Wed.Jun 28, 2023

article thumbnail

Why Artificial Intelligence is Critical to the Success of Value-Based Care

Drug Topics

Employing AI-driven technology ensures accurate and timely compliance with industry regulations, mitigates audits and fines, and helps forecast accurate reimbursements.

187
187
article thumbnail

p-Cresol Inhibitors Point to New Therapeutics for Treatment of Clostridioides difficile

Pharmacy Times

Investigators identified potential ways to inhibit the HpdBCA decarboxylase, which can reduce the production of p-cresol and make CDI more susceptible to bacteria in the gut microbiome.

123
123
Insiders

Sign Up for our Newsletter

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Trending Sources

article thumbnail

Assessing Medicaid Policy Barriers to Gene, Cell Therapies

Drug Topics

Researchers of a new paper discuss the inconsistencies between gene and cell therapy indications and payor coverage.

187
187
article thumbnail

Illegal Online Pharmacies Are Putting Patients at Risk

Pharmacy Times

The growing volume of drugs sold through illegal online pharmacies are estimated to generate 10 times higher adverse event rates than drugs sold through legal pharmacies.

123
123
article thumbnail

Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

article thumbnail

FTC floats changes to merger review process that could slow down deal-approval timelines

Fierce Healthcare

Newly proposed changes to the Federal Trade Commission’s pre-merger notification requirements would give regulators more information to review during a deal’s initial waiting period—likely giving t | The federal regulator said its proposed updates would enable more efficient review of pending deals during the initial 30-day waiting period. As is, the changes are estimated to add, on average, more than 100 hours to companies' paperwork burden per filing.

126
126
article thumbnail

Gates Foundation to fund trial of long-awaited new tuberculosis vaccine candidate

STAT

The Gates Foundation unveiled plans Wednesday to fund a long-awaited trial for what, if proven effective, would be the first new tuberculosis vaccine in over a century. The 26,000-person, Phase 3 study, set to begin next year, will test a vaccine known as M72/AS01 that showed promising results from a smaller trial in 2019. The findings stoked excitement at the time.

Vaccines 125

More Trending

article thumbnail

Congress Members Urge Biden to Address Prior Authorizations in Medicare Advantage

Drug Topics

A bipartisan group of 61 U.S. senators and 233 members of the U.S. House of Representatives signed onto a joint letter asking the Centers for Medicare & Medicaid Services to approve reforms.

98
article thumbnail

Study: Vitamin D Exposure May Increase Development of Dopamine Neurons, Indicating Mechanism of Schizophrenia

Pharmacy Times

Evidence shows vitamin D deficiency is linked to abnormal dopamine signaling disorders in neurodevelopment, including schizophrenia.

132
132
article thumbnail

Headspace partners with Virgin Pulse to build out digital mental health services for employers, health plans

Fierce Healthcare

Companies continue to ramp up investments in resources to support employees' mental health and wellbeing as workers grapple with work-related stress, burnout, depression and anxiety. | Digital mental health company Headspace is building on its partnership with Virgin Pulse to make it easier for employers and health plans to provide a range of mental health resources to their employees and plan members.

117
117
article thumbnail

Mifepristone Has its Day in Court

Pharmacy Times

As the battle over abortion rages, mifepristone has become the new center of the legal fight between anti-abortion advocates and the FDA.

FDA 123
article thumbnail

What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

article thumbnail

Menopause care is still a largely untapped market. Here's why investors and startups should dive in

Fierce Healthcare

Menopause is having its moment. High-profile investments and startups with celebrity names attached have brought long-overdue attention to this once-taboo area of women's health. | Menopause is having its moment. High-profile investments and startups with celebrity names attached have brought long-overdue attention to this once-taboo area of women's health.

115
115
article thumbnail

Independent Community Pharmacies Stepped Up With COVID-19 Response

Pharmacy Times

During the pandemic, many community pharmacists also gained the authority to provide routine vaccinations for child populations.

article thumbnail

UnitedHealthcare to waive cost-sharing in 24/7 Virtual Visit program for some fully insured plans

Fierce Healthcare

UnitedHealthcare will nix out-of-pocket costs for its 24/7 Virtual Visits in some of its fully insured plans beginning July 1. | UnitedHealthcare will nix out-of-pocket costs for its 24/7 Virtual Visits in some of its fully insured plans beginning July 1.

Insurance 114
article thumbnail

When young people survive cancer, their mental-health struggles are often just beginning

STAT

Thanks to advances in treatments, children’s chances of surviving cancer are higher than ever before. But the trauma that patients experience as they deal with the disease can pose a lifelong risk to their mental health, according to a recent analysis published in JAMA Pediatrics. The meta-analysis of 52 clinical studies measured the prevalence and severity of psychological disorders in over 20,000 young cancer survivors.

108
108
article thumbnail

5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

article thumbnail

Calm Health working with Mayo Clinic to develop cancer-specific mental health program

Fierce Healthcare

Calm Health, the mental health offering of meditation app Calm, is tapping the Mayo Clinic to help design digital mental health programs to help cancer patients manage anxiety, depression and menta | The upcoming digital mental health program will be available to Calm Health customers and “will be designed for all adults with cancer,” according to the announcement.

article thumbnail

AstraZeneca sows $400M investment in push to plant 200M trees by 2030

Fierce Pharma

Eco-minded AstraZeneca speaks for the trees. | AstraZeneca—often on the frontlines of environmental stewardship—is expanding its AZ Forest program to the tune of $400 million. With that new investment, the company is raising its commitment to plant and nurture 200 million trees across six continents by 2030—the same year AstraZeneca aims to halve its environmental footprint across its entire value chain.

105
105
article thumbnail

Mark Cuban Cost Plus Drugs teams with Posterity Health on male fertility

Fierce Healthcare

Mark Cuban Cost Plus Drug Company has announced its latest move, with the firm stepping into the male fertility space in partnership with Posterity Health. | Mark Cuban Cost Plus Drug Company has announced its latest move, with the firm stepping into the male fertility space in partnership with Posterity Health.

110
110
article thumbnail

Opinion: It’s past time to address the problem of indoor air quality. A new technology can help

STAT

Until the early 20th century, America regularly experienced brutally destructive urban fires. Conflagrations like the 1871 Great Chicago Fire, which destroyed more than 17,000 buildings and left 100,000 people homeless, were thought to be unfortunate but inevitable: Large numbers of buildings in close proximity naturally led to large fires. But then, conscious changes to the built environment eliminated large urban fires.

105
105
article thumbnail

Joint Commission unveils voluntary health equity certification, strengthens existing standard

Fierce Healthcare

The Joint Commission is kicking off a new advanced, voluntary certification for hospitals with processes in place to address healthcare disparities and promote equity among staff, the accreditation | Effective July 1, hospitals and critical access hospitals will be able to apply for an optional certification distinguishing those that make equity a strategic priority, the accreditation organization said.

Hospitals 109
article thumbnail

With approval supplement on deck, Reata dives into launch of its first commercial product Skyclarys

Fierce Pharma

With a spring approval in hand, Reata Pharmaceuticals has been waiting patiently to launch its first commercial product, Skyclarys. | After an FDA thumbs up on Reata's approval supplement for Skyclarys, analysts feel confident the newly commercial-stage company can meet—or potentially even exceed—a $45.9 million sales target for 2023.

FDA 104
article thumbnail

Author Health launches with $115M to care for seniors with serious mental illnesses, substance abuse disorders

Fierce Healthcare

Author Health banked $115 million for its new platform offering care and treatment for Medicare Advantage members with serious mental illness and substance use disorders. | Author Health banks $115 million for its new platform offering care and treatment for Medicare Advantage members with serious mental illness and substance use disorders. Humana will be the first to launch the startup’s services in conjunction with CenterWell Senior Primary Care in South Florida.

107
107
article thumbnail

Modulating Levels of miR 204-5p Could Become a Therapeutic Approach for Melanoma

Pharmacy Times

The microRNA member miR-204-5p inhibits apoptosis in melanoma cells treated with dacarbazine or when overexpressed.

123
123
article thumbnail

STAT+: ‘It’s like Groundhog Day’: The cancer drug shortage isn’t new — and neither are the solutions

STAT

A young girl, maybe 5 or 6 years old, had come into Yoram Unguru’s clinic with acute lymphoblastic leukemia, the most common of all childhood cancers. One of the drugs needed for treatment was methotrexate. The only problem was that the drug was in short supply. “Oftentimes we can cure kids of their disease, but we can’t do that without the drugs,” said Unguru, a pediatric hematologist oncologist at Children’s Hospital at Sinai in Baltimore and the Johns Hopkin

article thumbnail

Eton Pharma hit with FDA rejection for methanol poison treatment as regulator flags manufacturing concerns

Fierce Pharma

Eton Pharmaceuticals’ dehydrated alcohol injection didn’t pass muster with the FDA, instead receiving a complete response letter (CRL) raising flags the company believes are “addressable.” | The dehydrated alcohol injection was turned down due to problems with its chemistry manufacturing and controls, issues which the company believes are addressable, it said in a statement.

FDA 98
article thumbnail

Opinion: Listen: Cancer drug shortages should be causing more outrage

STAT

Drug shortages are a growing problem in the U.S., and a shortage of livesaving cancer drugs in particular has reached crisis levels. On the latest episode of the “First Opinion Podcast,” oncologist Kristen Rice explains that drug shortages have been happening for several years but have been progressively worsening in the past few months.

100
100
article thumbnail

AbbVie, Genmab's Epkinly shows promise in follicular lymphoma. Will FDA get on board?

Fierce Pharma

Merely a month into an FDA approval, AbbVie and Genmab’s bispecific drug Epkinly has chalked up a positive readout that might enable an expansion in blood cancer, although the exact regulatory path | Merely a month into an FDA approval, AbbVie and Genmab’s bispecific drug Epkinly has chalked up a positive readout that might enable an expansion in blood cancer, although the exact regulatory path remains unclear.

FDA 98
article thumbnail

STAT+: Moonlake’s less-than-transparent data disclosures produced a cash windfall. Risks remain

STAT

For two days starting on Sunday, Moonlake Immunotherapeutics happily crunched numbers and shared results from a mid-stage clinical trial that depicted its experimental antibody in the most flattering terms possible. The drug, called sonelokimab, was “changing the game” for the treatment of a debilitating skin condition called hidradenitis suppurativa, or HS, said Moonlake CEO Jorge Santos da Silva, on a call for investors and analysts.

98
article thumbnail

Metronidazole for dogs: What you need to know

The Checkup by Singlecare

Man’s best friend is really the perfect name for our sweet little pooches. We love them so much and would basically do anything to make sure our dogs are happy and healthy. So when our dogs get sick and can’t tell us what’s wrong, we rush them to the vet and go with whatever they prescribe. If your vet has recently prescribed your canine metronidazole and you’d like to learn more about it, we’ve gone to the veterinary medicine experts to find out everything you need to know.

Dosage 98
article thumbnail

Opinion: Smoke from Canadian wildfires shows outdoor workers need air quality protections

STAT

In 20 states, people are once again breathing in hazardous smoke from Canadian wildfires. The return of the air quality warnings, just weeks after the first took much of the U.S. by surprise, are a reminder that we will keep experiencing these conditions in the absence of integrated and health-driven climate adaptation policies. As global temperatures continue to rise, we are likely to see more periods of extreme and prolonged heat as well as reduced rainfall and humidity, which in turn increase

96
article thumbnail

Pfizer's approval streak continues with FDA blessing for growth hormone treatment Ngenla

Fierce Pharma

Pfizer is on an FDA heater. | Pfizer is on an FDA heater. With a blessing Wednesday for once-weekly growth hormone deficiency (GHD) drug Ngenla, the New York pharma giant has racked up four approvals from the agency over the last five weeks.

FDA 96
article thumbnail

A replacement for race: Medical experts explore how to eliminate bias in clinical algorithms

STAT

WASHINGTON — Most of the medical community has acknowledged that racism is baked into many of its clinical tools: pulse oximeters and kidney function calculators are prime examples. But as presentations at a conference Tuesday showed, physicians remain divided on when to remove race from calculators and algorithms — and crucially, what characteristics should replace it.

article thumbnail

Peggy Noonan to speak at 2023 NACDS Total Store Expo

Drug Store News

Peggy Noonan, renowned columnist, author, political analyst and former presidential speechwriter will lead a timely conversation on culture, politics and current events.

96
article thumbnail

STAT+: Pharmalittle: FDA declines to approve higher dose version of Regeneron eye drug; FDA warns wholesaler over counterfeit HIV pills

STAT

Good morning, everyone, and how are you today? We are doing just fine, thank you. Given that this is already the middle of the week and we have survived this far, no reason not to continue, yes? Just consider the alternatives. In fact, this modest accomplishment calls for celebration. So please join us in quaffing a ritual cup of needed stimulation.

FDA 93
article thumbnail

DIA 2023: Courtney Granville Discusses Issues Impacting Broader Supply Chains

Pharmaceutical Commerce

In an interview with Pharma Commerce Editor, Nicholas Saraceno, Courtney Granville, Director, Scientific Affairs, Drug Information Association, discusses issues impacting broader supply chains.

92