Fri.Aug 11, 2023

article thumbnail

MorningRX: August 11, 2023

Drug Topics

HHS awards money to fight the nursing shortage, the FDA approves Johnson & Johnson's talquetamab-tgvs (TALVEY), and the CDC says suicides reached an all-time high in 2022.

FDA 187
article thumbnail

Estrogen Impacts the Effects of Psilocybin for Women

Pharmacy Times

Jennifer Chesak, author of The Psilocybin Handbook for Women, discusses how estrogen can affect binding at the serotonin receptor sites, causing psilocybin to impact women’s bodies differently.

123
123
Insiders

Sign Up for our Newsletter

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Trending Sources

article thumbnail

Fallopian Tube Removal Not Associated With Ovarian Cancer Risk

Drug Topics

A substantial collection of evidence indicates that the fallopian tube serves as the primary site of origin for a large portion of high-grade serous ovarian cancers.

98
article thumbnail

Expert Discusses Current Recommendations for Respiratory Syncytial Virus, Influenza, COVID-19 Vaccination

Pharmacy Times

Gretchen Garofoli, PharmD, an associate professor at the West Virginia School of Pharmacy, discusses the current recommendations for COVID-19, respiratory syncytial virus (RSV), and influenza vaccines and vaccine hesitancy.

Vaccines 123
article thumbnail

Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

article thumbnail

ADHD Medication Shortages Raise Concerns Among Young Patients and Their Families

Drug Topics

According to the National Community Pharmacists Association, 97% of independent pharmacy owners reported shortages of Adderall in early 2023.

article thumbnail

Significant Increase in Hospital Delirium, New Antipsychotic and Benzodiazepine Prescriptions Associated With COVID-19 Pandemic

Pharmacy Times

Unexpectedly, the highest increases in delirium compared to projections were in the 66 to 74 years of age group, which could have important personal and societal repercussions, such as earlier development of dementia.

Hospitals 123

More Trending

article thumbnail

Driving Patient Safety With New Pharmacy HIT Standards

Pharmacy Times

New standards from the National Council for Prescription Drug Programs could drive changes that improve patient safety by optimizing drug therapy to reduce the risk of harm and improve health and well-being before a medication is dispensed.

123
123
article thumbnail

Supreme Court blocks Purdue Pharma's bankruptcy settlement, threatening immunity to Sackler family

Fierce Pharma

It’s been a rough summer for pharmaceutical companies trying to resolve lawsuits by declaring bankruptcy. | The Supreme Court has halted Purdue Pharma’s $6-billion bankruptcy settlement, which granted the company’s former owners—the Sackler family—immunity from civil suits related to the opioid crisis.

article thumbnail

Low Probability of 5% Weight Loss in Adults With Overweight or Obesity

Pharmacy Times

Despite the low uptake of healthy lifestyle behaviors to achieve 5% weight loss or greater, the probability of weight loss increased among individuals with higher initial BMI.

123
123
article thumbnail

Microsoft partners with Epic to roll out EHR cloud database solution, starting with Mount Sinai

Fierce Healthcare

Microsoft rolled out a new electronic health records cloud database solution, leveraging Azure Large Instances, that enables health systems to scale capacity for high-volume workloads. | Microsoft rolled out a new electronic health records cloud database solution, leveraging Azure Large Instances, that enables health systems to scale capacity for high-volume workloads.

98
article thumbnail

What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

article thumbnail

Encorafenib, Binimetinib Combination Improves Progression-Free Survival for Patients With BRAF-Mutant Melanoma

Pharmacy Times

In the COLUMBUS study, the FDA requested that the investigators evaluate the contribution of binimetinib while maintaining the same dosage of encorafenib at 300 mg to confirm the benefits of the combination.

Dosage 122
article thumbnail

Bird flu researchers turn to Finland’s mink farms, tracking a virus with pandemic potential

STAT

HELSINKI — It was the quiet that stood out to Tarja Sironen at the fur farm. A specialist in emerging infectious diseases, Sironen has conducted research at fur farms for years. She helped develop a Covid vaccine that was deployed to the country’s mink population during the pandemic. She knows the industry well.

article thumbnail

Amyloid-Targeting Class of Alzheimer Disease Drugs Show Potential, Raise Concerns of Accessibility for Diverse Patients

Pharmacy Times

Advancements in the development of amyloid-targeting monoclonal antibodies show promise for treating Alzheimer disease, but there have been concerns around cost, adverse reactions, and inequity of care for marginalized patients.

article thumbnail

Bridging the Divide: Medical's Omnichannel Momentum

PharmExec

How pharma medical affairs and commercial teams are synchronizing their capabilities to boost omnichannel marketing strategies and better understand customer engagement needs.

98
article thumbnail

5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

article thumbnail

Humira Biosimilar Effective in Treating Moderate to Severe Chronic Plaque Psoriasis

Pharmacy Times

Although SB5 is an effective treatment for plaque psoriasis, it is recommended that patients consider the potential risks and adverse effects.

122
122
article thumbnail

Amylyx's ALS drug Relyvrio gets off the ground as company eyes new brain disorder

Fierce Pharma

Amylyx Pharmaceuticals’ amyotrophic lateral sclerosis (ALS) drug Relyvrio continues to wow Wall Street. | Amylyx’s amyotrophic lateral sclerosis drug Relyvrio ​​​​​​​continues to wow Wall Street. The drug brought in $98.2 million revenue in the second quarter, handily beating analysts’ consensus estimates of below $92 million.

98
article thumbnail

Technician Product Verification Benefits Patients, Pharmacists, Technicians

Pharmacy Times

Pharmacy technicians are stepping up to assume expanded responsibilities that contribute to pharmacy management and patient safety.

123
123
article thumbnail

7 ways to relieve diverticulitis pain fast

The Checkup by Singlecare

Pain management is essential to the treatment plan when someone is suffering. However, figuring out the right course of action for a particular condition can be difficult. There are many ways to worsen and prolong pain if not managed properly. People with diverticulitis often experience abdominal pain during or after eating a meal. Eating is a part of everyday life, so coping with a condition that is worsened by eating can be challenging.

98
article thumbnail

Ambulatory Care Pharmacist-Administered Depression Screenings Can Close Gaps in Care

Pharmacy Times

The study implemented a novel workflow for ambulatory care pharmacists to execute pharmacist-administered depression screenings.

122
122
article thumbnail

Tuberculosis outbreak tied to bone grafts underscores shortcomings of testing

STAT

One person has died and at least four have been sickened by tuberculosis in infected bone materials, an outbreak that has cast a spotlight on the shortcomings of testing for such tissue products. It’s the second tuberculosis outbreak linked to the biomaterial device company, Aziyo Biologics. In 2021, Aziyo’s product killed eight people after orthopedic and dental surgeons unwittingly implanted infected bone grafts into patients.

FDA 98
article thumbnail

'Like a dairy farm treats cows': Henrietta Lacks' estate hits Ultragenyx with gene therapy vector lawsuit

Fierce Pharma

Less than a month after the family of Henrietta Lacks reached a settlement with Thermo Fisher over its use of Lacks’ cells, another drugmaker stands accused of profiting from a racist medical syste | Less than a month after the family of Henrietta Lacks reached a settlement with Thermo Fisher over its use of Lacks’ cells, another drugmaker stands accused of profiting from a racist medical system.

98
article thumbnail

STAT+: More hospital pharmacists are rationing drugs due to increasing shortages

STAT

Nearly every hospital pharmacy across the U.S. is experiencing shortages of prescription drugs. And the problem has become so bad – especially for chemotherapies — that one-third of hospital pharmacists reported their institutions are rationing, delaying, or canceling treatments or procedures, according to a new survey. Specifically, 99% of hospitals pharmacists reported shortages, which is causing 85% to ration treatments and 84% to rely on different dosages.

article thumbnail

Medicaid coverage for substance abuse treatment improved substantially since 2014: study

Fierce Healthcare

Access to care for Medicaid fee-for-service beneficiaries with substance use disorder has improved from 2014 until 2021, but much more can be done to improve it further, researchers say. | There have been substantial improvements in coverage for substance use disorder and opioid use disorder since 2014, according to a study in JAMA Network. Nonetheless, there’s room for yet more improvement.

98
article thumbnail

A Fierce Focus On Unmet Need

PharmExec

From public defender to spearheading the adoption of innovative drugs, Wendy Short Bartie, senior VP and general manager for the hematology and cell therapy division at Bristol Myers Squibb, has remained a steadfast patient advocate—working to fulfill unmet medical needs and bring treatments to as many people as possible.

98
article thumbnail

Propranolol for anxiety: Does it work?

The Checkup by Singlecare

Propranolol is an old drug that just won’t go away, for good reason. It touts a 50-year history of utility, originally as a treatment for heart disease and later as a preventive treatment for migraine, a use that has landed it on the World Health Organization’s list of essential medications. A role for propranolol that you may find more interesting is in the treatment of anxiety.

Dosage 98
article thumbnail

Another round of layoffs hits BMS, with 100+ people impacted after earnings miss

Fierce Pharma

Bristol Myers Squibb has laid off more than 100 employees amid a reconfiguration of expenses that follows disappointing earnings results. | Bristol Myers Squibb has laid off more than 100 employees amid a reconfiguration of expenses that follows disappointing earnings results.

98
article thumbnail

Opinion: Philanthropic endowments at universities can offer a way out of biotech’s Valley of Death

STAT

So many promising medical innovations never reach their full potential as therapies or cures, languishing instead in a metaphoric place many of us in biotech know as “the Valley of Death.” This valley represents the gap between when a scientist makes a discovery and when that work has reached the point when a pharmaceutical company will license it, or a venture capital firm will invest in it, to get it to the point to help the patients who need it.

article thumbnail

DOJ taking a closer look at UnitedHealth's $3.3B bid for Amedisys

Fierce Healthcare

The Department of Justice (DOJ) is requesting more information from Amedisys regarding its proposed $3.3 billion deal to be acquired by UnitedHealth Group, which pushes back the timing of the deal. | The Department of Justice is requesting more information from Amedisys regarding its proposition $3.3 billion acquisition by UnitedHealth Group, which pushes back the timing of the deal.

98
article thumbnail

Non-fatal overdose risk higher when opioid agonists prescribed with other medicines

Hospital Pharmacy Europe

The risk of overdose from prescribed medicines used to overcome drug addiction is higher when patients are taking other medication, such as opioid agonists, according to a new study from the University of Manchester. In some cases, patients were more than twice as likely to be hospitalised with an overdose if they were taking opioid agonists in combination with prescribed drugs to treat mental health conditions or relieve pain, such as benzodiazepines, gabapentinoids, antipsychotics or Z-drugs

article thumbnail

Endo sues Zydus in attempt to block its generic version of Chantix

Fierce Pharma

Since Pfizer’s smoking cessation drug Chantix was recalled in 2021, Endo's subsidiary Par Pharmaceuticals has been the only one to market the product. | Endo alleges that Zydus Pharmaceuticals infringed upon its Chantix patent, asserting that there is no alternative method for producing the drug without the impurities that led to the removal of Pfizer's original product from the market.

98
article thumbnail

STAT+: White House drug shortages task MIA with lawmakers while Congress works on fixes

STAT

WASHINGTON — A White House task force created to work on drug shortage reforms has yet to contact the lawmakers who are writing legislation to stem shortages — and it’s not clear when the task force will recommend policies. The White House formed a task force at the beginning of 2023 to deal with the issue of persistent drug shortages.

article thumbnail

How long after taking ibuprofen can you drink alcohol?

The Checkup by Singlecare

After an evening that included sipping some alcoholic drinks, you may want to pop a few ibuprofen to ward off a hangover the next day. Or maybe you took a couple of ibuprofen earlier in the day, and now you’re craving a beer. But the question is, should you do that? How long after taking ibuprofen can you drink alcohol? Experts suggest combining alcohol and ibuprofen can raise the risk of serious side effects, including kidney damage and liver problems and gastrointestinal bleeding.

article thumbnail

Fresenius Kabi launches generic Mozobil

Drug Store News

Plerixafor injection is a hematopoietic stem cell mobilizer used in combination with granulocyte-colony stimulating factor in patients with non-Hodgkin's lymphoma or multiple myeloma.

97
article thumbnail

UnitedHealth was Q2's most profitable payer. Here's what its rivals earned

Fierce Healthcare

While major payers issued warnings to investors ahead of second-quarter earnings about rising utilization rates, patients returning to deferred services did not prevent these companies from turning | While major payers issued warnings to investors ahead of second-quarter earnings about rising utilization rates, patients returning to deferred services did not prevent these companies from turning a profit.

97