Cannabinoids show promise in acute migraine clinical trial
pharmaphorum
MARCH 4, 2024
Inhaled cannabinoids have been shown to perform better than placebo in providing pain relief for people suffering from acute migraine in a clinical trial
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pharmaphorum
MARCH 4, 2024
Inhaled cannabinoids have been shown to perform better than placebo in providing pain relief for people suffering from acute migraine in a clinical trial
Pharmacy Times
JUNE 30, 2023
Galcanezumab-gnlm (Emgality; Eli Lilly and Company) did not demonstrate superiority to rimegepant orally disintegrating tablet (Nurtec ODT) on the percentage of individuals achieving a 50% or greater reduction in monthly migraine headache days.
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Pharmacy Times
JANUARY 4, 2023
There is a growing body of evidence that foods, substances, and additives in vitamins and supplements can be a trigger for migraine headaches.
Hospital Pharmacy Europe
AUGUST 23, 2023
Atogepant is the first and only once-daily oral calcitonin gene-related peptide (CGRP) receptor antagonist (gepant) approved in the European Union (EU) for the prophylaxis of migraine in adults. In the UK, draft guidance from NICE has approved another oral gepant, rimegepant, for episodic migraine. days with atogepant compared to 5.1
European Pharmaceutical Review
SEPTEMBER 14, 2023
Rimegepant (Vydura) is the “first and only NICE-recommended medicine that can help alleviate the misery of acute migraines, and may be considered a step-change in treatment,” shared Helen Knight, Director of medicines evaluation at the National Institute for Health and Care Excellence (NICE).
European Pharmaceutical Review
NOVEMBER 17, 2023
Results from AbbVie’s Phase III study, PRODROME , published in The Lancet showed that UBRELVY ® (ubrogepant) 100mg for acute treatment of migraine significantly reduced the likelihood of development of moderate or severe headache compared to placebo within 24 hours post-dose.
Pharmafile
DECEMBER 6, 2023
Teva Pharmaceuticals has announced data from a post hoc analysis of two phase 3 clinical studies around the effectiveness of migraine prevention treatment, Ajovy (fremanezumab) in the reduction of migraine attacks in patients with migraine and co-morbid obesity.
European Pharmaceutical Review
AUGUST 17, 2023
Recent EU approval means adults who have four or more migraine days per month can now access the first and only once-daily oral calcitonin gene-related peptide (CGRP) receptor antagonist (gepant). This was compared to 27 percent of patients in the placebo arm. This result was compared to 29 percent of participants given placebo.
Pharmaceutical Technology
JUNE 1, 2023
The UK’s National Institute for Health and Care Excellence (NICE) has issued final draft guidance recommending the use of Pfizer ’s rimegepant (Vydura) to prevent migraine attacks. NICE medicines evaluation director Helen Knight said: “Each year, the lives of millions of people in England are blighted by migraine attacks.
European Pharmaceutical Review
JUNE 1, 2023
An oral treatment for preventing migraines has been recommended by the National Institute for Health and Care Excellence (NICE) for the first time. Rimegepant (Vydura) is recommended as an option for episodic migraine in adults after having at least three previous failed preventive treatments. How does the oral migraine treatment work?
Hospital Pharmacy Europe
SEPTEMBER 14, 2023
NICE has approved rimegepant (brand name Vydura) as the first treatment for acute migraine, in draft guidance published today (14 September). It prevents the release of calcitonin gene-related peptide thought to be responsible for the severe pain associated with migraine attacks. NICE put the cost of the drug at £12.90
Pharmaceutical Technology
MARCH 10, 2023
The US Food and Drug Administration (FDA) has granted approval for Pfizer ’s Zavzpret (zavegepant) for the acute treatment of migraine in adult patients with or without aura. Zavzpret is claimed to be the first and only calcitonin gene-related peptide (CGRP) receptor antagonist nasal spray approved to treat migraine.
The Checkup by Singlecare
APRIL 4, 2024
Food and Drug Administration (FDA) used to treat and prevent migraine headaches. Migraine attacks are associated with raised levels of a protein called CGRP in the brain, and Nurtec works by blocking CGRP receptors from being activated. As a result, people can experience pain relief and improved migraine symptoms.
PharmaShots
JUNE 22, 2023
The results showed no statistical difference b/w women with migraine who used the device during pregnancy throughout 3mos. The device is a safe treatment for migraine during pregnancy, not increasing the risk for adverse pregnancy outcomes. postpartum, and for those who did not use during this period, 66.7% achieved pain relief @2hrs.
Hospital Pharmacy Europe
FEBRUARY 24, 2023
In a recent phase 2/3 trial, oral rimegepant, when taken every other day, was found to be effective as a preventive treatment of migraine, with its tolerability similar to placebo. It was proposed by the manufacturer that rimegepant is used for acute migraine treatment in patients who have failed to respond to two or more triptans.
The Checkup by Singlecare
MARCH 17, 2023
Food and Drug Administration approved Zavzpret, the first calcitonin gene-related peptide (CGRP) antagonist nasal spray to treat acute migraine (with or without aura) in adults. who experience migraine. Manufactured by Pfizer, Zavzpret (zavegepant) is a fas t-acting medication shown in Phase 3 clinical trials to have broad efficacy.
The Checkup by Singlecare
MARCH 8, 2024
Compare Aimovig alternatives | Beta blockers | Antidepressants | Anticonvulsants | Calcium channel blockers | Other CGRP receptor antagonists | Natural alternatives | How to switch meds Aimovig is an injectable drug approved to help prevent migraine headaches. Nausea, light sensitivity, and sound sensitivity typically accompany migraines.
Pharmacy Times
DECEMBER 7, 2023
Amanda Hickman, PharmD, MPH, MSCS, discusses the clinical assessment to lower migraines (CALM) in an HSSP setting.
Pharmafile
SEPTEMBER 5, 2023
AbbVie has announced that the Medicines and Healthcare products Regulatory Agency (MHRA) has granted a marketing authorisation for Aquipta (atogepant), for the prophylaxis of migraine in adult patients who have had at least four migraine days each month.
The Checkup by Singlecare
NOVEMBER 18, 2022
Before the first migraine-specific drugs hit the pharmaceutical market in 2018, the medications used to treat migraine were meant for other health conditions. Antidepressants, beta blockers, and epilepsy drugs reduced migraine symptoms in many people, but no one knew for sure how or why. Here’s what you need to know.
The Checkup by Singlecare
DECEMBER 11, 2023
Migraine headache Migraine headaches affect about 10% of the population. What distinguishes migraines from other types of headaches is that they tend to be a full-body experience: head pain and pressure are usually one of several symptoms. A tension headache is a primary headache that occurs without an underlying cause.
Pharmaceutical Technology
OCTOBER 4, 2022
A CGRP receptor antagonist, NURTEC ODT is approved by the US Food and Drug Administration (FDA) for use in adults for acute treatment of migraine irrespective of aura status as well as for preventive episodic migraine treatment. It is also approved in the EU under the trade name Vydura for use in similar indications.
Pharmaceutical Technology
MAY 19, 2023
The US Food and Drug Administration (FDA) has accepted Satsuma Pharmaceuticals’ 505(b)(2) new drug application (NDA) for STS101 for acute treatment of migraine, for review. It provides significant benefits compared to the current acute treatments for migraine.
The Checkup by Singlecare
JANUARY 2, 2024
“Dehydration headache most often has the appearance of a tension-type headache,” says Eric Baron, DO , a neurologist at the Cleveland Clinic Center for Neurological Restoration – Headache and Chronic Pain Medicine, in Cleveland. One thing that is clear: Dehydration makes headaches worse.
The Checkup by Singlecare
DECEMBER 27, 2023
Migraines can be debilitating, and they affect more than 1 billion people globally. Fioricet ( butalbital-APAP-caffeine ) is a combination medication used to treat tension headaches, but it may also be prescribed for migraines. How does Fioricet treat migraine headaches? Caffeine is a natural CNS stimulant that boosts alertness.
Pharmaceutical Technology
NOVEMBER 18, 2023
LuAG-09222 is under clinical development by H. Lundbeck and currently in Phase II for Migraine.
Pharmaceutical Technology
FEBRUARY 8, 2024
Prabotulinumtoxin A biosimilar is under clinical development by AEON Biopharma and currently in Phase II for Migraine.
Hospital Pharmacy Europe
DECEMBER 19, 2022
The presence of enlarged perivascular spaces in the brains of migraine patients may indicate the presence of glymphatic disruption. Migraine is a common headache-related condition that affects an estimated 12% of the population. Enlarged perivascular spaces in migraine and control patients.
The Checkup by Singlecare
DECEMBER 13, 2023
Headache behind eyes The most common types of headaches behind the eyes are cluster headaches, migraine headaches, and sinus headaches, according to Dr. Reddy. Cluster headaches and migraines tend to cause severe pain on just one side of your head, while sinus headaches can develop on one or both sides. Reddy and Natbony.
pharmaphorum
JANUARY 28, 2021
New findings from a digital study have challenged the belief that stress is a significant factor in triggering migraine attacks. At the same time 76% of the total number of migraine attacks were associated with either flat or decreasing levels of perceived stress.
The Checkup by Singlecare
DECEMBER 27, 2023
Common causes of a headache on top of the head include tension, nerve inflammation, migraine, and dehydration. Migraine headaches Migraine is a headache disorder that causes moderate to severe pain. For example, a headache on the top of the head often feels like a heavy weight or a tightness on or around the top of the skull.
Hospital Pharmacy Europe
MARCH 15, 2023
Zavegepant represents the first, non-oral calcitonin gene-related peptide receptor antagonist approved for the treatment of acute migraine In a press release, manufacturer Pfizer has announced that zavegepant has become the first calcitonin gene-related peptide receptor antagonist to receive approval by the FDA for the management of acute migraine.
Hospital Pharmacy Europe
NOVEMBER 1, 2022
Since 2006, he has been working on migraine and, in particular, experimental models of migraine. Professor Ashina’s research focuses on experimental models of migraine in humans. How would you define migraine and what are the main symptoms? How is migraine classified?
The Checkup by Singlecare
DECEMBER 27, 2023
In fact, a lack of sleep is a known trigger for migraine and other types of headaches, too. Research suggests that poor sleep quality directly affects the severity and frequency of migraine and tension headaches. This disruption can lead to certain types of headaches, including migraines and cluster headaches.
Pharmaceutical Technology
JULY 19, 2022
AbbVie has filed a Marketing Authorization Application (MAA) with the European Medicines Agency (EMA) for its atogepant for prophylaxis of migraine in adults who experience a minimum of four migraine days each month. An oral CGRP receptor antagonist (gepant), atogepant is developed as a preventive migraine treatment.
pharmaphorum
NOVEMBER 18, 2020
UK cost-effectiveness agency NICE has said that Eli Lilly’s Emgality can be made available through the NHS for migraine prevention, the second drug in the CGRP inhibitor class to achieve that milestone.
The Checkup by Singlecare
DECEMBER 26, 2023
Headaches on the right side of the head can be caused by muscle tension, migraine, sinus inflammation, and more. They can be remedied by over-the-counter (OTC) painkillers, prescription migraine medication, stretching, or hot or cold compresses. Typically, migraine causes throbbing pain on the left or right side of the head.
pharmaphorum
NOVEMBER 18, 2020
UK cost-effectiveness agency NICE has said that Eli Lilly’s Emgality can be made available through the NHS for migraine prevention, the second drug in the CGRP inhibitor class to achieve that milestone.
PharmaShots
JUNE 1, 2023
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Druggist
JANUARY 9, 2021
Migraine is a common condition affecting an estimated 6 million people in the UK. With approximate 190,000 migraine attacks experienced by people in the UK (NICE, 2012), pharmacies are among the first points of call to find over the counter migraine medication. What is the best painkiller for migraine? Paracetamol.
Hospital Pharmacy Europe
SEPTEMBER 8, 2022
Real-world observational study data presented at the Migraine Trust International Symposium (MTIS) demonstrate sustained effectiveness of Ajovy?(fremanezumab) fremanezumab) in reducing migraine attacks. . Fremanezumab is indicated for the prevention of migraine in adults with at least 4 migraine days per month.
The Checkup by Singlecare
DECEMBER 26, 2023
Eyebrow pain can be associated with various conditions, such as inflamed sinuses or migraine, among others. There are several possible conditions that may cause eyebrow headaches, such as sinusitis , migraine, glaucoma, and more. Migraine Migraine is very common, affecting over 37 million people in the United States.
pharmaphorum
JULY 18, 2022
AbbVie has submitted its oral CGRP inhibitor atogepant for prevention of both episodic and chronic migraine in the EU as it tries to catch up with main rivals Pfizer/BioHaven and their recently-approved Vydura drug. GlobalData has said it expects Qulipta to get approval for chronic migraine prevention in 2023, helping it to sales of $1.2
The Checkup by Singlecare
JANUARY 18, 2024
A heavy head may also be due to an illness or medical condition, like a sinus condition or migraine headache. Not sleeping enough —or even sleeping too much to make up for lost sleep—can cause migraines. Then, migraine pain can affect your sleep, causing a cycle of migraine headache pain and interrupted sleep.
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