Mon.Aug 07, 2023

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Significant Association Found Between Vitamin D, Improved Insulin Resistance

Pharmacy Times

Researchers say vitamin D supplementation could be a low-cost and effective avenue for the reduction of insulin resistance and better outcomes in preventing and treating diabetes.

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A new study put period products through the wringer. Discs came out a winner

STAT

There are many period products on the market from pads, tampons and cups to discs. Yet, there is a dearth of reliable information about how much menstrual blood they can hold — a useful metric for clinicians as well as consumers. Heavy menstrual bleeding affects up to a third of people who menstruate and that can only be diagnosed using traditional menstrual products like pads and tampons.

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Clinical Trials Offer New Opportunities to Reshape the Future of Gastrointestinal Medicine

Pharmacy Times

New innovations are revolutionizing diagnostics and optimizing treatment outcomes, marking significant strides in the fight against digestive diseases.

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CMS again pauses out-of-network billing arbitration after judge sides with providers

Fierce Healthcare

The Centers for Medicare & Medicaid Services (CMS) has again suspended arbitration of out-of-network payment disputes between providers and payers due to a court order that the agency’s impleme | The Texas Medical Association scored another win against the administration's billing dispute resolution process in the district courts, this time successfully litigating against an administrative fee hike and requirements over which items could be jointly reviewed.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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FDA Approves First Oral Treatment for Postpartum Depression

Pharmacy Times

However, the FDA said an application for zuranolone to treat major depressive disorder did not provide substantial evidence of efficacy.

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Astellas wins FDA approval of eye disease drug Izervay and may have edge in market battle with Apellis

Fierce Pharma

Less than four months after Astellas’ $5.9 billion buyout of eye disease specialist Iveric Bio, the deal is already making the Tokyo-based company look visionary. | Less than four months after Astellas’ $5.9 billion buyout of Iveric Bio, the FDA has signed off on the main asset acquired in the deal, the geographic atrophy treatment Izervay.

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More Trending

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Kidney doctors push to protect patients by including dialysis machines in emergency stockpile

STAT

Ariel Brigham was drowning. Hurricane Harvey had dumped over 50 inches of rain across Houston and coastal Texas, leaving the then-26-year-old Texan stranded in her flooded apartment. But what was killing Brigham wasn’t water from the hurricane. It was the excess fluid and toxins building up in her own body.

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Here’s everything you should know about exercise during pregnancy

The Checkup by Singlecare

If you’re an expectant parent, especially a first-timer, you likely have many questions about what you should and shouldn’t do. For instance, can you work out during pregnancy? For parents-to-be who enjoy physical activity, you want to know how to safely exercise while providing the best prenatal environment for your baby. In the past, pregnant women were urged to decrease the intensity and length of exercise, but that’s evolving.

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Opinion: Doctors need to pay more attention to non-physical side effects of health care

STAT

When faced with a new diagnosis, a patient knows that the necessary treatment may make her feel lousy. What she doesn’t always account for, though, is the effect that it will have on the rest of her life. It’s common for patients and physicians to decide whether a treatment is worth it by weighing the health benefits against the side effects.

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Biogen, Sage's postpartum depression approval overshadowed by larger rejection

Fierce Pharma

While an FDA approval is typically cause for celebration, Sage Therapeutics and Biogen have a tough road ahead to market their new postpartum depression (PPD) drug. | Friday, the U.S. FDA gave the green light to zuranolone. Now going by the commercial moniker Zurzuvae, the partners’ drug represents the first and only oral treatment for women with PPD, which affects some 500,000 patients in the U.S. each year, according to Biogen and Sage.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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Community health workers, experts in the in-between, fight for their place in the system

STAT

NEW YORK — A nurse supervisor at Montefiore Comprehensive Health Care Center in the Bronx was delivering her start-of-shift updates and mantras — “Covid is not finished with us … clean, clean, clean!”— to the clinicians and administrative staff bunched up nearby. Hawa Abraham, not one or the other, stood among them.

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Doubling Down on Drug Adherence

Pharmaceutical Commerce

Creating a user-centric approach that harnesses both digital tools and behavioral science is key to getting—and maintaining—patients on therapy, and improving clinical, financial, and, ultimately, brand-success outcomes for pharma manufacturers.

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Attacks at US medical centers show why health care is one of the nation’s most violent fields

STAT

Word spread through an Oregon hospital last month that a visitor was causing trouble in the maternity ward, and nurses were warned the man might try to abduct his partner’s newborn. Hours later, the  visitor opened fire, killing a security guard  and sending patients, nurses and doctors scrambling for cover.

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DE&I Accountability in Pharma

PharmExec

Rebekah Martin, senior VP of reward, inclusion, and talent acquisition at AstraZeneca, discusses ways companies can remain accountable for DE&I efforts in pharma in this Pharmaceutical Executive Podcast video.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Clover Health avoids potential Nasdaq stock delisting

Fierce Healthcare

Medicare Advantage-focused insurtech Clover Health has staved off a potential delisting of its stock. | Medicare Advantage-focused insurtech Clover Health has staved off a potential delisting of its stock.

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Trifluridine/tipiracil approved in Europe and US for metastatic colorectal cancer

Hospital Pharmacy Europe

Trifluridine/tipiracil (Lonsurf) has received approval for use in combination with bevacizumab from the European Commission and the FDA for the treatment of adult patients with metastatic colorectal cancer. Eligible patients will have received two prior anti-cancer treatments including fluoropyrimidine-, oxaliplatin- and irinotecan-based chemotherapy, an anti-VEGF biological therapy, and if RAS wild-type, an anti-EGFR therapy.

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Ongoing cyberattack on Prospect Medical Holdings forces facilities offline, disrupts services

Fierce Healthcare

Prospect Medical Holdings was hit with a cyberattack last week that brought computer systems offline and continues to disrupt care in certain areas. | An outage disclosed Thursday is affecting facilities across the holding company's 16-hospital footprint. Some representatives at affiliate systems have describe the incident as a ransomware attack.

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Pharmacy services in emergency departments: a comprehensive approach to improve patient care

Hospital Pharmacy Europe

With the experiences, skillsets and expectations of pharmacists working in emergency departments varying across Europe, finding a consensus on the detail and extent of their involvement is complex. But now, a group of Spanish pharmacists and emergency medicine specialists have issued a joint declaration to streamline understanding and improve patient care.

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Opinion: Drugs alone can’t win the war against tuberculosis

STAT

Recently, after years of pressure, advocates including author and philanthropist John Green scored victory against Johnson & Johnson over a patent on a key tuberculosis drug. The campaigners hope the move will give millions of people affected by tuberculosis in low- and middle-income countries access to the lifesaving medication bedaquiline. But the drugs alone can’t win the fight against the debilitating disease.

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Half the world’s population will have a mental health disorder by age 75

Hospital Pharmacy Europe

One in two people will develop a mental health disorder in their lifetime, with depression and anxiety being the most common illnesses, new research suggests. The global study, which involved over 150,000 participants across 29 different countries, found that most mental health disorders first emerge in adolescence, highlighting the importance of investing in mental health services for young people.

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STAT+: Pharmalittle: FDA OKs Sage drug for postpartum depression; major U.S. health systems to offer Alzheimer’s drug

STAT

Good morning, everyone, and welcome to another working week. We hope the weekend respite was invigorating and refreshing, because that oh-so familiar routine of online meetings, calls, and deadlines has predictably returned, But what can you do? The world, such as it is, continues to spin. So to cope, we are brewing cups of stimulation — our choice today is cinnamon hazelnut.

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Alignment Health CEO offers look at its medical benefits ratio strategy

Fierce Healthcare

Medicare Advantage plan Alignment Healthcare is targeting significant improvements to its medical benefits ratio heading into 2024, and the company's top brass offered investors a look at its strat | Medicare Advantage plan Alignment Healthcare is targeting significant improvements to its medical benefits ratio heading into 2024.

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WHO adds cardiovascular polypill to List of Essential Medicines

Hospital Pharmacy Europe

The World Health Organization (WHO) has added a cardiovascular polypill, which includes acetylsalicylic acid, ramipril and atorvastatin, to its List of Essential Medicines. Developed by the Spanish National Centre for Cardiovascular Research (CNIC ) in conjunction with the Ferrer Foundation , the cardiovascular polypill has been proven to be effective in preventing cardiovascular events after a heart attack.

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Kellogg, Meijer celebrate young Black farmers making an impact in Michigan

Drug Store News

​​​​​​​For a fifth year, Kellogg's "Rooted in the Midwest" campaign supports, encourages and recognizes farmers in the region through donations and employee volunteering.

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Cytisine may offer viable alternative to varenicline for smoking cessation

Hospital Pharmacy Europe

With varenicline currently unavailable, it is possible that cytisine might serve as an alternative pharmacotherapy to help patients to stop smoking. Smoking has wide-reaching adverse health effects and is a major cause of premature death, yet some eight million people across the world die every year due to the effects of smoking. Smoking cessation aids such as varenicline are effective at increasing smoking quit rates, but this drug is currently unavailable in both Europe and the UK due to the p

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First ever pill for postpartum depression from Biogen Inc. and Sage Therapeutics approved by FDA

Outsourcing Pharma

The first oral pill in the United States specifically for postpartum depression, a serious mental illness, has been approved by the US Food and Drug Administration (FDA).

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STAT+: Sage considers ways to reduce costs following FDA rejection on drug for major depression

STAT

Sage Therapeutics said Monday that it may need to reduce costs, including through employee layoffs, following the Food and Drug Administration’s denial of its rapid-acting drug for major depressive disorder. On Friday, the agency granted market clearance for the drug , called Zurzuvae, to treat women with postpartum depression, a smaller commercial market.

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Dupilumab Effective for Patients With Bullous Pemphigoid

Drug Topics

A recent study found that 4 weeks of treatment with dupilumab led to 87% of patients achieving disease control.

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HRG’s five notable products from July 2023

Drug Store News

HRG reviewed 43 products in the health category, 85 items in the wellness sector and 41 items in the beauty aisle to see which ones stood out as Products to Watch.

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Echoing Pfizer, BioNTech says it's 'carefully watching' costs as COVID vaccine sales sink

Fierce Pharma

As Pfizer eyes possible cost cuts, its COVID vaccine partner BioNTech is “carefully watching” its spending, the German company’s finance chief Jens Holstein

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Pharma’s rocky love affair with oxytocin

PharmaVoice

Although research on using oxytocin as a drug has varied, Tonix Pharmaceuticals is banking on the “love hormone” to treat autism, anxiety and more.

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Astellas to advance oncology CAR-T therapy

European Pharmaceutical Review

Astellas Pharma has agreed to invest a total of $50 million for the right to license P-MUC1C-ALLO1, an allogeneic CAR-T cell therapy in development for multiple solid tumour indications. Under the agreement, the company will acquire approximately 8.8 percent of Poseida Therapeutics. Astellas Pharma will receive a right of exclusive negotiation and first refusal for any potential partnering of P-MUC1C-ALLO1.

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After similar moves in Kenya and India, GSK telegraphs commercial halt in Nigeria

Fierce Pharma

After charting a similar move in Kenya last year, GSK is pulling the plug on its Nigerian operations. | GSK said it plans to cease commercialization of its prescription medicines and vaccines in Nigeria, with the intent to switch to a third-party direct distribution model. GSK’s consumer health spinoff Haleon is taking similar steps, too.

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STAT+: Nektar Therapeutics sues Lilly for ‘misconduct’ in drug development deal

STAT

A behind-the-scenes feud over a drug development program erupted into public view as Nektar Therapeutics filed a lawsuit accusing Eli Lilly of undermining a project in favor of another deal. At issue is a partnership that began in 2017 to develop and potentially market a drug, known as Rezpeg, to treat various autoimmune diseases, and in particular, eczema.

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