Fri.Sep 29, 2023

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Pharmacists Work to Sustain Care in Health Care Deserts

Drug Topics

When rural areas lose hospitals and primary care clinics, residents must turn to pharmacies to receive the care they need.

Hospitals 261
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Lead Investigator Provides Insight Into FDA Approval of Momelotinib for Myelofibrosis

Pharmacy Times

Ruben A. Mesa, MD, FACP, discusses the results of the SIMPLIFY-1 and MOMENTUM trials and how the data led to the approval of momelotinib to treat intermediate or high-risk myelofibrosis in adult patients with anemia.

FDA 145
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CVS Implements Measures to Improve Working Conditions After More Kansas City Pharmacists Stage Walkouts

Drug Topics

After several walkouts protesting poor working conditions, company executives and protest organizers came to an agreement that includes more hours for technicians and vaccinations being reduced to a manageable volume.

Vaccines 201
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Bridging the Gap: Industry-Academia Collaboration in Pharmacy

Pharmacy Times

The most persuasive reason for industry-academia collaboration is the many opportunities it opens for pharmacy students who may not have considered all the ways they can use their PharmD to serve the cause of humankind.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Independent Pharmacies Say They Can Help Patients Impacted by Chain Store Closures, NCPA Survey Finds

Drug Topics

A new poll from the organization surveyed 10000 independent community pharmacy owners on current worries in the industry and how they are being impacted by the ongoing national drug shortage.

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WHO recommends dropping component of many flu vaccines

STAT

The World Health Organization has recommended dropping a component of many flu vaccines because the viruses it protects against appear to have been driven into extinction in the Covid-19 pandemic. A family of viruses known as influenza B/Yamagata has not been seen since March 2020, when flu circulation worldwide declined to very low levels in the face of the onslaught of Covid and the protections people took to avoid contracting it.

Vaccines 145

More Trending

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Women spend 20% more per year on out-of-pocket health costs, says report

STAT

Women of all ages pay a total of $15.4 billion more than men on annual out-of-pocket medical expenses, according to a new report from Deloitte. In 2021, that meant that women paid about 20% more than men — only 2% of which could be accounted for by maternity care. The fact that the way benefits are currently designed “puts a disproportionate cost on women, above and beyond maternity, was the thing that really surprised us,” said Kulleni Gebreyes, a physician who runs Deloitt

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Topline Data Demonstrate Survival Improvement With Amivantamab-vmjw for NSCLC

Pharmacy Times

The MARIPOSA study evaluated amivantamab-vmjw (Rybrevant; Janssen Pharmaceutical) in combination with lazertinib compared to osimertinib and compared to lazertinib monotherapy in the first-line treatment of EGFR-mutated non–small cell lung cancer.

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Dianne Feinstein’s struggle with shingles reflects the long increase in cases

STAT

The trailblazing life of Senator Dianne Feinstein of California, who died on Friday, covers nearly a century of American history, including changes in health care and medicine. Her struggle with shingles, which sent her to the hospital in February and contributed to the deterioration of her health — leading to encephalitis and facial paralysis — also reflects the great shifts regarding that disease.

Hospitals 140
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Eli Lilly moves to settle with whistleblower who flagged alleged manufacturing shortfalls

Fierce Pharma

After a former human resources officer blew the whistle on alleged manufacturing shortfalls at Eli Lilly’s massive Branchburg, New Jersey, production plant, the parties have been engaged in settlem | After a former human resources officer blew the whistle on alleged manufacturing shortfalls at Eli Lilly’s massive Branchburg, New Jersey, production plant, the parties have been engaged in settlement talks.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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STAT+: Taysha Gene Therapies’ plan to tackle rare diseases is crumbling

STAT

In 2020, as biotech stocks surged amid the pandemic, a startup called Taysha Gene Therapies raised over $300 million off an audacious promise: It was going to license and develop gene therapies for at least 18 different rare and serious neurological diseases. The effort brought hope for many rare disease families, some of whom had raised money to fund the UT-Southwestern scientist who designed the treatments after they saw no other options for their children.

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Medicare enrollment begins in 2 weeks. Here's what major payers are offering for 2024

Fierce Healthcare

The industry is just two weeks away from the beginning of Medicare's annual enrollment period, a critical window for the hottest market in insurance. | The industry is just two weeks away from the beginning of Medicare's annual enrollment period, a critical window for the hottest market in insurance.

Insurance 121
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STAT+: Sales from controversial drug discount program rose to $54 billion last year

STAT

Prescription medicines purchased in the U.S. under a controversial government discount program amounted to $53.7 billion in 2022, an 18% increase from the previous year, according to the U.S. Health Resources & Service Administration, which oversees the program. The latest data mark a steady rise in sales under the 340B Drug Discount Program, which requires drugmakers to offer discounts that are typically estimated to be 25% to 50% — but could be higher — of all outpatient drug

Hospitals 118
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In label expansion bid, AbbVie and Roche's Venclexta falls short in multiple myeloma subset

Fierce Pharma

After establishing Venclexta as a treatment for chronic lymphocytic leukemia (CLL) and acute myeloid leukemia (AML), AbbVie and Roche were hoping to demonstrate the med's promise in a subset of mul | Despite the trial missing its primary endpoint of progression-free survival, the companies will soon discuss the "potential favorable trends" with health authorities.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Insurers argue that they're not to blame for snags in COVID-19 vaccine rollout

Fierce Healthcare

Major payers promised to iron out snags involved in the rollout of the ne | Insurers cite some obstacles not in their control that contributed to problems with the rollout of the new COVID-19 vaccine.

Insurance 117
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Opinion: AI-driven data analysis could exacerbate misaligned incentives in biomedical research

STAT

This summer OpenAI released Code Interpreter , a plug-in for the popular ChatGPT tool that allows it to take in datasets, write and run Python code, and “ create charts, edit files, perform math, etc. “ It aims to be nothing short of the ideal statistical collaborator or research software engineer, providing the necessary skill and speed to overcome the limitations of one’s research program at a fraction of the price.

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Researchers Reframe the Definition of Clinical Remission for Asthma

Pharmacy Times

A workgroup of asthma treatment experts introduced 6 new criteria that those diagnosed with asthma must meet to be in remission.

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STAT+: Unitaid slams J&J over pricing and patents for a tuberculosis drug

STAT

In a highly unusual move, Unitaid has publicly criticized Johnson & Johnson over its pricing and patenting policies for a key drug used to combat tuberculosis. The global health organization released a letter urging the company to drop so-called secondary patents for its medicine, known as bedaquiline, and to make negotiated prices for the drug available to all countries, regardless of existing arrangements for making purchases.

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Study Finds Individuals Prefer PrEP Over Other HIV Prevention Methods

Pharmacy Times

Individuals taking HIV prevention prefer the PrEP oral daily dose compared to new treatment methods.

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Proposed chemical ban would cause EU drug manufacturing to 'grind to a halt,' trade group warns

Fierce Pharma

A proposed restriction on the use of fluorinated substances in Europe would have an “irredeemable impact” on the continent’s life sciences sector, the European Federation of Pharmaceutical Industri | A proposed restriction on the use of fluorinated substances in Europe would have an “irredeemable impact” on the continent’s life sciences sector, the European Federation of Pharmaceutical Industries and Associations (EFPIA) warns.

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Analysis Indicates Sleep Duration, Health Influenced by Environmental Changes

Pharmacy Times

Environmental factors may change sleep patterns over time, which subsequently affects rapid eye movement sleep.

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STAT+: Generic makers fall short when providing access to low- and middle-income countries, analysis finds

STAT

A handful of the largest purveyors of generic medicines have made only halting progress to ensure their drugs are accessible for patients in low- and middle-income countries, a new analysis found. For instance, just one of 50 different treatments marketed by these companies — Teva Pharmaceuticals, Sun Pharmaceutical, Cipla, Hikma Pharmaceuticals, and Viatris — had a pricing strategy in place that considered a patient’s ability to pay.

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Incidence of Type 2 Diabetes Increased Significantly Following COVID-19 Pandemic

Pharmacy Times

Investigators also found that rates of type 1 diabetes have been on the rise since 2016.

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Chemo-free regimen demonstrates efficacy in NSCLC

European Pharmaceutical Review

Janssen Pharmaceutical Companies of Johnson & Johnson’s Phase III MARIPOSA study is the first to show a clinically meaningful benefit in a chemotherapy-free regimen compared to the small molecule treatment TAGRISSO ® ( osimertinib ). This is based on positive topline results for Rybrevant ® (amivantamab-vmjw) in combination with lazertinib, as first-line anti-cancer treatment in locally advanced or metastatic EGFR-mutated non-small cell lung cancer (NSCLC).

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Independent Pharmacies Take Center Stage at AAP’s Annual Conferences

Drug Topics

Guests who attend the 2024 American Associated Pharmacies Annual Conference can win up to $25,000 in credit at the API Warehouse.

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Discounted drug purchases under 340B grew 22% to $54B across 2022, HRSA reports

Fierce Healthcare

Discounted prescription drugs purchased wholesale under the 340B program grew 22.3% to $53.7 billion from 2021 to 2022, accordin | The latest report of rising discount drug purchases comes amid Congressional scrutiny on how participating hospitals are opting to use their savings.

Hospitals 102
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Teva continues its transformation, hiring Christine Fox to take over US business

Fierce Pharma

Teva CEO Richard Francis has continued his transformation of the company, bringing on Christine Fox as the new head of its U.S. commercial business.

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AI-supported spectroscopy delivers superior pharmaceutical packaging QC

European Pharmaceutical Review

A paper published in the IEEE Sensors Journal has demonstrated 100 percent inline pharmaceutical packaging content verification by combining standard diffuse reflectance MOEMS-EC-QCL spectroscopy with artificial intelligence (AI). It described how a quantum cascade laser (QCL)-based blister-verification sensor with verification via backscattering mid-infrared (IR) spectroscopy substance chemical identification can support blistering machines to achieve a better inline content verification.

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Innovative Solutions in Medication Packaging Can Improve Adherence

Drug Topics

Near-field communication (NFC)-enabled medication blister packaging can help patients improve their medication adherence.

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Karuna Therapeutics files for FDA approval for schizophrenia treatment

Pharmaceutical Technology

Karuna Therapeutics has announced the submission of a NDA to the FDA for KarXT (xanomeline-trospium) for the treatment of schizophrenia.

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FDA approves first-in-class antidepressant

European Pharmaceutical Review

The US Food and Drug Administration (FDA) has approved Exxua (gepirone hydrochloride extended-release tablets) for adults with major depressive disorder ( MDD ). Oral selective serotonin (5HT) 1a receptor agonist Exxua is the first approved antidepressant with a novel mechanism of action that selectively targets the serotonin 1A receptor, a key regulator of mood and emotion.

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Industry Voices—The evidence is mounting: Better care actually does cost less

Fierce Healthcare

Conversations about providing better healthcare often focus on new diagnostic technologies, groundbreaking clinical procedures, or other transformative innovations in the hospital setting. | Technological advances are certainly important, but they often overlook the importance of addressing whole-person care in the home and the community.

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NCPA applauds class action lawsuit against PBMs to recoup DIR fees

Drug Store News

The lawsuit claims that Caremark has been assessing pharmacy DIR fees in violation of federal antitrust laws and state laws governing contracts.

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STAT+: Up and down the ladder: The latest comings and goings

STAT

Hired someone new and exciting? Promoted a rising star? Finally solved that hard-to-fill spot? Share the news with us, and we’ll share it with others.   That’s right. Send us your changes, and we’ll find a home for them. Don’t be shy. Everyone wants to know who is coming and going. And here is our regular feature in which we highlight a different person each week.

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