Sat.Jul 08, 2023 - Fri.Jul 14, 2023

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New report shows high-impact R&D happens after cancer medicines are first approved

PhRMA

A new report showcasing nine critical oncology treatments, highlights the vital role of post-approval research and development (R&D) in advancing cancer treatment options and delivering unprecedented progress in the fight against cancer over the past 10 years.

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Flu Vaccination Could Help Reduce Hospitalization for RSV

Drug Topics

A Western Australian study found the influenza vaccine has a possible protective effect against hospitalization for respiratory syncytial virus (RSV).

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Opinion: Why the aspartame in Diet Coke and Coke Zero probably isn’t worth worrying about

STAT

This essay was originally published on Gideon Meyerowitz-Katz’s Medium blog. A spartame is an artificial sweetener that is used in a lot of products, including Diet Coke and Coke Zero. Like most artificial sweeteners, we have a wonderful love/hate relationship with it. It’s sweet but doesn’t have any calories, so it’s great for people who want to lose a bit of weight.

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Moderna mounts 2 new patent lawsuits against mRNA rivals Pfizer, BioNTech: report

Fierce Pharma

Caught in a litigation crossfire, Moderna has reportedly opened two new fronts in its COVID-19 vaccine patent war with Pfizer and BioNTech. | Moderna has lodged two new lawsuits at the High Court in Dublin, Ireland, and the Brussels Commercial Court in Belgium, Juve Patent first reported. This adds to a complex web of ongoing mRNA patent litigation.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Key considerations as Congress works towards PAHPA reauthorization

PhRMA

This week, PhRMA submitted comments to the U.S. Senate Committee on Health, Education, Labor and Pensions (HELP) regarding the Pandemic and All-Hazards Preparedness Act (PAHPA) reauthorization draft. In our comments, we expressed our strong opposition to policy proposals that would inhibit the biopharmaceutical industry partnering with the government to address pressing public health needs.

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Utilizing AI for Medication Management

Drug Topics

Pharmacists can utilize AI for medication management and to prevent medication errors.

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More Trending

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Novo Nordisk's GLP-1 drugs under review in Europe after reports flag possible suicide risks

Fierce Pharma

Two cases of suicidal thoughts and one case of self-harm from users in Iceland of Novo Nordisk’s diabetes and obesity drugs have prompted the European Medicines Agency (EMA) to review the blockbust | Two cases of suicidal thoughts and one case of self-harm from users in Iceland of Novo Nordisk’s diabetes and obesity drugs have prompted the European Medicines Agency (EMA) to review the blockbuster products.

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The AI Revolution Has Arrived: Shaping the Next Generation of Pharma Marketing

PharmExec

Join five industry leaders as they unpack the transformative potential of artificial intelligence in the pharmaceutical industry, offering insights into real-world applications and the future of life sciences marketing in an era shaped by rapid technological evolution.

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Hospitals will recoup $9B under HHS' proposed remedy to 340B ruling

Fierce Healthcare

The federal government will pay eligible hospitals in the 340B program $9 billion to offset payment cuts the Supreme Court ruled unlawful last year. | The federal government will pay eligible hospitals in the 340B program $9 billion to offset payment cuts the Supreme Court ruled unlawful last year.

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Study: Eating 6 Key Healthy Foods Found to Lower Risk for Cardiovascular Disease

Pharmacy Times

Impact of healthy eating was especially evident in countries where consumption of these foods is low, which elevates the risk for cardiovascular disease, including heart attacks and strokes.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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Samsung Biologics, after expanding Pfizer collab, inks Novartis production deal worth $391M

Fierce Pharma

Just days after sewing up a pair of $897 million deals with Pfizer, Samsung Biologics has added a few hundred million dollars more to its partnership cash pile—this time courtesy of an expanded pac | Samsung Biologics said in a Monday regulatory filing that it’s inked a $390.9 million deal to help crank out Novartis drugs. The latest production pact builds on an earlier tie-up worth $81 million.

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Revealed: pharma giants pour millions of pounds into NHS to boost drug sales

The Guardian - Pharmaceutical Industry

Observer investigation raises concerns about the influence of drugs companies in shaping patient care in services that use their products Pharmaceutical giants are pouring tens of millions of pounds into struggling NHS services – including paying the salaries of medical staff and funding the redesign of patient treatment – as they seek to boost drug sales in the UK, the Observer can reveal.

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One year of 988: The crisis hotline's successes and challenges

Fierce Healthcare

The 988 Suicide & Crisis Lifeline added Spanish text and chat services ahead of the hotline’s one-year anniversary on Sunday. | The hotline transitioned to three digits last year. Since then, it has answered nearly 5 million calls, texts and chats.

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A Guide to Administering Influenza Vaccines in Special Populations: Focus on Patients Who Are Immunocompromised

Pharmacy Times

Expanding pharmacist–patient care services to include vaccine promotion and administration within ambulatory clinics is an example of the expanding role of pharmacists and their contribution to primary care practice.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Novartis pledges to appeal after Delaware court nixes patent on big-selling Entresto

Fierce Pharma

After a Delaware federal court ruled a Novartis combination patent on big-selling cardiovascular drug Entresto is invalid, the company pledged to continue its efforts to block generics with an appe | After a Delaware district court ruled a 2025 Entresto combination patent is invalid, Novartis will head to the U.S. Court of Appeals for the Federal Circuit in an effort to reverse the decision.

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FDA approves first ever OTC birth control pills

The Checkup by Singlecare

The U.S. Food and Drug Administration (FDA) approved the first over-the-counter birth control pill , Opill (norgestrel), on July 13. It’s the first time a nonprescription oral contraceptive will be available to consumers to prevent pregnancy. According to the FDA, there are 3 million unintended pregnancies in the U.S. each year, and the agency believes the wide availability of Opill will “reduce barriers” to accessing birth control.

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J&J expands global access to TB drug as popular novelist joins advocacy campaign

STAT

Advocates have been fighting Johnson & Johnson for years over a patent on a lifesaving tuberculosis pill. On Thursday, they won a partial victory as the United Nations-affiliated group STOP TB announced an agreement to make cheaper generics available across dozens of low- and middle-income countries with high rates of disease. The deal had been in the works for months and was signed in June, according to STOP TB global drug facility chief Brenda Waning.

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Study Aims to Improve PrEP Adherence for Those on Medication for Opioid Use Disorder With Cognitive Dysfunction

Pharmacy Times

Optimizing efforts to treat patients using medication for opioid use disorder with cognitive disfunction can improve PrEP treatment rates and reduce overall rates of HIV infection, a recent study indicates.

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WuXi Bio telegraphs spinoff of its bioconjugate subsidiary XDC

Fierce Pharma

Angling for greater independence, it appears the time has come for WuXi’s bioconjugation offspring to leave the nest. | WuXi Biologics has unveiled a proposed spinoff and separate listing of WuXi XDC Cayman—a joint venture between WuXi Bio and WuXi STA bred to tackle contract research, development and manufacturing of bioconjugates, including antibody-drug conjugates, antibodies and other biologic intermediates.

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Coalition of 12 Kaiser Permanente unions to picket 50 facilities amid contract negotiations

Fierce Healthcare

An 85,000-strong body of unionized healthcare workers is turning up the pressure on Kaiser Permanente as both sides hash out the terms of a new labor contract. | The demonstrations will involve "tens of thousands" of union participants seeking increased staffing commitments in their next labor contract.

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Is it safe to mix ibuprofen and caffeine?

The Checkup by Singlecare

Most people can’t go without their daily dose of caffeine—a brain and nervous system stimulant that increases energy levels and alertness. Studies suggest that about 85% of Americans consume caffeine every day. Although coffee is the majority of people’s go-to, other sources of caffeine include tea, soda, chocolate, and energy drinks. But, if you take ibuprofen for pain relief, you may wonder whether you can still have your daily dose of caffeine.

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How Comprehensive Medication Management Improves Patient Outcomes, Health Equity

Pharmacy Times

When a patient is engaged in the home by a team that includes a pharmacist resource, social determinants of health issues become more clear and the care team can help close the gaps.

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Celiac study examines precisely how gluten triggers injury to intestine

STAT

For a person with celiac disease, eating a bagel goes something like this: chewing and savoring, the flavor of the high-gluten bread made ever more delicious by its forbidden nature, by knowing there will be hell to pay.  Then, the bagel is broken down, separated into the digestible and the not: Parts of gliadin, a protein found in gluten, stay in the gut.

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UnitedHealth kicks off Q2 earnings with $5.5B in profit, double-digit revenue growth

Fierce Healthcare

Healthcare giant UnitedHealth Group kicked off insurer earnings for the second quarter Friday morning, when it reported $5.5 billion in profit alongside double-digit revenue growth. | Healthcare giant UnitedHealth Group kicked off insurer earnings for the second quarter Friday morning, when it reported $5.5 billion in profit alongside double-digit revenue growth.

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Can you get pneumonia in the summer?

The Checkup by Singlecare

Most of us have suffered through a summer cold or two at some point. No big deal, right? But most people didn’t give much thought to more serious illnesses during the summer… until COVID-19 came along. Now, many people wonder if they might be at risk for contracting other serious illnesses in the summer, too. One illness that many people don’t associate with summer, but you still can catch, is pneumonia.

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Monoclonal Antibodies as Pre-exposure Prophylaxis May Be Cost-Effective Approach to Reduce Severe Outcomes in COVID-19

Pharmacy Times

Pre-exposure prophylaxis of neutralizing SARS-CoV-2 monoclonal antibodies may be preventative against SARS-CoV-2 transmission, decreasing frequency of new infections and number of hospitalized patients who need antiviral therapies, thus lowering costs.

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In talc defense, Johnson & Johnson sues 4 doctors over their 'junk litigation opinions'

Fierce Pharma

As Johnson & Johnson awaits a decision on its second attempt to resolve talc lawsuits through a bankruptcy ploy, the company is attempting another legal tactic to free itself from those liabili | As Johnson & Johnson awaits a decision on its second attempt to resolve talc lawsuits through a bankruptcy ploy, the company is attempting another legal tactic to help free itself from those liabilities—suing doctors who say that its iconic baby powder can cause cancer.

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Pharma Not the Only Ones Upset with PBM Practices

Pharmaceutical Commerce

The National Alliance of Healthcare Purchaser Coalitions releases resources for employers/health plan purchasers to offer insights on PBMs role in high prescription drug costs.

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As value-based health moves from philosophy to reality, providers, payers focus on equity and interoperability

Fierce Healthcare

Equity was at the forefront of Reuters’ value-based health conference in Philadelphia last month. | Over two days, executives from accountable care organizations, health systems and payers spoke about interoperability, population health, social determinants, the cost of care and taking on risk.

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Missed or Delayed Pediatric Preventative Care During COVID-19 Pandemic Influenced By Race, Enabling Factors

Pharmacy Times

Study among the first to examine delayed or missed pediatric preventative care during COVID-19 that considers determinants, race, and ethnic group, according to the authors.

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ICER updates cost-effectiveness threshold for bluebird, Vertex and CRISPR's dueling sickle cell gene therapies

Fierce Pharma

The potentially curative promise of gene therapies often carries a steep price tag. | The potentially curative promise of gene therapies often carries a steep price tag. But for a pair of personalized medicine prospects in sickle cell disease (SCD), the cost could be worth it, at least as far as ICER is concerned.

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FDA approves first over-the-counter birth control pill

STAT

In a highly anticipated move, the Food and Drug Administration on Thursday approved the first over-the-counter birth control pill , a decision that could transform the way contraception is delivered in the United States. For the first time, people will now be able to readily purchase birth control online and at pharmacies, convenience stores, and grocery stores without a prescription, a requirement that has been seen as a hurdle to greater access to contraception.

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Medicare Advantage overpayments continue to balloon. Here are ways policymakers could address the problem

Fierce Healthcare

When Paul Ginsburg, Ph.D., Steve Lieberman and other experts co-authored | While insurers would likely fight massive changes to the program, experts say less drastic updates could still go a long way toward lowering overpayments.

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FDA Accepts New Drug Application for Zanubrutinib Combination for R/R Follicular Lymphoma

Pharmacy Times

Zanubrutinib combined with obinutuzumab was previously granted both Fast Track and Orphan drug designations for patients with relapsed or refractory follicular lymphoma.

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