Vaccines to Watch in 2024
Drug Topics
MARCH 19, 2024
Moderna, Merck, and Pfizer-BioNTech are leading the charge with new vaccines for respiratory viruses in development.
Sat.Mar 16, 2024 - Fri.Mar 22, 2024
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Patient centricity for tailor-made healthcare
European Pharmaceutical Review
MARCH 21, 2024
Can you tell us a bit about yourself and your role at Pfizer? I’m a pharmacist with an MBA and PhD. My PhD thesis is about considerations in the production and purchasing of drugs. I joined Pfizer in January 2023 as a health access specialist, after working at Clalit Health Services in Israel for almost 20 years. At Clalit, which is the second largest healthcare provider in the world, I worked in several management positions and gained a broad understanding of the needs and constraints of a heal
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Adaptation Is the Key to Success
Drug Topics
MARCH 21, 2024
Farmers and welders have adapted to work with the current times. Pharmacists should consider adapting their profession as well.
Pharmacist Role in Addressing Operational Challenges of Bispecifics in MM
Pharmacy Times
MARCH 18, 2024
Michael Singel, PharmD, discusses the role of pharmacists in the operationalization of bispecifics to treat multiple myeloma, including the creation of treatment plans and standard of care order sets.
Position Your Pharmacy for Expansion
Speaker: Chris Antypas and Josh Halladay
Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.
3D printing and personalised medicines: embracing innovative technologies
Hospital Pharmacy Europe
MARCH 21, 2024
Supporting the successful compounding of drugs with 3D printing processes has the potential to not only fulfil unmet patient needs but also drive efficiencies in hospital pharmacies. Ian Soulairol from the Institut Charles Gerhardt Montpellier at Montpellier University and pharmacist at the Department of Pharmacy of Nîmes University Hospital in France shares insights into how this technology is evolving and what it means for clinical practice now and in the future. 3D printing, or additive manuf
FDA authorizes new drug to protect immune compromised from Covid-19
STAT
MARCH 22, 2024
The Food and Drug Administration on Friday authorized a new antibody to protect immunocompromised individuals against Covid-19. The drug, known as Pemgarda and marketed by the biotech Invivyd, is the first such drug to become available since the agency pulled AstraZeneca’s Evusheld off the market in January 2023. New Omicron variants had rendered Evusheld ineffective.
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FDA Expands Label for Bempedoic Acid to Reduce Cardiovascular Risk, With or Without Statins
Pharmacy Times
MARCH 22, 2024
Bempedoic acid (Nexletol; Esperion) and bempedoic acid and ezetimibe (Nexlizet; Esperion) are the only LDL-C lowering non-statin drugs indicated for primary prevention patients.
Providers 'wasted' $10.6B in 2022 overturning claims denials, survey finds
Fierce Healthcare
MARCH 21, 2024
More than 100 provider organizations want the Centers for Medicare & Medicaid Services (CMS) to take a tougher stance on Medicare Advantage (MA) plans’ practices following an industry survey es | Providers spent nearly $20 billion in 2022 pursuing delays and denials across all payer types, yet those efforts are substantially more costly on average when dealing with private plans, hundreds of hospitals and health systems told Premier in a recent survey.
STAT+: Gene-edited pig kidney transplanted into a living patient for the first time
STAT
MARCH 21, 2024
In a new test of xenotransplantation, a medical team at Massachusetts General Hospital announced Thursday that, for the first time, it had transplanted a kidney from a CRISPR gene-edited pig into a living patient. Surgeons performed the milestone procedure over four hours on Saturday, March 16, without complications. As of Thursday morning, the organ recipient, a 62-year-old man named Richard Slayman, was “recovering well” and expected to be discharged soon, the hospital said in a
Psilocybin Side Effects Found to be Tolerable, Resolve Within 2 Days
Drug Topics
MARCH 22, 2024
Results from a meta-analysis on the side of effects of the psychedelic psilocybin were presented at the 2024 American Pharmacists Association Annual Meeting & Exposition.
What the FDA's New Dosage Guidance Means for the Future of Clinical Research
Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist
What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.
Study: Researchers Identify 25 Air Pollutants Associated With Asthma Symptoms
Pharmacy Times
MARCH 16, 2024
Investigators found that 1,1,1 trichloroethane; 2-nitropropane; and 2,4,6 trichlorophenol were significantly associated with asthma symptoms for 3 exposure periods.
Google's healthcare AI ambitions: New model for personal health coaching and next steps for gen AI
Fierce Healthcare
MARCH 19, 2024
Google is doubling down on its ambitions for healthcare AI by exploring how generative AI can help clinicians in medical decision-making, understand lab and imaging information and provide con | Google is hyper-focused on generative AI in healthcare, pushing forward research to advance gen AI capabilities that can help clinicians in medical decision-making, understand lab and imaging information and provide consumers with personalized health insights based on their wearable data.
STAT+: New gene therapy, to be priced at $4.25 million, has already transformed children’s lives
STAT
MARCH 20, 2024
Every morning, Victoria Rasberry gets up before 6 a.m., walks to the bedroom down the hall, and helps her 8-year-old daughter Addi slide into a set of contraptions that squeeze and suck out the thick mucus constantly threatening to choke her airways closed. She feeds Addi breakfast through a stomach tube and makes sure she has the right mix of the 28 different medications required to keep her free of pain, infections, and seizures.
Novavax COVID-19 Vaccine Shows Lasting Protection Against Delta Variant
Drug Topics
MARCH 19, 2024
The biotechnology company’s recombinant spike protein-based vaccine demonstrated an efficacy of 88% after 40 days, 82% after 120 days, and 77% after 180 days during the PREVENT-19 trial.
5 Reasons to Upgrade Your Pharmacy Management Software
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Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.
FDA Issues Paper on the Responsible Use of Artificial Intelligence in Medical Research
Pharmacy Times
MARCH 19, 2024
The agency will focus on collaboration to protect public health; advancing regulatory approaches; developing standards, guidelines, and best practices; and supporting research that evaluates and monitors AI performance.
SXSW24: Better communication, collaboration, reimbursement needed to improve cancer care
Fierce Healthcare
MARCH 22, 2024
Uncomfortable waiting rooms. Revealing hospital gowns. Confusing insurance. Exhausting travel between appointments. | Oncology was a major focus at this year’s SXSW conference. Across multiple sessions, clinicians and patient advocates called for better access to specialty care, more thoughtful communication with patients and continued collaboration across stakeholders.
A study says intermittent fasting is making people drop dead. Oh, come on
STAT
MARCH 19, 2024
The news is everywhere in my social news feeds this morning: A popular fad diet is apparently lethal, scientific research says. Specifically, a study found that caloric restriction, also known as intermittent fasting, has a 91% risk of death due to cardiovascular disease. Except scientific research doesn’t say that — and not only should you not be worried about this study, you shouldn’t be wasting brain glucose thinking about it.
Local Pharmacy Access in the United States Significantly Lower in Rural Areas
Drug Topics
MARCH 21, 2024
Researchers collected data to measure inequities in pharmacy access across the country.
As Cannabis Use Increases, Pharmacists Must Be Prepared to Counsel Patients
Pharmacy Times
MARCH 22, 2024
As more states have legalized cannabis use—both medicinal and recreational—Sera said pharmacists’ roles in counseling will become even more important.
BioNTech's shares tumble—again—amid continued COVID vaccine sales slide
Fierce Pharma
MARCH 20, 2024
Four months ago, when BioNTech slashed its 2023 revenue projection from 5 billi | When BioNTech reported its fourth-quarter earnings Wednesday, it was another harsh reminder of the plummeting demand for COVID-19 vaccines. Sales came to 1.5 billion euros ($1.6 billion) for the fourth quarter and 3.8 billion euros ($4.1 billion) for 2023, coming up short of expectations.
Opinion: The evidence is clear: A liquid-only diet before a colonoscopy is unnecessary
STAT
MARCH 19, 2024
Since colorectal cancer is on the rise in people younger than age 50, national guidelines have recently pushed the starting age for colorectal cancer screening down to 45. We need to spread the word. Yet we specialists continue to provide outdated and disproven recommendations on colonoscopy bowel preparation that make the process more difficult for the millions of patients who undergo colonoscopy every year: We tell them to adopt a clear liquid diet the day before their procedure.
FDA Approves Rilpivirine For Treatment of HIV-1 in Pediatric Patients
Drug Topics
MARCH 21, 2024
Rilpivirine (Edurant Ped) effectively suppresses the HIV-1 virus in pediatric patients with HIV-1 RNA less than or equal to 100,000 copies/mL in combination with other antiretroviral therapies.
Navigating Cannabis in Pharmacy Practice: State Legislation and Contraindications for Patient Use
Pharmacy Times
MARCH 22, 2024
Pharmacists can educate patients on current clinical evidence of cannabis’s therapeutic benefit, as well as cannabis’s complexities, risks, and potential adverse effects.
Nvidia inks tie-ups with Abridge, GE HealthCare and Microsoft as it expands its footprint in healthcare AI
Fierce Healthcare
MARCH 21, 2024
Chipmaker Nvidia sees big opportunities in healthcare AI and this week it launched more than two dozen new gen AI-powered microservices. | The global computing powerhouse inked collaborations with Abridge, Microsoft, GE HealthCare and Hippocratic AI to to expand its generative AI capabilities into healthcare and life sciences.
Top U.S. addiction researcher calls GLP-1 data for addiction ‘very, very exciting’
STAT
MARCH 21, 2024
Early data regarding the use of GLP-1 medications like Ozempic and Wegovy to treat addiction is “very, very, exciting,” Nora Volkow, the director of the National Institute on Drug Abuse, said Thursday. But even as she expressed enthusiasm for the new drugs’ potential, Volkow criticized pharmaceutical companies for neglecting a moral imperative to develop new addiction treatments — but acknowledged that the health system more broadly doesn’t incentivize drug com
Veterans Reported Loss of Everyday Functioning After COVID-19 Pandemic
Drug Topics
MARCH 22, 2024
Researchers aimed to address the adverse effects of veterans with COVID-19 diagnoses 18 months after infections were documented.
Celltrion USA Submits Biologics License Application for CT-P39, a Biosimilar to Xolair
Pharmacy Times
MARCH 21, 2024
The BLA includes all indications for Xolair, including asthma, chronic rhinosinusitis with nasal polyps, immunoglobulin E-mediated food allergy, and chronic spontaneous urticaria.
Hippocratic AI banks $53M backed by General Catalyst, a16z, Memorial Hermann, UHS and other health systems
Fierce Healthcare
MARCH 19, 2024
Launched out of stealth about a year ago, Hippocratic AI launched its first generative AI product and pocketed $53 million in series A funding, the startup announced Monday. | Launched out of stealth about a year ago, Hippocratic AI launched its first generative AI product and pocketed $53 million in series A funding. The fresh funding boosts the company's valuation to $500 million.
STAT+: As Humira biosimilars take over the market, CVS has created a new ploy: the drug ‘rebate credit’
STAT
MARCH 18, 2024
The biggest enticement that large pharmacy benefit managers offer to the employers that hire them is drug rebates — a steady stream of money sent back to their clients, a tangible symbol of the discounts that PBMs are able to wrangle out of pharmaceutical companies. PBMs, the middlemen of drug pricing negotiations, also claim portions of those lucrative rebates for themselves.
Novo Nordisk closes in on EU approval for its once-weekly insulin Awiqli
Fierce Pharma
MARCH 22, 2024
Sales are booming for Novo Nordisk’s GLP-1 treatments for diabetes and obesity. But that doesn’t mean the Danish company has moved on from its previous generation of blood sugar modulators. | With a positive recommendation from Europe’s Committee for Medicinal Products for Human Use (CHMP), Novo has come a step closer to bringing its revolutionary Awiqli (once weekly basal insulin icodec) to the market.
FDA Advisory Committee Votes in Favor of Ide-Cel for Adult Patients With Multiple Myeloma
Pharmacy Times
MARCH 18, 2024
The decision to vote in favor of idecabtagene vicleucel comes after positive phase 3 trial results demonstrating its efficacy compared with standard regimens.
Google Health, Stanford Medicine unveil open-access dataset of diverse dermatology images
Fierce Healthcare
MARCH 19, 2024
Google Health unveiled an open-access dataset of real-world dermatology images in partnership with Stanford Medicine. | Thousands of people contributed their images of skin, hair and nail conditions to the Skin Condition Image Network (SCIN) for a diverse dataset reflecting various skin tones, ages, settings and condition severities.
STAT+: Digital tools for diabetes management did not deliver benefits that justify cost, new report finds
STAT
MARCH 21, 2024
The last decade has seen billions of dollars flow into digital health companies that promise to improve outcomes for the 38 million Americans living with type 2 diabetes. Their products aren’t cheap, but in the long term, they pitch to health plans and employers that these digital tools will help cut health care costs by preventing serious complications like amputation and kidney failure.
Orchard sets new gene therapy price tag at $4.25M—the steepest of any drug in the US
Fierce Pharma
MARCH 20, 2024
After scoring an FDA nod Monday for the first gene therapy to treat the rare genetic disease metachromatic leukodystrophy (MLD) in the U.S., Kyowa Kirin and its subsidiary Orchard Therapeutics have | After scoring an FDA nod Monday for the first gene therapy to treat the rare genetic disease metachromatic leukodystrophy in the U.S., Kyowa Kirin and its subsidiary Orchard Therapeutics have broken new boundaries in pricing, too.
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