Wed.Dec 20, 2023

article thumbnail

Patients Hospitalized with COVID-19, Flu at Increased Risk of Long-Term Health Effects

Drug Topics

Patients hospitalized for either virus had an increased risk of death, hospital readmission, and health problems in multiple organ systems over 18 months of follow-up.

Hospitals 195
article thumbnail

Experimental Pneumococcal Vaccine Successfully Prevents Disease in Animal Models

Pharmacy Times

Investigators aim to find a substitution for incomplete Freund adjuvant, which is not suitable for use in humans but shows a strong response to antigen-specific systemic immune responses.

Vaccines 145
Insiders

Sign Up for our Newsletter

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Trending Sources

article thumbnail

Pregnant cancer patients often have to terminate. Abortion pill restrictions could make that choice even harder

STAT

WASHINGTON — The patient had already made the agonizing decision to start chemotherapy to address her colon cancer, even though she was 30 weeks pregnant. Within a day, the decisions got harder: her colon perforated, and the pain was excruciating. She would need urgent surgery — and she would have to undergo an emergency C-section immediately.

article thumbnail

Formulated Toothpaste Could Improve Allergic Reactions to Peanut Allergy

Pharmacy Times

The results found that INT301 met both its primary and secondary endpoints and could be a safe and effective option for individuals that experience food allergies.

149
149
article thumbnail

Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

article thumbnail

After ‘SNL’ skit on sickle cell CRISPR therapy, advocates cite errors and stereotypes

STAT

Mary Brown was sipping coffee at home in Ontario, Calif., Sunday morning when a friend sent a video clip that ruined her breakfast. It contained a skit from “Saturday Night Live” the night before about the new gene therapies for sickle cell disease. In it, workers gather for an office white-elephant-style gift exchange. A white employee, played by Kate McKinnon, gives a Black employee with sickle cell, played by Kenan Thompson, enrollment in “Vertex Pharmaceutical and CRISPR

145
145
article thumbnail

Study: Neighborhoods With Lower Socioeconomic Status Linked to Lower Adherence Rates for Those With Heart Failure

Pharmacy Times

The results of the study show the importance of considering neighborhood-level disparities to address and improve medication adherence, according to investigators.

149
149

More Trending

article thumbnail

Inquiry By Senate Finance Representatives Finds Pharmacies Fail to Protect Privacy of Medical Records

Pharmacy Times

The pharmacies, which include 8 major chains, were revealed to provide prescription records to law enforcement agencies without court orders or warrants.

article thumbnail

How to avoid prednisone withdrawal

The Checkup by Singlecare

Millions of people are prescribed prednisone each year for conditions that range from psoriasis and eczema to multiple sclerosis and rheumatoid arthritis. Prednisone belongs to a class of drugs called corticosteroids (also sometimes called glucocorticoids)—steroids that reduce inflammation in the body by replacing cortisol, a hormone produced in the adrenal glands, and slowing down an overactive immune system.

article thumbnail

Study: Telemonitoring After Heart Failure Comparable to Standard of Care

Pharmacy Times

Individuals received 4 daily short messages that reminding them to participate in self-care, active engagement, and early intervention for the first 30 days of the study.

139
139
article thumbnail

At a hospital’s teaching kitchen, patients get a taste of food as medicine

STAT

BOSTON — Tony McKoy, Jr. was ready to eat. Black chef’s hat on his head, apron tied on, the five-year-old contemplated his favorite foods, prompted by his mother, Shaquana Peebles. “Pineapple!” he said, savoring its sweetness with his eyes closed while he imagined biting into one. Also, brownies made with black beans. PB&J.

141
141
article thumbnail

What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

article thumbnail

Study Results Suggest New Opportunities to Improve Future HIV Vaccine Candidates

Pharmacy Times

The study authors note that the findings could be significant in future HIV vaccine design and development, as well as new approaches to HIV immunotherapy.

Vaccines 145
article thumbnail

2024 Outlook: 'Blurring of the lines' as providers, retailers and payers plotting primary care plays

Fierce Healthcare

Health systems, insurers, retailers like CVS and tech companies like Amazon are all scrambling for a bigger piece of the medical pie. | Patients are looking for easier access to medical services and more convenience and this is opening big opportunities for insurers, retailers, tech companies and nontraditional players to muscle their way into primary care.

Insurance 133
article thumbnail

STAT+: 3 trends to watch in biotech in 2024

STAT

Every winter, like Punxsutawney nobles, biotech’s many thought leaders gather in San Francisco to pick apart the year that was and prognosticate about the one to come. The consensus, in good markets and bad, is almost always cautious optimism for boom times ahead, a prediction that in recent years has had groundhog-level accuracy. But after two years of steady decline, 2024 might finally prove them right.

132
132
article thumbnail

After Amryt buyout, Chiesi scores with FDA nod for rare skin disease treatment Filsuvez

Fierce Pharma

Seven months after Krystal Biotech became the first company to gain FDA approval to treat the rare, devastating skin disease epidermolysis bullosa (EB), Chiesi Farmaceutici has followed suit. | Seven months after Krystal Biotech became the first company to gain FDA approval to treat the rare, devastating skin disease epidermolysis bullosa (EB), Chiesi Farmaceutici has followed suit.

FDA 131
article thumbnail

5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

article thumbnail

STAT+: SEC charges former CEO of pain relief device company with $41 million fraud

STAT

The Securities and Exchange Commission on Tuesday charged the former CEO of Stimwave, a company that sold devices containing dummy pieces of plastic, with defrauding investors out of $41 million.  Laura Perryman led Stimwave, which sold nerve stimulation devices to combat pain, from 2010 to 2019, when the fraud came to light. Under her leadership, Stimwave warped the design of the device to better align with insurance codes, resulting in unnecessary plastic components that allowed the compa

Insurance 128
article thumbnail

Obesity, primary care startup Knownwell raises $20M, launches program for teens

Fierce Healthcare

Knownwell, an integrated primary and obesity care provider, is launching a new teen program for weight management. | The new program aims to create a patient-focused environment to uncover and treat the root cause of early obesity. The care model is built on involving the teen’s family with nutritional counseling, behavioral health services and pharmacotherapy when appropriate.

126
126
article thumbnail

STAT+: In another blow, Argenx antibody therapy fails in trial for skin blistering condition

STAT

LONDON — The Belgian company Argenx said Wednesday that its closely watched antibody therapy failed to outperform placebo in a Phase 3 trial in an autoimmune condition that causes the skin to blister — the second setback in less than a month for the biotech and its drug. Argenx’s stock was down roughly 30% in early trading. Argenx said that it was stopping development of its drug, called efgartigimod, in pemphigus, a disease that causes blisters and sores on the skin and muc

127
127
article thumbnail

Researchers Find Language Gaps Could Interfere with Pediatric Allergy Diagnoses

Pharmacy Times

Language gaps resulted in barriers and underdiagnosing in children with common allergies, limiting support for these patients and their families.

131
131
article thumbnail

Opinion: The U.S. must raise federal alcohol taxes to address the alarming rise in alcohol use

STAT

Eleven years ago, two days before Christmas, my 24-year-old brother, who was a university graduate and former law student, died from a self-inflicted gunshot wound. After a decade of hard and continuous drinking interspersed with addiction and mental health treatment, he could not sustain his recovery. His suicide came on the heels of my mother’s death a year before, and just weeks later, my grandfather died in a car accident.

126
126
article thumbnail

CDC Report Shows Decline in Cigarette Smoking During Pregnancy

Drug Topics

A new report from the CDC demonstrated a decrease in cigarette smoking across all race and ethnic groups from 2016 to 2022, illustrating a promising trend with potential public health benefits.

98
article thumbnail

A medical student was isolated by an autoimmune disorder. Poetry was a way out

STAT

When Leena Danawala’s poetry was published in JAMA last month, the medical journal became just about the only place online to publicly showcase her art. Danawala, a 34-year-old rheumatologist in the Chicago area, had been writing poetry for over a decade but only posted about it occasionally on her Instagram. During her two-year rheumatology fellowship at Ohio State University, she suddenly felt the urge to share.

124
124
article thumbnail

VA deepens partnership with AppliedVR to expand access to immersive therapeutics

Fierce Healthcare

The Veterans Health Administration is tapping AppliedVR to expand military veterans' access to virtual reality-based therapy for chronic lower back pain. | The Veterans Health Administration is tapping AppliedVR to expand military veterans' access to virtual reality-based therapy for chronic lower back pain.

121
121
article thumbnail

BioNTech wins round in CureVac mRNA patent dispute

pharmaphorum

Shares in CureVac have plummeted after a German court ruled that a patent it holds on mRNA-based COVID-19 vaccines was invalid. The validity of the patent is at the heart of patent litigation between CureVac and fellow German biotech BioNTech and its partner Pfizer, claiming infringement by their Comirnaty coronavirus shot.

Vaccines 119
article thumbnail

Opinion: Racism infects neuroscience’s past and present. What about its future?

STAT

De-Shaine Murray is working at the cutting edge of neurotechnology. As a postdoctoral fellow at Yale, he is developing a device to monitor the brain following traumatic brain injury or stroke. He is also trying to fight the long legacy of racism in neuroscience. During 2020, when it was difficult to conduct research, he said, “I got the chance and the ability to read more widely and to just look into the legacy of neuroscience.

112
112
article thumbnail

Calliditas wins over FDA for full approval, broader label on kidney disease drug Tarpeyo

Fierce Pharma

Two years after securing an accelerated approval for its primary immunoglobulin A nephropathy (IgAN) therapy Tarpeyo (budesonide), Calliditas Therapeutics has

Labelling 124
article thumbnail

Rite Aid's 'reckless' use of AI facial recognition tech earns 5-year ban from FTC

Fierce Healthcare

Rite Aid has been hit with a five-year ban on the use of AI facial recognition technologies after the Federal Trade Commission (FTC) said the retail pharmacy chain “failed to implement reasonable p | The retail pharmacy chain's spotty facial recognition and "persons of interest" database generated "thousands" of false-positives, particularly among women and people of color, the FTC says.

115
115
article thumbnail

Tralokinumab for Atopic Dermatitis Approved for Adolescents by FDA

Drug Topics

Tralokinumab is the first form of atopic dermatitis treatment that targets the interleukin-13 cytokine, the main source of atopic dermatitis symptoms.

FDA 98
article thumbnail

Editor's Corner—Fierce Health Payer's top 10 stories of 2023

Fierce Healthcare

Among our most-read stories of the year, one topic clearly rose to the top: Medicare Advantage. | Many of the most-read health insurance stories from Fierce Healthcare in 2023 center on Medicare Advantage.

Insurance 114
article thumbnail

STAT+: Pharmalittle: Curevac loses key patent in battle with BioNTech; Abernethy to step down as Verily CMO

STAT

Good morning, everyone, and how are you today? We are doing just fine, thank you. Given that this is already the middle of the week and we have survived this far, no reason not to continue, yes? Just consider the alternatives. In fact, this modest accomplishment calls for celebration. So please join us in quaffing a ritual cup of needed stimulation.

Vaccines 106
article thumbnail

Palatin sells female libido drug Vyleesi to Cosette for $12M, plus more in potential milestones

Fierce Pharma

In 2020, Palatin Technologies paid $12 million to regain the rights in North America to its struggling female libido drug Vyleesi. | In 2020, Palatin paid $12 million to regain the rights in North America to its struggling female libido drug Vyleesi. Three years later, the New Jersey company has sold the treatment for the same up-front figure—$12 million—in a deal that indicates the medicine is unlikely to ever make a significant impact in the market.

109
109
article thumbnail

Apixaban Diltiazem Interaction

Med Ed 101

I recently came across a clinical issue in my practice as a consultant pharmacist to assisted living and long-term care facilities. The item in question was how to manage the apixaban diltiazem interaction. Apixaban Diltiazem Interaction Defined Apixaban is significantly metabolized by CYP3A4. This liver enzyme is significantly inhibited by diltiazem.

article thumbnail

Glass specialist Schott Pharma touts 2023 sales growth, Serbia expansion and hiring plans

Fierce Pharma

Following an IPO and ahead of its fiscal 2023 earnings release next month, German drug containment and delivery specialist Schott Pharma is trumpeting its recent momentum. | Following an IPO and ahead of its fiscal 2023 earnings release next month, pharma glass specialist Schott Pharma is trumpeting its recent momentum. Over the course of its recent fiscal year, Schott Pharma charted a 9% year-over-year revenue boost to €899 million (about $986 million), the company said Tuesday.

104
104
article thumbnail

Myelofibrosis Care: Pharmacist Role and Treatment Challenges

Pharmacy Times

Zahra Mahmoudjafari, PharmD, MBA, BCOP, FHOPA, and a panel of pharmacists exploring explore pharmacist roles in myelofibrosis care, treatment challenges, patient outcomes, and pharmacist responsibilities within interdisciplinary teams.

94
article thumbnail

Argenx's Vyvgart Hytrulo comes up short again, this time in the rare disease pemphigus

Fierce Pharma

Less than one month after reporting a trial fail for Vyvgart Hytrulo in a rare bleeding disorder, argenx has swung and missed in a group of chronic blistering diseases. | After a swing and miss in a rare blood disorder last month, argenx's Vyvgart Hytrulo missed its primary and secondary endpoints in a phase 3 in patients with two types of pemphigus.

104
104