundworms.

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Cannabis Could Help Reduce Opioid Use in Patients with Chronic Pain

Drug Topics

Most patients with reduced opioid prescriptions during cannabis use had chronic musculoskeletal pain.

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Analysis Finds Low-Income Countries Face More Cancer-Related Deaths and Inequities in Therapy Access

Pharmacy Times

Potential solutions can include international funding, improved primary health care measures, and cost-effective screening methods.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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RFK Jr. could 'cost lives in this country' if he pursues changes to US vaccine policy, Gottlieb says

Fierce Pharma

Robert F. Kennedy Jr.’s appointment last month to lead the U.S. Department of Health and Human Services immediately sent waves of speculation swirling throughout the biopharma industry. | The former FDA Commissioner pointed to the threat of measles if vaccination rates were to decline by 5%.

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UnitedHealthcare CEO Brian Thompson fatally shot in Manhattan: reports

Fierce Healthcare

UnitedHealth Group abruptly ended its investor day event on Wednesday morning as new reports surfaced that the CEO of its health plan division had been fatally shot. | UnitedHealth Group abruptly ended its investor day event on Wednesday morning as news reports surfaced that the CEO of its health plan division had been fatally shot.

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Genmab expands its pipeline with $630m Scancell deal

pharmaphorum

Genmab has licensed another anti-glycan antibody for cancer from UK biotech Scancell as it continues to expand its in-house pipeline.

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Bird flu theories, the worst-rated restaurants, and not your grandfather’s radiation therapy

STAT

Get your daily dose of health and medicine every weekday with STAT’s free newsletter Morning Rounds.  Sign up here. Good morning! I hope you had a lovely holiday weekend and feel rested and ready for the last sprint of 2024.

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Legislators urge DOJ to investigate PBMs for potential role in opioid epidemic

Fierce Healthcare

A group of legislators is calling on the Department of Justice to dig into whether pharmacy benefit managers played a role in the opioid epidemic. | A group of legislators is calling on the Department of Justice to dig into whether pharmacy benefit managers played a role in the opioid epidemic.

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Younger, Middle-Aged Adults Face Higher Burden of Neurologic Long COVID Symptoms

Drug Topics

The higher burden of neurological symptoms among younger and middle-aged adults translated to worse subjective quality of life, according to a recent study.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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FDA Approves Ustekinumab-kfce as Biosimilar to Ustekinumab

Pharmacy Times

The biosimilar is approved for the treatment of Crohn disease, ulcerative colitis, plaque psoriasis, and psoriatic arthritis.

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Deadline looms for post-Brexit label changes for UK meds

pharmaphorum

The MHRA has reminded pharma companies that from 1st January all medicines sold in the UK will have to comply with new labelling requirements

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Why is health care cybersecurity so bad?

STAT

Year after year, more Americans are affected by health care data breaches. Though health savings accounts, pharmacies, and major hospitals have all been attacked in 2024, a single data breach accounted for the vast majority of people’s data being exposed: Change Healthcare. Multiple times this year, lawmakers have questioned health care industry experts about why the massive and disruptive Change Healthcare breach was allowed to happen , and what the government should do to improve health

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M&A or affiliation improved rural hospitals' margins, reduced risk of closure: report

Fierce Healthcare

Nearly half of rural hospitals moved out of the high-risk category after a merger, acquisition or affiliation with a larger system, a new analysis has found. | The analysis, conducted by healthcare consulting firm Dobson DaVanzo, found that among 110 rural hospitals that closed between 2011 and 2021, more than half were standalone hospitals without support from larger systems.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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A Look Back at the Affordable Care Act

Drug Topics

The Affordable Care Act was passed in 2010 to make health care and prescription medicine more accessible. Did it succeed?

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FDA Grants Orphan Drug Designation to Novel Gene Therapy for Fabry Disease

Pharmacy Times

Fabry disease is a rare lysosomal disorder that causes excessive deposition of lipids in tissues.

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With AstraZeneca exec under investigation in China, company names Reic new international chief

Fierce Pharma

With AstraZeneca’s former international chief, Leon Wang, under investigation in China, the company has promoted an AZ veteran to fill the post. | With AstraZeneca’s former international chief, Leon Wang, under investigation in China, the company has promoted an AZ veteran to fill the post. The British giant has appointed Iskra Reic, Ph.D., as its new international executive vice president.

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How automating flow cytometry is revolutionising cancer diagnosis and treatment

pharmaphorum

Discover how the automation of flow cytometry is transforming cancer diagnosis and treatment for breast, prostate, endometrial, pancreatic, kidney, and melanoma cancers. Explore the latest advancements in the field.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Healthcare industry needs to get a grip on AI governance in 2025, ECRI warns

Fierce Healthcare

Risks with AI-enabled health technologies topped the list of the ECRI Institute's annual ranking of health technology hazards. | A well-known safety group debuted its annual report that lays out the top 10 health technology risks for the upcoming year. The risks of AI perpetuating bias or hallucinating answers to medical questions tops the list of risks for 2025.

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Influenza Vaccine Least Effective for Children Facing Secondary Infection

Drug Topics

Researchers addressed vaccine effectiveness for individuals with direct household contacts that reported influenza.

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Zenocutuzumab-zbco Granted Accelerated Approval for Patients With NSCLC, Pancreatic Ductal Adenocarcinoma

Pharmacy Times

Zenocutuzumab-zbco is a bispecific antibody that targets and binds to HER2 and HER3.

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STAT+: Generative AI is transforming radiology, and it’s only the beginning

STAT

By 2030, agreed a roomful of radiologists in Chicago this week, generative AI will be ubiquitous in their written work.  Medical imaging already leads the way in the clinical application of artificial intelligence: Algorithms that help to analyze CT scans, MRIs, and X-rays account for more than three-quarters of AI-based devices authorized by the Food and Drug Administration.

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UK government commits to first men's health strategy

pharmaphorum

UK government commits to first men's health strategy Phil.

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CMS names two drug manufacturers for cell and gene therapy model

Fierce Healthcare

The Centers for Medicare & Medicaid Services has successfully negotiated agreements with two drug manufacturers to participate in the newly created Cell and Gene Therapy Access Model. | The two drugs treat sickle cell disease, the stated first priority of the new CMS model set to begin in January.

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Impact of the Inflation Reduction Act on Biosimilar Pricing, Dispensing

Drug Topics

On the most recent episode of Over the Counter, Steve Callahan, Senior Director of Advisory & Insights at MMIT, talked with us about biosimilars and the Inflation Reduction Act.

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Familiarize Yourself With Updated Clinical Guidelines Recommendations for Restless Legs Syndrome

Pharmacy Times

Treatment for RLS includes lifestyle modifications, medication, and in some cases, non-drug therapies, aiming to reduce symptoms and improve sleep and daytime functioning.

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‘Leptin’s last chance’: Mouse study says infamous weight loss drug failure could boost GLP-1s

STAT

The hormone leptin was discovered 30 years ago to much fanfare. Scientists hoped that leptin, which regulates body fat, could pave the way for obesity treatments. The results in mice were hailed as “miraculous,” and Amgen licensed the hormone for $20 million from Rockefeller University. But its initial promise failed to pan out, as treatments mimicking leptin in the body didn’t spur weight loss.

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Novartis pays $1bn upfront for Huntington's drug from PTC

pharmaphorum

Novartis has made a return to the Huntington's disease stage by licensing an oral mRNA splicer from PTC Therapeutics for $1 billion upfront

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Why Do Women Need Testosterone?

Compounding Pharmacy of America

Learn how Testosterone Replacement Therapy (TRT) can enhance energy, mood, and overall health in women. Discover signs of low testosterone, TRT benefits, and natural hormone support. The post Why Do Women Need Testosterone? appeared first on The Compounding Pharmacy of America.

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It’s Time to Staunch Our Self-Inflicted Wounds

Drug Topics

Outside forces are at play, but pharmacists must turn inward to address some challenges in their profession.

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Navitoclax and Ruxolitinib Show Potential in Treating R/R Myelofibrosis

Pharmacy Times

The addition of navitoclax was associated with durable response and potential disease modification.

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STAT+: Why Orexo is abandoning a digital therapeutic for depression

STAT

Swedish pharmaceutical company Orexo will no longer pursue an app for treating depression after many years of struggling to sell it. Orexo announced this week that it will no longer license the product, called Deprexis, from German manufacturer GAIA. The companies have worked together on Deprexis in the United States since 2020 and have deals for two other apps, including Modia, an app that provides psychosocial support to people being treated for opioid addiction.

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Adcendo raises $135m for cancer ADCs, and other financings

pharmaphorum

Adcendo raises $135m for cancer ADCs, plus financings for Enveda, Cradle Bio, ATB Therapeutics, and 35Pharma

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