Mon.Jan 22, 2024

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Bipartisan Lawmakers Signal Support for H.R. 1770

Drug Topics

The Equitable Community Access to Pharmacist Services Act seeks to ensure that seniors in rural and underserved communities have access to care and services from pharmacists for common infectious diseases.

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Pharmacists Are Transforming and Optimizing HIV Treatment

Pharmacy Times

Regardless of a pharmacist’s practice site or type, they play an integral role in ensuring the treatment success of patients with HIV.

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Trending Sources

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RSV Hospitalization Risk Higher than Flu, Omicron Among Children

Drug Topics

Of the 2596 patients included in the study, the hospitalization rates were 31.5% for Omicron, 27.7% for influenza, and 81.7% for RSV.

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Why many more people are lining up for a flu shot than a Covid vaccine

STAT

America is over the Covid vaccine. Frantic lineups for scarce doses when Covid vaccines first became available have long since given way to widespread indifference. Each new round of boosters has drawn fewer bared arms than the round before it. The Centers for Disease Control and Prevention estimates that, as of Jan. 6, a mere 21.5% of Americans aged 18 and older and 11% of children have been vaccinated with the latest Covid vaccine.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Obstetrical Patient Dies After Inadvertent Administration of Digoxin for Spinal Anesthesia

Pharmacy Times

The ampule of digoxin was accidentally taken from automated dispensing cabinet instead of bupivacaine

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Opinion: The FDA and FTC need to crack down on TikTok and Instagram influencers pitching prescription drugs

STAT

In June, the Food and Drug Administration issued a warning letter about advertisements for the drug Recorlev for Cushing’s syndrome — its first in more than a year about webpages that make “false or misleading claims” about prescription drugs. More recently, in December the agency published guidance about TV and radio advertisements.

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More Trending

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Dana-Farber expands studies to be retracted to 6, plus 31 to be corrected over mishandled data

STAT

A review of alleged data manipulation in studies involving four top scientists at Dana-Farber Cancer Institute has led to plans to retract six papers and correct 31 manuscripts, the institute confirmed on Monday. The news comes as the famed cancer research and treatment center is now reviewing scores of studies co-authored by some of its leading researchers, including CEO Laurie Glimcher, COO William Hahn, and prominent scientists Irene Ghobrial and Kenneth Anderson.

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Gilead's Trodelvy fails to extend survival in lung cancer study, prompting selloff

Fierce Pharma

Even as Gilead looks to become an oncology powerhouse in the coming years, the company on Monday recorded a major setback for its antibody-drug conjugate (ADC) Trodelvy. | The antibody-drug conjugate did not significantly improve survival outcomes compared with a chemotherapy alone in previously treated patients with metastatic non-small cell lung cancer.

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STAT+: In ‘march-in’ rights, some see a tool to lower drug prices. Others see a threat to intellectual property

STAT

In the fall of 2020, Robert Sachs was prescribed a medication to treat prostate cancer that had metastasized into some of his bones. He welcomed the treatment, but was surprised by the $740 monthly copay cost, even after coverage from Medicare and supplemental insurance. So Sachs began reading about the drug, Xtandi , and found the annual list price at the time was about $156,000, or $427 a day, for men with commercial health insurance.

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Report: Oncology, Immunology Projected to Lead Global Spending From 2024 to 2028

Pharmacy Times

The IQVIA Global Use of Medicines report for 2024 predicts that loss of brand exclusivity will negatively impact global market growth.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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STAT+: Gilead’s Trodelvy fails in lung cancer and raises new questions on antibody drug conjugate drugs

STAT

Gilead Sciences said Monday that Trodelvy, its “smart-bomb” medicine that combines an antibody with chemotherapy, did not significantly extend the lives of patients with metastatic non-small cell lung cancer when given after a first treatment failed. The result, from a closely watched study called Evoke-01, will be seen as a disappointment by investors and oncologists alike.

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Eli Lilly's troubled NJ manufacturing site in hot water again over maintenance, quality control lapses

Fierce Pharma

Eli Lilly’s beleaguered manufacturing site in Branchburg, New Jersey, is back in the U.S. Food and Drug Administration’s crosshairs, Reuters first reported. | Following a July inspection, the FDA has uncovered eight new production deficiencies at Eli Lilly's Branchburg production plant. The observations run the gamut from problems in tracking manufacturing processes and quality controls to equipment calibration lapses and poor facility maintenance.

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STAT+: A Harvard course seeks to put food on the table in medical education

STAT

BOSTON — Doctors often don’t have a lot of time to chat with patients during medical appointments — which means that conversations about nutrition can wind up taking a backseat to other concerns. But during a recent weeklong course at Harvard T.H. Chan School of Public Health, preventive cardiologist Stephen Devries enlisted two dozen students in the mission to integrate nutrition into clinical medicine — changing the way medicine is taught and health care is delivere

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'Podnosis': What’s next for health tech investing in 2024?

Fierce Healthcare

The digital health and health tech sectors had a tough year in the wake of the COVID-19 pandemic, navigating through a turbulent hype cycle. | This week on "Podnosis," Sofia Guerra and Steve Kraus from Bessemer Venture Partners sat down with Fierce Healthcare's Heather Landi to discuss the health tech sector's performance, unraveling the factors that contributed to its current state.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Medicare Advantage update pushes Wall Street to reset expectations

STAT

You’re reading the web version of Health Care Inc.,  STAT’s weekly newsletter  following the flow of money in medicine.  Sign up  to get it in your inbox every Monday.  Summa wrestling for physician buy-in General Catalyst finally has the hospital system it wants. But there’s some skepticism that the venture capital firm will live up to its promises and get the required buy-in from physicians and other medical staff, my colleague Tara Bannow reports.

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How Will Patients Benefit From Medicare Drug Price Negotiations?

Drug Topics

The Congressional Budget Office last year estimated that price negotiation will lower average drug prices in Medicare and will reduce the budget deficit by $25 billion in 2031, including lowering Part D spending by $14 billion and Part B spending by $9 billion. Other federal spending will be lowered by $1 billion.

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STAT+: FDA sets aggressive deadline for inspection overhaul

STAT

WASHINGTON — Food and Drug Administration officials hope to finish this year a massive overhaul of the way the agency inspects facilities that make drugs, medical devices, and food products, they said Friday. The reorganization was spurred by the FDA’s mishandling of the infant formula crisis. The agency was slow to inspect a major infant formula plant despite a whistleblower complaint about deadly bacterial contamination at the facility.

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Berberine May Reduce Inflammation of Lung Tissues in Patients With Metastatic Colorectal Cancer

Pharmacy Times

Berberine was associated with a reduction in inflammatory markers in the lungs, which was caused by the colorectal cancer.

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New tool for tracing blood cells’ ancestry might one day help predict disease risk

STAT

The human blood system is in a constant state of turnover. First-line immune defenders, like neutrophils, need to be replaced after just four to eight hours, platelets can last a week, red blood cells up to four months, and some white blood cells, like memory B cells, live for decades. The heroic task of constantly replenishing these ranks, and making sure the balance of different types of blood cells is right, falls to a primitive reserve of stem cells that reside deep in the bone marrow.

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Pharma waste management: Balancing cost, compliance, and environmental responsibility

pharmaphorum

Pharma waste management is crucial for balancing cost, compliance, and environmental responsibility in the healthcare industry. Explore strategies and best practices for effectively managing pharmaceutical waste, while ensuring regulatory compliance and minimising environmental impact.

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Opinion: STAT+: Some countries are moving to digital prescription drug information for patients. The U.S. shouldn’t follow suit

STAT

Getting a new prescription can be overwhelming: medication schedules, foods to eat or avoid, interactions between different drugs. Having all of these details in accessible, printed documents keeps patients informed and mitigates the risk of medication errors. However, there’s a growing movement across the world to eliminate printed medication information, making it harder for patients to learn about the drugs that, in many cases, save their lives.

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Is drinking bad for your cholesterol?

The Checkup by Singlecare

Cholesterol gets a bad rap, but the truth is that your body needs cholesterol. The health issue that arises for many people is when levels get out of whack—meaning, your “bad” cholesterol is too high while the “good” kind is too low. Lots of factors can affect cholesterol levels, including drinking alcohol. But if you’re keeping an eye on your cholesterol levels, does this mean you can never have a drink?

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Sandoz makes its first post-spinout acquisition

pharmaphorum

Sandoz makes its first acquisition since spinning out of Novartis, buying a Lucentis biosimilar from Coherus that will boost its position in the US market.

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Biden administration reinforces reproductive health obligations for payers, providers

Fierce Healthcare

The Biden administration’s healthcare regulators released new guidances, informational resources and other actions that reinforce payers and hospitals’ federal obligations surrounding reproductive | New letters and instructional materials out of HHS come amid reported contraception coverage barriers and escalating legal challenges over emergency abortion procedures.

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J&J's Balversa gets mixed approval in bladder cancer as FDA ratchets up scrutiny on subgroup data, patient survival

Fierce Pharma

When the FDA converts an accelerated approval into a full nod, it’s typically associated with a wider label for the drug at hand. | When the FDA converts an accelerated approval into a full nod, it's typically associated with a wider label for the drug at hand. But in the case of Johnson & Johnson’s Balversa, the FDA narrowed the use of the first-in-class bladder cancer drug in two ways and expanded it in another.

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Watch DSN: CVS Health's Sri Narasimhan discusses raising the bar for retail pharmacy expectations

Drug Store News

Sri Narasimhan, VP and head of enterprise customer experience at CVS Health, discusses using a customer-centric approach to cultivate higher retail pharmacy expectations among the public.

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Trial data raises questions about Imfinzi in liver cancer

pharmaphorum

AstraZeneca’s Imfinzi plus bevacizumab and TACE improved PFS compared to TACE alone in hepatocellular carcinoma patients in EMERALD-1, but more data may be needed before approval

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STAT+: Pharmalittle: We’re reading about Lilly plant problems, FDA reorganization plans, and more

STAT

Good morning, everyone, and welcome to another working week. We hope the weekend respite was relaxing and invigorating, because now the time has come to dive back in to the usual routine of online meetings, calls, and deadlines. But what can you do? The world, such as it is, continues to spin. So time to give it a nudge in a better direction with a cup or three of stimulation.

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Next stage in GSK’s Zantac defense gets underway today

pharmaphorum

A hearing will get underway in Delaware later today in the latest phase of GSK’s attempts to defend itself from allegations that its Zantac drug caused cancer in patients.

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ANCC vs. AACN: Which AGACNP Exam Should I Take?

Board Vitals - Pharmacist

The American Nurses Credentialing Center (ANCC) and the American Association of Critical Care Nurses (AACN) are the regulatory bodies responsible for conducting exams for individuals aspiring to obtain certification as a nurse practitioner. Both ANCC and AACN certifications serve as proof of the expertise possessed by nurse practitioners. An Adult Gerontology Acute Care Nurse Practitioner (AGACNP) cares for adult patients experiencing acute illness related to a condition.

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Three-Dose Hybrid Immunity Provided Older Adolescents With Robust Protection Against SARS-CoV-2 Infection

Pharmacy Times

Infection-induced immunity with 2-dose vaccination still offered protection against the circulating variant.

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Roche ducks out of AC Immune Alzheimer antibody alliance

pharmaphorum

End of the line for Roche’s 18-year alliance with Swiss biotech AC Immune, as it returns rights to Alzheimer's antibodies crenezumab and semorinemab

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ACIP Releases Updates On Vaccine Recommendations, 2024 Adult Immunization Schedule

Pharmacy Times

The schedule includes RSV vaccination, along with updated versions of the COVID-19 vaccine.

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This startup is building a new model for primary and specialty care in Austin, Texas. It just secured $95.5M to fuel its growth

Fierce Healthcare

This startup is building a new model for primary and specialty care in Austin, Texas. It just secured $95.

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