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Tackling immune-mediated disease with CAR Tregs

European Pharmaceutical Review

Recognising the potential of CAR T cells to act as highly targeted therapeutics, several biotechnology companies – including Sangamo Therapeutics – have established development pipelines of CAR T regulatory cells (Tregs) that aim to tackle immune?mediated What are Tregs and how are they applicable to immune-mediated disease?

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Not Just for Kids: The Case for Modernizing Immunization Registries

Fierce Healthcare

Not Just for Kids: The Case for Modernizing Immunization Registries. Wed, 12/07/2022 - 16:20.

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ASH: With immune thrombocytopenia win, argenx proves efgartigimod’s no one-trick pony in autoimmune disease

Fierce Pharma

ASH: With immune thrombocytopenia win, argenx proves efgartigimod’s no one-trick pony in autoimmune disease. Sat, 12/10/2022 - 09:12. fkansteiner.

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Health Experts’ Predictions for the 2022 Flu Season

BuzzRx

However, now that life is pretty much back to normal in 2022, things might be different. When someone recovers from infectious diseases like the flu or COVID-19, they retain some natural immunity that protects them from future infections. The COVID mitigation measures in 2020, therefore, led to less natural immunity.

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ESMO 2022: the evolution of TIL therapy – a highly promising approach

Pharmaceutical Technology

Before TIL infusion, the patient undergoes lymphodepletion, which reduces the proportion of myeloid immune suppressive cells and creates space for the incoming lymphocytes. The high level of neoantigens in melanoma makes this the ideal setting for TIL therapy, with tumours often containing multiple clones of tumour-reactive immune cells.

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4th Inflammasome Therapeutics Summit 2022

pharmaphorum

Marc Pelletier , Senior Principal Scientist – Translational Immune Oncology, Novartis. Kate Fitzgerald , Professor & Vice Chair, Department of Medicine, Division of Innate Immunity, University of Massachusetts Chan Medical School. The post 4th Inflammasome Therapeutics Summit 2022 appeared first on.

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COVID booster shots increase immunity, trial shows

pharmaphorum

A trial of booster vaccinations to protect against COVID-19 has shown that the jab significantly strengthens the body’s T-cell immunity against the disease. All of these boosted immunity in younger and older people with varying efficacy. The post COVID booster shots increase immunity, trial shows appeared first on.