Tue.Nov 28, 2023

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Early CT Screening Linked to Improved Lung Cancer Survival

Drug Topics

Although early computed tomography (CT) screening was associated with improved cure rate for patients with lung cancer, less than 6% of the population that is eligible receives it.

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Independent Rx Forum: NCPA Priorities, Legislative Updates for Independent Pharmacies

Pharmacy Times

Tune in to this episode of the Independent Rx Forum for a comprehensive overview of the National Community Pharmacists Association's legislative priorities, updates on critical pharmacy-related bills, and insights into the legislative process.

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STAT+: Mayo Clinic to spend $5 billion on tech-heavy redesign of its Minnesota campus

STAT

Mayo Clinic will spend $5 billion to reinvent its flagship medical campus in Rochester, Minn., infusing digital technologies into several new buildings designed to present a 21st-century vision of clinical care, the organization said Tuesday. The project, to include five new buildings with 2.4 million square feet of space, will merge Mayo’s traditional medical services with its increasing investments in artificial intelligence and digital tools.

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FDA investigates 'serious risk' of secondary cancer following CAR-T treatment

Fierce Pharma

In a blow to CAR-T therapies, the FDA is investigating a “serious risk” of patients developing new cancers after treatment with these highly efficacious oncology drugs. | In a blow to CAR-T therapies, the FDA is investigating a “serious risk” of patients developing new cancers after treatment with these highly efficacious oncology drugs.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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STAT+: FDA investigating whether CAR-T, a treatment for cancer, can also cause lymphoma

STAT

The Food and Drug Administration said Tuesday that it is investigating whether CAR-T therapy, which uses genetically modified white blood cells to attack tumors, can in rare cases cause lymphoma, a blood cancer. “Although the overall benefits of these products continue to outweigh their potential risks for their approved uses, FDA is investigating the identified risk of T cell malignancy with serious outcomes, including hospitalization and death, and is evaluating the need for regulatory

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Peanut Protein Therapy Provides Safe and Effective Treatment for Peanut-Allergic Children

Pharmacy Times

Peanut sublingual immunotherapy offers a practical treatment option for peanut-allergic toddlers, reducing symptoms in 80% of children.

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More Trending

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FDA Approves First Therapy for Rare Invasive Tumor Type With High Risk of Recurrence

Pharmacy Times

In a phase 3 trial, none of the patients receiving nirogacestat reached median progression-free survival, indicating that it may effectively reduce disease progression.

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STAT+: Biden invokes Defense Production Act to stem drug shortages

STAT

WASHINGTON — President Biden is using a Cold War-era law to stem drug shortages by boosting domestic pharmaceutical manufacturing. Biden announced the initiative at the first meeting of his supply chain resilience council. It’s based on a law, the Defense Production Act, that lets the government require private companies to make materials deemed necessary for national defense, in this case essential medicines and medical countermeasures.

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Pfizer takes Poland to court over alleged missed COVID-19 vaccine payments

Fierce Pharma

As the pandemic eased earlier this year, officials in Poland became vocal critics of the financial obligations laid down by Pfizer’s large vaccine supply pact with the European Union. | As the pandemic eased earlier this year, officials in Poland became vocal critics of the financial obligations laid down by Pfizer’s large vaccine supply pact with the European Union.

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STAT+: A growing number of U.S. states, cities, and counties are suing insulin makers and PBMs

STAT

In response to strained budgets, a growing number of state and local governments across the U.S. are suing insulin makers and pharmacy benefit managers over claims the companies conspired to illegally drive up prices. In recent weeks, state officials in Utah and Arizona , and municipalities in New York, Virginia , Maryland, and Ohio have filed lawsuits alleging that the companies artificially drove up the cost of insulin, making the medication unaffordable for countless residents who have diabet

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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Pharmaceutical Compounding, Storage of Faricimab Preserves Stability, Binding Properties

Drug Topics

Maintaining the structure and function of antibody biologics like faricimab is critical for their administration via intravitreal injection (IVI), a common treatment approach for retinal diseases.

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How to spot when drug companies spin clinical trial results

STAT

Investors , analysts, doctors, and even patients face an avalanche of news from biotech companies about their human trials of experimental drugs, and wading through all that data to draw reasonable conclusions is a challenging task. This week, STAT has published a 2023 update of its Guide to Interpreting Clinical Trial Results, which can help consumers of company readouts navigate the process.

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Gilead cuts 7% of staff at Kite Pharma unit as 'refreshed business strategy' introduced

Fierce Pharma

Gilead Sciences' Kite Pharma cell therapy unit is undergoing a business review that will result in layoffs to about 7% of the organization’s workforce. | Gilead’s Kite Pharma cell therapy unit is undergoing a business review that will result in layoffs to about 7% of the organization’s workforce. In a letter sent to staff this week that was obtained by Fierce Biotech, Kite Pharma Executive Vice President Cindy Perettie previewed a “refreshed business strategy” that would better align the un

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A nonprofit group is pushing to get estrogen FDA approved for gender-affirming care

STAT

Hormone replacement therapies have long been approved by the Food and Drug Administration for use by cisgender patients, such as women who take estrogen when going through menopause. Now, for the first time, a nonprofit group is pursuing research with the goal of FDA approval for the use of estrogen as a gender-affirming treatment for trans and gender-diverse patients.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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LinkedIn rolls out new features to help nurses, clinicians land their next job

Fierce Healthcare

Healthcare continues to be a hiring hotspot and LinkedIn aims to stay competitive as new staffing startups jump into the market. | Healthcare continues to be a hiring hotspot and LinkedIn aims to stay competitive as new staffing startups jump into the market.

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STAT+: Vertex pushes a donation program to widen access to cystic fibrosis treatments, but advocates say it’s not enough

STAT

Vertex Pharmaceuticals is being accused by a group of advocates and physicians of refusing to take several steps that would widen access to its pricey cystic fibrosis medicines in predominantly poor countries. In a recent Zoom call, company executives were urged to drop patent claims and implement a global pricing model reflecting R&D and production costs, which could make the treatments more affordable.

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Clinical Updates On COVID-19 Vaccine Options for Patients

Pharmacy Times

Regardless of which of these vaccines patients receive, as long as they receive them according to the prescribed schedules, they can protect themselves and their community against the COVID-19 virus.

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PCORI funds 4 new large studies focused on maternal health

Fierce Healthcare

The Patient-Centered Outcomes Research Institute (PCORI) has announced funding awards of $80.5 million to support four new studies focused on disparities in maternal health. | The studies will compare a range of practice-level and community- and home-based interventions to address common challenges in maternal health.

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Novartis dials up midterm sales projection, fleshes out Kisqali's $7B-plus goal

Fierce Pharma

Novartis is getting more optimistic about its midterm sales potential, thanks to bullish estimates for some blockbuster drugs. | Novartis is getting more optimistic about its midterm sales potential, thanks to bullish estimates for some blockbuster drugs, including Entresto and Kisqali.

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'Podnosis': Changing the game on kidney care

Fierce Healthcare

Chronic kidney disease is a significant public health issue. Nationwide, roughly 37 million Americans live with chronic kidney disease. | This week on "Podnosis," Senior Editor Heather Landi sits down with Misha Palecek, who leads DaVita’s strategic value-based care partnerships and care delivery innovations, to discuss why the shift to value-based care is critical in raising the bar on kidney care and addressing widespread healthcare disparities.

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After Cyfendus' full approval, Emergent clinches $75M anthrax vaccine supply pact in US

Fierce Pharma

Armed with a full FDA approval after four years supplying its anthrax vaccine under a pre-emergency use authorization, Emergent BioSolutions is expanding its countermeasure supply pact with the Uni | Armed with a full FDA approval after four years supplying its anthrax vaccine under a pre-emergency use authorization, Emergent BioSolutions is expanding its countermeasure supply pact with the United States.

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A Three Pronged Approach to Driving Purchasing Compliance Across Your Pharmacy

Drug Topics

Navigate drug shortages successfully! This white paper unveils a 3-step strategy, empowering your pharmacy against the impact of 301 active shortages. Learn from industry leaders, optimize vendor relationships and ensure uninterrupted patient care. Download now for resilience in pharmacy purchasing challenges.

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Why are my toes numb?

The Checkup by Singlecare

You sit cross-legged for too long, and that familiar feeling of pins and needles starts to creep in after your foot falls asleep. But what about a total loss of feeling, like numbness in the toes? Numb toes can happen for a variety of reasons. Sometimes, numbness in your toes is a temporary issue caused by ill-fitting shoes or spending too long out in the cold.

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Oral Immunotherapy for Common Food Allergies Receives FDA Fast Track Designation

Drug Topics

ADP101 is designed to treat allergy to 1 or more of the world’s most significant allergens including cashew, almond, chicken’s egg, cow’s milk, codfish, peanut, pecan, pistachio, salmon, sesame, soy, shrimp, walnut and wheat.

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Business Group on Health: 4 employer health trends to watch in 2024

Fierce Healthcare

Employers are going to be expecting more from their partners going into 2024 as they look to address issues ranging from mental health to drug costs to wellness. | Employers are going to be expecting more from their partners going into 2024 as they look to address issues ranging from mental health to drug costs to wellness.

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Study: Food Insecurity Associated With Increased Risk of Dementia

Pharmacy Times

Food insecurity was associated with an increased risk of dementia, poorer memory function, and faster memory decline in older adults.

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STAT+: Argenx antibody fails study in platelet-destroying autoimmune disorder, derailing expansion plans

STAT

Belgium drugmaker Argenx said Tuesday that its antibody medicine failed to achieve the goals of a late-stage study for a platelet-destroying autoimmune disorder — a setback in the company’s efforts to expand the drug’s use. Argenx shares were down 12% in early trading. The negative study, called ADVANCE-SC, was the second of two clinical trials involving the Argenx drug called efgartigimod in patients with primary immune thrombocytopenia (ITP), a debilitating condition that

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Adherence to Prevention Recommendations Associated With Reduced Risk For All Cancers

Drug Topics

The World Cancer Research Fund (WCRF) and American Institute for Cancer Research (AICR) Cancer Prevention Recommendations were updated in 2018 and encourage adopting healthy lifestyle habits.

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STAT+: White House official dings Bristol-Myers Squibb for fighting off generic competition

STAT

WASHINGTON — A top White House official on Tuesday delivered a pointed attack at a drugmaker fighting the administration’s Medicare negotiation plan in court. Christen Linke Young, White House Domestic Policy Council’s deputy assistant to the president for health and veterans affairs, took on Bristol-Myers Squibb, which makes the blockbuster blood thinner Eliquis.

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Dermavant CEO draws Botox comparison to instill Vtama confidence amid slow psoriasis uptake

Fierce Pharma

Dermavant CEO Todd Zavodnick isn’t concerned with the slow uptake of the hyped plaque psoriasis drug Vtama. He points to another breakthrough treatment which took a while to catch on: Botox. | Dermavant CEO Todd Zavodnick isn’t concerned with the slow uptake of hyped plaque psoriasis drug Vtama. He points to another breakthrough treatment which took a while to catch on—Botox.

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Medicaid navigation startup Fortuna Health picks up $4M backed by a16z, Cityblock founder and John Legend

Fierce Healthcare

Patients have to navigate too many hurdles when enrolling for and managing their Medicaid coverage. | Fortuna Health launched earlier this year to simplify Medicaid navigation. The startup picked up $4 million in seeding funding to accelerate state expansion. Here's why investors Andreessen Horowitz, Y Combinator and singer John Legend are backing the company.

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Biden looks to broaden HHS powers to bolster domestic drug manufacturing

Fierce Pharma

As drug shortages mount in the U.S. with little relief in sight, President Joe Biden has rolled out a slew of efforts to bolster the nation’s supply chains. | Monday, during the first meeting of the new White House Council on Supply Chain Resilience, President Biden unveiled nearly 30 actions to bolster production networks across industries. Among those actions, Biden intends to leverage the Defense Production Act (DPA) to make more essential medicines at home and thwart future drug shortages.

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Streamlined and tech-centric: eternalHealth hopes to stand out in health plan scene

Fierce Healthcare

Bringing luxury to healthcare without the luxury cost. That’s the stated mission of eternalHealth, a Medicare Advantage plan based in Massachusetts. | Upstart eternalHealth, backed by 26-year-old founder Pooja Ika and former Apple CEO John Sculley, sees opportunity to disrupt the Medicare Advantage landscape.

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Rite Aid pharmacists gain prescriptive authority for hormonal contraceptives in 5 states

Drug Store News

Pharmacists at select Rite Aid stores in California, Maryland, New Hampshire, Nevada and Oregon can now prescribe hormonal contraceptives, improving access for women in these states.

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