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Roche cancer immunotherapy receives new EU approval

European Pharmaceutical Review

Compared with standard intravenous (IV) delivery, Roche stated that its monoclonal antibody biologic shortens treatment time by approximately 80 percent. The European Commission (EC) has approved the EU’s first PD-(L)1 cancer immunotherapy for subcutaneous injection.

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Roche subcutaneous cancer immunotherapy granted MHRA approval

European Pharmaceutical Review

The Medicines and Healthcare Products Regulatory Agency (MHRA) has authorised the first subcutaneous formulation of an anti-PD-(L)1 cancer immunotherapy to be made available to patients in Great Britain. The safety and efficacy profile was consistent with the IV formulation.

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Formulation Strategies for Large Molecule Drug Products

Impact Pharmaceutical Services

Large molecule drug products produce highly effective medicines, but formulation can be challenging because of their complexity, sensitivity, and potential for instability. It is crucial that formulation strategies ensure their bioavailability and efficacy to develop new and successful products.

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Nanoparticle Formulation: A Paradigm Shift towards Novel Drug Delivery

Roots Analysis

Owing to their unique size and physicochemical properties ( surface roughness, surface area, surface energy, crystal structure and shape ), nanoparticles can be widely used as a contrasting agent in medical imaging, a vesicle to cross the blood-brain barrier and a carrier for targeted delivery of genes / drugs, proteins, vaccines and antibiotics.

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A game of two halves for Roche’s recently approved wet AMD assets

Pharmaceutical Technology

Susvimo’s recall is due to a problem related to the seal on the port delivery device, which keeps the medicine from leaking out once it has been injected. For one, the need to insert this implant via a surgical route represents a resource-intensive procedure and is likely to limit its wider adoption in the market.

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Evaluating Your Journey to Achieving the Autonomous Pharmacy 

Omnicell

Furthermore, there are no standardized benchmarks available to guide pharmacy leaders in their quest to achieve improvements in areas such as safety, efficiency, regulatory compliance, financial performance, and human resource management. Nilesh Desai, MBA, BS, RPh, CPPS, Chief Pharmacy Officer of Baptist Health in Louisville, Ky.,

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Pharmaceutical Polymers / Medical Polymers -Current Scenario and Future Potential

Roots Analysis

Driven by the increasing need for safe and efficient medical devices and drug delivery systems, the pharmaceutical polymers / medical grade polymers domain is advancing significantly. There has been a rise in the development of polymers for biopharma with improved biocompatibility, biodegradability and functionality.