Thu.Oct 12, 2023

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Fostamatinib Reduces Reliance on Oxygen in Severe COVID-19 Cases

Drug Topics

A study presented at IDWeek 2023 showed significantly more patients in the treatment group were alive and oxygen-free by day 29 and day 60 compared to those in the placebo group.

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FDA Approves Encorafenib Plus Binimetinib Combination for Non-Small Cell Lung Cancer

Pharmacy Times

Encorafenib (Braftovi; Pfizer Inc) and binimetinib (Mektovi; Pfizer Inc) approved for the treatment of patients with metastatic non-small cell lung cancer who harbor a BRAF V600E mutation.

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Trending Sources

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Treating Rural America: The new country doctors

STAT

Family medicine physician Olusunmisola Oyesiku always thought she would practice in a big city, but after going through her family residency program at the University of Alabama in Selma, she ended up falling in love with rural medicine. The Selma program is one of a small, but growing, number of residencies in the country that places residents entirely in rural medical settings.

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Why One Medical's CMO believes Amazon Health can make a big impact tackling chronic diseases

Fierce Healthcare

Amazon’s $3.9 billion acquisition of One Medical made big waves when it was announced in July 2022, signaling that the online retailer had bold ambitions to expand its reach in healthcare. | One Medical CMO Dr. Andrew Diamond is bullish about what Amazon is building in healthcare. He believes Amazon Health can help tackle the burden of chronic diseases in the U.S.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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STAT+: Peter Marks on creating Operation Warp Speed, but for rare diseases

STAT

Peter Marks wants drug developers to ask more stupid questions.  It’s part of the top Food and Drug Administration official’s plan to reinvigorate gene therapy, a field that has struggled despite significant technological advances. Some companies are shelving programs or going out of business , even when they have promising data.  The problems are numerous : The diseases are often exceptionally rare, limiting the potential market.

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Walgreens to close 60 VillageMD clinics as part of aggressive cost-cutting strategy

Fierce Healthcare

Drugstore chain Walgreens plans to close 60 underperforming VillageMD clinics and exit five markets as part of an aggressive $1 billion cost-saving strategy as it looks to boost profitability in it | Drugstore chain Walgreens plans to close 60 underperforming VillageMD clinics and exit five markets as part of an aggressive $1 billion cost-reduction strategy as it looks to boost profitability in its healthcare business.

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More Trending

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TikTok Videos About Pap Smears Could Encourage More Women to Get Screened for Cervical Cancer

Drug Topics

Videos on the social media platform where doctors used supportive language were found to improve attitudes towards Pap smears the most, a new study found.

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STAT+: EU orders Illumina to divest cancer diagnostics firm Grail

STAT

LONDON — European regulators on Thursday detailed their demands that Illumina divest the cancer diagnostics firm Grail, the latest fallout from the sequencing giant’s troubled 2021 acquisition. The move was just the most recent regulatory action against the deal. The European Commission in September 2022 ruled that the purchase violated antitrust rules, and Thursday’s order spelled out how the commission thought the deal’s unraveling should occur.

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FTC is full-steam ahead on sweeping noncompete ban, reinforcing antitrust, agency head tells docs

Fierce Healthcare

Healthcare lobbying organizations’ efforts to carve out industry-specific exemptions in recently proposed Federal Trade Commission (FTC) policies are unlikely to see their requests reflected in the | FTC Chair Lina Khan told a conference of physicians that the proposal for a broad ban on non-compete clauses was largely supported in public comments, a sign that healthcare employers' requests for exemptions are unlikely to take root.

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Cell and gene therapies could be a safer bet than other drugs

STAT

Want to stay on top of the science and politics driving biotech today?  Sign up  to get our biotech newsletter in your inbox. Good morning, everyone. Damian here with data on biotech’s belt-tightening, the advance of xenotransplantation, and the escalating Ozempic panic.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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Pharmacists Are Being Recognized for Their Contributions to the Field of Infectious Disease

Pharmacy Times

Jacinda Abdul-Mutakabbir, PharmD, MPH, AAHIVP, discusses being the second pharmacist in IDSA history to receive a society award and what this means not only for her, but for the field.

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AdventHealth picks Wellvana to transition its Florida primary care network to VBC for select patients

Fierce Healthcare

Wellvana, a value-based care enabler, is joining forces with AdventHealth as an exclusive partner to its primary care network in Florida. | AdventHealth is transitioning its entire primary care network in the state to value-based care for Medicare and Medicare Advantage patients. The partners’ goal is to improve clinical outcomes and lower the total cost of care.

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After repeat Humira biosimilar snubs, FDA turns down Teva and Alvotech's Stelara copycat

Fierce Pharma

Even as Teva Pharmaceuticals’ Icelandic counterpart Alvotech works to get its Reykjavik manufacturing facility back up to snuff, lingering problems at the plant—which derailed approval of the partn | The FDA shot down Alvotech and Teva's biosimilar candidate to Johnson & Johnson's Stelara over “certain deficiencies” uncovered by the FDA during a reinspection of the company's factory in Iceland earlier this year.

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Listen: Merger Mondays, Ozempic panic, & CRISPR’d pigs

STAT

When is a billion-dollar deal a bad omen? Has Wall Street gone overboard on Ozempic? And how do you edit a chicken? We cover all that and more this week on “The Readout LOUD,” STAT’s biotech podcast. We discuss Bristol Myers Squibb’s multibillion-dollar acquisition of Mirati Therapeutics and what it means for a biotech sector still in a slump.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Pfizer, playing catch-up with Novartis, bags FDA approval for drug combo in lung cancer

Fierce Pharma

Pfizer is expanding the reach of its BRAF-MEK combo as the pharma giant looks to further build up its oncology presence. | Pfizer is expanding the reach of its BRAF-MEK combo as the pharma giant looks to further build up its oncology presence.

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Three Myths Sabotaging Healthcare Innvoation

Fierce Healthcare

By Theo Koury, MD, President, Vituity | Health systems are rethinking how they engage with patients and physician ownership is paving the way. Read on to break into innovation.

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After Novo's Ozempic logs victory in kidney disease trial, dialysis heavyweight DaVita raises doubts

Fierce Pharma

An apparent win for Novo Nordisk’s GLP-1 blockbuster Ozempic in chronic kidney disease (CKD) could herald a shift in how the condition has been treated for decades. | Based on the inclusion criteria for Novo Nordisk’s chronic kidney disease trial, dialysis bigwig DaVita believes there may only be “limited application” of the study’s findings to the overall CKD population.

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Expert Discusses the Value of Pharmacists in Telemedicine

Pharmacy Times

Cassie Brunelle, PharmD and Pharmacist-in-Charge at Nurx discusses the role of the pharmacist, how the pharmacy profession has changed, and what is to come in the field.

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After FDA snub, Lilly's mirikizumab looks to regain momentum with phase 3 Crohn's win

Fierce Pharma

After the FDA passed on an approval for mirikizumab in ulcerative colitis earlier this year because of manufacturing shortfalls, the Eli Lilly drug is gaining new momentum with a win in a phase 3 C | A majority of Crohn's disease patients experienced a clinical response and clinical remission after treatment with mirikizumab, the company said. The results provide a boost after mirikizumab's surprise manufacturing-related FDA rejection in April.

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Bacille Calmette–Guérin Vaccine May Prevent Most Common Cause of Death in Patients With HIV

Pharmacy Times

Investigators suggest that the Bacille Calmette–Guérin vaccine, which prevented tuberculosis in nonhuman primates infected with SIV, can also protect against HIV.

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Telehealth Model, CGM Use Supports T1D, T2D Self-Management

Drug Topics

There has been growing evidence around the potential for the success of remote diabetes care and CGM technology use.

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Expert: Mentorship in Oncology Pharmacy Has an Impact

Pharmacy Times

The president of HOPA discusses the importance of mentorship in oncology pharmacy as well as the value of HOPA’s mentorship initiatives.

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STAT+: Better Therapeutics data on apps’ benefit with GLP-1s, Orexo hits a snag

STAT

You’re reading the web edition of STAT’s Health Tech newsletter, our guide to how technology is transforming the life sciences. Sign up to get it  delivered in your inbox every Tuesday and Thursday.  Diabetes: Better shows data on app’s benefit with GLP-1s Better Therapeutics  announced  top-line data suggesting that its prescription app for diabetes treatment, AspyreRx, can boost the impact of GLP-1 diabetes treatments.

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Fierce Pharma Asia—GSK, Zhifei's vaccine pact; BioNTech's latest China deal; Biocon's biosimilar rejection

Fierce Pharma

GSK has tapped Chongqing Zhifei to distribute Shingrix in China. BioNTech in-licensed a HER3 antibody-drug conjugate from Chinese company MediLink Therapeutics. | GSK has tapped Chongqing Zhifei to distribute Shingrix in China. BioNTech in-licensed a HER3 antibody-drug conjugate from Chinese company MediLink Therapeutics. The FDA rejected Biocon's proposed biosimilar version of Novo Nordisk's NovoLog—again.

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New FDA SaMD Guidance Will Bring Monumental Changes to Industry

PharmExec

A discussion of the impact the new FDA SaMD guidance, identifying the differences between companion apps and SaMD, and what to expect from this combination in the future.

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Food Allergy Is Another Looming Epidemic

Pharmacy Times

Contrary to earlier advice, new research suggests introducing infants to potential allergens early may reduce risk of developing allergies to those foods

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Dollar General, Bayer partner to increase access to fruit, veggies for kids

Drug Store News

School districts and organizations whose students will receive fresh produce coupons are in Florida, Louisiana, Maryland, Michigan, Mississippi, Missouri, Ohio and Pennsylvania.

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Technology Can Support, Enhance the Work of the Health Care Workforce

Pharmacy Times

Karline Peal, MBA of Vanderbilt Ingram Cancer Center discusses the positive impact technology has had in health care and how it can be implemented in the future.

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MHRA regulation overhaul: new scheme for lowest-risk UK clinical trials

European Pharmaceutical Review

A new scheme from the Medicines and Healthcare products Regulatory Agency (MHRA) is set to cut the approval time for the lowest-risk clinical trials in the UK by over half. The new Notification Scheme is based on that outlined in the MHRA’s clinical trials consultation, which was endorsed by 74 percent of those who responded. It forms a significant part of the regulator’s overhaul of the clinical trials regulation announced in March 2023, which aims to make the UK a prime location for con

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Follow-Up Survey Indicates Cancer Centers Continue to Experience Chemotherapy Shortages

Pharmacy Times

Larger institutions have continued to treat patients who needed carboplatin or cisplatin; however, the survey results don’t include smaller cancer centers that may face access challenges.

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STAT+: Pharmalittle: Life sciences deals on track to hit lowest point since 2017; EU regulators order Illumina to divest Grail

STAT

Good morning, everyone, and welcome to another busy day. We are scrambling, in fact, to update our to-do list, schedule online calls, and sort out deadlines. To cope, we are quaffing several cups of stimulation, of course. Our choice today is maple bourbon. Meanwhile, here is the latest selection of interesting items for you to peruse. We hope your day is successful and productive.

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Survey Results Highlight Value of Experience, Certifications for Pharmacist Salaries

Pharmacy Times

Although education and training have historically been considered the primary factors influencing pay, the survey results challenge this notion.

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GoodRx, Navitus Health Solutions launch Connect Program

Drug Store News

​​​​​​​Eligible Navitus members can now automatically access real-time comparative pricing at point of sale to improve affordability.

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Research predicts 2029 small molecule oncology market leaders

European Pharmaceutical Review

Strong demand for small molecules as treatment for non-small cell lung cancer (NSCLC) in the eight major markets means that the small molecule treatment market for the disease is expected to reach over $15 billion by 2029. This represents approximately 40 percent of the total NSCLC market, stated GlobalData. Sales for AstraZeneca’s Tagrisso are anticipated to exceed $7 billion and hold a 48 percent share of the market of small molecules in lung cancer treatment by 2029, according to data and ana

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