Fri.Dec 29, 2023

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We wish we’d written that: STAT staffers share their favorite stories of 2023

STAT

It’s time to take stock of the year that was in health and science: the meteoric rise of weight loss drugs , the approval of the first CRISPR-based therapy , the continuing effects of abortion access restrictions after the Dobbs decision, and much more. Below is our annual list of stories that STAT staffers loved, and wish that they had written.

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Devoted Health closes out 2023 with $175M series E funding round

Fierce Healthcare

Tech-enabled Medicare Advantage startup Devoted Health is closing out 2023 with $175 million in fresh funding, marking one of the largest funding rounds of the year. | Tech-enabled Medicare Advantage startup Devoted Health is closing out 2023 with $175 million in fresh funding, marking one of the largest funding rounds of the year.

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Opinion: There’s a less intimidating alternative to EpiPens for dangerous allergic reactions. Why won’t the FDA approve it?

STAT

My son Thomas has carried around a needle since he entered kindergarten at the age of 5. That was a big responsibility for a small child to carry an injector loaded with lifesaving epinephrine, but since he was 19 months old, he has worked with our entire family to manage his anaphylactic food allergies, asthma, and eosinophilic esophagitis. We are not alone.

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Regeneron fends off Viatris' Eylea biosimilar with patent win

Fierce Pharma

Armed with a new victory over Viatris in a patent dispute, Regeneron can knock off one contender in the Eylea biosimilar race. | A West Virginia judge found that Viatris' proposed biosimilar stepped on one of the three patents that Regeneron sued over. Shortly after, the company expanded its suit against another biosimilar contender, setting the stage for Regeneron's defense in Eylea's last few months of exclusivity.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Fights over methadone, harm reduction, and more: 3 addiction stories to watch in 2024

STAT

The U.S. drug crisis is as bad as it’s ever been, and there are few signs things are getting better. About 110,000 people died of drug overdoses in 2023, about the same as in previous years. Fentanyl, the powerful synthetic opioid that now dominates the illicit drug market, remained the main culprit. Xylazine, the veterinary sedative known as “tranq,” only became more common.

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Top 5 Pharmacy Times Pediatrics Articles of 2023

Pharmacy Times

From newsworthy moments to groundbreaking research, these were the most-read pediatrics-related articles on Pharmacy Times in 2023.

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Top 5 Pharmacy Times Oncology Articles of 2023

Pharmacy Times

From newsworthy moments to groundbreaking research, these were the most-read oncology-related articles on Pharmacy Times in 2023.

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Eisai working on wristband sensor for brain amyloid

pharmaphorum

Eisai and Oita University have developed a machine learning-powered wearable that can predict whether someone is at risk of developing Alzheimer’s disease

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Opinion: Buprenorphine, autism diagnoses, and long Covid: the most-read First Opinion essays of 2023

STAT

In a year of abortion restrictions , biotech industry upheaval , and revolutionary drug approvals , First Opinion strived to publish the most surprising, provocative, and conversation-starting essays from a wide variety of contributors. Below, you’ll find our top six most-read articles of the year by page views. Why six instead of five? Because why not?

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Navigating transplant networks: Ensuring equitable access and improving outcomes for highly sensitised kidney transplant patients

pharmaphorum

Navigating transplant networks: Ensuring equitable access and improving outcomes for highly sensitised kidney transplant patients Mike.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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Creatine side effects and how to avoid them

The Checkup by Singlecare

Common creatine side effects | Serious side effects | Side effects timeline | Interactions | Safety warnings | How to avoid side effects | How to treat side effects Creatine is a naturally occurring amino acid that is vital to producing short-burst muscle energy. It’s also vital to brain function, muscle repair, muscle hydration, and the body’s production of hormones, such as estrogen, testosterone, and insulin.

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FDA warns of rare hypersensitivity reaction due to antiseizure drugs

Pharmaceutical Technology

FDA warns that levetiracetam and clobazam can cause DRESS, a rare hypersensitivity reaction which can be life threatening.

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Zyrtec side effects and how to avoid them

The Checkup by Singlecare

Common Zyrtec side effects | Serious side effects | Side effects timeline | Interactions | Safety measures | How to avoid side effects | How to treat side effects Zyrtec is an over-the-counter (OTC) antihistamine that temporarily relieves hay fever and allergy symptoms, such as runny nose, sneezing, and itchy, watery eyes. Zyrtec comes in a variety of dosage forms , including tablets, chewable tablets, liquid gel capsules, orally disintegrating tablets, and syrup.

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Enveric’s EB-003 selected as lead candidate for mental health disorders

Pharmaceutical Technology

Enveric Biosciences has selected EB-003 as its lead drug candidate from its EVM301 series for difficult-to-treat mental health disorders.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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The Top 5 Q&As of 2023

PharmExec

Pharm Exec spent the year speaking with some of the most interesting professionals from the life sciences industry.

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UnitedHealth to sell off Brazil business Amil

Fierce Healthcare

UnitedHealth Group has agreed to sell off its Brazilian health insurance business, Amil, to entrepreneur José Seripieri Filho, according to

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The smart-design evolution of the laboratory space

pharmaphorum

In this penultimate instalment of the five-part, festive series of the pharmaphorum podcast, host Nicole Raleigh speaks with Bobby Savarese, senior principal and business development director at Unispace Life Sciences, exploring how laboratory space requirements have changed since the pandemic.

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Top 5 Pharmacy Times Health Systems Articles of 2023

Pharmacy Times

From newsworthy moments to groundbreaking research, these were the most-read health systems-related articles on Pharmacy Times in 2023.

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Bright Health finalizes MA sale to Molina, amends credit facility

Fierce Healthcare

The sale of Bright Health Group's Medicare Advantage plans to Molina Healthcare has cleared the needed regulatory hurdles and is set to close on or about Jan. 1. | The sale of Bright Health Group's Medicare Advantage plans to Molina Healthcare has cleared the needed regulatory hurdles and is set to close on or about Jan. 1.

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New Year, New Goals: 2024

The Thyroid Pharmacist

Wow… do the years just fly by! I can’t believe that it’s been over 10 years since I started the thyroidpharmacist.com blog in 2013, and now 2023 is almost over. Around this time of year, I tend to be very introspective. I was visiting with my family and my mom commented about how quiet I have been… but I love this time of year… the end of the year is always a perfect opportunity to reflect, let go of the past, dream, and plan for the future.

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The Decline and Fall of the Clinician–Scientist

BioPharm

Clinician-Scientists are vital innovation spark plugs, accounting for 40% of Nobel awards in Physiology or Medicine, and two thirds of Big Pharma CSOs.

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CoQ10 side effects and how to avoid them

The Checkup by Singlecare

Common CoQ10 side effects | Serious side effects | CoQ10 and liver health | Side effects timeline | Interactions | Safety measures | How to avoid side effects | How to treat side effects Coenzyme Q10 (or CoQ10, CoQ, or vitamin Q10) is a vitamin-like molecule that is essential to cells’ ability to generate energy. It also has powerful antioxidant properties.

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Calculus’s Liz Klein: Investing in a changing landscape

pharmaphorum

To learn more, Deep Dive editor Eloise McLennan sat down with Calculus Capital’s investment director, Liz Klein, to discuss the dynamic world where capital meets compassion.

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Buspirone side effects and how to avoid them

The Checkup by Singlecare

Common buspirone side effects | Serious side effects | Side effects timeline | Interactions | Safety measures | How to avoid side effects | How to treat side effects Buspirone is a generic prescription drug that treats symptoms of anxiety disorders. Buspirone used to be sold under the brand name Buspar, which is no longer sold in the United States. People take a buspirone oral tablet two or three times per day, depending on their prescriber’s instructions.

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Replay Signs Exclusive Licensing Agreements with NIH and Miltenyi Biotec for Cell Therapy Development and Manufacturing

BioPharm

Through Syena, its oncology-focused product company, Replay will develop and manufacture T-cell receptor and natural killer cell therapies with the NIH and Miltenyi Biotec.

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Top 3 Manufacturing and Packaging Articles of 2023

Pharmaceutical Commerce

Popular works in the category explore 340B guidelines, ‘smart pharma’ capabilities, and commercialization trends.

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Episode 560: From Hallucinations to Healing? The psilocybin evidence

Therapeutics Education Collaboration

In episode 560, Mike and James finish their discussion around the use of hallucinogens/psychedelics by going over the psilocybin evidence. As with ketamine we cover the many limitations of the evidence around psilocybin and also talk about the side effects, costs and inconvenience. So now you know all we know for what that is worth. Show notes HANDOUT From Hallucinations to Healing: The Rise of Novel Mental Health Therapies In episode 560, Mike and James finish their discussion around the use of

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Fourteen Individuals Participate in Inaugural PQA Quality Shadowing Program

PQA

To build a larger and more diverse quality workforce, the PQA Quality Shadowing Program provides individuals from diverse groups the opportunity to observe certain nomination-based panels to gain knowledge that can support selection for future panels. This opportunity is designed for early career professionals and individuals who are interested in quality but have not had opportunities to participate in formal PQA measure development and stewardship activities.

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Virtual Clinical Trial Companies: Bringing Revolution in Medical Research

Roots Analysis

Clinical trials are prospective biomedical research studies designed to evaluate medical, surgical or behavioral interventions in people and investigate novel approaches for the diagnosis and prevention / treatment of diseases. In order to gain marketing approval from regulatory authorities for a novel therapeutic intervention, highly accurate and elaborate clinical trial data is required to validate the drug’s safety and effectiveness towards a specific target indication.