Wed.Jul 19, 2023

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Monthly Buprenorphine Initiation Rates Remain Flat, Despite Policy Changes

Drug Topics

Only 1 in 5 patients who initiated buprenorphine were retained in therapy for at least 180 days.

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Recommended Flu Vaccines for Older Adults

Pharmacy Times

An expert panel examines the distinctions among the 3 primary recommended flu vaccines for individuals aged 65 and above, assessing their efficacy compared with standard-dose flu vaccines.

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Genetic cheat code might explain why some people catch Covid but never get sick

STAT

In the earliest days of the Covid-19 pandemic, when the new coronavirus still appeared to be confined to China, public health authorities were divided over whether to declare the outbreak a global emergency. That changed once it became clear that the virus was silently spreading farther and faster than anyone realized — fueled by transmission among contagious people who didn’t feel sick.

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Confirmatory PAPILLON Study Supports Amivantamab-vmjw For Patients with Severe Lung Cancer Mutation

Pharmacy Times

The 5-year survival rate for patients with exon 20 insertion EFGR mutation is 8% in the frontline setting, worse than the survival rate of the 2 most common types of EGFR mutations in patients with advanced or metastatic non-small cell lung cancer.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Stanford president to resign after investigation finds he failed to ‘decisively and forthrightly’ correct research

STAT

In an abrupt turn, Stanford president and renowned neuroscientist Marc Tessier-Lavigne announced Wednesday that he will step down as the university’s leader. His resignation came after he learned the results of an extensive investigation into his past research, which confirmed data-manipulation in scientific papers that he co-authored and found that he took insufficient steps to correct them.

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Correlation Between Vaccines and Flu Transmissions

Pharmacy Times

Adam C. Welch, PharmD, MBA, FAPhA, evaluates the impact of yearly flu vaccinations on curtailing the spread of influenza among communities and populations.

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More Trending

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Double-Blind Trial Shows Low-Cost Subcutaneous Version of Ketamine Is Effective Over Placebo in Treating Treatment-Resistant Depression

Pharmacy Times

Generic ketamine could cost as little as $5, which is significantly lower than the $800 per dose for the currently available S-ketamine nasal spray.

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Obesity drug shortage expands to Saxenda as Novo Nordisk warns of limited supply for 2023 and beyond

Fierce Pharma

After Novo Nordisk's popular obesity medicine Wegovy went into short supply, people turned to the company first-generation weight-loss drug, Saxenda, for treatment. | After Novo Nordisk's Wegovy became hard to come by, people turned to the company first-generation weight loss drug, Saxenda, for treatment. Now, the company is struggling to handle demand for that product.

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Event-Free Survival Improved by Radiotherapy for B-Cell Lymphoma in Younger Patients

Pharmacy Times

Due to the assessment of computerized tomography with criteria from 1999, the role of radiotherapy in patients with diffuse large B-cell lymphoma with bulky or extranodal disease remains undefined.

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Cancer drug shortages deliver ‘gut punch’ to patients unsure if their survival odds will be undercut

STAT

Mairéad McInerney will never know if changes in her treatment plan have undercut her odds of surviving stage 3 triple-negative breast cancer. Critical shortages in cancer drugs have forced her to change course not once, but twice. The first time, her physicians flipped the order of her drug regimen because Taxol (paclitaxel), one of two drugs she was supposed to take, was not available, said McInerney, who was diagnosed in December 2022.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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Rollout of Long-Acting Cabotegravir Without Delay Can Have Greatest Impact on HIV PrEP

Pharmacy Times

Investigators said pre-exposure prophylaxis rollout is efficient in settings with high HIV incidence, but not in settings with low HIV incidence.

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The kidney, in all its complexity, is captured in an atlas that could aid disease research

STAT

The kidneys are some of the most architecturally complex organs in the human body — intricate in a way that becomes frustrating when, for millions of people each year, they lose function.  It’s only in recent decades that scientists have been able to leverage new techniques, like the ever-growing list of “-omics,” to peer deep inside human cells.

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Increasing Social Support for Young Adults With HIV Could Improve Viral Suppression

Pharmacy Times

Patients with perinatally-acquired HIV reported low emotional, instrumental, and friendship support at 37%, 32%, and 36%, respectively.

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TikTok cracks down on users posting about popular weight loss drugs

STAT

As the demand for GLP-1 based drugs grows, content about the new class of weight loss drugs on TikTok has fueled the flames of its popularity. Now, the social media platform has taken action against many of the users who post frequently about the medications. Dozens of accounts were suspended from TikTok in early July, many belonging to content creators who talk about their weight loss and monetize the platform via partnerships with telehealth companies that prescribe GLP-1s and other weight los

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Supporting the Evolving Retail Pharmacy Landscape While Improving Medication Adherence

Pharmacy Times

Mobile apps can help consumers acquire medications, but few help with adherence beyond automatic refills or medication synchronization.

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STAT+: To get better heart data from wearables, researchers train AI to separate the signal from the noise

STAT

As wearable health devices grow more popular in the U.S., there’s a growing opportunity to track the broader adult population’s heart health. But it’s much harder for an Apple Watch to accurately detect the heart’s electrical signals and rhythm than a set of hospital-grade electrodes. Its readings are messier, often because of poor contact with the skin.

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Study Confirms Race, Exposure Risk Play Significant Roles in Who Contracts COVID-19

Pharmacy Times

The findings could help in future vaccine prioritization strategies and therapeutic allocation policies for other pandemic.

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STAT+: Stanford president’s departure begs the question: Who takes the credit — or blame — in team science?

STAT

The resignation of Marc Tessier-Lavigne as president of Stanford University following an investigation into irregularities in his past research marks more than just the startling downfall of the leader of one of the nation’s top research powerhouses. The case is likely to have broader repercussions, signaling a tipping point in an ongoing and often contentious debate about how to assign blame and credit in the increasingly collaborative world of research.

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Engaging Communities through High-Impact Healthcare Sponsorships in the Pharmaceutical Industry 

Pharma Marketing Network

Sponsorships can be a powerful tool for pharmaceutical companies to engage with communities and make a positive impact on health and wellness. When done right, sponsorships can help pharmaceutical companies connect with their target audience, build relationships with key stakeholders, and promote their brand in a meaningful way. Here are some examples of how pharmaceutical companies can use sponsorships to engage communities: Sponsoring community health events: Pharmaceutical companies can s

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STAT+: App developer Twill hunts for pharma partner to market its digital depression treatment

STAT

In another sign of the business headwinds facing prescription mental health apps, developer Twill will shop around for a pharmaceutical company to market Aspiro, its cognitive behavioral therapy treatment for both generalized anxiety and major depression. Twill executives told STAT the company hopes that a drugmaker developing or currently marketing a product for generalized anxiety, or GAD, and major depressive disorder, or MDD, will be interested in adding a digital therapeutic to boost the ef

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GSK-funded report on adult vaccination rates ?finds major global declines in recent years

Fierce Pharma

While vaccines for COVID-19 have certainly enjoyed the spotlight in recent years, rates of uptake for other shots have sharply declined. | The GSK-funded report looked at adult vaccination data and found a major slump in vaccine adoption over the last few years, save for COVID vaccines.

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STAT+: House committee probes FDA inspections of pharma plants in China and India

STAT

A congressional committee is demanding the U.S. Food and Drug Administration provide detailed information about pharmaceutical plant inspections in China and India, two countries whose significant production of generic drugs and active pharmaceutical ingredients has caused concern about an overreliance on foreign manufacturers. Chinese and Indian manufacturers receive the largest number of warning letters about quality control issues from the FDA, including carcinogens in medicines, destroyed or

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Argenx raises $1.1B through global stock placement after Vyvgart's CIDP trial win

Fierce Pharma

Right on the heels of a major study win for its star drug Vyvgart, argenx has raised more than $1 billion in cash to support its operations. | Right on the heels of a major study win for its star drug Vyvgart, argenx has raised more than $1 billion in cash to support its operations.

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STAT+: A new explanation for why some stubborn cancer cells resist treatment

STAT

Cancer drugs can burn through tumors like a wildfire, killing off the vast majority of malignant cells. But a few stubborn cells often end up surviving, seeding a recurrence of the disease. The prevailing theory behind this drug resistance is built on natural selection: Among the vast and genetically diverse population of cancer cells in a tumor, some have random mutations that help these cells survive an onslaught.

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Content Marketing as a Sales Driver: Unlocking Your Business Potential in the Pharmaceutical Industry

Pharma Marketing Network

Content Marketing as a Sales Driver: Unlocking Your Business Potential in the Pharmaceutical Industry Content marketing is a long-term strategy that can help businesses of all sizes generate leads, increase brand awareness, and drive sales. By creating and distributing valuable content, businesses can attract and engage their target audience, position themselves as experts in their field, and build trust with potential customers.

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Opinion: Listen: Dance helped this nurse heal from trauma. Now she’s bringing it to others

STAT

“Y ou can’t pour from an empty cup” is what registered nurse Tara Rynders learned the hard way after two decades of work and one heartbreaking, life-threatening experience of being a critical care patient herself. Before that experience, she’d always found found that dance, play, and other types of movement helped her express and heal from the trauma she encountered and held in her body every day.

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Creating Synergy: Aligning Brand Values with High-Impact Healthcare Sponsorships in the Pharmaceutical Industry 

Pharma Marketing Network

Sponsorships can be a powerful way for businesses to connect with their target audience, build relationships with key stakeholders, and promote their brand in a meaningful way. But in order to be truly effective, sponsorships must be aligned with a company’s brand values. For pharmaceutical companies, this means aligning sponsorships with causes that are related to health and wellness.

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FTC, DOJ propose new changes to guidelines for reviewing anticompetitive mergers

Fierce Healthcare

The Federal Trade Commission (FTC) and the Department of Justice (DOJ) released a draft update to merger guidelines, which they use to determine merger and acquisition deals’ compliance with antitr | The federal regulators said their draft guidelines better reflect the market realities of the "modern economy." The update includes a tighter focus on platforms, labor and market concentration when reviewing a potential merger deal.

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Efficacy of novel drug proven in MDD study

European Pharmaceutical Review

Phase II study results for navacaprant (NMRA-140), a novel kappa opioid receptor (KOR) antagonist for major depressive disorder (MDD) demonstrated significant and clinically meaningful improvement in depression for participants. The data “are compelling, particularly the significant improvements observed in both depressive and anhedonic symptoms,” stated Dr Roger S McIntyre, FRCPC, Professor of psychiatry and pharmacology, University of Toronto and Executive Director of the Brain and Cogni

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Choosing the Right Sponsorships for Maximum Impact in the Pharmaceutical Industry 

Pharma Marketing Network

Sponsorships can be a powerful tool for pharmaceutical companies to engage with their target audience, build relationships with key stakeholders, and promote their brand in a meaningful way. But with so many different healthcare organizations and causes to choose from, it can be difficult to know where to start. Here are some tips for choosing the right sponsorships for maximum impact in the pharmaceutical industry: Start with your goals: What do you hope to achieve through your sponsorship?

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J&J ordered to pay mesothelioma patient $18.8M in talc case, pledges to appeal

Fierce Pharma

Amid a nationwide freeze on Johnson & Johnson’s talc litigation, one case that had been allowed to proceed has ended in a trial verdict in favor of the plaintiff. | Johnson & Johnson says it will appeal a California jury's ruling in favor of a 24-year-old mesothelioma patient based on “erroneous rulings” by the trial judge, vice president of litigation Erik Haas said in a statement.

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Digital Disruption in Pharma: Harnessing Technology for Effective Marketing Campaigns 

Pharma Marketing Network

The pharmaceutical industry is constantly evolving, and digital technology is playing an increasingly important role in marketing campaigns. In the past, pharmaceutical companies relied heavily on traditional marketing methods such as print ads, TV commercials, and direct mail. However, these methods are becoming less effective as consumers are increasingly turning to digital channels for information and research.

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STAT+: States increasingly look to regulate hospital facility fees

STAT

Unexpected “facility fees” charged by hospitals have become a growing source of rage for patients, and more states are taking steps to rein them in. A new report, published by Georgetown University’s Center on Health Insurance Reforms and West Health, examined 11 states that regulate facility fees and conducted interviews with numerous government officials, patient advocates, health insurers, hospitals, and billing experts.

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Avoid Errors by Checking Patients’ Medications Lists

Pharmacy Times

Inaccurate information, miscommunication during transition points can have dire consequences.

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