Thu.Apr 25, 2024

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Optimizing Bispecific Antibodies in Multiple Myeloma for Efficacy, Safety

Drug Topics

A Q&A with Kirollos Hanna, PharmD, director of pharmacy at Minnesota Oncology, on the current and future landscape of bispecific antibodies in myeloma treatment.

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Study Finds Relationship Between Uncontrolled Severe Asthma, Exacerbations and Health Care Resource Use

Pharmacy Times

The findings emphasize a need for guideline-based care delivery for patients with severe asthma, particularly for patients who are facing social disparities within health care.

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Trending Sources

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American Heart Association Launches Initiative to Include Pharmacists in Atrial Fibrillation Care

Drug Topics

Despite a wealth of knowledge, pharmacists are frequently not consulted as part of the decision-making team in atrial fibrillation management.

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Early tests of H5N1 prevalence in milk suggest U.S. bird flu outbreak in cows is widespread

STAT

Andrew Bowman, a veterinary epidemiologist at Ohio State University, had a hunch. He had been struck by the huge amounts of H5N1 virus he’d seen in milk from cows infected with the bird flu and thought that at least some virus was getting off of farms and going downstream — onto store shelves. He knew the Food and Drug Administration was working on its own national survey of the milk supply.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Voices in Pharmacy: April 2024 Expert Interviews

Drug Topics

Check out these featured Drug Topics expert interviews from April 2024.

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Amae Health picks up $15M to scale in-person clinics providing care for severe mental illness

Fierce Healthcare

Amae Health launched in January 2022 to improve care for individuals with severe mental illness through a community-based, integrated approach. | Amae Health, which opened its first outpatient clinic in Los Angeles 18 months ago, closed a $15 million series A round to fuel its growth as it plans to open new clinics in four markets.

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Pharmacists’ Role in the Diagnostic Stewardship Team

Drug Topics

With expertise through antimicrobial stewardship experience, researchers believe antimicrobial stewardship pharmacists are vital in assisting diagnostic stewardship.

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FDA Accepts sBLA for Dostarlimab With Chemotherapy to Treat Endometrial Cancer

Pharmacy Times

Dostarlimab plus chemotherapy is the only immuno-oncology-based therapy that showed statistically significant and clinically meaningful survival benefit in the overall patient population.

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STAT+: Generative AI is supposed to save doctors from burnout. New data show it needs more training

STAT

After stratospheric levels of hype, early evidence may be bringing generative artificial intelligence down to Earth. A series of recent research papers by academic hospitals has revealed significant limitations of large language models (LLMs) in medical settings, undercutting common industry talking points that they will save time and money, and soon liberate clinicians from the drudgery of documentation.

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Public Health Matters: Entrepreneurship, MedsPLUS Consulting, and Reaching Marginalized Communities

Pharmacy Times

Tune into this episode of “Public Health Matters” to learn about Dr. Pauline K. Long and her entrepreneurship journey, as well as how she creates meaningful impacts on patients in marginalized communities and within public health.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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STAT+: Why a British hospital, and not a drugmaker, is trying to get a rare disease therapy approved

STAT

LONDON — Claire Booth, a gene therapy researcher in London, had hoped that a biotech company would take her team’s work on an experimental medication for an ultra-rare children’s disease and get it to market. It didn’t happen. Now, in an unusual step, the hospital where she works is trying to get the medicine approved on its own.

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Cost of developing new drugs may be far lower than industry claims, trial reveals

The Guardian - Pharmaceutical Industry

Exclusive: MSF calls for transparency after its bill for a trial of TB treatment came to a fraction of the billions claimed by pharmaceutical companies Doctors have for the first time released details of their spending on a major clinical trial, demonstrating that the true cost of developing a medicine may be far less than the billions of dollars claimed by the pharmaceutical industry.

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With CEO search underway, Teladoc facing pressure to its BetterHelp DTC business, slowing telehealth growth

Fierce Healthcare

Teladoc acting CEO Mala Murthy sought to assure investors Thursday that the virtual care giant is poised for future growth even as it faces pressure in a saturated telehealth market. | Teladoc acting CEO Mala Murthy sought to assure investors Thursday that the virtual care giant has a sunny outlook for future growth even as it faces pressure in a saturated telehealth market.

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STAT+: Washington kicks into gear on H5N1

STAT

You’re reading the web edition of D.C. Diagnosis, STAT’s twice-weekly newsletter about the politics and policy of health and medicine.  Sign up here  to receive it in your inbox on Tuesdays and Thursdays. Why did the dairy cow cross state lines? After weeks of concern that the U.S. Department of Agriculture wasn’t doing enough to quell the spread of H5N1 bird flu, the agency announced Wednesday that it’s going to require testing for dairy cattle crossing sta

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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FDA Approves Generic OTC Naloxone Nasal Spray

Drug Topics

Amneal Pharmaceuticals said its generic naloxone hydrochloride nasal spray is now available in the US following FDA approval.

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Opinion: The grim reality of relocating to get access to gender-affirming care

STAT

In my work as a pediatric psychologist, I’ve been seeing a surge in the number of families with transgender or nonbinary children who are moving to Connecticut, where I live and work. In the past month, a real estate agent colleague has worked with 30 families with transgender children who were trying to find homes in central Connecticut, where they could get access to gender-affirming care.

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Hospital M&A studies highlight higher prices, tepid antitrust intervention

Fierce Healthcare

A pair of academic studies published this week painted an unflattering picture of the impact of hospital mergers and acquisitions on healthcare prices and regulators' track record of stepping in to | Two academic studies published this week sought to characterize cross-market deals and whether the FTC is taking a strong enough stance on blocking uncompetitive deals.

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Community Pharmacists Could Help Patients Control Diabetes Through Remote CGM Monitoring

Drug Topics

A new study found that cloud-based CGM monitoring services provided statistically significant improvements in high time above range, time in range, and average glucose.

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Evernorth's Accredo to offer Humira biosimilar at $0 out-of-pocket

Fierce Healthcare

Evernorth's Accredo arm will make a Humira biosimilar available to patients with no out-of-pocket costs, the company announced Thursday. | Evernorth's Accredo arm will make a Humira biosimilar available to patients with no out-of-pocket costs, the company announced on Thursday.

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STAT+: Vertex offers limited access to a cystic fibrosis drug in South Africa — and may undercut a court case

STAT

After months of sustained criticism, Vertex Pharmaceuticals reached an agreement to provide a pricey cystic fibrosis treatment in South Africa, but the move prompted a mixed reaction from consumer groups, some of which complained the deal is geared toward people with expensive health coverage. Under the arrangement, the company is making its Trikafta medication available through a government mechanism that allows a medicine that is not registered for sale in the country to be made available to i

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Study Highlights Reduced Disease Severity When Vaccinated Against RSV

Pharmacy Times

The severity of RSV disease among adults further highlights how crucial vaccine polices and recommendations are.

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STAT+: Amid layoffs and a hit to earnings, Bristol’s new CEO shares his vision for the future

STAT

Christopher Boerner, 53, took over as the chief executive officer of Bristol Myers Squibb last November, and immediately made a big move: a series of three acquisitions totaling $24 billion that would give BMS a new schizophrenia drug, a targeted cancer medicine, and radiopharmaceuticals used to treat cancer. On Thursday, Bristol released first quarter earnings and showed the price for those acquisitions.

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Does Adderall expire? What you need to know.

The Checkup by Singlecare

Pharmaceuticals have expiration dates. Adderall falls into this category. Labeled as a controlled substance , Adderall contains amphetamine and dextroamphetamine. Both are amphetamine salts that belong to a class of drugs known as central nervous system ( CNS ) stimulants. However, when prescription drugs are in short supply—as with the recent Adderall shortage —many patients who need this stimulant medication may be tempted to take old pills they find, hoping that’s better than nothing.

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WuXi AppTec denies client data sharing allegations and defends industry integrity

Outsourcing Pharma

Wuxi AppTec says recent allegations made by the US government that it has shared clients' data with Beijing without consent are âmisleadingâ and âinaccurateâ.

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STAT+: Bernie Sanders targets ‘outrageously high price’ of Ozempic

STAT

Want to stay on top of the science and politics driving biotech today?  Sign up  to get our biotech newsletter in your inbox. Good morning. Here in Chicago, residents are reeling over the  removal of the famed rat hole,  a rat-shaped indentation on a piece of sidewalk that drew crowds, fans, and even a proposal and a marriage. The need-to-know this morning AstraZeneca reported first-quarter  sales and profits  that topped analyst estimates, buoyed by its blockb

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OPC Summer 2024: Connecting Oncology Pharmacists With Cutting-Edge Insights and Opportunities to Collaborate

Pharmacy Times

This year’s event from June 20 to 21, 2024, in Austin, Texas, will offer 4.25 BCOP CE hours.

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STAT investigative series ‘Denied by AI’ wins major journalism prizes

STAT

Dear Readers, Please bear with me as I brag about two of STAT’s most accomplished (and humble) reporters: Casey Ross and Bob Herman.

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One2Treat - observing emerging trends and reshaping approaches to R&D

Outsourcing Pharma

Last month, OSP was excited to write about One2Treat, a progressive startup specializing in digital health solutions, which has launched a forward-thinking approach aimed at tackling key challenges in the biopharma industry.

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Owlet taps Wheel to bring infant monitoring device to parents through telehealth

Fierce Healthcare

Owlet is bringing its infant vitals monitoring product directly to caregivers through a new partnership with popular telehealth engine, Wheel, it announced Thursday. | Parents can now get a prescription for Owlet's FDA-cleared infant monitoring device through its just-launched telehealth platform, BabySat, powered by Wheel. The company intends to safeguard its rapid access prescriptions through a rigorous provider verification process.

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AstraZeneca CEO says platform deals largely done after M&As in vaccines, radioligand, cell therapy

Fierce Pharma

After AstraZeneca’s recent acquisitions of various technologies across different therapeutic areas, some investors started to wonder if the British pharma is stretching too thin. | After AstraZeneca’s recent acquisitions of various technologies across different therapeutic areas, some investors started to wonder if the British pharma is stretching too thin.

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Software as a Service to Elevate Patient Care in the Pharmacy

Drug Topics

Nicolette Mathey, PharmD, founder of ATRIUM24 and DottiCRM, discussed software as a service within the pharmacy.

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Novo Nordisk lands back in Sanders' crosshairs, this time over steep costs of Ozempic and Wegovy

Fierce Pharma

Just a few months after laying into CEOs from Bristol Myers Squibb, Merck & Co., and Johnson & Johnson about the high costs of their drugs, Sen. | Just a few months after laying into CEOs from Bristol Myers Squibb, Merck & Co. and Johnson & Johnson about the high costs of their drugs, Sen. Bernie Sanders, I-Vermont, is taking Novo Nordisk to task for allegedly turning its blockbuster GLP-1s Ozempic and Wegovy into “luxury goods.

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Eli Lilly Purchases Nexus Pharmaceutical Injectables Manufacturing Plant

Pharmaceutical Commerce

The deal further grows the Big Pharma company’s US production capabilities, especially when it comes to global parenteral products.

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Merck CEO Davis dubs Keytruda market exclusivity loss as 'more of a hill than a cliff'

Fierce Pharma

Merck touted newly approved Winrevair and what the emergence of the potential blockbuster means for the company as it faces the LOE of Keytruda.

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