article thumbnail

STAT+: Drug may make chemotherapies less effective in cancer patients with obesity — but many doctors are in the dark

STAT

This means chemotherapies may be less effective when interacting with the medicine, but some clinicians, and their patients, are unaware of that possibility. A drug used to combat fungal infections in cancer patients comes with a big caveat — research shows the medicine can last twice as long as in people with obesity.

article thumbnail

ASCO 2025: Informing Treatment Decisions Using a 14-Gene Assay in Early-Stage NSCLC

Pharmacy Times

A study reveals a 14-gene assay guides chemotherapy decisions effectively in patients with early-stage non-small cell lung cancer (NSCLC).

Insiders

Sign Up for our Newsletter

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

article thumbnail

STAT+: Jazz Pharmaceuticals to acquire Chimerix and its experimental brain cancer drug

STAT

It responds poorly to chemotherapy and is usually driven by a mutation that can’t be drugged with traditional approaches. The tumor, known as diffuse midline glioma, or DMG (and sometimes as DIPG depending on where it’s found), has flummoxed researchers for decades. Median survival is generally cited as less than a year. 

article thumbnail

Q&A: How IQVIA Keeps Pharmacists Engaged with US Prescription Drug Use

Drug Topics

Often those very high-end medicines are for very few people.

article thumbnail

What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

This new guidance will clearly impact the clinical research field, but how?

article thumbnail

Assessing Prescriber Justification for Use of Outpatient Chemotherapy in the Acute Care Setting

Pharmacy Times

This single-center, descriptive, retrospective chart review identified barriers to outpatient chemotherapy use, revealing avoidable inpatient stays and highlighting targets for stewardship interventions.

article thumbnail

Is prescribing anticancer drugs by body surface area still relevant?

Hospital Pharmacy Europe

The approach was adopted widely, particularly for cytotoxic chemotherapy agents, with the aim of standardising drug exposure and minimising toxicity. 5,6 Freireich et als work further validated this approach, showing that BSA correlated with drug efficacy and toxicity across several chemotherapy agents. 6 Gurney H.