Sat.Jul 22, 2023 - Fri.Jul 28, 2023

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Pfizer's New Migraine Treatment Now Available in US Pharmacies: What You Need to Know

Drug Topics

Zavegepant (Zavzpret) is the first and only calcitonin gene-related peptide (CGRP) receptor antagonist nasal spray approved by the FDA for acute migraine treatment in adults.

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Study: Phenotype-Based Interventions Better for Obesity Than Calorie Restriction

Pharmacy Times

Phenotype-based interventions are individualized treatment plans that consider genetic and phenotypic characteristics instead of general restricted eating or exercise management.

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To detect breast cancer sooner, an MIT professor designs an ultrasound bra

STAT

Canan Dagdeviren has dedicated her career to creating tools that can capture data from every nook and cranny of the human body. An electrode that reads brain signals in Parkinson’s patients. A tattoo-like patch to detect skin cancer. And now, a bra containing a flexible ultrasound that could one day be used to more comfortably screen for breast cancer.

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Biogen, amid layoffs, ponies up $7.3B for rare disease specialist Reata and potential blockbuster Skyclarys

Fierce Pharma

On Monday during a quarterly earnings call, when Biogen CEO Chris Viehbacher was asked about the company’s potential to execute M&A, he randomly offered “we’ve got, I think, about $7.3 billion | Biogen has revealed a proposal to acquire Reata Pharmaceuticals for $7.3 billion. The Texas-based rare disease specialist brings newly approved Skyclarys, the first treatment for the neurologic disorder Friedreich’s ataxia with peak sales potential of $1.5 billion.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Senate Introduces Bipartisan Bill to Ensure Continued Access to Pharmacist Care, Services for Seniors

Drug Topics

The Equitable Community Access to Pharmacy Services legislation was introduced earlier this year in the House of Representatives.

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Twice-Yearly Subcutaneous Lenacapavir Injection for HIV Provides Favorable Quality-of-Life Outcomes

Pharmacy Times

Further analysis shows that 300 mg lenacapvir tablets plus an optimized background regimen can effectively reconcile a missed dose of lenacapavir injection in patients with HIV.

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AHA, BCBSA urge CMS to ditch 'conflicting' requirements in prior authorization reform proposal

Fierce Healthcare

Lobbying groups representing different camps of the healthcare industry have come together to urge the Centers for Medicare & Medicaid Service (CMS) to reconsider “conflicting regulatory propos | The American Hospital Association, American Medical Association and Blue Cross Blue Shield Association penned a joint letter highlighting "conflicting" prior authorization electronic standards and workflows they say will bring industry confusion and unnecessary burden.

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Women Treated for Breast Cancer Experience Accelerated Biological Aging

Drug Topics

Radiation therapy was associated with the largest increase, compared to chemotherapy or endocrine therapies.

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The Price of Avoiding Death at All Costs Is Steep

Pharmacy Times

Author of the book The Journey’s End discusses how extending life at all costs takes away time that patients could be spending with their families during the last moments of their life.

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How a Walgreens ambulatory care pharmacist is helping patients in Phoenix

Drug Store News

Walgreens ambulatory care pharmacist Mohanad Znbaqa and Village Medical primary care providers have collaborated to create a unique healthcare solution for patients in Phoenix.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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'The danger is great and growing': Healthcare experts call on industry to reduce the risks of nuclear war

Fierce Healthcare

The time is now 90 seconds to midnight, according to the Doomsday Clock, which scientists use to estimate how close humanity might be to blowing itself up with nuclear weapons. | The world hasn't been this close to nuclear war since the Cold War, say experts. Editors of prestigious medical journals sound a call to disarm.

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13 ways to raise your blood pressure

The Checkup by Singlecare

When your healthcare provider places the blood pressure cuff around your arm, you likely hope you won’t have high blood pressure. Hypertension is a common medical condition, but did you know there’s also a possibility your blood pressure could be too low? Turns out, a lot can be revealed as that cuff tightens around your biceps. Blood pressure is a measure of heart and vascular health, specifically the force of blood force flowing through blood vessels.

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Tirzepatide Demonstrates Significant Weight Loss Compared to Placebo

Pharmacy Times

A new study indicates that adults with obesity or who are overweight with weight-related comorbidities can help manage their weight with lifestyle changes in conjunction with specified treatment.

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Opinion: Doctors in states that ban abortion can still refer patients elsewhere. Why are so few doing that?

STAT

For now, abortion remains accessible even in states where it’s banned — at least for those who know where to look. It’s still legal in two-thirds of the country, and numerous websites explain how to order medications from international pharmacies to end early pregnancies at home. But not all patients have equal access to reliable information.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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How providers are navigating Florida's new law restricting access to gender-affirming care

Fierce Healthcare

Last month, the American Medical Association (AMA) passed a resolution to protect access to gender-affirming care, committing to opposing criminal and legal penalties against patients, their famili | Approved by Gov. Ron DeSantis, the law imposes restrictions on adult access to gender-affirming care. Some providers have been forced to stop serving new or existing patients in some capacity.

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Eli Lilly's tirzepatide aces 2 more late-stage obesity trials as FDA decision nears

Fierce Pharma

Eli Lilly continues to bolster the case for its dual GIP/GLP-1 agonist tirzepatide as a powerful weight loss agent. | Also known as Mounjaro in its approved type 2 diabetes indication, tirzepatide helped patients across two trials—Surmount-3 and Surmount-4—lose up to 26.6% of their body weight, Lilly said Thursday.

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Patients With Cancer Currently Have Lowest Risk of Severe COVID-19 Outcomes Since Start of the Pandemic

Pharmacy Times

Rates of hospitalizations and mortality from COVID-19 were more than 4 times lower in 2022 compared to 2021, as the virus become less severe with new mutations, a recent study found.

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Cases of alpha-gal syndrome caused by tick bites on the rise, CDC reports

STAT

For many Americans, the warmer spring and summer months bring backyard barbecues and scenic hikes — along with a chorus of cicadas, mosquitoes galore, and hypervigilant self-checks for ticks. Often, insect bites only cause mild discomfort but new reports from the Centers for Disease Control and Prevention warn that a food allergy caused by ticks is on the rise in the U.S.

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AWS rolls out generative AI service for healthcare documentation software

Fierce Healthcare

Amazon Web Services announced Wednesday a new AI-powered service for healthcare software providers that will help clinicians with paperwork. | AWS HealthScribe uses generative AI and speech recognition to help doctors transcribe and analyze their conversations with patients and drafts clinical notes.

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Roche's star eye drug Vabysmo crosses blockbuster threshold as rival stalls at FDA

Fierce Pharma

To Roche’s pharma chief Teresa Graham, no word better describes the company’s eye drug Vabysmo right now than “momentum.” | To Roche’s pharma chief Teresa Graham, no word better describes the company’s eye drug Vabysmo right now than “momentum.” Approved by the FDA in January 2022, Vabysmo already crossed the one-billion-dollar sales mark in the first half of 2023.

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Intravenous Immunoglobulin Effective Controlling Neuromuscular Disease in Patients with Cancer Treated with Immune Checkpoint Inhibitors

Pharmacy Times

It was previously undetermined whether the combination of IVIG and ICI would lead to patient complications or reduced efficacy of the cancer treatment, but 2 successful case reports dispel that belief.

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Mitch McConnell’s abrupt episode has an important public health takeaway

STAT

The handling of Senate Minority Leader Mitch McConnell’s abrupt medical issue this week is raising concerns among medical experts that the event sent a potentially dangerous public-health message — that when someone experiences an episode with symptoms like McConnell’s, they can simply return to work as though nothing had happened.

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AI, nurses protesting, another hospital shooting—Stakeholders debate how to make hospitals safe

Fierce Healthcare

This week, a visitor opened fire at Legacy Good Samaritan Medical Center in Portland, killing a security guard and injuring a nurse. | Following increases in both aggression towards nurses and mass shootings, stakeholders are debating whether new tech or old solutions can make a difference.

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Is Dramamine pregnancy-safe?

The Checkup by Singlecare

When you’re pregnant, you already have to deal with morning sickness, swollen feet, and hormonal changes—but you’re also more likely to get motion sickness. It doesn’t seem fair, does it? Fortunately, the drug Dramamine, which relieves motion sickness, can also help with morning sickness during early pregnancy —and is considered safe for pregnancy. Here’s what you should know about taking Dramamine while pregnant.

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Phase 3 Trial Underway for Novel Pembrolizumab Combination for Treatment of High-Risk Melanoma

Pharmacy Times

Pembrolizumab is already indicated to treat patients with unresectable or metastatic melanoma, along with stage 2B-3 melanoma after resection in adults and pediatric patients.

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Ending health disparities requires full federal government, National Academies panel says

STAT

To narrow the nation’s deeply entrenched health disparities, a permanent entity with regulatory powers should be created by the president to oversee health equity efforts across the entire federal government, says a report issued Thursday by the National Academies of Science, Engineering, and Medicine. In its many recommendations, the committee that wrote the report called for Congress to create a scorecard to assess how new federal legislation might affect health equity; urged all federa

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Medicare Advantage report shows enrollees capitalize on supplemental benefits

Fierce Healthcare

Most Medicare Advantage (MA) enrollees use one or more supplemental benefits, with most health plan members using multiple benefits, according to a newly released report from the Elevance Health Pu | Extra benefits from Medicare Advantage plans are highly utilized by enrollees, which improves health outcomes among at-risk populations, new analysis shows.

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Eli Lilly's Mounjaro shortage worsens ahead of potential obesity FDA approval

Fierce Pharma

As with Novo Nordisk’s popular offering for obesity, Wegovy, demand for Eli Lilly’s dual GIP/GLP-1 agonist Mounjaro appears to be outpacing supply once again. | The U.S. Food and Drug Administration has added a fourth dose of Lilly’s popular new diabetes med to its drug shortage database. The agency also expects supply issues with three other doses to persist longer than previously thought.

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Once-Weekly Insulin Analogue Demonstrates Promising Results for Those With Type 2 Diabetes

Pharmacy Times

Patients with type 2 diabetes receiving once-weekly insulin icodec were more likely to reach a hemoglobin A1C level below 7% compared to those who received once-daily insulin analogues.

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Asian American doctors, overrepresented in medicine, are largely left out of leadership

STAT

For 15 years, orthopedic surgeon Charles S. Day has been working to highlight the striking lack of diversity in his field, publishing studies showing orthopedics had the fewest Black, Hispanic, and female residents of any surgical specialty. Day himself is Asian American, a group that’s abundant in medicine. But as he dug further, his datasets and personal experiences began to collide.

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Blue Shield of California taps Microsoft's cloud tech to build integrated data hub

Fierce Healthcare

The need for speed underpins a collaborative effort by Blue Shield of California and Microsoft that will utilize the cloud to deliver data about members to the insurer and providers in real-time, t | Blue Shield of California is collaborating with Microsoft to move to its cloud platform to improve data collection, storage and analysis.

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Fierce Pharma Asia—Daiichi's leukemia nod; Astellas' protein degrader pact; Takeda's neuroscience setback

Fierce Pharma

Daiichi Sankyo's FLT3 inhibitor overcame FDA rejection to win an approval. Astellas signed another protein degrader deal, this time with PeptiDream. | Daiichi Sankyo's FLT3 inhibitor has overcome an FDA rejection to win an approval. Astellas signed another protein degrader deal. Takeda's enzyme replacement therapy flunked a mid-stage trial in a rare neurological disorder.

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Axatilimab Produces Significant Response in Patients with Fatal Post-Transplant Complication

Pharmacy Times

Co-developers Incyte and Syndax will submit a biologics license application to the FDA at the end of 2023 based on the results of a phase 2 trial among adult and pediatric patients with chronic graft-versus-host disease.

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Q&A with CDC Director Mandy Cohen: On communication, trust, and getting things done

STAT

The new director of the Centers for Disease Control and Prevention, Mandy Cohen, is only two weeks into her new job. But already she hears the clock ticking. If all goes well, Cohen — the successor to Rochelle Walensky, who stepped down at the end of June — will have about 18 months at the helm of the world’s premier public health agency before the next U.S. president is sworn in.