Mon.Aug 14, 2023

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Illinois Governor Signs Legislation Targeting PBM Retaliation

Drug Topics

Illinois Governor JB Pritzker signed into a law a bill prohibiting PBM retaliation against pharmacists who disclose information during government proceedings.

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Study Finds Sugar-Sweetened, Artificially Sweetened Beverages Associated With Risk of Liver Cancer, Chronic Liver Disease Mortality

Pharmacy Times

Study authors note that additional research is necessary to confirm findings and identify biological pathways of associations between sweetened beverages and diseases of the liver.

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Expert Interview: Exploring the Full Capabilities of Generative AI

Drug Topics

Generative AI is the fastest growing technology ever, and is anticipated to be adopted faster than the world wide web.

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FDA Approves New Combination Therapy for BRCA-Positive Metastatic Castration-Resistant Prostate Cancer

Pharmacy Times

Niraparib and abiraterone acetate (Akeega; Janssen Pharmaceutical Companies of Johnson & Johnson) is the first-and-only dual action tablet that combines a PARP inhibitor with abiraterone acetate administered with prednisone.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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CVS Health Foundation awards $6.6M in grants to improve maternal health outcomes

Drug Store News

CVS Health is awarding $6.6 million in grants to Massachusetts General Hospital, the American Heart Association and March of Dimes to remove barriers to maternal health services.

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FDA Grants Accelerated Approval to Elranatamab-bcmm for Relapsed or Refractory Multiple Myeloma

Pharmacy Times

Elranatamab-bcmm (Elrexfio; Pfizer) is a BCMA-CD3-targeted bispecific antibody approved for adults with relapsed or refractory multiple myeloma who were previously administered at least 4 lines of therapy that included a proteasome inhibitor, an immunomodulatory agent, and an anti-CD38 monoclonal antibody.

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Expert Panel Discusses Community Solutions to Advance Food is Medicine Programs

Pharmacy Times

Session at NACDS Total Store Expo discusses how pharmacies can leverage their accessibility to decrease diet-related diseases through health and wellness.

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Pfizer attempts to ward off generic competition to pricey heart med Vyndamax with patent lawsuit

Fierce Pharma

Just four years into the rollout of Pfizer's pricey heart medication Vyndamax, the company is already playing patent defense against a potential copycat. | Along with the Scripps Research Institute, the drug giant claims the proposed copycat would step on a Pfizer patent and two Scripps patents.

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Look-Alike Packaging, Drug Shortages Continue to Contribute to Medication Errors

Pharmacy Times

Because the generic name of both the timolol once-daily and twice-daily formulations is the same, pharmacies should only carry 1 formulation.

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Opinion: I’m a dentist. I’m begging people not to give up on aspartame

STAT

The International Agency for Research on Cancer (IARC, an entity within the World Health Organization) recently announced that aspartame, a sugar substitute used in about 6,000 products worldwide, is “possibly carcinogenic to humans.” If this sounds familiar, it’s because reports of this assessment have circulated for two weeks, after anonymous sources leaked it to the press.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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Study Finds Myasthenia Gravis Not Caused by Vitamin D Deficiency, Counter to Prior Research

Pharmacy Times

Previous studies were not able to establish whether the risk of developing myasthenia gravis was caused by or led to vitamin D deficiency.

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STAT+: Hospitals are dialing back on venture capital investing

STAT

Hospitals once dove headfirst into venture capital with splashy headlines and attention-grabbing numbers. Now, in an era of flattened margins and exceedingly uncertain returns, many health systems are quietly pulling back. NewYork-Presbyterian’s venture firm, once managing roughly $40 million in assets, was essentially dissolved, two former employees said, with leaders punting it from the system’s strategy division to innovation, then from innovation to the investment office ȁ

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Weight Loss, Alzheimer Drugs Are Top of Mind for the 2023/24 Market

Pharmacy Times

Expert weighs in on the growth of specialty drug spending, particularly with drugs in immunology, neurology, and weight loss.

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STAT+: What’s behind the recent surge in Apellis’ stock price? Growing confidence in the safety of its eye treatment

STAT

Shares of Apellis Pharmaceuticals are rebounding, driven by a growing belief among some investors that the serious safety issue that has derailed Syfovre, the company’s eye disease treatment, is receding. Declaring the crisis over is premature, but that could change with more uneventful weeks. Apellis has been a takeout target before, and may be again, at an acquisition price nearly twice its current market value.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Thermo Fisher lays off 200-plus at clinical-stage cell and gene therapy factory in Florida

Fierce Pharma

As layoffs continue to roil the biotech industry, bigger drugmakers and manufacturers such as Bristol Myers Sq | As layoffs continue to roil the biotech industry, bigger drugmakers and manufacturers like Bristol Myers Squibb and Emergent BioSolutions haven’t been immune. Now, Thermo Fisher Scientific is among the latest to plot hundreds of job cuts.

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Listen: How Long Island became the ‘eugenics capital of the world’

STAT

The study of eugenics wasn’t born on Long Island — it’s closer to say it went through puberty there. The idea of eugenics — a pseudoscience that promoted the idea that certain people or groups should be removed from the human gene pool — originated in England with Francis Galton, a cousin of Charles Darwin. Galton took the emerging ideas of evolution and genetics and attempted to apply them to human society.

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Amazon Pharmacy's latest move aims to ease access to affordable insulin

Fierce Healthcare

Amazon has been focused on ways to make prescription drugs more affordable for consumers as it works to carve out a piece of the retail pharmacy market. | Amazon Pharmacy will automatically apply drug manufacturer-sponsored coupons on more than 15 insulin and diabetes care brands during online check-out. With the coupons, many insulin brands are available to eligible customers starting at $35 a month with free delivery.

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STAT+: Not-for-profit CommonSpirit Health paid its CEO $35 million in 2021

STAT

CommonSpirit Health, the massive not-for-profit health system formed through a 2019 merger, paid its former CEO $35.5 million in 2021, the latest year for which data is available.  The size of Lloyd Dean’s pay package is likely to reignite questions about health system CEO pay, especially at tax-exempt organizations. It’s more than twice the total compensation paid to the CEO of Ascension, a comparably sized not-for-profit system, and puts him in the upper tier of many for-pro

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Structured Agendas for Productive Hospital Leadership Meetings with Free Sample

indispensable health

Introduction In the fast-paced and intricate world of healthcare, seamless coordination between various departments is crucial to ensure quality patient care and effective administration. One pivotal collaboration exists between the hospital president or administrator and the director of the pharmacy. To maximize the efficiency and effectiveness of their routine interactions, a well-structured agenda is essential.

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STAT+: After Optum Health’s lowest profit margin in a decade, UnitedHealth makes changes

STAT

Just weeks after the division of UnitedHealth Group that provides care to patients posted its lowest profit margin in a decade, the company has shuffled around several top executives. Amar Desai is now CEO of Optum Health, according to a July LinkedIn post. Optum Health encompasses UnitedHealth’s physician practices, surgery centers, urgent care clinics, and other providers.

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8 drugs to avoid with diverticulitis

The Checkup by Singlecare

Diseases affecting the colon and GI tract can be excruciating and uncomfortable. Diverticulitis is a condition that can disrupt someone’s life with mild to severe symptoms. When in pain, people want relief quickly—which is why they may seek help from a medical professional. Healthcare providers can prescribe several treatments for diverticulitis, including prescription and over-the-counter medications.

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STAT+: In the case of a devastating disease, the FDA weighs an experimental drug’s muddled data and a desperate need

STAT

Emma Albee knows the experimental drug she takes is not a cure. It won’t allow her to stop using the wheelchair she’s relied on since adolescence, and it’s not going to take away the latticework of bone that has locked her hips in place. But for Albee and the roughly 1,000 people with a rare genetic disorder that causes their body to grow rigid bone where it doesn’t belong, the drug symbolizes a future in which years of research, advocacy, and tireless fundraising mig

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Kevyn Aucoin’s Signature Sculpting Sticks simplify contouring

Drug Store News

The Signature Sculpting Sticks collection features products with a creamy and blendable formula that helps users define their own features with light, contrast and color, the brand said.

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Chasing AstraZeneca and Pfizer, Johnson & Johnson snags FDA nod for prostate cancer combo Akeega

Fierce Pharma

Following FDA approvals for fellow PAPR inhibitors made by AstraZeneca/Merck and Pfizer, Johnson & Johnson has got its own combo approval in prostate cancer. | Following FDA approvals for fellow PAPR inhibitors made by AstraZeneca/Merck and Pfizer, Johnson & Johnson has got its own combo approval in prostate cancer. The tablet treatment, known commercially as Akeega, combines J&J’s Zytiga and niraparib.

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Chemotherapy prescribing habits for stage 3 colon cancer changed following IDEA study

Hospital Pharmacy Europe

A significant and increasing trend towards the use of a three-month rather than six-month adjuvant chemotherapy regime in stage 3 colon cancer has been observed following publications from the IDEA collaboration abstract. The use of a six-month regimen of FOLFOX (fluorouracil, leucovorin, and oxaliplatin) or CAPOX (capecitabine and oxaliplatin) became the standard adjuvant therapy in stage 3 disease from 2004 when trials convincingly showed that the addition of oxaliplatin improved overall survi

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Revance pivots into therapeutics with cervical dystonia nod for Botox rival Daxxify

Fierce Pharma

After debuting in the aesthetics market with Daxxify last year, Revance has made its way to the potentially lucrative therapeutic space. | Daxxify snagged its first therapeutic indication with Monday's FDA nod to treat cervical dystonia in adults. The green light comes a little less than a year after the Revance injection’s initial approval for temporary improvement of glabellar lines, or frown lines.

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Intranasal epinephrine shows clinical advantage over autoinjector for anaphylaxis

Hospital Pharmacy Europe

An intranasal epinephrine formulation leads to faster absorption of the drug than from an Epipen autoinjector, providing a clinical advantage in the short therapeutic window for the treatment of anaphylaxis, the manufacturer Nasus Pharma has announced. Positive results from a clinical study of the investigational powder-based epinephrine, FMXIN002, were published in the Journal of Allergy and Clinical Immunology in Practice.

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Lilly completes biopharma acquisitions

European Pharmaceutical Review

Eli Lilly and Company has completed acquisition of two biopharmaceutical companies – Versanis Bio and Sigilon Therapeutics – and their lead assets focused on obesity and diabetes. Lilly announced the successful completion of its acquisition of clinical-stage Versanis Bio and its lead asset bimagrumab, an anti-obesity medicine. Under the terms of the deal – first announced in July – Versanis shareholders could receive up to $1.925 billion in cash, inclusive of the upfront payment and subs

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Mishmash of how U.S. heat deaths are counted complicates efforts to keep people safe as Earth warms

STAT

PHOENIX — Postal worker Eugene Gates Jr. was delivering mail in the suffocating Dallas heat this summer when he collapsed in a homeowner’s yard and was taken to a hospital, where he died. Carla Gates said she’s sure heat was a factor in her 66-year-old husband’s death, even though she’s still waiting for the autopsy report.

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Chutes & Ladders—Cleveland Clinic hires first chief analytics officer; Express Scripts exec to work with independent pharmacies

Fierce Healthcare

Chutes & Ladders—Cleveland Clinic hires first chief analytics officer; Express Scripts exec to work with independent pharmacies ntong Mon, 08/14/2023 - 10:37

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STAT+: Pharmalittle: White House drug-shortage panel is MIA with lawmakers; Ultragenyx sued by Lacks family

STAT

Good morning, everyone, and welcome to another working week. We hope the weekend respite was relaxing and invigorating, because that oh-so familiar routine of online meetings, phone calls, and deadlines has predictably returned, even if this is the dog days of summer. So to cope, yes, we are firing up the coffee kettle and reaching for another cup of delicious stimulation.

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HebeCell and Logomix partner to develop PSC-NK cells

Pharmaceutical Technology

HebeCell has forged a strategic collaboration with Logomix for researching and developing gene-edited natural killer cells (NK cells).

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Three of the top 10 patient safety concerns directly involve medication management!

OctariusRx

Three of the top 10 patient safety concerns directly involve medication management, according to the annual report from the Emergency Care Research Institute (ECRI). Other concerns, such as staffing shortages can indirectly impact medication management and lead to patient harm. Who is responsible for medication management at your facility? What steps are you taking to enhance patient safety and reduce your liability?

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Riding the mRNA wave, HDT Bio closes in on cancer-fighting vaccine

PharmaVoice

The company believes its platform could deliver safer and more efficient mRNA options for cancer and infectious diseases.