Thu.Aug 31, 2023

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Revolutionizing Drug Development Through Artificial Intelligence, Machine Learning

Pharmacy Times

The seamless integration of artificial intelligence and machine learning has the potential to accelerate research and enhance efficiency in a new era of personalized medicine.

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Don’t Get Caught Up With a HIPAA Violation

Drug Topics

Sometimes, breaches in information are the result of a simple mistake. How can those be avoided?

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Trending Sources

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Ferric Carboxymaltose Therapy Does Not Significantly Improve Heart Failure Mortality

Pharmacy Times

Ferric carboxymaltose was not found to have a significant impact on 6-minute walk distance, which is part of the primary outcome’s hierarchical composite of death and hospitalizations from heart failure.

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Cardiovascular Care Inequities Lead to Worse Outcomes for Women With Atrial Fibrillation

Drug Topics

A recent study found that women were less likely to get LDL-C testing and be treated with statins, despite having higher levels of LDL-C and higher blood pressure than men.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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No longer brushed off: A Minnesota clinic tries to rewrite medicine’s approach to miscarriage

STAT

WOODBURY, Minn. — By the time Taylor Teske came to be sitting on an exam table in an obstetrician’s office in Minnesota, her medical records marked a devastating journey: nine pregnancies, one baby, eight miscarriages. The first miscarriage happened in June 2018, almost as soon as she found out she was pregnant. Teske told her boss at the vascular clinic where she worked that she was pregnant, and he asked if she wanted to sneak a look using the clinic’s ultrasound.

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Info blocking enforcement for health IT entities begins Sept. 1, brings fines of up to $1M per violation

Fierce Healthcare

Enforcement of information blocking penalties for health IT entities is slated to go into effect on Friday, opening the door to penalties of up to $1 million per violation. | The Department of Health and Human Services Office of Inspector General said it expects to receive more complaints than it can investigate and so will be prioritizing those meeting certain criteria.

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More Trending

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Study: More Sleep Could Lessen Impulsive Behavior in Children

Pharmacy Times

When children got less than the recommended 9 hours of sleep or took more than 30 minutes to fall asleep, there was a strong link to impulsive behaviors later in life.

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STAT+: Departing Stanford president retracts two widely cited papers, against lead author’s wishes

STAT

After an expansive investigation found manipulated data and other issues with papers co-authored by Stanford’s now ex-president Marc Tessier-Lavigne , the prominent neuroscientist on Thursday retracted two studies published in the journal Science in 2001 — over the objection of a former postdoctoral researcher who played a leading role in both projects.

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Researchers Confirm Positive Outcomes With SSRI Treatment for Postnatal Depression

Pharmacy Times

SSRI treatment for postnatal depression brought long-term benefits for mothers and their offspring in the following years after childbirth, study findings showed.

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Opinion: It’s long past time for a more comprehensive Covid treatment approach

STAT

Because Covid cases and hospitalizations are no longer front-page news, many Americans might be surprised to learn that we are in the midst of a mini-surge. The latest data from the Centers for Disease Control and Prevention, from Aug. 12, confirm a 21.6% increase in Covid-19 hospitalizations from the prior week and a 21.4% increase in Covid-related deaths, demonstrating that Covid is not over and that Latinos and Blacks have reason to be concerned.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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MorningRX: August 31, 2023

Drug Topics

The FDA issues warning letters to 3 infant formula manufacturers for violations, and officials with the Department of Health and Human Services recommend reclassifying marijuana as a schedule III drug.

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A big insurer decides to cover naloxone for overdose; will others follow?

STAT

At long last, naloxone is available over the counter.  But now comes a moment of truth for the overdose-reversal medication: Will increased access help to save lives? And more immediately, can everyone who wants to buy naloxone at a pharmacy afford it?

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Headspace, Intermountain's Castell team up to expand behavioral health access

Fierce Healthcare

Digital mental health company Headspace is teaming up with Castell, Intermountain Healthcare’s value-based care subsidiary, to expand access to virtual mental health services. | The partnership will provide members of select insurance plans in Utah access to Headspace’s self-guided content, behavioral health coaching and therapy in an outcomes-based payment model.

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Johnson & Johnson slashes price of tuberculosis drug Sirturo after relinquishing patent protections

Fierce Pharma

Seven weeks after saying it would allow generic competition for drug-resistant tuberculosis (TB) treatment Sirturo (bedaquiline) in low- and middle-income countries (LMICs), Johnson & Johnson h | Seven weeks after saying it would allow generic competition for drug-resistant tuberculosis (TB) treatment Sirturo (bedaquiline) in low- and middle-income countries (LMICs), Johnson & Johnson has slashed its own drug's price by 55% to $130 for a six-month course.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Statin Therapy Can Reduce Risk of a Major Adverse Cardiovascular Event in Patients With HIV

Pharmacy Times

A combination of statin therapy and antiretroviral therapy may decrease the naturally higher risk of cardiovascular disease in patients with HIV.

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Sanofi shakes up leadership as specialty care head Sibold departs to pursue outside opportunity

Fierce Pharma

For six years, Sanofi's specialty care chief Bill Sibold has helped the company make the most of its Regeneron-partnered immunology superstar Dupixent. | Bill Sibold, who took over the company's specialty care unit in 2017 just after Dupixent's first approval, is leaving Sanofi effective immediately. The company further shook up its leadership by appointing a new R&D head, a chief digital officer and adding an entirely new position.

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Semaglutide Found Effective for Weight Loss in Patients With Heart Failure, Obesity

Pharmacy Times

After 1 year of treatment, semaglutide significantly improved physical function, which can improve quality of life outcomes and risk of death.

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Stem cell therapy delivers potential for sickle cell disease

European Pharmaceutical Review

New research published in the New England Journal of Medicine has indicated that stem cell gene therapy could provide a curative treatment for sickle cell disease (SCD). Based on new data from the Novartis Phase I/II clinical trial , which used the first therapy to target a new genetic area and use cryopreserved stem cells, trial participants reported a decrease in vaso-occlusive events.

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Coalition of 33 organizations endorses CMS' proposal to quickly cover new medical devices

Fierce Healthcare

The American Telemedicine Association, the College of Healthcare Information Management Executives (CHIME) and Otsuka America Pharmaceutical are among the groups in support of the Centers for Medic | Organizations signed a letter pledging support for a CMS-backed transitional coverage for emergency technologies pathway, which they say could improve patient care, prevent hospitalizations and reduce costs.

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Hallmark, Venmo join forces on secure money card gifting experience

Drug Store News

The Hallmark + Venmo cards aim to make it possible for customers to give a physical card with money through Venmo by removing the worry of lost cash or checks, the companies said.

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STAT+: Drug firms test medicines to halt Alzheimer’s before symptoms appear

STAT

Alzheimer’s disease has killed at least three women in Astrida Schaeffer’s family over two generations, leaving her feeling helpless and bereft. The first was her Polish-born maternal grandmother, who began showing symptoms when Schaeffer started college in 1981 and died seven years later. Then came her mother, a onetime Fulbright Scholar and high school language teacher who had been fluent in five languages but lost the ability to speak.

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Huggies, Walgreens raise awareness of U.S. families struggling with diaper need

Drug Store News

For every pack of Huggies Diapers purchased at Walgreens through September, Huggies will donate a day’s worth of diapers to the National Diaper Bank Network, up to one million diapers.

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STAT+: Pharmalittle: U.S. pharma layoffs continue to climb; senators push insulin makers for details of low-cost programs

STAT

Top of the morning to you, and a fine one it is. Blue skies and cool breezes are enveloping the Pharmalot campus, where the official mascots are bounding about the grounds and the usual street noise has dropped to a dull hum. As for us, we are immersed in the usual ritual — brewing cups of stimulation. Our choice today is the flavorful chocolate raspberry.

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In pleasant surprise for GSK, FDA approves Jakafi challenger Ojjaara in broad blood cancer use

Fierce Pharma

For the JAK inhibitor momelotinib, which GSK obtained in its $1.9 billion acquisition of Sierra Oncology, a three-month delay at the FDA was worth the wait. | For the JAK inhibitor momelotinib, which GSK obtained in its $1.9 billion acquisition of Sierra Oncology, the three-month extension of the FDA's review turned out to be worth the wait.

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How much is Mounjaro without insurance?

The Checkup by Singlecare

Is Mounjaro covered by insurance? | How much does Mounjaro cost without insurance? | How to get Mounjaro without insurance Mounjaro (tirzepatide) is a brand-name prescription drug FDA-approved to control blood sugar levels in people with Type 2 diabetes. However, some healthcare professionals prescribe Mounjaro off-label for weight loss. Injected once per week, tirzepatide increases insulin production, reduces appetite, and causes weight loss.

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Zevra strikes $91M buyout of Acer to catapult itself into commercial rare disease space

Fierce Pharma

Zevra Therapeutics has jumped the queue to become a commercial rare disease company, thanks to a fresh acquisition and the addition of a new marketed product. | Zevra is laying out $91 million to get its hands on rare disease compatriot Acer Therapeutics, the companies announced Thursday. Under the deal, which is expected to close in the fourth quarter, Acer is also in line to receive up to $76 million in potential cash payments tied to Contingent Value Rights (CVRs) around commercial and regula

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Morgan Health: How employers can take a greater role in improving care quality

Fierce Healthcare

Employers fund huge swaths of the healthcare system, yet the quality of care their employees receive varies widely. | Employers fund huge swaths of the healthcare system, and yet the quality of care their employees receive varies widely, a new study shows.

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Fierce Pharma Asia—Vyvanse generics; Lenvima's trial flop; Adagene's ADC breakup

Fierce Pharma

Generics to Takeda's blockbuster ADHD drug Vyvanse are now approved in the U.S. Merck and Eisai's Keytruda-Lenvima combo failed in another pivotal trial. | Generics to Takeda's blockbuster ADHD drug Vyvanse are now approved in the U.S. Merck and Eisai's Keytruda-Lenvima combo failed in another pivotal trial. ADC Therapeutics walked away from an antibody-drug conjugate partnership with Adagene.

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Hospitalisations for iron-deficient heart failure patients reduced with IV ferric carboxymaltose

Hospital Pharmacy Europe

The use of intravenous ferric carboxymaltose (FCM) in heart failure patients with iron deficiency reduces the risk of hospitalisation and cardiovascular death, according to research presented at the recent European Society for Cardiology (ESC) Congress 2023 in Amsterdam. Researchers undertook a meta-analysis of individual participant data from three randomised, placebo-controlled trials of FCM in adult patients with heart failure and iron deficiency: CONFIRM-HF , AFFIRM-HF and HEART-FID.

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Lawmakers call on FDA to issue stricter bone graft guidance

STAT

You’re reading the web edition of STAT Health Tech, our guide to how tech is transforming the life sciences.  Sign up to get this newsletter  delivered in your inbox every Tuesday and Thursday.

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Clopidogrel ineffective for majority of British south Asians, study finds

Hospital Pharmacy Europe

A genetic study has revealed how the use of clopidogrel in British patients of south Asian ancestry appears to be less effective at preventing recurrent myocardial infarction than in those of European descent. The study, which was published in the journal JACC: Advances , sought to assess the prevalence of common CYP2C19 genotype polymorphisms in a British south Asian population and correlate these with recurrent myocardial infarction risk in participants prescribed clopidogrel.

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Amit Etkin: the former Stanford professor pioneering a new treatment for depression

Outsourcing Pharma

More people are talking about mental illness than ever before. However, despite increased awareness, it remains one of the most neglected areas of public health globally, with research and quality of care lagging behind physical health conditions.

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Bimekizumab approved by MHRA for psoriatic arthritis and axial spondyloarthritis

Hospital Pharmacy Europe

Bimekizumab is now approved for use by the UK’s Medicines and Healthcare products Regulatory Agency ( MHRA) for the treatment of adults with active psoriatic arthritis (PsA) and active axial spondyloarthritis (axSpA), its manufacturer UCB has announced. The MHRA approval of bimekizumab (brand name Bimzelx) makes the drug the first approved treatment both both conditions that works as a dual IL-17A and IL-17F inhibitor, both of which have ben implicated in driving the inflammatory processes

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Grubhub brings Amazon's Just Walk Out technology to select campuses

Drug Store News

Students can save time by skipping the checkout line and are automatically charged via their synced campus payment method in the Grubhub app.

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