Thu.Jan 25, 2024

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T2D Remission Through Weight Loss Linked With Lower Rates of Chronic Kidney, Cardiovascular Disease

Drug Topics

A study found that patients with type 2 diabetes who showed evidence of any remission had a 33% lower rate of chronic kidney disease, and a 40% lower rate of the composite cardiovascular disease measure.

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HPV vaccine study finds zero cases of cervical cancer among women vaccinated before age 14

STAT

A historic new study out of Scotland shows the real-world impact of vaccines against the human papillomavirus: The country has detected no cases of cervical cancer in women born between 1988-1996 who were fully vaccinated against HPV between the ages of 12 and 13. Many previous studies have shown that HPV vaccines are extremely effective in preventing cervical cancer.

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Dupilumab Approved by FDA to Treat Eosinophilic Esophagitis in Children Under 12

Drug Topics

Eosinophilic esophagitis is a chronic, progressive disease thought to be responsible for damaging the esophagus, and it can severely impact a child’s ability to eat.

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Merck CEO refused to testify in Senate because he’s not an expert in drug pricing, Bernie Sanders says

STAT

WASHINGTON — Sen. Bernie Sanders on Thursday jabbed the CEO of Merck for telling congressional staff that he didn’t have the expertise to testify at a Senate hearing on prescription drug prices because he’s a tax attorney. Sanders, who has threatened to subpoena the CEOs of Merck and Johnson & Johnson over their refusal to testify at a hearing on why drug prices are higher in the United States than other countries, told reporters the reasons the companies gave ranged fro

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Humana's stock tumbles pre-market as it posts $541M loss in Q4

Fierce Healthcare

Humana primed the pump last week for a disappointing fourth quarter call, and its stock again dropped Thursday morning as the company posted a $541 million loss. | Humana primed the pump last week for a disappointing fourth quarter call, and its stock again dropped Thursday morning as the company posted a $541 million loss.

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Transgender women’s higher risk for HIV is influenced by discrimination, CDC finds

STAT

Transgender women, in particular those belonging to marginalized racial and ethnic groups, have disproportionately high rates of HIV. Yet so far, no standardized surveillance system has collected data that could provide insight into the factors that put people at higher risk for contracting the virus. A survey of transgender women, developed by the Centers for Disease Control and Prevention, aimed to gather and assess behavioral data in relation to HIV prevention and risk for the first time.

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Two genomics powerhouses team up to expand infectious disease surveillance

STAT

LONDON — Two research centers that have been at the forefront of following the evolution of the SARS-CoV-2 coronavirus — one in the U.K. and one in South Africa — have teamed up on a partnership that they say will expand their efforts to track emerging disease threats around the world. The collaboration between the U.K.’s Wellcome Sanger Institute and South Africa’s Centre for Epidemic Response and Innovation, announced Thursday, comes as much of the infrastruc

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Isaac Health nabs $5.7M seed round to scale up virtual brain health and dementia care

Fierce Healthcare

The U.S. faces a growing shortage of neurologists, creating care "deserts" around the country, forcing patients to wait longer and drive further to receive care. | Digital health company Isaac Health launched in 2022 to provide a virtual brain health and memory clinic platform with the goal of improving access to constrained brain health services.

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Opinion: Other states should follow New Jersey’s lead on prior authorization reform

STAT

Imagine this scene: You are a cancer patient already navigating fear and uncertainty around your treatment, when you inexplicably cannot access the care recommended by your cancer doctor. This turns out to be because of a perverse hurdle imposed by your insurance company — called a prior authorization — that ends in a denial of care.

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CMS seeks input on improving transparency in Medicare Advantage

Fierce Healthcare

The Centers for Medicare & Medicaid Services is seeking feedback on how to increase transparency around Medicare Advantage and improve data capabilities. | CMS initiated a request for information period Thursday to receive data on all aspects of the Medicare Advantage program including prior authorizations, value-based care and vertical integration.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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Zyn scrutiny from Sen. Chuck Schumer prompts an unlikely culture war

STAT

Senate Majority Leader Chuck Schumer (D-N.Y.) wants the federal government to investigate Zyn nicotine pouches. Schumer is no stranger to calling for crackdowns on popular products — he’s done similar with Four Loko and Logan Paul’s line of energy drinks. The problem for Schumer this time around is that many users of Zyn are very passionate, and very, very online.

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Amid high-profile CAR-T safety probe, FDA’s Peter Marks offers first glimpse at data under review

Fierce Pharma

Three months after launching an investigation into the risk of patients developing secondary T-cell cancers after receiving a CAR-T drug, the FDA has shared more information on the cases it has see | Three months after launching an investigation into the risk of secondary T-cell cancers after treatment with a CAR-T medicine, the FDA has shared more information on the cases that it has seen.

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Amazon Pharmacy testing out medication consulting service with One Medical primary care providers

Fierce Healthcare

As Amazon builds out its healthcare business and expands its reach into hybrid primary care, pharmacy operations and virtual care, there are promising opportunities to integrate these services to o | A year after its big-ticket primary care acquisition, Amazon Pharmacy is piloting a program to provide pharmacy consultations to One Medical providers with a specific focus on high-risk and complex patients among the older senior population.

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STAT+: CVS wants to become a medical powerhouse. Will long lines and understaffing hold it back?

STAT

CVS Health is perhaps best known for two things. First, there are the comically long receipts that have inspired hundreds of internet memes. And then there’s the ubiquitous presence of its stores. If it seems like there’s a CVS pharmacy on every other block, that’s because the company operates 9,000 stores nationwide, including nearly 500 across Massachusetts.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Season 3 - Public Health Matters: A Look at Wearable Technology, AI-Assisted Innovations

Pharmacy Times

Tune in to this special episode for an exclusive insight into the future of health technology and wearable innovation, including a glimpse into the world of CES 2024.

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Payer Roundup–L.A. Care Health Plan addressing PPE shortages; new Cost Plus Drugs partnership

Fierce Healthcare

Below is a round-up of payer-centric news for the week of Jan. 22, 2024 | This week, California health plans formed a coalition to address long-term PPE shortages, Mark Cuban's drug company announced a new partnership with Livinity, popularity rises for Colorado's public option plans and more.

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FDA Approves Dupilumab for Pediatric Patients with Eosinophilic Esophagitis

Pharmacy Times

The approval marks dupilumab as the first and only FDA-approved medicine to treat pediatric patients with eosinophilic esophagitis.

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STAT+: Humana projects a tough road for Medicare Advantage, sinking its stock

STAT

Humana’s Medicare Advantage business is faring even worse than the company let on last week , with “unprecedented” numbers of older adults getting medical care and busting through its tactics for holding up payment. The country’s second largest private Medicare insurer disclosed Thursday it’s projecting roughly half the profit in 2024 that investors had expected.

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Understand the Fundamentals of Treating Older Patients with Atopic Dermatitis

Pharmacy Times

Treating older patients requires a greater focus on treating their AD without exacerbating their comorbidities.

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Most clinicians believe hospitals should address climate change, Commonwealth Fund survey finds

Fierce Healthcare

Four in five clinicians believe it’s important for their hospital to address climate change and that doing so is aligned with their organization’s mission, a new

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Who are the 50 most influential leaders in pharmacy?

Drug Store News

The Pharmacy 50 program, launched in 2021 by The Pharmacy Podcast Network, is recognizing individuals that have had a significant impact on the accomplishments of others in pharmacy.

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Chapter 11 bankruptcies spiked across healthcare in 2023, particularly for hospitals

Fierce Healthcare

2023 was the biggest year for healthcare Chapter 11 bankruptcy filings in the past half-decade, according to a new research report from Gibbins Advisors. | There were 79 bankruptcy filings across healthcare-related sectors last year, 12 of which were hospitals. Those are both up from 2022's 46 total and two hospital filings, according to a new report.

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STAT+: A PBM in Africa flips the industry’s script in a bid to make people healthier

STAT

WASHINGTON — For an app that helps pharmacies in Africa manage their medicines, the term “pharmacy benefit manager” has become a dirty word. The organization, called Maisha Meds, plays the role of a middleman between international groups like USAID and the Gates Foundation and pharmacies. By definition, it’s a PBM. But since it’s a nonprofit company and it subsidizes medicines and tests aimed at promoting public health, it’s hesitant to describe itself t

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Trust and treatment: GenAI in life sciences in 2024

pharmaphorum

Discover the role of GenAI in life sciences in 2024. Explore how artificial intelligence and machine learning techniques like GenAI are revolutionising drug development, diagnostics, and research. Learn how industry leaders, including Google, are leveraging GenAI to advance healthcare and enhance patient outcomes.

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PTC's re-examination bid for DMD drug Translarna falls short in Europe

Fierce Pharma

A decade after Translarna's initial marketing authorization in Europe, it looks like the drug's run in the region is coming to an end. | A decade after Translarna's initial marketing authorization in Europe, it looks like the drug's run in the region is coming to an end.

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What are the side effects of Zyrtec in older adults?

The Checkup by Singlecare

Zyrtec (cetirizine) is one of the most commonly used over-the-counter antihistamines for treating seasonal and environmental allergies. It’s part of the second generation of antihistamines developed after medications like Benadryl (diphenhydramine) and Dramamine (dimenhydrinate). It works just as well against allergies but with less sedating side effects.

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How manufacturing keeps pace with innovation in cell and gene therapy

pharmaphorum

On today’s podcast, host Jonah Comstock is joined by Arturo Araya, EVP of commercialisation at Cellares, a company that is attempting to create a new kind of contract manufacturing organisation for the rapidly crystalizing world of cell and gene therapy.

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STAT+: As biotech VCs struggle to raise money, some debate whether the worst is over

STAT

Over the last year or two, something curious has started occurring in the conference rooms and private Zoom meetings of biotech venture capitalists. Representatives from pension funds, college endowments, family offices, and other organizations with money to invest have become bolder in their requests, according to interviews with a host of VCs. They’re pushing not only for advantageous terms in a VC firm’s latest fund, but in some cases, have angled for equity in the firm itself.

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Mental Wellness: Pharmacists and Mental Health Teams Could Aid Positive Patient Outcomes

Pharmacy Times

Gabriella Farkas, MD PhD, addresses the multifaceted role of pharmacists in the mental health and wellness space

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STAT+: Key Senate panel considers Medicare bonuses for hospitals that prevent drug shortages

STAT

WASHINGTON — A key Senate committee is proposing that Medicare pay bonuses to hospitals that take measures to prevent drug shortages. It also wants to change the way doctors are paid to administer drugs in outpatient settings. After a startling number of drugs, including chemotherapies, were in shortage last year, Washington stepped up its efforts to find policy solutions for the problems.

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EU plan for medicine stockpile could worsen UK’s record shortages

The Guardian - Pharmaceutical Industry

Bloc plans to bulk-buy key drugs for all 27 countries, potentially leaving Britain ‘behind in the queue’ The EU is to stockpile key medicines that will worsen the record drug shortages in the UK, with experts warning that the country could be left “behind in the queue”. The EU is seeking to safeguard its supplies by switching to a system in which its 27 members work together to secure reliable supplies of 200 commonly used medications, such as antibiotics, painkillers and vaccines.

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Bernie Sanders’ showdown with pharma CEOs is coming to a head

STAT

You’re reading the web edition of D.C. Diagnosis, STAT’s twice-weekly newsletter about the politics and policy of health and medicine.  Sign up here  to receive it in your inbox on Tuesdays and Thursdays. Bernie’s subpoena showdown We’re less than a week away from a scheduled vote on subpoenaing the CEOs of two drugmakers, J&J and Merck.

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Elation Health, Surescripts partner to provide medication cost, coverage details during patient visits

Fierce Healthcare

Elation Health, a company that developed electronic medical record technology for primary care clinicians, is expanding its partnership with Surescripts to bring more transparency around prescripti | Elation Health integrated Surescripts' real-time prescription benefit tool directly into its EHR to give providers access to patient-specific medication coverage and cost data during patient medical visits.

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In downsizing mode, Sage will move headquarters to a smaller space

Fierce Pharma

Two months ago, in presenting quarterly earnings, CEO Barry Greene said Sage Ther | Two months ago, in presenting quarterly earnings, CEO Barry Greene said Sage Therapeutics was on its way to becoming a “leaner and stronger company.” Part of that mission will come to fruition later this year with a move of its headquarters in Cambridge, Massachusetts.

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