Thu.Dec 14, 2023

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Combined Influenza, COVID-19 Vaccines Offer Strongest Protection for Children

Drug Topics

While either vaccine offers some protection, having both vaccines offers the strongest level of protection against hospitalization and severe complications like MIS-C, and death.

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From Fear to Passion: Embracing the Unexpected Journey into Pediatric Pharmacy with Dr. Stephen Small!

Pharmacy Is Right For Me

An Unexpected Path Deciding exactly what you want to do or where you want to go in life is difficult. What if you don’t like where you end up? What if you change your mind? Dr. Stephen Small is a prime example of what it looks like to not only change your mind but to embrace the unexpected. Dr. Small is a pediatric clinical pharmacist specialist but if you had asked him years earlier, he would not have thought that he would end up working with children, “Pediatrics was actually the only specialt

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Trending Sources

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Mediterranean Diet Could Help Reduce Adverse Pregnancy Outcomes

Drug Topics

The mediterranean diet targets inflammation, oxidative stress, and hormonal balance mechanisms, which are also associated with female reproductive outcomes.

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Litfulo From Pfizer Inc

Pharmacy Times

The approval carries the limitation that ritlecitinib should not be used in combination with biologic immunomodulators, cyclosporine, other Janus kinase inhibitors, or other potent immunosuppressants.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Done deal: Pfizer completes $43B acquisition of Seagen, doubling its oncology pipeline

Fierce Pharma

Pfizer’s $43 billion acquisition of Seagen is in the books, the company said on Thursda | It’s a done deal. Pfizer’s $43 billion acquisition of Seagen is in the books, as it becomes the largest M&A transaction in the biopharma industry since AbbVie snatched up Allergan for $63 billion in 2019. The buyout of the antibody-drug conjugate specialist has doubled Pfizer’s pipeline to 60 programs.

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Navigating C. Diff During the COVID-19 Pandemic, The Impact of Antibiotic Usage and Surgeries

Pharmacy Times

Feldman details her experience with C. diff, how the COVID-19 pandemic slowed the timeline of care, and how her surgical history and the use of antibiotics played into the disease’s onset.

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More Trending

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Generic Product News: December 2023

Pharmacy Times

The products include Calcium, Magnesium, Potassium, and Sodium Oxybates Oral Solution, Icatibant Injection, Esomeprazole Magnesium Capsules, and Apremilast Tablets.

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Fees charged by hospitals for colonoscopy procedures 50% higher than surgical centers, study finds

Fierce Healthcare

A new price comparison study finds over 50% higher facility fees for commercially insured colonoscopies performed in hospitals rather than ambulatory surgery centers (ASCs), suggesting that “money | The analysis of commercial payers' price transparency data shows that “money has apparently been left on the table” for employers and consumers, the study's senior author says.

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STAT+: In response to criticism, FDA publishes new database of wayward clinical trial sponsors

STAT

In a bid toward greater transparency, the U.S. Food and Drug Administration earlier this month launched a dashboard containing preliminary notices sent to companies, universities, and researchers that failed to register clinical trials or report study results. The agency has so far sent about 120 so-called pre-notices indicating a clinical trial sponsor or investigator failed to comply with a federal law that requires such steps.

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FDA Approves Updated Label for Bempedoic Acid, Ezetimibe Tablets

Pharmacy Times

The update also removed the maximally tolerated qualifier for statin use and the statement that said morbidity and mortality was not yet determined.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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STAT+: Sanders blames food companies for diabetes epidemic

STAT

WASHINGTON — Sen. Bernie Sanders (I-Vt.) has a new corporate target: the food industry. Sanders held a hearing today on diabetes that implicated both the food and drug industries in what the American Diabetes Association estimates is a $413 billion annual cost to the health care system. That’s up 27% over the past six years, he said, and he warned that new weight loss drugs could send health care spending to the stratosphere.

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Slideshow: Examining the Treatment Landscape for Chronic Lymphocytic Leukemia

Drug Topics

Six posters presented at the 65th American Society of Hematology Annual Meeting and Exposition looked at how treatments are impacting care for this patient population.

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North Carolina attorney general sues HCA for lapses at Mission Health

STAT

North Carolina’s attorney general alleges in a new lawsuit that HCA Healthcare is violating the terms of the agreement that allowed it to buy Mission Health, a formerly nonprofit health system. In the complaint filed Thursday , attorney general Josh Stein said HCA, the country’s largest for-profit hospital chain, is not providing the quality, consistent emergency and cancer care that it committed to delivering across Mission’s six western North Carolina hospitals.

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Oracle's Q2 revenue comes up short dragged by Cerner business, slower cloud growth

Fierce Healthcare

Oracle's second-quarter revenue fell short of analysts' expectations, dragged down by its Cerner business and slowing cloud growth. | Oracle is using its tech muscle to add new capabilities to the Millennium EHR, chairman Larry Ellison said. "We are going after a much larger market than Cerner was. We expect Cerner to be a growth story," he told investors during Oracle's Q2 earnings call.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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STAT+: Jay Bradner, former Novartis research leader, to head up Amgen’s scientific efforts

STAT

Jay Bradner, a former top research leader at Novartis, is joining Amgen as its new chief scientific officer, the California company announced Thursday.   Bradner is taking over for Amgen veteran David Reese in the role. Reese is becoming the company’s chief technology officer. “For more than 40 years, Amgen’s focus on innovation has enabled us to deliver life-changing medicines to patients suffering from serious diseases around the world,” Robert Bradway, Am

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3 Signs the pharmacy ecosystem is poised for a movement. Are you ready?

Drug Topics

Pharmacy is positioned for growth like never before, and to meet this rapid increase, pharmacies must adopt innovative methods to keep up with the rising demand. Where do your pharmacists spend most of their time? If your answer is "counting pills," it might be time to dig deeper and ask yourself where you want them to be spending their time.

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Biden administration flags dozens of pharma companies to pay Medicare rebates for 'outrageous' price hikes

Fierce Healthcare

The Biden administration is cracking down on pharmaceutical companies as part of its price-fighting measures under the Inflation Reduction Act. | The Biden Administration announced Thursday a list of 48 Part B drugs with prices that rose faster than the rate of inflation in the final quarter of 2023. Here's what they plan to do now.

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FDA Approves Elfornithine for the Treatment of High-Risk Neuroblastoma in Adult, Pediatric Patients

Pharmacy Times

This is the first FDA approval for a therapy intended to reduce the risk of relapse in patients with high-risk neuroblastoma.

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Bluebird signs major coverage deal for sickle cell gene therapy Lyfgenia, easing some price concerns

Fierce Pharma

Despite the high list price of Lyfgenia, bluebird has signed a large reimbursement deal for the sickle cell disease (SCD) gene therapy less than a week after its

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Researchers Design Flu Vaccine With Improved Protection From Influenza A Strains

Pharmacy Times

The results found that the M2e nanoparticle injection could efficiently protect individuals from influenza A viruses.

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STAT+: Amputees have better balance, less pain after electrical stimulation, study finds

STAT

For years, Lauren Gavron relied on oxycodone to quiet the pain in her missing lower left limb. But she hated the fog that came with it, preventing her from feeling comfortable enough to drive. When researchers at the University of Pittsburgh delivered electric jolts to her spine in 2021, the Duquesne, Pennsylvania resident was shocked to feel that pain temporarily melt away — and to feel sensation in her prosthetic foot, improving her walk and balance.

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Healthcare industry celebrates, honors NACDS’ 90th anniversary, retail pharmacies

Drug Store News

The healthcare industry joined together Wednesday night in New York City to honor and celebrate NACDS’ 90th anniversary, while also paying tribute to pharmacy retailers.

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Opinion: In mifepristone case, the Supreme Court must affirm the FDA’s authority. Medical innovation is at risk

STAT

On Wednesday, the Supreme Court announced it will soon weigh in on a case that challenges how the Food and Drug Administration regulates mifepristone , a drug it approved almost 25 years ago that is used to terminate pregnancy. The case, the Alliance for Hippocratic Medicine v. FDA, is disguised as a dispute over safety. In reality, it’s about whether the courts will go along with overturning, for political reasons, the authority of the FDA as the scientific arbiter of approval of ne

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Understanding the evidence used in drug product withdrawals

European Pharmaceutical Review

In the ever-evolving landscape of regulatory decisions, the quest for safeguarding public health remains paramount. Decisions to remove medicines from market are not taken lightly and are often based upon all evidence available to inform a benefit/risk balance. This evidence can come from a range of sources, such as randomised controlled trials (RCTs), observational studies, and spontaneous reporting.

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Opinion: Europe’s lessons for the U.S. on how to cover weight loss drugs

STAT

It’s no secret that the obesity epidemic in the United States has reached alarming levels, with rates surpassing 40% of the population. Despite a robust focus on wellness and exercise in the media, post-pandemic America continues to rank among the global leaders in obesity rates. Estimates indicate that treating obesity will be expensive, but those sums pale in comparison to the estimated direct and indirect costs of $1.7 trillion that obesity places on the U.S. health care system today.

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Speakers at DSN's Industry Issues Summit discuss big trends, such as AI, health equity, the future of pharmacy

Drug Store News

Drug Store News held its 25th annual Industry Issues Summit in New York City on Dec. 13, where industry leaders weighed in on a myriad of challenges and opportunities.

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US WorldMeds' Iwilfin bags FDA nod as 1st oral maintenance treatment for high-risk neuroblastoma

Fierce Pharma

While existing neuroblastoma treatments can help patients achieve remission, sustaining that remission has proven tricky. But now, patients and doctors have a new oral option. | The U.S. FDA has approved US WorldMeds’ Iwilfin—also known as eflornithine—as a new oral maintenance therapy for high-risk neuroblastoma. The drug, cleared in 192 mg tablets, is indicated to cut the risk of relapse in kids and adults with high-risk neuroblastoma who’ve had at least a partial response to prior treatment.

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STAT+: Why FDA product recalls have spiked in recent years

STAT

Either American products are getting worse, or scrutiny over their safety is getting tougher. Whichever the case, product recalls by the Food and Drug Administration and the Consumer Product Safety Commission (CPSC) more than doubled between 2018 and 2022, according to new research published on Wednesday by life sciences software company MasterControl.

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Is amoxicillin good for a UTI?

The Checkup by Singlecare

If you’ve ever felt the painful symptoms of a urinary tract infection (UTI), it’s likely you want relief fast. You’re not alone—UTIs are common. They occur when bacteria like Escherichia coli (E. coli) infect the urinary tract organs, including the urethra (urethritis), bladder (cystitis), ureters, and kidneys (pyelonephritis). Most urinary tract infections are caused by bacteria and are treated with antibiotics.

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Patient Centric Diabetes Care

PharmExec

A discussion of the current standard for diabetes care and how the importance of patient centricity, including addressing patient's mental health, are imperative to the future of the space.

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Listen: FTC v. biotech, Pfizer’s kitchen sink, & Vertex’s future

STAT

Is no one safe from the FTC? Has Pfizer bottomed out? And is biotech finally back? We cover all that and more this week on “The Readout LOUD,” STAT’s biotech podcast. First, we delve into the fallout over the FTC’s move to block what looked like a humdrum biotech deal between Sanofi and Maze Therapeutics, a surprising twist that leaves an unanswered question.

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Study Highlights Need for Pharma Industry to Address Stigmatization of Acne

PharmExec

JAMA Network study evaluates current attitudes toward individuals with acne with a call for pharma companies to focus efforts on helping to overcome these stigmas.

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Is it time to worry about Moderna?

STAT

Want to stay on top of the science and politics driving biotech today?  Sign up  to get our biotech newsletter in your inbox. Hello, everyone. Damian here with the fallout from Pfizer’s downbeat update, a new entrant in obesity research, and an orthogonal CRISPR business.

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Alternative Funding Programs Affect Our Most Vulnerable Patient Populations

Pharmacy Times

AFPs limit access to provider-prescribed specialty medications.

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