Mon.Oct 23, 2023

article thumbnail

Ribociclib With Endocrine Therapy Improved Invasive Disease-Free Survival in Patients With Early Breast Cancer

Pharmacy Times

Compared to endocrine therapy alone, the combination of ribociclib and endocrine therapy lowered the risk of cancer recurrence in patients with early breast cancer by 25.2%.

149
149
article thumbnail

Maternal Covid-19 vaccination offers infants immunity for up to 6 months

STAT

The risks of severe neonatal morbidity, neonatal death, and admission to the neonatal intensive care unit were all significantly lower during the first month of birth in infants whose mothers were vaccinated against Covid-19, and protection against the virus continued for up to six months after birth, according to a new study published Monday in JAMA Pediatrics.

Vaccines 145
Insiders

Sign Up for our Newsletter

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Trending Sources

article thumbnail

FDA Approves Biosimilar Infliximab-dyyb for Inflammatory Bowel Disease

Pharmacy Times

Infliximab-dyyb (Zymfentra; Celltrion USA) is a subcutaneous version of Celltrion’s infliximab biosimilar for the maintenance treatment of adults with moderately to severely active ulcerative colitis and Crohn disease.

FDA 144
article thumbnail

What will it take to end the crisis of Black deaths in the U.S.?

STAT

In the last two decades, Black Americans have suffered 1.63 million excess deaths compared to white Americans. Experts gathered at the STAT Summit in Boston last week to discuss the crisis of Black deaths in the U.S. and interventions that can help advance health equity. “If we continue to have a maternal health crisis, if we continue to have an infant mortality crisis … then we’re going to potentially see a situation or circumstance where Black people can be extinct in the

145
145
article thumbnail

Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

article thumbnail

Celebrating Pharmacists: "Pharmacists Month is Every Month for Me"

Pharmacy Times

Mike Schuh, PharmD, MBA, FAPhA, FFSHP, a medication management pharmacist at the Mayo Clinic in Florida, discusses his journey into the pharmacy profession and the evolution of pharmacists from product-oriented to clinical professionals.

article thumbnail

Fixing America’s health insurance woes is ‘actually very simple,’ says leading economist

STAT

Fixing the U.S. health care system can seem like a herculean task. But the solution is “actually very simple,” according to Massachusetts Institute of Technology economist Amy Finkelstein. In their recent book “ We’ve Got You Covered: Rebooting American Health Care ,” Finkelstein and Stanford economist Liran Einav describe how years of research have led them to the conclusion that the best way forward is for the U.S. to offer universal basic health care coverag

Insurance 145

More Trending

article thumbnail

STAT+: UnitedHealth discontinues a controversial brand amid scrutiny of algorithmic care denials

STAT

UnitedHealth Group and Optum are getting rid of the name of their tech-driven care management company just months after the company faced congressional criticism over the use of its algorithms to cut off payments for patients’ care. Discontinuing the NaviHealth name is part of a broader rebranding of Optum’s division that provides services to people at home and in post-acute facilities.

article thumbnail

American Heart Association Publishes Presidential Advisory Defining the Overlaps of Cardiovascular Disease, Kidney Disease

Pharmacy Times

This marks the first time that experts have defined cardiovascular-kidney-metabolic syndrome, including the overlap of cardiovascular disease with kidney disease, type 2 diabetes, and obesity.

132
132
article thumbnail

Meghan O’Rourke on a medical system not built for chronic illness — and the ‘invisible kingdom’ that could spur change

STAT

When her life was upturned by an accumulating array of confounding health problems, Meghan O’Rourke turned, like so many writers before her, to metaphor. Her body wracked with fatigue was a mound of sand. Her descent into illness was Hemingway’s description of going broke: gradually, then suddenly. The chronically ill patient dejected after fruitless interactions with doctors was nearly invisible, and solitary.

144
144
article thumbnail

Few therapists measure outcomes. A startup's new framework aims to change that

Fierce Healthcare

Two-thirds of patients receiving three months of outpatient therapy will not reach remission, a new analysis of behavioral health therapy outcomes data reveals. | Practitioners can use the framework, known as the Blueprint Quality Index (BQI), to track quality improvement over time, as well as assess the effect of programmatic or infrastructure changes on patient outcomes.

136
136
article thumbnail

What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

article thumbnail

STAT+: FDA clears Verve to begin U.S. study of gene-editing treatment for high cholesterol

STAT

Verve Therapeutics said Monday that it had received clearance from the Food and Drug Administration to conduct a clinical trial in the U.S. of its experimental, gene-editing treatment for a common form of heart disease. The FDA’s action removes a clinical hold on Verve’s CRISPR-based therapy, called VERVE-101, that was placed on it last November.

FDA 143
article thumbnail

Personalized Survivorship Plans for Colon Cancer Patients Receiving Adjuvant Chemotherapy

Drug Topics

Survivorship care for patients with colon cancer should include comprehensive coordination between oncologists, specialists, and primary care providers and include psychological and economic factors in addition to standard health recommendations.

article thumbnail

Opinion: Done right, AI can give patients crucial information on the quality of their care

STAT

Almost as soon as ChatGPT was released to the public, doctors began focusing on how they could harness artificial intelligence to improve patient care. Yet even as AI is providing doctors with increasingly sophisticated data, the information available to patients has stagnated. The stark reality is that there’s far more information available today to guide you in betting a few dollars on the performance of your local sports team than in betting your life on the performance of your local h

article thumbnail

Experiential Education Paves the Way for the Future of Pharmacy Curricula

Pharmacy Times

Innovative experiential learning can provide students with skills necessary to launch successful careers, keeping the pharmacy profession trusted by patients.

132
132
article thumbnail

5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

article thumbnail

STAT+: Health tech investors are getting selective. Expect slow growth, consolidation

STAT

Venture firms backing health tech startups are telegraphing cautious optimism for 2024, advising startups to expect smaller and fewer checks as well as possible market consolidation but not to abandon hope just yet as investments stabilize following a sharp drop-off. As customers — often health systems, payers, or employers — and backers plot how they’ll invest shrinking budgets, they’re increasingly savvy about metrics, investors told STAT.

126
126
article thumbnail

FDA Approves First-of-its-Kind Subcutaneous Infliximab Biosimilar

Drug Topics

Newly approved by the FDA, Celltrion’s infliximab-dyyb (Zymfentra) offers patients with inflammatory bowel disease a more innovative administrative approach to infliximab treatment.

FDA 98
article thumbnail

Henry Ford Health, group practice sued over policy requiring cognition tests for older physicians

Fierce Healthcare

An 84-year-old ophthalmologist has filed a class action lawsuit against Henry Ford Health and its medical group practice over a policy requiring older practitioners to undergo a cognition screen in | Henry Ford Medical Group's policy currently requires those 70 and older to undergo a screening "solely based on age," according to the class action suit filed by an 84-year-old ophthalmologist.

120
120
article thumbnail

With FDA rejection to treat hives disorder, Sanofi and Regeneron's Dupixent suffers rare setback

Fierce Pharma

Regeneron and Sanofi are anxious to bring Dupixent as an answer for chronic spontaneous urticaria (CSU), a severe inflammatory condition that causes hives and deep swelling on or under the skin.

FDA 118
article thumbnail

STAT+: Roivant’s CEO is a star, but even a blockbuster deal can’t escape biotech’s black hole

STAT

Roivant Sciences’ Matt Gline might be this year’s best biopharma CEO, and other thoughts about Monday’s blockbuster deal with Roche — like, why the heck did Roivant’s stock trade down? Gline created $5 billion from $50 million — in less than one year. Regular readers know that every December, I choose a best biopharma CEO.

111
111
article thumbnail

Identifying and Closing Gaps in Preventive Care for Women and Adolescents

Drug Topics

Evidence-based preventive care can improve overall health and decreases illness and death for women and adolescents, but gaps in care caused by barriers still exist.

98
article thumbnail

STAT+: Data on AstraZeneca cancer drug allay safety concerns but treatment still faces questions

STAT

MADRID — Questions about one of AstraZeneca’s key cancer drug candidates — and the dribs and drabs that have come out about its performance — have been dogging the company for months. On Monday, data presented here from a trial of the drug in advanced non-small cell lung cancer provided at least a fuller look. While the results assuaged some of the safety fears that flared when initial information was released over the summer, they only heightened concerns about the d

article thumbnail

Clinical Overview: Preventative Tools for Respiratory Syncytial Virus

Pharmacy Times

RSV can create a problematic infection among children 12 months of age or younger, older adults, and in patients with immunocompromised conditions.

123
123
article thumbnail

STAT+: Results on Novartis prostate cancer therapy could expand its use

STAT

MADRID — Results presented Monday could expand the use of a Novartis therapy for metastatic prostate cancer, moving it from a treatment used after chemotherapy to one with demonstrated benefits beforehand as well. The Phase 3 data, highlighted in a prime session here at the annual meeting of the European Society for Medical Oncology, also amount to another win for cancer therapies designed to deliver radiation directly to tumor cells.

article thumbnail

Medicaid expansion could cover more than 2M additional people

Fierce Healthcare

A new report projects that if states holding out from expanding Medicaid reversed course, 2.3 million people would get access to healthcare.

129
129
article thumbnail

STAT+: In lung cancer, J&J data amount to latest salvo against AstraZeneca

STAT

MADRID — A competition has been brewing between two pharma titans — Johnson & Johnson and AstraZeneca — to gain an edge in the market for targeted lung cancer treatments. A primetime presentation here Monday amounted to the latest salvo. At the annual meeting of the European Society for Medical Oncology, J&J unveiled three studies of its drug Rybrevant in different patient groups with non-small cell lung cancer with EGFR mutations.

111
111
article thumbnail

Watch DSN: Walmart grows HIV-focused specialty pharmacy clinics

Drug Store News

Walmart executive Aleata Postell discusses how pharmacists, technicians and community health workers are coming together to help HIV patients navigate their individual journeys.

article thumbnail

EU authorities fine Boehringer, others for operating drug-ingredient 'cartel'

Fierce Pharma

Five pharmaceutical companies, including the global player Boehringer Ingelheim, have landed in hot water for running a "cartel" to dominate the market for a specific drug ingredient in Europe. | Authorities said the companies agreed to set minimum prices, allocated business and more. Boehringer Ingelheim was hit with the largest fine among the group.

article thumbnail

GNC Health expands virtual healthcare services

Drug Store News

GNC Health now offers low cost virtual health care for urgent conditions, primary care appointments, mental health, physical therapy, $0 prescription medications and more.

110
110
article thumbnail

What does the color of your period mean?

The Checkup by Singlecare

Menstrual blood comes in a variety of colors. In fact, it’s normal to have period blood in various shades of red, pink, and brown. The varied hues can mean different things, too. Learning what the different shades may indicate can help you recognize what’s normal for your body—and when something might be off. Why does period blood have different colors?

article thumbnail

ShopRite shuttering 5 stores in New York

Drug Store News

Wakefern Food’s ShopRite banner has revealed that it will close five stores and gas stations in the metropolitan area surrounding Albany, N.Y., commonly referred to as the Capital Region.

105
105
article thumbnail

With $385M settlement, Indivior closes out long-running Suboxone antitrust case

Fierce Pharma

With a $385 million settlement, Suboxone maker Indivior is moving to wrap up years of antitrust litigation tied to its opioid addiction treatment. | The deal follows previous settlements worth $102 million and $30 million with two other claimant groups.

105
105
article thumbnail

STAT+: Pharmalittle: Roche buys Roivant bowel disease drug for $7.1 billion; AstraZeneca CEO calls report of imminent retirement ‘fake news’

STAT

Good morning, everyone, and welcome to another working week. We hope the weekend respite was relaxing and invigorating because — you know what we will say — the predictable routine of online meetings and deadlines has returned. But what can you do? The world, such as it is, somehow continues to spin. So to cope, we are quaffing cups of stimulation.

96
article thumbnail

ESMO 2023: Janssen reveals data for intravesical delivery system

European Pharmaceutical Review

An intravesical drug delivery system designed to provide sustained local release of gemcitabine into the bladder, has enabled 77 percent of bladder cancer patients (23 out of 30) to achieve a complete response (CR) in the Cohort 2 of the Phase IIb SunRISe-1 study. TAR-200 is indicated for Bacillus Calmette-Guérin (BCG)-unresponsive, high-risk non-muscle-invasive bladder cancer (HR-NMIBC) CIS (carcinoma in situ)-positive in individuals who are ineligible for, or decline radical cystectomy.

article thumbnail

Johnson & Johnson antiviral pill for dengue shows early efficacy

STAT

Want to stay on top of the science and politics driving biotech today?  Sign up  to get our biotech newsletter in your inbox. Today, we see data from ESMO showing that Roche’s alectinib works well in some early stage lung cancers, see our first preventative dengue pill, and more.

FDA 94