Wed.Sep 13, 2023

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CDC’s ACIP Votes in Favor of Universal Recommendation for 2023-2024 Monovalent COVID-19 Vaccines

Pharmacy Times

The CDC emphasized the need for protein-based vaccine options in endorsing a vote by the Advisory Committee on Immunization Practices for the universal recommendation of the 2023-2024 monovalent, XBB containing COVID-19 vaccines.

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They’re immigrants, farmworkers, and new moms. And they’re facing postpartum depression at higher rates

STAT

Over more than a decade working with immigrant farmworkers in the public clinics of the Santa Clara River Valley, Rosemary Hernandez has seen many new moms struggle during the postpartum period. Some were separated from their families in Mexico. Others’ husbands or boyfriends had to head straight back to work picking fruit after the baby arrived.

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Patients With Cancer Using Nonmedical Stimulants Can Continue Using Opioids, Regardless of Prognosis

Pharmacy Times

Experts agreed that it was appropriate for patients who use methamphetamine or cocaine to continue opioid use if clinician monitoring was increased and tapering was avoided.

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Opinion: STAT+: The IRA needs changes to better support patients with rare diseases

STAT

This time last year, members of Congress were working around the clock to draft and pass the Inflation Reduction Act. One of their goals was to address government spending on health care. But they specifically didn’t want to discourage research into rare disease treatments, so they exempted some of these so-called orphan drugs from the law. Unfortunately, the exemptions aren’t working as intended.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Oracle CEO warns Cerner EHR business facing 'near-term' headwinds for revenue growth

Fierce Healthcare

Oracle shares fell 13% Tuesday as the software giant's near-term revenue forecast was weaker than Wall Street analysts expected. | Oracle chairman and CTO Larry Ellison told investors Monday that the company is working to modernize the Cerner EHR platform using an application code generator to enhance the software "one piece at a time." "On the business side of things, we think the Cerner business is going to get stronger and stronger," Ellison said.

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Opinion: PEPFAR, one of the greatest public health inventions of our time, is at risk

STAT

In the clinic where I work, I met a patient the other day whom I might not have 20 years ago. He was from Uganda. Recently, he had moved to my small university town a few hours outside of Toronto. He was eager and bright. As we spoke, I was struck by how coolly he handled himself in the face of a great adversity. He told me that during an emergency medical procedure, in a rural village where he was doing fieldwork, he contracted HIV.

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STAT+: How Silicon Valley’s hospital whisperer bridges the gap between startups and health systems

STAT

SAN FRANCISCO — As part of one of the tech industry’s most revered venture funds, Daryl Tol is very familiar with fast-paced, sometimes overblown pitches from go-getter founders, lining up at happy hours and investor panels to score just a few minutes of face time. A chance meeting, or an email to the right person, could propel pie-in-the-sky ideas into billion-dollar, global businesses.

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PBM Transparency Legislation Expected to be Brought by Congress

Drug Topics

Over the last two legislative sessions, many bills have been introduced in the both the House and the Senate, but there are four bills that are important to watch.

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STAT+: Akili abandons prescription business model, to lay off 40% of workers

STAT

Akili Interactive, which in 2020 made waves by receiving Food and Drug Administration clearance for its video game that improves symptoms of ADHD in children, on Wednesday announced it would reorient its business around selling its products directly to users over the counter, rather than by prescription. In connection with the move away from prescription sales, Akili will reduce its workforce by 40%, which the company projects will extend its runway into the second half of 2025.

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Bispecific Antibodies Achieve High Response Rates, Tolerable Adverse Effects in Multiple Myeloma

Pharmacy Times

Bispecific antibodies have offered a new treatment approach in relapsed/refractory multiple myeloma, with promising results in preclinical studies for multiple cancers and hematological malignancies.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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New tech, operating challenges pushing providers to spend more on IT, software

Fierce Healthcare

Healthcare providers have upped their spending on IT and software, a shift leaders said is driven by the new technologies, labor challenges and other financial pressures on their organizations, acc | Nearly 80% of polled provider executives report higher tech spending during the past year, and about three quarters say their numbers will grow over the next 12 months.

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It's unanimous: FDA panel says decongestant drug phenylephrine does not work

Fierce Pharma

For decades, hundreds of oral decongestant products containing phenylephrine have been available in the United States over the counter. | For decades, hundreds of oral decongestant products containing phenylephrine have been available in the United States over the counter. But on Tuesday, an FDA advisory committee agreed by a 16-0 vote that the ingredient does not work.

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The legal battle over drug price negotiations is just getting started

Fierce Healthcare

Pharmaceutical companies are waging war against federal agencies over one of the Inflation Reduction Act’s major provisions allowing Medicare to negotiate 10 drugs to reduce out-of-pocket costs for | Legal experts question whether the Inflation Reduction Act is within its rights to enforce its drug pricing negotiation provision.

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STAT+: FDA panel endorses Alnylam’s heart drug — after picking apart its supporting data

STAT

A group of advisers to the Food and Drug Administration voted in favor of Alnylam Pharmaceuticals’ treatment for a debilitating heart disease Wednesday, but only after a day-long debate challenging whether the drug’s modest observed effects were actually meaningful for patients. The group of independent experts voted 9-3 that the benefits of Alnylam’s drug, called patisiran, outweighed its risks for patients with ATTR-CM , a progressive disease that leads to fatal heart fail

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Could contentious payer-provider negotiations become the post-COVID norm?

Fierce Healthcare

Providers are under significant pressure as the COVID-19 pandemic effects wear on, so it shouldn't come as a surprise that they're pushing payers for more in contract negotiations. | Providers are under significant pressure as the COVID-19 pandemic effects wear on, so it shouldn't come as a surprise that they're pushing payers for more in contract negotiations.

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Multiple Lisdexamfetamine Dimesylate Generics for ADHD in Children Approved by FDA

Drug Topics

In addition to approving these generics for children, adolescents and adults with ADHD, the generic chewable tablets and capsules are also approved for adults with moderate to severe binge-eating disorder.

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Senators Joe Manchin, Marco Rubio introduce bill to make violence, threats against hospital workers a federal crime

Fierce Healthcare

Senate legislators have rolled out a bipartisan, industry-backed bill that would make assault or intimidation of hospital workers a federal crime. | The bipartisan Safety from Violence for Healthcare Employees Act has industry support and follows similar legislation brought in the House.

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Managing Specialty Drug Costs Among Many Challenges Ahead for Health Plans

Drug Topics

Matthew Lee, vice president of sales and marketing at MedOne, led a discussion about trends in care management from a PBM and health perspective.

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AACR Releases Annual Cancer Progress Report, Urges Expansion in Cancer Research

Pharmacy Times

AACR has urged Congress to provide billions more in funding for cancer research, prevention efforts, and expedited review of cancer-related medical products.

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Moderna CEO expects endemic COVID vaccine market will take ‘a few years’ to fully develop

Fierce Pharma

Moderna has spent the last several years riding the ups and downs of the COVID-19 pandemic. | Moderna CEO Stéphane Bancel is optimistic that the company will beat the low end of its $6 billion to $8 billion COVID vaccine sales estimate for 2023. But his optimism comes as Moderna reportedly eyes manufacturing cuts as it shifts to an endemic market response.

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Neuraminidase Inhibitor, Polymerase Inhibitor Use for Influenza Treatment Continues, Other Methods Considered

Pharmacy Times

While monitoring influenza virus resistance as it develops, researchers are prioritizing further investigations to decrease the risk of resistant strains.

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Digital health, health IT funding slumped in Q2, but some bright spots remain, Pitchbook finds

Fierce Healthcare

Digital health and health IT funding continued to decline in the second quarter of 2023, according to two new reports from Pitchbook. | Digital health VC deal flow hit a new low, though several strong segments persisted. VC deals in health IT also dropped quarter over quarter but are beginning to recover from their low in 2022.

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Moderna looks to scale back manufacturing for COVID booster to cope with falling demand: Reuters

Fierce Pharma

While the FDA and the Centers for Disease Control and Prevention (CDC) have signed off on updated COVID vaccines for this season, Moderna is already reportedly preparing for lower demand for its sh | Moderna is speaking with its manufacturing partners to scale back production of its mRNA COVID vaccine to adapt to the endemic phase of the disease, Moderna’s president and R&D head, Stephen Hoge, said, Reuters reports.

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Watch DSN: Life Sciences touches on importance of pharmacy state boards

Drug Store News

Lucas Morgan, partner at Frier Levitt’s Healthcare and Life Sciences Litigation Department, shares important information pharmacists need to know to protect their businesses.

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Ferring begins bladder cancer gene therapy rollout through focused program

Fierce Pharma

After securing approval at the end of last year for a potential alternative to bladder removal in certain bladder cancer patients, Ferring Pharmaceuticals has given the gene therapy Adstiladrin to | While it scales up manufacturing, the company is rolling out its Adstiladrin through an early, focused program at certain clinics. The program will also be used for a real world evidence study.

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Beauty is in the brow

Drug Store News

Billion Dollar Beauty, founded by Natalie Plain, began by addressing needs in the brow space and expanded to tackle the inefficient makeup palette category.

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Can you use metronidazole for cats?

The Checkup by Singlecare

Has your cat been having diarrhea for a while? As a pet owner, this can be a lot of trouble. When you’ve tried your best to control it without getting results, that’s when antibiotics become an integral component of pet care. Among the go-to treatments is using metronidazole for cats to treat gastrointestinal infections like diarrhea. Metronidazole is an antibiotic and antiprotozoal sold under the brand name Flagyl and prescribed to humans and their pets.

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Despite FDA doubts, Alnylam wins expert backing for Onpattro expansion into rare heart disease

Fierce Pharma

After Alnylam faced FDA doubts about its bid to expand RNA-silencing drug Onpattro into a rare heart disease called transthyretin amyloidosis cardiomyopathy (ATTR-CM), the company has picked up key | An FDA advisory committed voted in favor of Alnylam's bid to expand its RNA-silencing drug Onpattro into the rare heart disease called ATTR-CM. But comments at Wednesday’s panel suggest the drug could carry a disadvantage in its upcoming clash with Pfizer.

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MorningRX: September 13, 2023

Drug Topics

The CDC weighs in on updated COVID-19 vaccines, the FDA says phenylephrine is ineffective, and heath care workers in California get a pay raise.

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COVID-19 Revealed How a Lack of Care for Seniors Affects Us All

Pharmacy Times

Failing to protect the elderly from disease has consequences beyond nursing homes.

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Elevance Health research outlines ways health plans can fight loneliness in MA beneficiaries

Fierce Healthcare

Elevance Health research outlines ways health plans can fight loneliness in MA beneficiaries fdiamond Wed, 09/13/2023 - 13:26

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4 ways to get rid of the chills

The Checkup by Singlecare

You’re lounging on the couch watching your favorite TV show when, all of a sudden, you notice you’re cold. And it’s not a regular cold; it’s a bone-deep freeze that causes you to shiver. Maybe your teeth chatter or your skin goes pale. If this has ever happened to you, you most likely have experienced the chills. Chills (otherwise known as shivering) are the rapid contracting and releasing of muscles to regulate the body’s internal temperature, according to Payal Sud , MD, the associate chair of

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Medications That Cause Low Blood Pressure (Non-Antihypertensives)

Med Ed 101

One of the most common medication review requests I get from clinical staff in long term care and assisted living facilities is identifying medications that may be contributing to falls. Identifying low blood pressure as a potential contributing factor is usually pretty obvious. It is also obvious to reduce antihypertensive medications (ACEs, ARBs, Diuretics, Calcium […] The post Medications That Cause Low Blood Pressure (Non-Antihypertensives) appeared first on Med Ed 101.

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Meet the 2023 Foya Supply Chain and Social Impact Categories Winner: SERUM Institute of India Pvt. Ltd.

ISPE

Meet the 2023 Foya Supply Chain and Social Impact Categories Winner: SERUM Institute of India Pvt. Ltd. Logan Thomas Wed, 09/13/2023 - 11:09 iSpeak Blog iSpeak Meet the 2023 Foya Supply Chain and Social Impact Categories Winner: SERUM Institute of India Pvt. Ltd. Marcy Sanford 13 September 2023 Facility of the Year Award (FOYA) Winners in the Supply Chain category exemplify novel application of principles, systems, and management tools aimed at improving operational speed, robustness, and respon