Tue.Oct 24, 2023

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Diabetes Health Burden Negatively Impacts Quality of Life in Elderly Patients

Drug Topics

A study published in Primary Care Diabetes pinpoints those at most risk and recommends education to improve the quality of life in diagnosed elderly patients.

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CDC Issues Alert to Address Shortage of RSV Treatment Nirsevimab

Pharmacy Times

Nirsevimab-alip (Beyfortus; Sanofi and AstraZeneca) is a monoclonal antibody approved to prevent against respiratory syncytial virus (RSV) lower respiratory tract disease in newborns and infants under 8 months of age born during or entering their first RSV season.

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Trending Sources

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STAT+: For Parkinson’s disease, advances spurred by Apple Watch offer a glimmer of hope

STAT

Since the Apple Watch was unveiled in 2014, it has been trumpeted not only as a high tech fashion accessory, but also as a way for people to track their own health and fitness. It has evolved as a popular cardio tool for such uses as heart rate monitoring, recording your ECG, and measuring the oxygen saturation of your blood. But now, after nearly a decade of development, the Apple Watch is being leveraged on an entirely new health frontier: Parkinson’s disease, the degenerative brain dis

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Independent Rx Forum - NCPA Conference: Legal Update on PBM Litigation

Pharmacy Times

Jack Mozloom, vice president of Public Affairs at the National Community Pharmacists Association (NCPA), speaks with Matt Seiler, general counsel at NCPA, about the current PBM litigation at the 2023 NCPA Convention.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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AstraZeneca, maker of FluMist, seeks to allow at-home administration of vaccine

STAT

People eligible to use the only needle-free flu vaccine available in the United States may be able, next year, to give it to themselves or to eligible children at home. AstraZeneca, which makes the vaccine FluMist, announced Tuesday it has submitted to the Food and Drug Administration a supplemental biologics license application that would allow for self-administration of the vaccine by people ages 18 through 49, and would allow people 18 and older to give the vaccine to eligible children.

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Amgen plans to lay off 350 former Horizon employees after $28B buyout

Fierce Pharma

In the biopharma industry, post-merger layoffs are often a question of when and how many. | In the biopharma industry, post-merger layoffs are often a question of when and how many. In the case of Amgen’s $27.8 billion buyout of Horizon, they came quickly. Around 350 former Horizon employees are being told this week that their positions will be eliminated.

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Study Links Long COVID With Short Sleep Duration

Pharmacy Times

Risk of long COVID was 3 times higher in those who had pre-existing conditions and a short sleep duration, compared to those with no pre-existing conditions and adequate sleep.

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The official definition of infertility now includes LGBTQ+ and single people

STAT

Infertility has a new definition in the U.S. — one that could make a big difference to would-be parents who are single or LGBTQ+. Last week, the American Society for Reproductive Medicine (ASRM) issued an expanded description of the condition, stating that infertility involves “the need for medical intervention, including, but not limited to, the use of donor gametes or donor embryos in order to achieve a successful pregnancy either as an individual or with a partner.

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Nivolumab Combination Regimen Improved Survival of Patients with Bladder Cancer By A Third Compared to Chemotherapy Alone

Pharmacy Times

The novel combination met the co-primary endpoints of progression-free survival and overall survival during the CheckMate -901 trial, also demonstrating sizeable improvement in objective response.

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Opinion: Do dementia villages actually work? We just don’t know

STAT

Recently, dementia villages have gained popularity in Europe and Australia as an all-in-one solution to caring for and improving the lives of those with Alzheimer’s disease and dementia. The New York Times has reported that it looks like the “future of home care.” Dementia villages are small-scale communities that offer shared housing, minor medical care, and psychosocial support in a neighborhood setting.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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Pfizer’s RSV Vaccine Can Help Protect Older Adults From Severe Disease

Drug Topics

Stephen L. Foster, PharmD, FAPhA, FNAP, discussed the new vaccine and RSV prevalence at the National Community Pharmacists Association 2023 Convention and Expo.

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STAT+: With an old approach but new energy, ADCs take center stage as promising cancer treatments

STAT

MADRID — If you had to pinpoint one subject that stood out at this year’s European Society for Medical Oncology meeting , a massive conference with thousands of people from 140-some countries and 2,500 studies presented, it would be a burgeoning type of cancer treatment called antibody-drug conjugates. The conference opened to the news that Merck had signed one of the biggest licensing deals in industry history — worth up to $22 billion — to partner on three of the co

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Labor shortages, claims denials, supply chain still hamstring hospital margins, survey shows

Fierce Healthcare

Healthcare’s days of widespread contract labor reliance may be over, but hospitals and health systems are still frequently reporting labor shortages and other operating hurdles keeping them from he | Contract labor reliance may be largely in the past, but hospital leaders say there's still plenty of hurdles ensuring “a slow climb" to long-term operational sustainability.

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Opinion: Insulin is increasingly affordable in the U.S. What about the rest of the world?

STAT

In March, Eli Lilly, Novo Nordisk, and Sanofi — the world’s three largest insulin manufacturers — committed to reducing the U.S. list price of insulin, a drug that millions of people require to live. Following two decades of sharp increases for consumers, the companies vowed to cut insulin prices for some insulins by at least 70%, meaning many people could see their insulin costs capped at $35 a month in the near future.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Expert: Pharmacists Are Stepping Out of the Pharmacy to Educate First Responders, Parents, Teachers, Children on Drug Safety

Pharmacy Times

Taking pharmacists out of the dispensing setting and placing them in communities as educators on drug safety is reaping rewards.

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STAT+: ‘Missed opportunities’: Why a U.K. government plan to disclose financial ties between pharma and docs may fall short

STAT

Earlier this month, the U.K. government issued a proposal to gather information and opinions about payments that drug and device makers give to the medical community. The move came amid ongoing concern over financial ties between companies and health care professionals, an issue that has largely been left to trade groups to police. In an effort to take greater control, the government plans to create what resembles the OpenPayments database in the U.S., which emerged from scandals and probes into

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Teladoc brings in $660M in Q3 revenue, reaches 90M members as executives focus on boosting bottom line

Fierce Healthcare

Teladoc's third-quarter revenue grew 8% to reach $660 million, boosted by solid performance in its chronic condition management business and steady membership growth as the company now touts 90 mil | Teladoc's scale, strong financial position and free cash flow performance put the company in a competitive position compared to many virtual care startups struggling in the current macroeconomic environment, executives said.

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ESMO: Merck, in flurry of studies, shows Keytruda's power and limitations

Fierce Pharma

At this year’s congress of the European Society for Medical Oncology (ESMO), Merck & Co. unleashed a flurry of studies showing Keytruda’s power across multiple tumor types. | Across four separate studies, Merck’s PD-1 juggernaut Keytruda—in combination with other cancer meds—charted complete and partial wins in cervical cancer, early breast cancer and stomach cancer.

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STAT+: A controversial new study examines traditional Chinese medicine’s potential cardiac benefits

STAT

A traditional Chinese medicine compound used for cardiac benefits might help reduce the incidence of major adverse cardiac and cerebrovascular events and even cardiac death rates, according to a new study published Tuesday in the Journal of the American Medical Association. However, some outside experts expressed skepticism about the result. Tongxinluo — which means “to open (tong) the network (luo) of the heart (xin)” in Mandarin —  is a traditional Chinese medi

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Direct Contracting model reaches nearly $500M in net savings

Fierce Healthcare

The Center for Medicare and Medicaid Innovation (CMMI) unveiled 2022 calendar year results for the Direct Contracting Model on Monday. | More than three-quarters of those who participated in the program reaped savings, data from CMMI revealed.

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STAT+: Startup launches with $245 million for twice yearly asthma treatment

STAT

A new biotech has raised $245 million to test a new asthma medication that could compete with one sold by Amgen and AstraZeneca. The startup, Aiolos Therapeutics, was founded by former Genentech colleagues Khurem Farooq and Tony Adamis after they stumbled upon a drug being developed by Chinese pharma company Jiangsu Hengrui Pharmaceuticals Co., Ltd.

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AstraZeneca's self-administered nasal flu vaccine gets one step closer to FDA approval

Fierce Pharma

On the market for two decades, AstraZeneca’s nasal spray flu vaccine, FluMist, may become available for self-administration as soon as next year. | On the market for two decades, AstraZeneca’s nasal spray flu vaccine, FluMist, may become available for self-administration as soon as next year. The FDA has accepted AZ’s supplemental biologics license application (sBLA) for self-administered FluMist Qudrivalent.

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Independent pharmacies sue Express Scripts, allege price-fixing

Fierce Healthcare

Several independent pharmacies have filed suit against pharmacy benefit management giant Express Scripts, alleging that the company colluded with Prime Therapeutics to fix reimbursement rates. | Several independent pharmacies have filed suit against pharmacy benefit management giant Express Scripts, alleging that the company colluded with Prime Therapeutics to fix reimbursement rates.

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Novartis delays Pluvicto filing as CEO spots industry 'conundrum' with FDA

Fierce Pharma

Novartis entered a new era after spinning off Sandoz earlier in October. | Novartis entered a new era after spinning off Sandoz earlier in October. As the pure-play innovative medicines company reports strong growth from the business it’s now built on, one product faces a delay.

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12 ways to get rid of phlegm

The Checkup by Singlecare

“Phlegm can be defined as a type of mucus produced by your lungs and respiratory tract—often during a common cold or other respiratory infection, “ says Kelvin Fernandez, MD , an internal medicine physician in New Jersey and Medical Residency Advisory at ACE Medical Boards. Mucus is a thin, slippery substance that is considered healthy. When the amount of mucus is more than normal, it can be associated with nasal symptoms of a runny nose or post-nasal drip.

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Europe’s pharmaceutical packaging market to value over $35bn by 2028

European Pharmaceutical Review

Europe’s pharmaceutical packaging and labelling market is projected to reach $35.78 billion in 2028, according to a report by Arizton. Having been valued at $27.04 billion in 2022, the pharmaceutical packaging and labelling market in Europe is expected to expand at a compound annual growth rate (CAGR) of 4.78 percent up to 2028. Europe’s position in the global pharmaceutical packaging and labelling market The authors highlighted that Europe led the worldwide market at 27 percent in 2022.

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HCA Healthcare's newly consolidated physician staffing venture is bleeding $50M per quarter, execs tell investors

Fierce Healthcare

Editor's note: Updated at 12:15 p.m. Oct. 24 with commentary from HCA Healthcare's Q3 earnings call. | The for-profit system celebrated "continued solid demand for our services" during its Q3 2023 earnings call, but had to defend its decisions surrounding Valesco Physician Services to analysts and investors.

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After $5.8B deal, Bristol Myers' years-long courtship of Mirati revealed in securities filing

Fierce Pharma

Mirati Therapeutics was long rumored to be the target of a Big Pharma buyout before Bristol Myers Squibb put up $5.8 billion for the California-based cancer drug developer in early October. | Mirati Therapeutics was long rumored to be the target of a Big Pharma buyout before Bristol Myers Squibb put up $5.8 billion for the California-based cancer drug developer in early October.

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Why AstraZeneca’s CEO is accusing British tabloids of ‘fake news’

STAT

Want to stay on top of the science and politics driving biotech today?  Sign up  to get our biotech newsletter in your inbox. Good morning, everyone. Damian here with news of a 2021-sized biotech round that has echoes of 2011, plus an ESMO recap and a curious stock move.

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ADDF announces speech database to identify biomarkers for Alzheimer’s

Pharmaceutical Technology

SpeechDx will contain recorded voice samples and other data, which will be used to develop algorithms for creating new speech biomarkers.

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Phase 3 Trial Begins for Combination Influenza and COVID-19 Vaccine

Pharmacy Times

mRNA-1083 is an investigational combination vaccine designed to prevent influenza and COVID-19.

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Scoping Review Reveals Effects of COVID-19 on Peri- and Post-Menopausal Women

Drug Topics

A review published in General Hospital Psychiatry shows large, negative impacts on menopausal women.

Hospitals 112
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STAT+: Pharmalittle: Pharma moves closer to a pricing deal with U.K.; FDA to review AstraZeneca request for self-administered flu vax

STAT

Rise and shine, everyone, another busy day is on the way. We can tell because the official mascots are racing madly about the Pharmalot grounds and the parade of vehicles is picking up nearby. As for us, we are dutifully firing up the coffee kettle to brew another cup of needed stimulation. Our choice today is the oh-so tasty maple bourbon. Please feel free to join us.

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Dara Reneé named Pantene’s latest Healthy Hair Ambassador

Drug Store News

Actress Dara Reneé is partnering with the brand to share how she cares for her signature curls while encouraging others to share their own #PanteneHair journey.

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