Fri.Sep 08, 2023

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Norovirus Vaccine Candidate Shows Positive Results in Phase 2 Trial

Drug Topics

Vaxart’s VP1-based bivalent oral tablet vaccine was developed to target the norovirus GI.1 Norwalk and GII.4 Sydney strains, which are the predominant strains affecting humans.

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Increased Vitamin D Intake Can Decrease Symptoms of Depression, Anxiety

Pharmacy Times

Although findings indicate a relationship between vitamin D and mood disorders, further research is needed to clarify efficacy of specific vitamin D levels, as well as supplement dose and form.

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How a supplement company became a haven for health misinformation

STAT

On a Friday afternoon in July, as many New Yorkers fled the scorching city streets, a couple of dozen out-of-towners descended on Times Square. They came bearing gold letter balloons spelling out LFVN, the stock symbol for LifeVantage, the company they’d come to promote, and foam cutouts of its navy blue supplement bottles. LifeVantage’s chief executive officer, Steve Fife, rang the Nasdaq exchange’s closing bell, a celebration of the Utah-based company’s new products

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Study: Financial Incentives Increases PrEP Initiation, Adherence for HIV

Pharmacy Times

Applying novel and effective behavioral economics for pre-exposure prophylaxis dissemination programs could help to tailor the programs to the populations and settings of high HIV burden areas.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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ALS advocates say criticism of new drugs misses bigger picture

STAT

A diagnosis of ALS has long been seen as a death sentence. But in recent years, progress in the world of ALS research and drug development has come to embody a conundrum with far broader implications: The balance between moving aggressively on promising new cures and guarding against false hope.

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Research Identifies Defined Subtypes of Follicular Lymphoma, Marginal Zone Lymphoma

Pharmacy Times

Correctly diagnosing specific follicular lymphomas and marginal zone lymphomas requires knowledge of the clinical context, including the site of involvement, age, and clinical presentation.

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More Trending

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Point-of-Care Test Reagents Could Aid Risk Assessment for In-Home Care of Older Adults

Pharmacy Times

In addition to improving risk evaluation in older adults at home, point-of-care testing may help clinicians manage patients with dementia who cannot communicate and those living in depopulated areas.

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Opinion: STAT+: Sanofi CEO Paul Hudson: The right way to bring AI into pharma

STAT

While it’s widely accepted that the pharma industry is innovative in R&D, it is also true that it can be slow at embracing technological revolutions. Many people have criticized pharma companies for being slow to adopt AI. Indeed, some CEOs I talk to are concerned about too widely adopting AI, citing fears of unknown threats. But as the CEO of Sanofi, I don’t believe those challenges should guide our thinking or adoption of AI in the pharma business, as AI has the potential to

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Breaking Barriers and Inspiring Change: Female Pharmacy Owner Paves the Way for Success in Independent Practice

Pharmacy Times

With pharmacies around the country shifting to provide more comprehensive care and becoming true health care destinations, Chichi Ilonzo Momah, PharmD, RPh said she is excited for the future of the field.

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How Seth Rogen and Lauren Miller Rogen are using comedy to support Alzheimer’s care

STAT

Alzheimer’s isn’t funny. But comedy can still be a weapon in the fight against this deadly degenerative disease. Since 2012, comedian and filmmaker Lauren Miller Rogen and her husband, actor and comedian Seth Rogen, have used humor to help raise awareness for Alzheimer’s disease and funds for at-home caregiving through their nonprofit Hilarity for Charity.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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Next-Generation Therapy Analyzes Intestinal Phages, Propelling Future of C. difficile Treatment

Pharmacy Times

Using metagenomic information, the technology isolates phages whose enzymes can specifically target the bacteria that causes C. difficile infection.

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STAT+: Why Novartis is changing the name of its research labs

STAT

Swiss drugmaker Novartis’ research and development hub has a new name — and a new guiding strategy. The hub, which is headquartered in Cambridge, Mass., and for years has been known as Novartis Institutes for BioMedical Research, or NIBR, will soon simply be known as Novartis BioMedical Research. But that’s not the only thing that’s changing, Fiona Marshall, the hub’s president, told a virtual audience Thursday during the 2023 STAT Future Summit.

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Intermountain, UPMC switching from Oracle's Cerner EHR to Epic enterprisewide

Fierce Healthcare

Intermountain Healthcare, a health system that operates 33 hospitals across seven western states, is transitioning from Oracle Health's Cerner electronic health record to rival Epic, citing higher | Intermountain Healthcare, a health system that operates 33 hospitals across seven western states, is transitioning from Oracle Health's Cerner EHR to its rival Epic, citing higher physician satisfaction scores as one key factor.

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STAT+: Lawsuit raises antitrust and kickback allegations around cancer patient referrals

STAT

A large independent group of oncologists in Philadelphia is suing the area’s dominant hospital system, Jefferson Health, alleging the system is violating federal antitrust and kickback laws by creating a “concerted campaign to eliminate” the group’s “presence in the oncology marketplace.” The lawsuit resurfaces longstanding concerns associated with hospitals buying up physician groups and then forcing those physicians to refer patients to the hospitals&#

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Study: IVIG Worth Considering for Severe, Critical COVID-19 Infection

Pharmacy Times

Multiple studies show that it might be more effective to administer intravenous immunoglobulins at an earlier stage of disease progression.

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New Study Highlights Importance of Mpox Vaccination

Drug Topics

Patients who were vaccinated and reinfected showed symptoms of few lesions, little mucosal disease, and minimal analgesia requirements.

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House committees introduce new healthcare price transparency legislation

Fierce Healthcare

A trio of House committees unveiled new legislation (PDF) Friday to lower costs and increase transpar | Several house committees dropped new legislation Friday meant to improve price transparency for patients and employers. Here's what they're proposing.

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An uncommon thyroid diagnosis led to an unexpected, all-too-visible side effect

STAT

Annie Larsson, 40, is no stranger to chronic conditions. She was diagnosed with type 1 diabetes at a young age and had it “completely managed” for years. Then, right before the Covid pandemic began, she was diagnosed with Graves’ disease, a condition that can make a person’s thyroid overactive. A thyroid removal surgery later, all she had to worry about was taking her thyroid hormone replacement medication every day — a to-do she was accustomed to because of he

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Pharmacy Focus: Psychedelic Pharmacy - Ibogaine Offers Unique Benefits

Pharmacy Times

Although it has some daunting adverse effects, Glenn Short, PhD, said ibogaine offers unique biological and therapeutic effects.

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Opinion: How the drug price negotiation program could affect Medicare Part D beneficiaries

STAT

After the recent announcement of the first 10 drugs selected for Medicare price negotiation, much has been discussed about the drugs that were selected and the magnitude of price decreases that can be achieved. Less attention has been given to what this all means for Medicare beneficiaries. The negotiation, informed by confidential data from manufacturers and analysis by the Centers for Medicare and Medicaid Services, will result in a maximum fair price for each drug, which will be announced Sep

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MorningRX: September 8, 2023

Drug Topics

CDC survey finds Interventions are needed to facilitate the implementation of updated pneumococcal vaccine recommendations, HHS proposes a new rule the seeks to prohibit discrimination based on disabilities, and a new report says there is a need for improved access to pediatric subspecialty care.

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Insulin Sensitizers May Be Making a Comeback

Pharmacy Times

Researchers Have Identified New Uses for Them, Including in the Treatment of Polycystic Ovary Syndrome and Infertility.

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Video: The Importance of Charitable Patient Assistance Foundations

Drug Topics

Charitable patient assistance foundations do crucial work to help individuals access necessary health care.

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WCLC: Tagrisso's chemo combo shows edge, but AstraZeneca thinks monotherapy remains king in lung cancer

Fierce Pharma

AstraZeneca’s Tagrisso is the standard of care in newly diagnosed, EGFR-mutated non-small cell lung cancer (NSCLC). | AstraZeneca hopes to offer patients with first-line, EGFR-mutant lung cancer a new option in the combination of Tagrisso and chemotherapy. But the lack of a patient survival showing raises some questions for the combo.

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Phase 3 Study of Macitentan 75mg to Treat CTEPH Will Stop Research

Pharmacy Times

A phase 3 study assessing macitentan 75mg treatment for CTEPH was stopped, although another study using macitentan will continue.

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Is it safe to mix Lexapro and alcohol?

The Checkup by Singlecare

Many people feel having a drink can help take the edge off in certain situations, such as after a hectic day at work or at a social gathering. But if you’ve been prescribed Lexapro ( escitalopram oxalate ), you may want to think twice before sipping your favorite beer, wine, or cocktail. It’s important to know how alcohol interacts with your medications, and this is especially true of prescription antidepressants.

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Phase 2 Study Shows Promising Results to Lower SBP, Treat Hypertension with Zilebesiran

Pharmacy Times

The Phase 2 KARDIA-1 Study met its primary endpoint of lower systolic blood pressure with the use of zilebesiran.

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Danco takes mifepristone restrictions lawsuit to the Supreme Court

Fierce Pharma

The legal kerfuffle over the FDA’s 2000 approval of Danco Laboratories’ abortion pill mifepristone, also known as Mifeprex, is heading to the Supreme Court. | Friday, Danco Laboratories asked the Supreme Court to overturn a recent U.S. Court of Appeals for the Fifth Circuit ruling that would severely limit access to the abortion pill mifepristone.

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Self-Care Measures Can Help Prevent and Treat Headaches

Pharmacy Times

Pharmacists can make clinical recommendations tailored to patients’ individual needs.

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Hospital Pharmacy Europe launches web browser notifications

Hospital Pharmacy Europe

Users of the Hospital Pharmacy Europe website can now enjoy upgraded functionality with the launch of a new notification system. Enhancing the experience and usability of the website, users can opt in to receive alerts when new content is published, allowing them to easily stay up to date with key developments in secondary healthcare. This complements the existing notification system built into the Hospital Pharmacy Europe App, which was launched in summer 2022 and is available on iOS and Androi

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STAT+: Pharmalittle: Novartis R&D hub’s name change reflects strategy shift; Lilly’s Mounjaro backed by U.K. watchdog

STAT

Good morning, Pharmalittle family! Adam Feuerstein here, filling in for Ed. My morning coffee was brewed with Peru Cajamarca beans, sourced by Equator and lightly roasted to reveal “notes of almond, tamarind and white grape.” Honestly, I’m not getting any of those flavors, but it’s still a damn good cup of joe. Very smooth.

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NICE recommends new type 2 diabetes treatment

European Pharmaceutical Review

Eli Lilly ’s Mounjaro (tirzepatide), has been recommended to treat poorly controlled type 2 diabetes in adults alongside diet and exercise. National Institute for Health and Care Excellence (NICE) final draft guidance recommends tirzepatide as a new treatment option for this indication. Compared with semaglutide , insulin therapy or a placebo, tirzepatide demonstrated that 81 percent to 97 percent of people achieved better glucose control in clinical trials.

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Fierce Pharma Asia—Astellas' brief IRA fight; Otsuka's psychedelic buy; Takeda's court loss

Fierce Pharma

Three Japanese pharma companies lead our news stories from Asia this week. Astellas has abandoned its challenge against the Inflation Reduction Act. | Astellas has abandoned its challenge against the Inflation Reduction Act. Otsuka bought a Canadian psychedelic biotech. And Takeda is ordered to pay AbbVie nearly $480 million because of a manufacturing hiccup.

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New Product Planning: The Function's Evolution in Pharma

PharmExec

With an organization's future commercial success under its remit, the NPP function has rapidly progressed to a prominent role in the biopharma industry—but evidence-generation strategies must evolve with an eye toward emerging trends and technologies.

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