Mon.Dec 04, 2023

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Instagram Could Serve as Educational Platform for New FDA Drug Approvals

Drug Topics

An evaluative study on an open resource Instagram page that provides information on new medications to pharmacists was recently presented at the American Society of Health-System Pharmacists 2023 Midyear Clinical Meeting and Exhibition.

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Migraine Medication Could Be More Effective Than Ibuprofen for Treatment of Attacks

Pharmacy Times

Three classes of drugs could be 2 to 5 times more effective than ibuprofen for the treatment of migraine attacks, according to results of a study.

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Sweeping bill to fight opioid addiction will be considered by Senate health committee

STAT

The Senate health care committee will consider a sweeping bill next week meant to combat the opioid epidemic, according to four lobbyists and a congressional aide familiar with the legislation.  The proposal would reauthorize a number of programs first created by the SUPPORT Act, an addiction-focused bill that Congress first passed in 2018. Many of those programs’ authorizations expired earlier this year, however, leading addiction treatment advocates to fret that lawmakers —

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Reduced Structural Stigma Against Sexual Minorities Is Associated With Greater Rates of Male PrEP Prescriptions

Pharmacy Times

The study authors note that additional policies to reduce structural stigma against sexual minorities could continue to improve the rate of individuals who initiate PrEP use.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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STAT+: How sickle cell became the first disease treated by CRISPR

STAT

Nearly a decade ago, consultants delivered to Rodger Novak a kind of Sears catalog of human malady: 200 pages, listing dozens of different diseases, each annotated with — from a business standpoint — their best and worst attributes.  The document was supposed to help Novak, then the chief executive of CRISPR Therapeutics, navigate a pressing quandary.

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Liposomal Bupivacaine Reduced Opioid Consumption Following Cesarean Section, Poster Says

Drug Topics

A poster from ASHP Midyear 2023 demonstrated the effectiveness of liposomal bupivacaine as it is used for cesarean section procedures, regarded as an area with increasing utilization.

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More Trending

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Navigating the Oncology Specialty Patient Journey

Drug Topics

In this conversation from HAS 2023, Randy Falkenrath demystifies the oncology medication management model and explains how specialty pharmacist can help patients access care.

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STAT+: Official: FDA needs staff influx to meet gene therapy needs

STAT

WASHINGTON — The Food and Drug Administration needs dozens more reviewers if it wants its so-called Operation Warp Speed for rare disease therapies to take off, the agency’s biologics chief said Monday. The administration launched the rare disease pilot program, dubbed START and modeled after the record race for a Covid-19 vaccine, this September.

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FDA Approves Pirtobrutinib For Treatment of Adult Patients With CLL, SLL

Pharmacy Times

Pirtobrutinib is the first and only non-covalent BTK inhibitor to be approved by the FDA and is indicated for adult patients who already received at least 2 prior lines of therapy.

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Opinion: A well-meaning FDA policy is a threat to pediatric cancer treatment

STAT

The medical community today faces a deceptively simple question: How quickly should we act when a child’s life is on the line? I’m a pediatric oncologist, so my answer won’t surprise you — I think we should act immediately. But a new Food and Drug Administration policy could delay things for children who need treatment now.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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Medicare Part D Claims Have Increased, But 340B Prescriptions Increased Faster

Pharmacy Times

The proportion of prescriptions by a 340B-affiliated physician increased from 9.4% in 2013 to 19.3% in 2020, but the prescriptions filled by 340B pharmacies increased from 18.4% to 49.9%.

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Maia Oncology picks up $4.25M to build out virtual primary care clinic for cancer patients

Fierce Healthcare

Five years ago, Liya Shuster-Bier entered cancer as an otherwise healthy 29-year-old. | Maia Oncology raised $4.25 million in seed funding to hone its go-to-market strategy, hire more talent and launch its first pilot in partnership with a cancer center and health insurance company.

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Stress Ulcer Prophylaxis May Not Prevent Gastrointestinal Bleeding in Neonates

Drug Topics

According to a poster presented at the American Society of Health-System Pharmacists Midyear Clinical Meeting & Exhibition, stress ulcer prophylaxis (SUP) did not increase adverse effects, suggesting limited preventive benefits for gastrointestinal bleeding (GIB) in neonates.

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Northwell, NYC Children's Services, foster agencies team up to help young adults transition from foster care

Fierce Healthcare

Northwell Health has teamed up with New York City organizations to launch a new pilot program that aims to improve healthcare services for young adults transitioning out of foster care. | Working with the Administration for Children's Services and the Center for Fair Futures’ coaches, the program will enroll 50 to 100 transition-age adults, pairing them with Northwell’s patient navigation services.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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High-flying Fujifilm splashes $200M to beef up cell therapy capacity

Fierce Pharma

Fujifilm Corporation is spreading the wealth across two production units as the contract development and manufacturing organization (CDMO) juggernaut works through a cell therapy expansion. | Fujifilm is dividing $200 million between a pair of subsidiaries. Those are: Fujifilm Cellular Dynamics, which specializes in development and manufacturing of human induced pluripotent stem cells (iPSC), and the organization’s CDMO for biologics and advanced therapies, Fujifilm Diosynth Biotechnologies.

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Roche makes obesity play with $2.7bn deal to buy Carmot

pharmaphorum

Roche has agreed a deal to acquire US biotech Carmot Therapeutics that if consummated will thrust it into the increasingly competitive market for incretin-based therapies for diabetes and obesity. The Swiss pharma group has agreed to pay $2.7 billion upfront in cash when the deal closes, with shareholders in the US company also in line for up to $400 million if the drug programmes covered by the agreement meet various milestones.

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Contract manufacturing giant WuXi's stock plummets as it warns of $400M revenue miss

Fierce Pharma

A challenging year for the biotech industry has taken a heavy toll on Chinese manufacturer WuXi Biologics, sending the company’s stock plummeting nearly 24% Monday. | WuXi Biologics expects to miss its original sales target for the year by around $400 million, thanks to reductions across its development and manufacturing services. WuXi blamed the projected miss largely on a COVID-related revenue slowdown and a decline in projects.

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Slideshow: Evaluating Perioperative Opioid Use and Analgesic Options

Drug Topics

Three poster presented at the ASHP Midyear Clinical Meeting delved deeper into perioperative pain management.

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STAT Morning Rounds: Six health news stories you need to start your day

STAT

Understand how science, health policy, and medicine shape the world everyday. Sign up for our Morning Rounds newsletter here. How sickle cell became the first CRISPR’d disease Nearly a decade ago, consultants delivered to Rodger Novak a kind of Sears catalog of human malady: 200 pages, listing dozens of different diseases, each annotated with — from a business standpoint — their best and worst attributes.

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Study: Substantial Deficiencies in Capture of Cognitive Safety in Drug Trials

Pharmacy Times

Despite nearly one-third of reversible dementia cases being drug induced, cognitive safety is a neglected aspect of clinical trials.

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Capturing the modern male shopper

Drug Store News

Listen to DSN's "Capturing the Modern Male Shopper" webinar, which includes insights from Spotify, Reddit and Hawthorne to examine the next big trends, deep dive on marketing crossovers and more.

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Joint Commission's new voluntary certification helps hospitals ensure 'responsible' use of patient data

Fierce Healthcare

The Joint Commission is launching a voluntary certification program for hospitals and critical access hospitals to demonstrate their responsible use of patient’s health data for non-clinical purpos | The accreditation giant wants its Responsible Use of Health Data Certification program to serve as an objective evaluation of whether a hospital is following best practices around secondary use of data.

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Novel Technology Could Reduce Weight Control Drug Injections for Patients With Diabetes

Pharmacy Times

A new hydrogel drug delivery system could change the way diabetes is managed.

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Blue Shield of California discloses data breach, number of members impacted unclear

Fierce Healthcare

Data on Blue Shield of California members may have been exposed due to a vulnerability in the MOVEit file transfer platform. | Data on Blue Shield of California members may have been exposed due to a vulnerability in the MOVEit file transfer platform.

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Certain Personality Traits May Lower the Risk of Developing Dementia

Pharmacy Times

Although personality was linked to cognitive performance on tests, it was not linked to dementia pathophysiology.

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STAT+: Pharmalittle: Roche to buy obesity-drug developer for $2.7 billion; Novo Nordisk paid U.S. doctors $26 million over a decade

STAT

Good morning, everyone, and welcome to another working week. We hope the weekend respite was relaxing and refreshing, because that oh-so familiar routine of online meetings, phone calls, and deadlines has predictably returned. But you knew this would happen, yes? After all, the world, such as it is, somehow keeps spinning. So time to nudge it in a better direction with a fresh cup of stimulation.

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See the 10 most popular health articles of 2023

The Checkup by Singlecare

Coming off the COVID-19 pandemic, 2023 was a much more normal year of health news. Jimmy Kimmel made jokes about Ozempic at the Oscars, artificial intelligence (AI) saw its early implementation in healthcare, and researchers made sweeping innovations in the treatment of harmful diseases. It was a year of innovation, but also a year of prescription drug shortages and price hikes.

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I reversed my type 2 diabetes. Here’s how I did it | Neil Barsky

The Guardian - Pharmaceutical Industry

Modern medicine makes it seem as if drugs are the only way to deal with diabetes. But what if diet can be a solution? One gray Sunday in the middle of the Covid lockdown, I received an unwelcome call from my family doctor. Until then, for virtually my entire life, I had managed to stay out of a doctor’s office, except for routine checkups. My luck had run out.

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The top 10 most-asked questions about SingleCare

The Checkup by Singlecare

You may have heard about SingleCare from your pharmacist or through a television commercial. It’s likely you know that SingleCare can help you save up to 80% on prescription costs—but you may not know all about the free prescription savings card. For instance, did you know you can use our card even if you have insurance, Medicaid, or Medicare? It’s true!

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New Jersey's RWJUH, nurses' union strike tentative deal to end contentious 4-month strike

Fierce Healthcare

New Jersey’s largest academic medical center has reached a tentative agreement with a union representing about 1,700 of its nurses to end a four-month strike. | The labor dispute over pay and staffing held about 1,700 nurses without pay or benefits and drew the attention of top U.S. health policy legislators.

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Supreme Court wrestles with OxyContin maker’s bankruptcy deal

STAT

WASHINGTON — The Supreme Court on Monday wrestled with a nationwide settlement with OxyContin maker Purdue Pharma that would shield members of the Sackler family who own the company from civil lawsuits over the toll of opioids. The justices seemed by turns relucant to break up an exhaustively negotiated agreement, but also leery of somehow rewarding the Sacklers.

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CVS Health rebrands healthcare services business as it plots long-term growth strategy

Fierce Healthcare

After spending nearly $20 billion to pick up Signify Health and Oak Street Health this year, CVS rebranded its health services business to "CVS Healthspire" as it plots its long-term growth strateg | After spending nearly $20 billion to pick up Signify Health and Oak Street Health this year, CVS rebranded its health services business to "CVS Healthspire" as it plots its long-term growth strategy.

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STAT+: FDA efforts to oversee foreign drug manufacturing remain inadequate to ensure safety, analysis finds

STAT

In the wake of the Covid-19 pandemic, the Food and Drug Administration inspected far fewer domestic and foreign pharmaceutical facilities, even though manufacturing activity did not decline, according to a new analysis. Meanwhile, FDA budgeting and staffing held steady, although resources allocated for each inspection surged and more plants were cited for serious violations.

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Novel generalised myasthenia gravis treatment approved

European Pharmaceutical Review

The European Commission (EC ) has authorised ZILBRYSQ ® (zilucoplan)▼ as the first once-daily subcutaneous (SC), targeted peptide inhibitor of complement component 5 (C5) inhibitor for generalised myasthenia gravis ( gMG ). It is also the only C5 inhibitor approved for self-administration by adult patients who are AChR antibody-positive with this disease.

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