pharmaphorum

APRIL 1, 2021

The FDA has approved Sanofi’s Sarclisa (isatuximab) in combination with a new chemotherapy regimen for advanced multiple myeloma, building on a first approval last year. The median progression free survival (PFS) for Sarclisa combination therapy was not reached at the time of the pre-planned interim analysis, the company said.

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Pharmaceutical Technology

JANUARY 12, 2023

It has been approved to treat NSCLC patients with EGFR Exon20 insertion mutations, whose disease has advanced on or after they received platinum-based chemotherapy. Rash, decreased appetite, paronychia, and diarrhoea are the most common adverse reactions (TRAEs) related to the treatment.

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The Checkup by Singlecare

APRIL 14, 2024

Certain supplements, flea medications, and chemotherapy drugs may also cause adverse reactions. Metronidazole also has drug interactions with several other medications, including cyclosporine, phenobarbital, and phenytoin. How much metronidazole can I give my dog?

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Dosage Adverse Reactions Chemotherapy Labelling 98

The Checkup by Singlecare

JANUARY 23, 2024

It is known as an antineoplastic (chemotherapy) agent, a disease-modifying antirheumatic drug ( DMARD ), and an immunosuppressant agent. Methotrexate has distinct mechanisms of action for its use as chemotherapy versus immunosuppression in autoimmune diseases.

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Adverse Reactions Chemotherapy Communication Immunization 52

pharmaphorum

JANUARY 26, 2022

It covers three phase 3 trials involving subjects with myelodysplastic syndrome (MDS) and acute myeloid leukaemia (AML), as well as ‘unfit’ AML patients who are unable to be treated with intensive treatment like high-dose chemotherapy.

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The Checkup by Singlecare

JUNE 20, 2023

If your immune system is compromised due to medication, chemotherapy, or radiation therapy, probiotics may increase the risk of developing a bacterial or fungal infection. People with compromised immune systems. People with a severe illness. Together, you can weigh the benefits and risks carefully. The post Who should not take probiotics?

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The Checkup by Singlecare

OCTOBER 16, 2023

Chemotherapy-Induced Peripheral Neuropathy Studies have shown that duloxetine may help prevent or reduce nerve pain in people who have been treated with chemotherapy. For example, you may have experienced adverse reactions or other health concerns while taking the generic version in the past.

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Pharmaceutical Technology

NOVEMBER 9, 2022

The US Food and Drug Administration (FDA) has approved Regeneron Pharmaceuticals ’ PD-1 inhibitor Libtayo (cemiplimab-rwlc) and chemotherapy combination as the first-line treatment for advanced non-small cell lung cancer (NSCLC). The regulatory approval is based on results obtained from the international Phase III EMPOWER-Lung 3 trial.

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Chemotherapy FDA Adverse Reactions 52

Pharmaceutical Technology

NOVEMBER 23, 2022

Libtayo is also indicated for treating progression of the disease on or following platinum-based chemotherapy. The trial enrolled 608 subjects in 14 countries, regardless of their PD-L1 expression status or histology and assessed Libtayo versus a chemotherapy of investigator's choice.

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Pharmaceutical Technology

FEBRUARY 5, 2023

The FDA approval is based on the data obtained from a global, multicentre, open-label Phase III TROPiCS-02 study conducted in 543 HR+/HER2- metastatic breast cancer patients who have received prior endocrine therapy, CDK4/6 inhibitor and two to four lines of chemotherapy for metastatic disease. Trodelvy showed 3.2

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Pharmaceutical Technology

MARCH 23, 2023

Zynyz monotherapy showed a 52% objective response rate (ORR) in chemotherapy-naïve patients. Diarrhoea, rash, pyrexia, nausea, musculoskeletal pain, fatigue and pruritus are the most common adverse reactions observed in patients treated with Zynyz. Partial response was seen in 22 patients and complete response in 12 patients.

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pharmaphorum

APRIL 14, 2021

Trodelvy (sacituzumab govitecan) has been approved for locally advanced or metastatic urothelial cancer, following a platinum-containing chemotherapy and PD-1/PD-L1 inhibitor immunotherapy. Adverse reactions leading to treatment discontinuation occurred in 10% of those receiving Trodelvy, with 4% discontinuing treatment due to neutropenia.

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Adverse Reactions Chemotherapy FDA 52

European Pharmaceutical Review

NOVEMBER 24, 2022

s Libtayo ® (cemiplimab) for adults with recurrent or metastatic cervical cancer and disease progression while on or after platinum-based chemotherapy. “Libtayo ® was the first programmed cell death protein (PD)-1 inhibitor to demonstrate significant improvements in survival compared to chemotherapy in a Phase III trial.

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Chemotherapy Immunization Adverse Reactions Hospitals 89

Pharmaceutical Technology

MAY 22, 2023

As a non-chemotherapy, single-agent treatment for DLBCL patients, we hope that Epkinly can effectively treat this aggressive cancer type and can be used for patient care quickly and in an off-the-shelf form for physicians. The FDA approval of Epkinly represents a new treatment mechanism of action for third-line DLBCL patients. “As

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FDA Adverse Reactions Chemotherapy Patient Care 52

The Checkup by Singlecare

FEBRUARY 1, 2024

Prednisone is usually used as an add-on treatment to chemotherapy drugs or as a palliative treatment for advanced cancers. Of the lymphatic cancers, lymphoma is common, representing about 15% to 20% of cancers diagnosed in dogs every year. Lymphatic cancer cells have corticosteroid receptors that induce those cells to die.

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The Thyroid Pharmacist

SEPTEMBER 1, 2023

They include anesthetics, antacids, anti-anxiety medications, antibiotics, antidepressants, antifungals, cholesterol-lowering medications, anti-malarial medications, chemotherapy, appetite suppressants, arthritis medications, psychotropics, and steroids. Who is Likely to Have an Adverse Reaction to Fluoride, and What are the Symptoms?

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The Checkup by Singlecare

OCTOBER 27, 2023

By bringing up a potential interaction with amoxicillin-potassium clavulanate, you could avoid an adverse reaction or, at the very least, have peace of mind and a better understanding of why it is being prescribed for you. Taking an active role in your own care is essential for the best outcomes.

Adverse Reactions 52

Adverse Reactions Labelling Chemotherapy Communication 52

European Pharmaceutical Review

DECEMBER 27, 2023

Bridging therapy has been shown to correlate with an inferior response to CAR T-cell therapy due to both progression of the chemotherapy-refractory malignant disease during the manufacturing period and increased toxicity. After this incident CAR-related toxicity scales and guidelines were established to prevent adverse reactions.

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The Thyroid Pharmacist

JULY 8, 2022

It’s important to note that selenium may also interact with other supplements and medications, such as cholesterol-lowering statin drugs, antacids, chemotherapy drugs, corticosteroids, niacin, and even birth control pills. At high enough levels, selenium can cause death (reports of this level of toxicity exist, but are extremely rare). (58,

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