Thu.Oct 19, 2023

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Veterinarians and Pharmacists Discuss Challenges Around Pet Medications

Drug Topics

Veterinarians and veterinarian pharmacists weigh in on issues around working with pet medications.

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Expert: Celebrating Pharmacists’ Role in Health Care, How the Profession Has Changed

Pharmacy Times

The assistant program director at Mayo Clinic discusses the significance of pharmacists’ role in health care, changes throughout the industry, and her passion for mentoring pharmaceutical students.

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When Vets Send Patients to Independent Pharmacies, Everyone Can Benefit

Drug Topics

When pet parents fill a prescription online, they lose the opportunity to consult with a pharmacist.

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Study Results Indicate Precision Therapies Make Up Approximately Half of FDA-Approved Oncology Drugs

Pharmacy Times

This finding underlines the need for methods that address multiple genomic alterations and targeted therapies effective in tumors driven by variations in suppressor genes or transcription factors.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Lawmakers mull lifting ban on physician-owned hospitals as doc lobbying groups claim major cost savings

Fierce Healthcare

A new analysis backed by doctor lobbying groups suggest that physician-owned hospitals could have fueled about $1.1 billion in savings across 20 of Medicare’s most expensive conditions in 2019— tho | Lobbying groups in favor of overturning the ban on new physician-owned hospitals outlined broad cost savings if 2019's Medicare patients were treated at such facilities instead of a traditional hospital.

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Pharmacists Play Important Role in Behavioral Health Care, Preventing Over- or Under-Prescribing

Pharmacy Times

There are 3 main medication-related issues for mental health care, which includes polypharmacy, nonadherence to prescribed medication, and underutilization of medications.

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Expert: Improving Efficiency of Biosimilar Operations, Advancing Interchangeable Biosimilar Development Among Top Priorities for FDA

Pharmacy Times

The biosimilar landscape is growing, but the FDA should leverage analytical data to efficiently determine the quality of these products and propel them toward approval, according to a session at the Academy of Managed Care Pharmacy’s Nexus 2023 conference.

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Centerstone taps tech company Lyssn to build out AI-based training for behavioral health clinicians

Fierce Healthcare

There is a lot of buzz about the use of artificial intelligence to help with clinical documentation and administrative tasks. | Centerstone, a large nonprofit mental health system, is working with tech company Lyssn to leverage its AI-powered platform to train its team of more than 3,000 clinicians in the latest evidence-based practices. The partnership also includes developing new solutions and long-term revenue sharing.

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RBX2660 Leads to Recurrent-Free Outcomes for Patients With Clostridioides difficile Infection

Pharmacy Times

Among individuals who received systemic antibiotics within 8 weeks, 6 months, 12 months, and 24 months of receiving fecal microbiota, RBX2660 prevented recurrence.

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STAT+: Zuckerberg and Chan on track to put $50 billion toward science: ‘That’s the trajectory we’re on’

STAT

Mark Zuckerberg and Priscilla Chan sit atop a fortune that is currently valued at $113 billion, and they’ve promised to give almost all of it away. Their philanthropic funding group, the Chan Zuckerberg Initiative, is committed to investing in an array of fields, including science, education, housing insecurity, and expanding access to startup capital to entrepreneurs of color.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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Actor and epilepsy advocate Greg Grunberg wants the world to ‘talk about it’

PharmaVoice

The actor of “Heroes” and “Star Wars: The Force Awakens” fame is starring in another role as a patient advocate for people with epilepsy.

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Michael J. Fox on how far Parkinson’s research has come: ‘We don’t want to be celebrated. We want to get things done.’

STAT

When Michael J. Fox was diagnosed with Parkinson’s disease at age 29, his clearest symptom was a small one — his pinky finger was twitching. But even by that stage, 70% to 80% of a patient’s dopamine-producing cells are already gone, Fox said. “What happens in that time, that shadowy place?” Fox said, referring to the period before his pinky finger first started twitching.

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Interchangeability Designation Still Widely Debated, Prescribers Hesitant About Biosimilars

Pharmacy Times

The FDA is the only authority that can designate a biosimilar as interchangeable with its reference product, which requires that the product has similar clinical results for the same indication.

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Older adults are vulnerable in a warming climate. Better buildings could help protect them

STAT

In 2003, during Europe’s worst heat wave in centuries, almost 15,000 people died in France. About three-quarters of those deaths occurred indoors , and approximately 80% of the people who died were over 75 , an age at which people tend to be less capable of perceiving heat and less well-equipped to adapt to it. In the coming years of mounting climate change, people around the world — particularly older adults — are expected to be similarly vulnerable.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Mayo Clinic, LifePoint Health sue pharmas over 'pay for delay' deals keeping blood cancer drug prices high

Fierce Healthcare

The Mayo Clinic and LifePoint Health believe that collusion within pharmaceutical industry forced their organizations to overpay for the multiple myeloma drug Revlimid, and are petitioning the cour | The health systems said agreements between Revlimid's owners, Celgene and Bristol-Myers Squibb, and other drugmakers that delayed full production of generic alternatives are anticompetitive and have forced their organizations to overpay.

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Counsel Patients, Parents on the HPV Vaccine

Pharmacy Times

Understanding the recommended ages for vaccination is crucial to properly advise patients and parents who have questions

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GoodRx, Sanofi to offer insulin for $35, regardless of insurance, at select pharmacies

Fierce Healthcare

GoodRx is teaming up with Sanofi to offer consumers access to its most prescribed insulin, Lantus, for $35 at thousands of pharmacies nationwide. | All Americans with a valid prescription, regardless of their insurance status, can use GoodRx at more than 70,000 retail pharmacies to access a 30-day supply of Lantus for $35.

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Experts Highlight Need for Increased Screening for Dementia, Alzheimer Disease

Pharmacy Times

Approximately 96% physicians feel it is important to assess patients aged 60 years and older for cognitive impairment, but 48% of these patients have no had assessments from their physician.

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STAT+: The future of Biogen: Pragmatism, ‘a few moonshots,’ and no Twinkies

STAT

Two years after a big scientific swing nearly pushed Biogen to the brink, CEO Christopher Viehbacher is embarking on a corporate rethink, one that balances Biogen’s characteristic risky bets with a frank commitment to pragmatism. Speaking at the STAT Summit in Boston on Thursday, Viehbacher said his Biogen predecessors fell off track through a few unsound investments and an all-or-nothing bet on Aduhelm, the Alzheimer’s disease treatment that became a pharmaceutical cautionary tale

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ESMO: In PD-1 battle GSK waged on Merck, Jemperli appears to show survival edge over Keytruda in lung cancer

Fierce Pharma

Last year, a first-of-its-kind head-to-head clinical trial between two PD-1 inhibitors went in GSK’s favor. Now, the British pharma has some new patient survival data to celebrate. | Last year, a first-of-its-kind head-to-head clinical trial between two PD-1 inhibitors went in GSK’s favor. Now, the British pharma has some new patient survival data to celebrate.

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STAT+: Merck, Daiichi Sankyo to partner on targeted chemotherapy drugs in deal worth up to $22 billion

STAT

MADRID — Merck is paying billions of dollars to partner with Daiichi Sankyo on a series of cancer drugs, underscoring the excitement around targeted chemotherapy treatments.   The deal includes a $4 billion upfront payment and an additional $1.5 billion over the next two years. Up to $16.5 billion more is on the table depending on the success of the drugs in development.

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Takeda’s stem cell treatment Alofisel flunks phase 3 trial in Crohn's complication

Fierce Pharma

After trimming an early-stage Crohn’s disease candidate from i | After trimming an early-stage Crohn’s disease candidate from its pipeline this year, Takeda is dealing with the failure of another of its therapies in a related indication. Alofisel (daradstrocel), a stem cell therapy designed to treat one of the most debilitating complications of Crohn’s—complex perianal fistulas (CPF)—has come up short in a phase 3 trial.

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STAT+: GSK CEO on pharma giant’s new direction: ‘We’re in the business of preventing and treating disease’

STAT

The story of GSK is one of reinvention, CEO Emma Walmsley said at the STAT Summit in Boston on Thursday. Having shed its consumer division, the British drug giant is writing a new chapter as a pure-play biopharma company dedicated to the prevention, as well as treatment, of disease. GSK’s recent launch of a new RSV vaccine for adults is emblematic of this move, adding to a portfolio that includes other vaccines, such as the very successful Shingrix for shingles, as well as drugs for HIV,

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EU, UK authorities crack down on fake versions of Novo Nordisk's Ozempic

Fierce Pharma

As Novo Nordisk works to get a handle on sales of illicit semaglutide, British and European drug authorities are warning that they've discovered falsified Ozempic pens on their home turf. | Novo Nordisk's hugely popular diabetes and weight-loss meds have attracted their share of counterfeits. Now, British and European drug authorities are warning that they've discovered falsified Ozempic pens on their home turf.

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STAT+: A 50-year battle over one additive highlights FDA’s challenges with food safety

STAT

WASHINGTON — Richard Nixon was the president when the Food and Drug Administration issued its first warnings about brominated vegetable oil, based on reports it could harm a slew of vital organs, from the liver to the heart. But the agency still hasn’t actually banned the ingredient — it only sent a proposed ban to the White House in August.

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Pharmacists’ Involvement with Gene Therapies, Potential Candidates, Forecasting Effectively

Pharmacy Times

In this field, Marshall notes that pharmacists can help by building forecasts and assist with managing members’ care before and after gene therapy.

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Listen: Live from the 2023 STAT Summit

STAT

What if CRISPR isn’t all that commercial? How does the NurOwn story end? And how do you pronounce “Bayer”? We cover all that and more this week on “The Readout LOUD,” STAT’s biotech podcast. Live from Boston at the 2023 STAT Summit, we discuss the latest news in the life sciences, including a milestone in genome editing, a twist in the search for ALS treatments, and the polarizing process of saying words in biotech.

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More Biosimilars Are Entering the Pharmacy Side of The Market

Pharmacy Times

Biosimilars in the pharmacy benefit are as effective as their reference drug, but it’s important for the pharmacist to clarify this to patients.

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STAT+: Beam Therapeutics to lay off 20% of its staff, reevaluate programs as it cuts costs

STAT

Beam Therapeutics said Thursday morning it would lay off 20% of its staff — or around 100 employees — and pause or reevaluate certain programs as it looks to cut costs. It’s a notable setback for a gene-editing company that quickly raised over $1 billion in the few years after its co-founder, David Liu, described a new form of CRISPR, called base editing, that allowed researchers to change individual letters of DNA.

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PTC inks Royalty deal worth up to $1.5B on Genentech-partnered SMA drug Evrydsi

Fierce Pharma

Amid a cost-cutting drive and a looming commercial threat in Europe, PTC Ther | PTC will hold on to 19% of its royalty interest in the Genentech drug with the option to sell the rest down the line. The company licensed the med to Genentech in 2011.

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STAT+: House committee hearing kicks off potential doctor pay reforms in Medicare

STAT

WASHINGTON — The House Energy & Commerce health subcommittee kicked off its first hearing in four years on whether to reform the way Medicare pays doctors. But they didn’t discuss how to pay for those changes. Lawmakers brought up 23 different bills on the topic, many of which are drafts that haven’t been introduced. A few bills addressed expiring payment initiatives.

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BMS, Halozyme score with subcutaneous version of Opdivo

Fierce Pharma

Months after ditching an auto-injected version of Opdivo (nivolumab), Bristol Myers Squibb has found success with a more traditional way to administer its oncology blockbuster—with a syringe and vi | Months after ditching an auto-injected version of Opdivo, Bristol Myers Squibb has found success with a more traditional way to administer its oncology blockbuster—with a syringe and vial.

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Opinion: A better way for doctors and health plans to manage genetic tests

STAT

New technology has a history of overwhelming existing systems that try to manage it, and that’s proving to be the case with genetic testing and health care. It’s been only 20 years since the completion of the Human Genome Project opened the door for genetic testing and its promise for more lifesaving screenings and precise, personalized medicine.

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Mental Health Issues During Adolescence Could Lead to Future Unhealthy Behaviors

Pharmacy Times

Latinx teens suffering with mental health issues are at risk of developing cardiovascular conditions in their future.

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