Wed.Jan 31, 2024

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Recurrent C difficile Infection Prevention: Efficacy and Administration of Fecal Microbiota Therapy

Pharmacy Times

Sharon Rimon, NP, shares insights on the rectal administration of fecal microbiota therapy, highlighting its efficacy, ease of adoption in clinical practice, and benefits for patients.

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Pregnant Women With Diabetes at Increased Risk of Anxiety, Depression

Drug Topics

A recent study found that patients with pre-gestational diabetes reported higher levels of both borderline and abnormal anxiety compared to patients with gestational diabetes.

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Some dementia patients might have reversible symptoms caused by cirrhosis, study says

STAT

The descent into dementia can feel like traversing a minefield, coming across new symptoms without the hope of a cure. But some dementia patients, even up to 10% of people diagnosed with the condition, might actually have undiagnosed liver disease and accompanying neurological problems, a new study in JAMA Open Network suggests. Most importantly, it’s possible their liver-related brain symptoms could be resolved with treatment.

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Pharmacists' Patient Counseling Role

Pharmacy Times

Kristen Peterson, PharmD, BCOP, explores how pharmacists deliver comprehensive education, empower patients, manage side effects, and prioritize outcomes for multiple myeloma care, ensuring quality treatment understanding and adherence.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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STAT+: Judge skeptical of arguments against Medicare drug price negotiation

STAT

WILMINGTON, Del. — Wednesday was the first time that a federal judge asked questions in-person of drug industry lawyers who are trying to stop Medicare from negotiating drug prices. It didn’t go well for them. AstraZeneca’s lawyers argued that Medicare’s new powers amount to a taking of their property rights without due process.

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Biogen abandons Aduhelm efforts, focuses on Eisai-partnered Leqembi and pipeline drugs

Fierce Pharma

More than two years after Aduhelm's controversial and ill-fated FDA accelerated approval, Bi | Biogen is discontinuing its first Alzheimer's disease therapy, Aduhelm, after walking a rocky path. The company is taking a $60 million charge, halting sales and terminating a confirmatory trial.

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GSK confirms Arexvy is a blockbuster but says the RSV battle has just begun

Fierce Pharma

Beaten to the punch by Pfizer in developing a vaccine for COVID, GSK has regained some of its lost luster as a vaccine powerhouse with its advancement of respiratory syncytial virus (RSV) shot Arex | GSK's RSV vaccine Arexvy generated $1.5 billion in sales in 2023 compared to $890 million for Pfizer's Abrysvo. But the British pharma major says that the successful launch represents just one round of a boxing match, and much is still to be decided, especially with Moderna expected to joi

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Cigna to sell Medicare Advantage plans to Blue Cross Blue Shield insurer for $3.3 billion

STAT

Cigna is officially exiting the Medicare business, agreeing to sell all of its Medicare insurance plans to Health Care Service Corp., a large Blue Cross Blue Shield insurer, for $3.3 billion. The deal includes Cigna’s 600,000 Medicare Advantage plan members, as well as all Medicare beneficiaries who have a Medicare prescription drug plan and Medigap plan through Cigna.

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Cigna inks deal to sell Medicare business to HCSC for $3.7B

Fierce Healthcare

Cigna will sell off its Medicare business to Health Care Service Corporation in a deal valued at $3.7 billion, the company announced Wednesday. | HCSC will acquire Cigna's Medicare Advantage, Part D, supplemental benefits and CareAllies businesses, and the parties expect the deal to close in the first quarter of 2025.

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Opinion: The Biden administration should not support a WTO petition to strip IP protections from Covid-19 treatments

STAT

The Biden administration may soon double down on one of its gravest mistakes. In 2022, it supported a petition before the World Trade Organization to gut intellectual property protections for Covid-19 vaccines. Now, with the WTO planning to take up the issue again in late February, the administration must decide whether to support a similar proposal that would strip protections from Covid-19 treatments and diagnostics as well.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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Payers up against slight decline in 2025 Medicare Advantage payments

Fierce Healthcare

Medicare Advantage (MA) payments are set to decrease yet again in 2025 as the feds phase in significant changes to risk adjustment. | Medicare Advantage payments are set to decrease yet again in 2025 as the feds phase in significant changes to risk adjustment.

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STAT+: As supply crunch starts to ease, Novo Nordisk to offer more doses of obesity drug Wegovy to U.S. patients

STAT

LONDON — Novo Nordisk said Wednesday that it had started to increase the availability of its blockbuster obesity drug Wegovy for new patients in the United States, after massive demand and a supply crunch had led it to limit such doses last May. The announcement that Novo was making more of its lower-dose starter product available as of this month came as the company reported its 2023 earnings, with sales up by 36% and operating profit up 44% at constant exchange rates, driven by massive

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Fostering Equity in Health Care Research: Eliminating Gender Bias With Decentralized Clinical Trials for Women

Pharmacy Times

Decentralized clinical trials are emerging as a method by which to address gender bias in clinical research.

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Opinion: What the pope is missing about commercial surrogacy

STAT

Over the past few years, I have watched a wonderful young boy I’ll call Chad grow up smart and full of life. His parents, a gay couple with whom I am friends, used a gestational surrogate, Mary (also a pseudonym), a kind, down-to-earth woman whom I have also met. I have been thinking of him recently when I read Pope Francis’  recent comments about surrogacy.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Telehealth & AI: Enhancing Accessibility and Continuity in Patient Care

Pharmacy Times

The transformation brought about by these technologies is akin to a revolution in health care.

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JP Morgan 2024 – Gene Kinney

pharmaphorum

In this exclusive interview, Gene Kinney, CEO of Prothena, discusses the latest developments in the field of neurodegenerative diseases such as Alzheimer's and Parkinson's. Gain insights and advancements being made in the treatment of these conditions.

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Pharmacists’ Responses in Medical Emergencies Highlight Need for Provider Status

Pharmacy Times

On a flight home from ASHP Midyear in December, one pharmacist stepped up to the plate in a medical emergency.

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STAT+: Obscure vertigo drug could bring rare hope for patients with devastating neuron disease

STAT

About a decade ago, Tatiana Bremova-Ertl’s graduate adviser was studying an obscure, 1950s-era French vertigo drug, probing its effects on people with balance disorders, when she thought of another, very sick group of patients.  A graduate student and medical resident at the German Center for Vertigo and Balance Disorders, in Munich, Bremova-Ertl often saw patients with Niemann-Pick Type C, a rare, genetic disease that slowly kills neurons.

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Provider groups, bipartisan lawmakers rally around bills supporting healthcare worker safety, mental well-being

Fierce Healthcare

Provider groups and the legislative allies took to the field this week to drum up more support for bills designed to protect the healthcare workforce’s physical and mental well-being. | While some legislators headed an industry-backed briefing for the SAVE Act, others introduced a reauthorization of the Dr. Lorna Breen Health Care Provider Protection Act.

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The secret to successful patient influencer marketing? Authenticity

pharmaphorum

Reverba offers innovative patient engagement solutions and strategies that utilise the power of authentic patient influencers. Discover the secret to successful patient influencer marketing and how it can benefit your healthcare organisation.

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Telenutrition provider Foodsmart raises $10M, announces health systems rolling out food prescriptions

Fierce Healthcare

Foodsmart, a telenutrition company, has onboarded three new health system partners and announced additional funding to roll out its food prescription program known as Foodscripts. | Foodsmart aims to simplify the process for doctors to refer patients with chronic conditions to dietitians to access quality food via what’s known as Foodscripts. Like a pharmacy prescription, patients get a Foodscript, or referral to Foodsmart dietitians, who offer subsidized meals tailored to a given condition.

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STAT+: Experts critique flawed system for monitoring drugs’ side effects in wake of asthma drug report

STAT

After a drug enters the market, it’s up to Food and Drug Administration regulators to ensure its continued safety and efficacy. A recent New York Times story suggests that, in the case of the popular asthma drug Singulair, the FDA fell short — both because the agency delayed action for years on reports from patient advocates and independent groups that the drug could cause suicidal thoughts, and because when it did add a warning label about its potential side effects in 2020, clini

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Cardinal Health to acquire Specialty Networks and its PPS Analytics platform

Drug Store News

The transaction creates increased clinical and economic value for 11,500 specialty providers, including more than 7,000 physicians across 1,200 independent physician practices

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AbbVie’s Tepkinly backed by NICE for DLBCL patients

pharmaphorum

AbbVie’s CD20xCD3 bispecific antibody Tepkinly has been recommended by NICE for NHS use as a treatment for relapsed or refractory diffuse large B-cell lymphoma (DLBCL), an aggressive and fast-growing form of non-Hodgkin lymphoma. Tepkinly (epcoritamab) – the first medicine to emerge from AbbVie’s $3.9 billion alliance with Genmab signed in 2020 – can be used to treat adults with DLBCL whose cancer has returned or has not responded to at least two previous systemic treatments.

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Novo Nordisk doubles stock of Wegovy starter doses but supply constraints persist: CEO

Fierce Pharma

Even with a competitor’s drug now on the scene, Novo Nordisk is aiming for another year of dominance in the obesity arena thanks in large part to a resupply of starter doses of the company’s weight | Even with a competitor’s drug now on the scene, Novo Nordisk is aiming for another year of dominance in the obesity arena.

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6 prednisone side effects in women

The Checkup by Singlecare

Prednisone is a corticosteroid that reduces inflammation in the body. It’s used to treat many medical conditions, including asthma, certain types of cancer, rheumatoid arthritis, blood conditions, lupus, and immune system disorders. It’s well known that prednisone can have unwanted side effects , such as headaches, insomnia, irritability, dry and thinning skin, weight gain, and swelling of the legs and face.

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Teva's refresh under new CEO Francis moves into year 2 as Austedo, Ajovy and generics gain steam

Fierce Pharma

After charting a series of sales increases in 2023, Teva’s largely made good on the promise of its new CEO’s “Pivot to Growth” campaign. | After charting a series of sales increases in 2023, Teva’s largely made good on the promise of its new CEO’s “Pivot to Growth” campaign. With group revenues on the up-and-up, it’s all about maintaining momentum in the years to come, the company’s chief executive Richard Francis said in an interview.

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Novartis calls time on Tim3 drug sabatolimab in MDS

pharmaphorum

Novartis ends development of Tim3 antibody sabatolimab in myelodysplastic syndromes after failed phase 3 trial.

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Pharmacist Spotlight: Jessica Hung, PharmD

Pharmacy Times

This month’s pharmacist spotlight features Jessica Hung— pharmacist at an independent pharmacy in Alabama

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Daiichi Sankyo again dials up Enhertu sales forecast, advances 2nd AstraZeneca-partnered ADC

Fierce Pharma

AstraZeneca-partnered Enhertu has become a bright spot in Daiichi Sankyo’s business, and the Japanese pharma has again increased its sales projection for the HER2-directed antibody-drug conjugate.< | AstraZeneca-partnered Enhertu has become a bright spot in Daiichi Sankyo’s business, and the Japanese pharma keeps increasing its sales projections for the HER2-directed antibody-drug conjugate.

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Immunotherapy changed the cancer treatment landscape. Is the gut microbiome the next frontier?

PharmaVoice

The president of L.A.’s City of Hope Cancer Center believes the current state of cancer treatments can be greatly improved with a peek into the gut’s many mysteries.

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12 health benefits of papaya

The Checkup by Singlecare

Papaya (Carica papaya), also called pawpaw, is a large, oblong tropical fruit with smooth skin and sweet flesh. It’s cultivated in many parts of the world, including India, Brazil, Indonesia, Nigeria, and Mexico—along with Hawaii, California, Texas, and Florida in the United States. Papayas are a superfood—they are low in calories and rich in nutrients like vitamins A, C, and E.

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Biogen Ends Development, Sales of Aducanumab for Alzheimer Disease

Drug Topics

After facing challenges, Biogen is discontinuing development and sales of aducanumab (Aduhelm) and focusing on lecanemab (Leqembi).

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Why is asthma worse at night?

The Checkup by Singlecare

Getting a good night’s sleep is vital to staying healthy, both physically and mentally. But, that can be hard if you’re up all night coughing and wheezing. “Nocturnal asthma” is when you experience a flare-up of asthma symptoms overnight. It can lead to a loss of crucial shuteye and exacerbate daytime asthma. Much like daytime asthma, common symptoms of nocturnal asthma include coughing, wheezing, shortness of breath, and chest tightness.

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