Sat.Aug 05, 2023 - Fri.Aug 11, 2023

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Here are 25 Medicare Part D drugs that have skyrocketed in price

Fierce Healthcare

Medicare Part D drug prices have increased by an average of 226% since market entry. These 25 drugs are responsible for $80.9 billion in total Part D spending in 2021. | A report from AARP broke down how popular brand-name drugs have continued to rise in price and exceed inflation.

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MorningRX: August 11, 2023

Drug Topics

HHS awards money to fight the nursing shortage, the FDA approves Johnson & Johnson's talquetamab-tgvs (TALVEY), and the CDC says suicides reached an all-time high in 2022.

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Significant Association Found Between Vitamin D, Improved Insulin Resistance

Pharmacy Times

Researchers say vitamin D supplementation could be a low-cost and effective avenue for the reduction of insulin resistance and better outcomes in preventing and treating diabetes.

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STAT+: More hospital pharmacists are rationing drugs due to increasing shortages

STAT

Nearly every hospital pharmacy across the U.S. is experiencing shortages of prescription drugs. And the problem has become so bad – especially for chemotherapies — that one-third of hospital pharmacists reported their institutions are rationing, delaying, or canceling treatments or procedures, according to a new survey. Specifically, 99% of hospitals pharmacists reported shortages, which is causing 85% to ration treatments and 84% to rely on different dosages.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Supreme Court blocks Purdue Pharma's bankruptcy settlement, threatening immunity to Sackler family

Fierce Pharma

It’s been a rough summer for pharmaceutical companies trying to resolve lawsuits by declaring bankruptcy. | The Supreme Court has halted Purdue Pharma’s $6-billion bankruptcy settlement, which granted the company’s former owners—the Sackler family—immunity from civil suits related to the opioid crisis.

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Long COVID Symptoms May Result in Cognitive Decline

Drug Topics

A study published in the Lancet found that patients who had previously tested positive for COVID-19 had lower cognitive accuracy compared to negative controls.

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Kim Kardashian sparks debate on the benefits of full-body MRI scans

STAT

The last time Kim Kardashian posted about medical imaging, it was to prove her butt was real. Now, she’s praising its ability to find aneurysms and cancers before they turn deadly. Kardashian’s Instagram post this week about Prenuvo, which sells full-body MRI scans that can run in the thousands of dollars, has renewed a long-running debate about whether the tests are actually valuable or just run the risk of clogging hospitals with false positives and unnecessary follow-ups from we

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Microsoft partners with Epic to roll out EHR cloud database solution, starting with Mount Sinai

Fierce Healthcare

Microsoft rolled out a new electronic health records cloud database solution, leveraging Azure Large Instances, that enables health systems to scale capacity for high-volume workloads. | Microsoft rolled out a new electronic health records cloud database solution, leveraging Azure Large Instances, that enables health systems to scale capacity for high-volume workloads.

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Zuranolone Approved as First, Only Oral Medication to Treat Postpartum Depression

Drug Topics

Approximately 1 in 8 women in the United States experience postpartum depression.

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Estrogen Impacts the Effects of Psilocybin for Women

Pharmacy Times

Jennifer Chesak, author of The Psilocybin Handbook for Women, discusses how estrogen can affect binding at the serotonin receptor sites, causing psilocybin to impact women’s bodies differently.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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Tuberculosis outbreak tied to bone grafts underscores shortcomings of testing

STAT

One person has died and at least four have been sickened by tuberculosis in infected bone materials, an outbreak that has cast a spotlight on the shortcomings of testing for such tissue products. It’s the second tuberculosis outbreak linked to the biomaterial device company, Aziyo Biologics. In 2021, Aziyo’s product killed eight people after orthopedic and dental surgeons unwittingly implanted infected bone grafts into patients.

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Bridging the Divide: Medical's Omnichannel Momentum

PharmExec

How pharma medical affairs and commercial teams are synchronizing their capabilities to boost omnichannel marketing strategies and better understand customer engagement needs.

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Welcome to San Diego: Things to Do at NACDS Total Store Expo

Drug Topics

After sessions end, head out to explore the city of San Diego.

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Expert Discusses Current Recommendations for Respiratory Syncytial Virus, Influenza, COVID-19 Vaccination

Pharmacy Times

Gretchen Garofoli, PharmD, an associate professor at the West Virginia School of Pharmacy, discusses the current recommendations for COVID-19, respiratory syncytial virus (RSV), and influenza vaccines and vaccine hesitancy.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Bird flu researchers turn to Finland’s mink farms, tracking a virus with pandemic potential

STAT

HELSINKI — It was the quiet that stood out to Tarja Sironen at the fur farm. A specialist in emerging infectious diseases, Sironen has conducted research at fur farms for years. She helped develop a Covid vaccine that was deployed to the country’s mink population during the pandemic. She knows the industry well.

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Amylyx's ALS drug Relyvrio gets off the ground as company eyes new brain disorder

Fierce Pharma

Amylyx Pharmaceuticals’ amyotrophic lateral sclerosis (ALS) drug Relyvrio continues to wow Wall Street. | Amylyx’s amyotrophic lateral sclerosis drug Relyvrio ​​​​​​​continues to wow Wall Street. The drug brought in $98.2 million revenue in the second quarter, handily beating analysts’ consensus estimates of below $92 million.

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7 ways to relieve diverticulitis pain fast

The Checkup by Singlecare

Pain management is essential to the treatment plan when someone is suffering. However, figuring out the right course of action for a particular condition can be difficult. There are many ways to worsen and prolong pain if not managed properly. People with diverticulitis often experience abdominal pain during or after eating a meal. Eating is a part of everyday life, so coping with a condition that is worsened by eating can be challenging.

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Significant Increase in Hospital Delirium, New Antipsychotic and Benzodiazepine Prescriptions Associated With COVID-19 Pandemic

Pharmacy Times

Unexpectedly, the highest increases in delirium compared to projections were in the 66 to 74 years of age group, which could have important personal and societal repercussions, such as earlier development of dementia.

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Opinion: Philanthropic endowments at universities can offer a way out of biotech’s Valley of Death

STAT

So many promising medical innovations never reach their full potential as therapies or cures, languishing instead in a metaphoric place many of us in biotech know as “the Valley of Death.” This valley represents the gap between when a scientist makes a discovery and when that work has reached the point when a pharmaceutical company will license it, or a venture capital firm will invest in it, to get it to the point to help the patients who need it.

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'Like a dairy farm treats cows': Henrietta Lacks' estate hits Ultragenyx with gene therapy vector lawsuit

Fierce Pharma

Less than a month after the family of Henrietta Lacks reached a settlement with Thermo Fisher over its use of Lacks’ cells, another drugmaker stands accused of profiting from a racist medical syste | Less than a month after the family of Henrietta Lacks reached a settlement with Thermo Fisher over its use of Lacks’ cells, another drugmaker stands accused of profiting from a racist medical system.

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Medicaid coverage for substance abuse treatment improved substantially since 2014: study

Fierce Healthcare

Access to care for Medicaid fee-for-service beneficiaries with substance use disorder has improved from 2014 until 2021, but much more can be done to improve it further, researchers say. | There have been substantial improvements in coverage for substance use disorder and opioid use disorder since 2014, according to a study in JAMA Network. Nonetheless, there’s room for yet more improvement.

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Driving Patient Safety With New Pharmacy HIT Standards

Pharmacy Times

New standards from the National Council for Prescription Drug Programs could drive changes that improve patient safety by optimizing drug therapy to reduce the risk of harm and improve health and well-being before a medication is dispensed.

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A Fierce Focus On Unmet Need

PharmExec

From public defender to spearheading the adoption of innovative drugs, Wendy Short Bartie, senior VP and general manager for the hematology and cell therapy division at Bristol Myers Squibb, has remained a steadfast patient advocate—working to fulfill unmet medical needs and bring treatments to as many people as possible.

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Propranolol for anxiety: Does it work?

The Checkup by Singlecare

Propranolol is an old drug that just won’t go away, for good reason. It touts a 50-year history of utility, originally as a treatment for heart disease and later as a preventive treatment for migraine, a use that has landed it on the World Health Organization’s list of essential medications. A role for propranolol that you may find more interesting is in the treatment of anxiety.

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Another round of layoffs hits BMS, with 100+ people impacted after earnings miss

Fierce Pharma

Bristol Myers Squibb has laid off more than 100 employees amid a reconfiguration of expenses that follows disappointing earnings results. | Bristol Myers Squibb has laid off more than 100 employees amid a reconfiguration of expenses that follows disappointing earnings results.

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Remibrutinib Shows Rapid Symptom Control in Chronic Spontaneous Urticaria

Pharmacy Times

Results of phase 3 trials could lead to the approval of remibrutinib to provide more effective and controlled treatment of chronic spontaneous urticaria than H1-antihistamines.

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STAT+: White House drug shortages task MIA with lawmakers while Congress works on fixes

STAT

WASHINGTON — A White House task force created to work on drug shortage reforms has yet to contact the lawmakers who are writing legislation to stem shortages — and it’s not clear when the task force will recommend policies. The White House formed a task force at the beginning of 2023 to deal with the issue of persistent drug shortages.

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Top Ten Tips for Taking the NBSTSA Surgical Technology Exam

Board Vitals - Pharmacist

The journey to becoming a certified surgical technologist is a noble one, filled with dedication, perseverance, and a commitment to excellence. At the heart of this journey lies a crucial milestone – the NBSTSA Surgical Technology Exam. This comprehensive exam contains 175 questions (150 graded) with a pass rate of just 73.7% in 2020. How can you best prepare for the CST exam ?

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'The Top Line': International Left-Hander's Day: How handedness impacts brain research

Fierce Pharma

In this episode of "The Top Line," Teresa Carey talks with Dr. | This week on "The Top Line," we discuss left-handedness and its significance in neurodevelopmental and psychiatric disorder research.

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Pre-Exposure Prophylaxis Continues to be Effective in Preventing HIV, Certain Populations Face Barriers

Pharmacy Times

Lack of information and access to health care, stigma, discrimination, criminalization, and privacy concerns are among the barriers some groups face when trying to obtain preventative HIV medications.

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STAT+: A yogurt drink instead of a colonoscopy? Study uses engineered bacteria to detect cancer

STAT

Dan Worthley, a gastroenterologist and cancer scientist at Colonoscopy Clinic in Brisbane, Australia, does thousands of colonoscopies a year, seeking and destroying precancerous polyps. It’s a practically surefire way to prevent colorectal cancer, but an unpleasant experience for patients. The future, Worthley hopes, will be much less onerous — and he’s developing a technology that, if it works one day, might make the experience more of a piece of cake.

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Charlie Health, Mantra Health to expand behavioral health care for higher ed students

Fierce Healthcare

Mantra Health, a digital mental health provider for higher education, is joining forces with adolescent-focused Charlie Health to broaden access for students seeking higher levels of care. | The partners will connect college and university students who require a higher level of mental health care to Charlie Health’s virtual intensive outpatient program.

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Pfizer faces whistleblower lawsuit from former compliance manager who says he flagged possible fraud in China

Fierce Pharma

After Pfizer allegedly fired a compliance manager for raising the flag on potential fraud activity in China, the former employee is hitting back. | Frank Han, Pfizer's former director of global compliance analytics, has filed a civil complaint against the drugmaker. Han claims he was terminated for identifying potential issues relating to the Foreign Corrupt Practices Act.

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Low Probability of 5% Weight Loss in Adults With Overweight or Obesity

Pharmacy Times

Despite the low uptake of healthy lifestyle behaviors to achieve 5% weight loss or greater, the probability of weight loss increased among individuals with higher initial BMI.

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