Remove tag chemo
article thumbnail

STAT+: Bone marrow transplant advance could widen use of this less buzzy cure for sickle cell disease

STAT

These drugs have price tags of $2.2 This approach has been around for decades but required patients to have a well-matched donor and endure a hefty dose of chemotherapy, ruling out transplant as an option for the vast majority of patients. million and $3.1 million, respectively.

article thumbnail

FDA gives Daiichi Sankyo’s HER3 drug a breakthrough tag

pharmaphorum

After EGFR therapy fails, platinum-based chemo has limited efficacy, generally preventing disease progression or death for between four and six months. Daiichi Sankyo has now started a phase 2 trial – called HERTHENA-Lung01 – in 420 patients with EGFR-mutated NSCLC previously treated with at least one EGFR inhibitor and platinum-based chemo.

FDA 71
Insiders

Sign Up for our Newsletter

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Trending Sources

article thumbnail

Enhertu gets breakthrough tag in HER2-low breast cancer

pharmaphorum

The top-line results showed that Enhertu (trastuzumab deruxtecan) achieved a statistically significant and clinically meaningful improvement in both progression-free survival (PFS) and overall survival (OS) when compared to physicians’ choice of chemo.

article thumbnail

Gilead tags Merck for first-line triple negative breast cancer trial

pharmaphorum

Gilead is sponsoring the new study to see if adding Trodelvy can be an alternative chemo when added to Keytruda in the first-line treatment of advanced TNBC, in the hope of moving the ADC up the treatment pathway. The post Gilead tags Merck for first-line triple negative breast cancer trial appeared first on.

article thumbnail

Developing point-of-care CAR T manufacturing

European Pharmaceutical Review

Other examples include the absence of age requirement/limitation for CAR T-cell therapy and that chemo sensitivity is not mandatory for CAR treatment. This is in addition to its considerable price tag. 6-8 Clinical recommendations also change.