Tue.Jul 25, 2023

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Women Treated for Breast Cancer Experience Accelerated Biological Aging

Drug Topics

Radiation therapy was associated with the largest increase, compared to chemotherapy or endocrine therapies.

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Once-Weekly Insulin Analogue Demonstrates Promising Results for Those With Type 2 Diabetes

Pharmacy Times

Patients with type 2 diabetes receiving once-weekly insulin icodec were more likely to reach a hemoglobin A1C level below 7% compared to those who received once-daily insulin analogues.

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Analysis Estimates 100 Million Non-COVID-19 Adult Vaccines Missed

Drug Topics

The report references adult vaccines, in terms of volume of use, for influenza, diphtheria and tetanus (Td), diphtheria, tetanus and pertussis (TDaP), hepatitis B, herpes zoster and pneumococcal.

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Axatilimab Produces Significant Response in Patients with Fatal Post-Transplant Complication

Pharmacy Times

Co-developers Incyte and Syndax will submit a biologics license application to the FDA at the end of 2023 based on the results of a phase 2 trial among adult and pediatric patients with chronic graft-versus-host disease.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Cigna hit with class action alleging it used an algorithm to reject claims

Fierce Healthcare

Two Cigna members have hit the insurer with a class action lawsuit, accusing the company of using an algorithm to improperly deny scores of patient claims. | Two Cigna members have hit the insurer with a class action lawsuit, accusing the company of using an algorithm to improperly deny scores of patient claims.

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Maternal Hepatitis C During Pregnancy Increases Risk of Adverse Perinatal Outcomes

Pharmacy Times

The study authors said that further investigation is needed to explore specialized care for mothers and newborns who are affected by hepatitis C infections during pregnancy.

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Experts Raise Questions, Potential Answers About Why COVID-19 Has Drastically Changed RSV Epidemiology

Pharmacy Times

The prolonged lack of viral exposure has likely increased the pool of children and adults vulnerable to respiratory syncytial virus, but questions remain.

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Opinion: Enough with the health care policy patchwork. It’s time for universal insurance

STAT

Everyone knows that the United States is the only high-income country without universal health insurance. According to the standard narrative, this is the inevitable result of U.S. exceptionalism — our different values, culture, and institutions. Not so. The impetus for universal coverage is as strong in the United States as in any other country.

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Patients Who Self-Report as Recovered From SARS-CoV-2 Present No Cognitive Deficits Following Infection

Pharmacy Times

Further work is necessary to monitor and develop understanding of recovery for individuals with ongoing COVID-19 symptoms.

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STAT+: As Alzheimer’s drugs hit the market, the race for early detection blood tests heats up

STAT

With the advent of disease-modifying Alzheimer’s drugs, everyone in the world of Alzheimer’s diagnostics is bracing for the crush. Based on their ability to slow cognitive decline, the Eisai/Biogen drug Leqembi won full approval from the FDA this month, and donanemab by Eli Lilly could be approved by year end. Clinicians now have to decide which patients are most suitable for treatment, which means better Alzheimer’s tests need to be developed.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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Science Summarised: NF2 and Sporadic Vestibular Schwannoma

NF2 BioSolutions

It’s NF2 science, but summarised! The previous blog posts in this series: Science Summarised: Potential New Drugs for Hearing Loss Science Summarised: All Things Meningioma This blog was written by NF2 BioSolutions PhD student Grace Gregory. [Image Description] Grace Gregory in the laboratory at the University of Manchester. — Exciting news!

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Biogen, working through a 'transition,' plots 1,000 more layoffs by 2025

Fierce Pharma

In reporting its first-quarter earnings, Biogen said it would halt the development of at least four investigational drugs to allow the company to focus on more lucrative opportunities. | In a sizable cost-cutting measure, Biogen will lay off 1,000 employees by 2025, it announced in presenting its second quarter earnings. With the company starting 2023 with 8,725 employees, that’s an 11.5% reduction of the workforce.

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Hospitals are seeing higher acuity patients, struggling to discharge to post-acute care settings, report finds

Fierce Healthcare

Hospitals are finding it harder to place patients into post-acute care settings, a new report finds. | The number of referrals to nursing homes and home health agencies per patient has increased over the last year, as has patient acuity. At the same time, referral rejection rates are also on the rise.

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FDA clears Tarsus' Xdemvy as first treatment for common eyelid disease

Fierce Pharma

Patients with the eyelid disease Demodex blepharitis can now see a cure in Tarsus Pharmaceuticals’ Xdemvy, the first FDA-approved treatment for an ailment that affects some 25 million Americans.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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STAT+: Biogen says it will cut costs by $700 million, slash 1,000 jobs

STAT

Biogen announced a new round of cost cuts Tuesday, saying that it plans to save $700 million in operating costs and cut 1,000 jobs by 2025. The company also released second quarter sales and earnings that handily topped the forecasts of Wall Street analysts. In early morning trading, Biogen shares rose more than 1%. Biogen is attempting to recover from a series of corporate stumbles, the biggest of which involved the development and launch of the Alzheimer’s drug Aduhelm.

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Bayer expects gloomier 2023 as lower glyphosate sales bolster breakup advocates' case

Fierce Pharma

Just as the calls for a business separation grow louder at Bayer, the company’s weedkiller performance is bolstering the argument with dramatically declining sales. | Just as the calls for a business separation grow louder at Bayer, the company’s weedkiller performance is bolstering the argument with dramatically declining sales.

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STAT+: Truvian presents data for its desktop blood-testing device in a field still in Theranos’s shadow

STAT

SAN DIEGO — Truvian Health, a San Diego blood diagnostics company, shared data on Tuesday showing that its benchtop instrument’s results are largely consistent with those generated by large central laboratories. But while the results lend support for the company’s vision of decentralized and widely available clinical testing, they also resurface questions about the value of an approach widely associated with the now defunct and notorious Bay Area startup Theranos.

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GLP-1 drugs are still in demand. Insurers are cutting back coverage in response, Found study shows

Fierce Healthcare

As demand surges for GLP-1 therapies, insurers are pulling back on coverage, according to new data from obesity care provider Found. | Sarah Jones Simmer, CEO of Found, said that the trends are likely the result of irresponsible prescribing for recreational reasons causing the pendulum to swing "all the way in the other direction," and it's leading to patients who have genuine medical need struggling to access these therapies.

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The AMA’s new president on medicine’s ‘AI era’ and the uncertain future of telehealth

STAT

Much has been made of Jesse Ehrenfeld’s career of firsts. The current president of the American Medical Association, inaugurated in June , has long advocated for safe and equitable care for sexual and gender minorities, leading to an inaugural National Institutes of Health award for his research in the area. The anesthesiologist was the youngest-ever officer of the Massachusetts Medical Society, and this year became the first openly gay president of the AMA.

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How to Find the Best Digital Marketing Agency for Your Business 

Pharma Marketing Network

In today’s digital world, partnering with a competent and reliable digital marketing agency is crucial for businesses seeking to enhance their online presence, reach their target audience, and achieve their marketing goals. However, with countless agencies available, it can be overwhelming to find the right one that aligns with your business objectives.

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STAT+: South Africa faces court hearing over opaque Covid-19 vaccine contracts

STAT

A hearing began in a South Africa court on Tuesday to determine whether the government overpaid for Covid-19 vaccines, an allegation made by advocacy groups who contend that a lack of transparency may have masked pharmaceutical profits at the public’s expense. At issue are contracts signed by the South African government with several companies — including Johnson & Johnson and Pfizer — that provided millions of Covid-19 vaccines during the pandemic.

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J&J, GSK's ViiV tout switching study showing patients prefer their long-acting HIV med Cabenuva over Gilead rival

Fierce Pharma

To make Cabenuva the standard treatment option for HIV, Johnson & Johnson and GSK-owned ViiV Healthcare must first dethrone Gilead Sciences’ once-daily stalwart Biktarvy. | To make Cabenuva the standard treatment option for HIV, Johnson & Johnson and GSK-owned ViiV Healthcare must first dethrone Gilead Sciences’ once-daily stalwart Biktarvy.

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Biden admin proposes new mental health parity regulations

Fierce Healthcare

Amid a worsening mental health crisis, the Biden administration is proposing a slew of regulatory changes aimed at improving access to critical care. | Amid a worsening mental health crisis, the Biden administration is proposing a slew of regulatory changes aimed at improving access to critical care.

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Novel antibody therapeutic demonstrates potential in GVHD

European Pharmaceutical Review

Axatilimab, an anti-CSF-1R antibody to treat chronic graft-versus-host disease (GVHD) has, in a pivotal Phase II trial, demonstrated overall response rates (ORR) of 74 percent, 67 percent and 50 percent, within the first six months of treatment. “[It] is the first investigational chronic GVHD treatment to target inflammation and fibrosis through the inhibition of disease associated macrophages,” stated Michael A Metzger, Chief Executive Officer of Syndax Pharmaceuticals.

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AHIP, AMA, NAACOs team on playbook for value-based care

Fierce Healthcare

AHIP, the American Medical Association and the National Association of ACOs have teamed up to release a playbook that aims to arm stakeholders with best practices for value-based care. | Three major national organizations released a playbook to help payers and providers adapt to value-based care.

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How to Customize Your Audience in Ads Manager for the Pharma Industry 

Pharma Marketing Network

Ads Manager is a powerful platform that can help pharma companies reach their target audience and achieve their marketing goals. One of the ways to do this is to customize your audience. This means targeting your ads to people who are most likely to be interested in your products or services. Here are some tips for customizing your audience in Ads Manager for the pharma industry: Use demographics: You can target your ads based on demographics, such as age, gender, location, and interests.

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CHS selling 3 Florida hospitals to Tampa General Hospital for $290M

Fierce Healthcare

Community Health Systems (CHS) announced that it has signed a deal to sell three Florida hospitals to Tampa General Hospital for roughly $290 million. | The divestiture of Bravera Health Brooksville, Bravera Health Seven Rivers and Bravera Health Spring Hill is slated to close later this year pending regulatory approval and other customary closing conditions.

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FibroGen CEO Conterno, who scrapped post-Lilly plans over roxadustat hype, resigns after launch setbacks

Fierce Pharma

Hopes around FibroGen’s anemia drug roxadustat were high in early 2020 when Enrique Conterno arrived as the company’s new CEO. | Enrique Conterno has resigned from the FibroGen CEO post for “personal reasons,” the company said Tuesday. As FibroGen looks for a permanent successor, the company’s chief commercial officier Thane Wettig will don the mantle of interim chief executive officer.

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Teladoc reports higher Q2 revenue, bullish on opportunities for virtual weight management, mental health

Fierce Healthcare

Editor's Note: The article has been updated with information from Teladoc's earnings call with investors late Tuesday afternoon. | Teladoc is doubling down on its strategy to focus on "whole person care" through its virtual care platform. The telehealth provider is seeing strong growth across its chronic care programs and virtual mental health and is eyeing opportunities in the booming weight management market.

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STAT+: Drug from Stoke shows lower activity against childhood epilepsy, prompting search for better dose

STAT

Stoke Therapeutics is still seeking an effective dose for an experimental drug to treat a severe form of childhood epilepsy, following the release of updated data Tuesday that showed disappointing reductions in convulsive seizure activity. In the latest look at an ongoing mid-stage study, three monthly injections of the Stoke drug, called STK-001, given at a 45-mg dose, resulted in a median 18% reduction in convulsive seizure activity, compared to baseline.

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Healthcare tops all industries when it comes to money lost in data breaches: report

Fierce Healthcare

Data breaches hurt all industries, but this is especially true for healthcare, which has lost the most financially to these incidents, according to a new report. | Healthcare seems particularly vulnerable to data breaches, and the problem’s gotten worse since COVID-19, according to a report published by IBM Security. The average cost of a data breach in healthcare grew 53.3% since 2020.

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Promoting Medication Safety Improves Health Outcomes

Pharmacy Times

Pharmacists should provide guidance on issues such as proper drug disposal and potential drug interactions.

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How to Increase SEO on Google Ads for the Pharma Industry

Pharma Marketing Network

Google Ads is a great way to reach a wider audience for your pharma business. However, if you want to get the most out of your Google Ads campaigns, you need to optimize them for SEO. Here are some tips on how to increase SEO on Google Ads for the pharma industry: Use relevant keywords: When you’re creating your Google Ads campaigns, make sure to use relevant keywords.

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Universal Health Services revises guidance after Q2's $171.3M profit, higher volumes

Fierce Healthcare

King of Prussia, Pennsylvania-based Universal Health Services (UHS) reported a $171.3 million net gain ($2.42 per diluted share) for the second quarter of 2023, up slightly from the $164.1 million | The for-profit chain logged a 6.8% rise in net revenues over Q2 2022, with gains split across both of its acute and behavioral health businesses.

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