Tue.Jan 23, 2024

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City of Boston Sues Major PBMs Over Role in Opioid Crisis

Drug Topics

The lawsuit claims several pharmacy benefit managers, including Express Scripts and OptumRx, collaborated with manufacturers in “deceptive” and “dangerous” marketing.

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Abortion funds run short of money as demand soars and donations fall

STAT

The head of the Abortion Fund of Ohio had a sinking feeling as she looked at its end-of-year finances last month. The fund had paid out $1.5 million in 2023 to help close to 4,400 patients get abortions — up from 1,175 the year before — and the pace wasn’t sustainable. If the fund didn’t take a pause for a few weeks, she feared it would run out of money and have to close for good.

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Trending Sources

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Circadian Disruption May Be Significantly Linked to Chronic Kidney Disease

Pharmacy Times

Increased waist circumference and high blood pressure can disrupt circadian rhythm, which can increase risk of progression to poor renal outcomes.

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Mammograms are less effective for women with dense breast tissue. Medical experts disagree on what to do about it

STAT

Millions of American women over age 40 receive regular mammograms to screen for breast cancer. About half of them turn out to have dense breast tissue — which makes screening significantly more complicated. “It’s kind of a double whammy because dense breast tissue not only makes cancers harder to find, but people with denser tissue are more likely to get breast cancer,” said Laurie Margolies, a radiologist and vice chair for breast imaging at Mount Sinai.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Most rural hospitals aren't offering labor and delivery services, forcing mothers to travel

Fierce Healthcare

Over half of the country’s rural hospitals aren’t offering labor and delivery services, and many of those that are could soon be forced to end maternity care due to financial losses, according to t | Many rural facilities that do still deliver are facing financial struggles that could force a shutdown, the Center for Healthcare Quality and Payment Reform wrote in a new report calling for stakeholders to pressure private insurers for higher rural hospital payments.

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Public Health Matters: A Review of Upcoming Digital Health Technology Products

Pharmacy Times

Public Health Pharmacist discussed wearable technology and AI assisted technology that was displayed at the 2024 Consumer Electronics Show

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More Trending

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New Unite Us-driven payments pilot to reimburse social service organizations in Brooklyn

Fierce Healthcare

Community Care of Brooklyn (CCB), a network of more than 1,000 Brooklyn-based providers and community-based organizations, has teamed up with Unite Us to track and reimburse for social services.

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STAT+: Sanofi scoops up U.S. biotech Inhibrx for up to $2.2 billion as it seeks to bolster pipeline

STAT

LONDON — In a bid to expand its pipeline of inflammation-targeting drugs, Sanofi said Tuesday it was acquiring California-based Inhibrx in a deal worth up to $2.2 billion. The core of the deal is Inhibrx’s experimental therapy for AATD, a disease that progressively damages the lungs and liver. The medicine, INBRX-101, is designed to reduce inflammation and stave off further damage to the tissue.

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‘Jiffy Lube of — of therapies, yes’: Complex Sentences Can Generate a Higher Brain Response Than Simple Sentences

Pharmacy Times

New sentences that had different linguistic properties than traditional sentences drove brain activity, according to the study authors.

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HbA1c Over 6% Associated With Higher Diabetes Risk in Adolescents

Drug Topics

Compared with an HbA1c level of 5.5%, adolescents with overweight or obesity were 72 times more likely to have type 2 diabetes if their HbA1c was 6.3% to 6.4%.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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Chlorine-Treated Drinking Water Might Change Species Diversity in Gut Microbiota

Pharmacy Times

Findings from a recent murine model may translate to the human gut microbiome, but assessing chlorine’s effects on the gut microbiome remains complex.

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Price transparency startup Turquoise Health picks up $30M series B funding

Fierce Healthcare

Price transparency data startup Turquoise Health clinched $30 million in fresh funding to build out its capabilities. | Price transparency data startup Turquoise Health clinched $30 million in fresh funding to build out its capabilities. The company is building an AI-based platform to support payer and provider contract management, consumer transparency compliance and advanced platform-based analytics.

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Fertility Preservation May Not Need to Delay Breast Cancer Treatment

Pharmacy Times

Patients should work with clinicians to discuss controlled ovarian stimulation because there is still limited research.

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Wyden seeks details from brokers in probe of MA marketing tactics

Fierce Healthcare

The Senate Finance Committee sent letters to multiple insurance marketplaces, seeking additional details on the marketing strategies they use to reach potential Medicare Advantage enrollees. | The Senate Finance Committee sent letters to multiple insurance marketplaces, seeking additional details on the marketing strategies they use to reach potential Medicare Advantage enrollees.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Take the hybrid road to bring clinical trials to patients

pharmaphorum

Bringing clinical trials to patients has become easier with the advent of digital technologies and decentralised clinical trials (DCTs). Learn how the hybrid approach combining traditional and digital methods can benefit patients and advance medical research.

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Genmab loses appeal in Darzalex royalties arbitration case against Johnson & Johnson

Fierce Pharma

While sales for Johnson & Johnson’s Darzalex continue to boom—as the company reported in its quarterly earnings presentation on Tuesday—the pharma major got more good news about its blockbuster | An appeal arbitrator has rejected Genmab’s claim that it is due additional milestone and royalty payments from Johnson & Johnson for Darzalex. The Danish biotech was hoping to overturn a 2-1 ruling in a second arbitration between the companies over Darzalex royalties.

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NICE backs two AIs for stroke diagnosis in NHS

pharmaphorum

Two artificial intelligence-powered software tools – e-Stroke and RapidAI – have been recommended for use in the NHS to help detect stroke from CT brain scans by NICE. The health technology assessment (HTA) agency said there is some evidence that people admitted to hospital with a suspected had faster or better access to treatment after using the software, although for now it is unclear whether that was a direct consequence of the digital technology.

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J&J, Legend's Carvykti bid for earlier multiple myeloma use will face FDA adcomm

Fierce Pharma

Early evidence showing Carvykti’s potential to prolong patients’ lives in an earlier multiple myeloma setting didn’t save Johnson & Johnson and Legend Biotech’s CAR-T medicine from a public int | Early evidence showing the drug's potential to prolong patients' lives didn't save Johnson & Johnson and Legend Biotech's Carvykti from a public interrogation by the FDA.

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Generic Product News: January 2024

Pharmacy Times

The products include Loteprednol Etabonate Ophthalmic Suspension, Teriparatide Injection, Allopurinol Tablets, and Sitagliptin Tablets.

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Johnson & Johnson inks $700M deal to resolve talc consumer protection claims from 42 states

Fierce Pharma

After failing to resolve a mountain of talcum-powder lawsuits through two unsuccessful bankruptcy attempts, Johnson & Johnson has agreed to a $700 million settlement that would free the company | After failing to resolve a mountain of talcum-powder lawsuits through two unsuccessful bankruptcy attempts, Johnson & Johnson has agreed to a $700 million settlement that would free the company from some consumer protection claims—and a small part of the talc litigation that it faces.

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Opinion: It’s time to remove skin color from the Apgar Score for newborns

STAT

In medicine, inertia can be a strangely powerful force, but Virginia Apgar never succumbed to it. She brought incredible energy to her work in anesthesia, neonatology, and dysmorphology (the study of birth defects) and questioned the status quo when she thought it might save lives. With gratitude for her tireless work, we have reevaluated the eponymous health assessment Apgar developed more than 70 years ago and concluded that one of its components — skin color — should be abandone

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Do over-the-counter muscle relaxers work?

The Checkup by Singlecare

OTC muscle relaxers | Benefits | Side effects | OTC vs. Rx Have you ever fallen asleep in an awkward position and woken up with a stiff neck? It hurts or is almost impossible to turn to one side or another. Or maybe you’ve done a hard day of physical work and woke up the next morning with spasms in your lower back? Spasms are those painful, involuntary twitches in your muscles that typically result from an injury or overexertion.

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Sanofi snaps up Inhibrx and its rare disease drug for $2.2bn

pharmaphorum

Sanofi agrees $2.2bn deal to buy California biotech Inhibrx and its long-acting therapy for rare disease AATD, which causes life-threatening emphysema.

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Albertsons opens call for diverse-owned brands for annual supplier diversity program

Drug Store News

The application process is open to diverse-owned suppliers, which include small and mid-size businesses that are at least 5% owned, controlled and operated by minorities, veterans or people with disabilities.

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Trial raises hopes for simple Alzheimer’s blood test

pharmaphorum

Study finds evidence that an AlZpath immunoassay for phosphorylated tau could deliver an effective blood test for Alzheimer's, paving the way for screening and early treatment

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What are the side effects of black seed oil?

The Checkup by Singlecare

For thousands of years, black seed, known also as black cumin and black caraway, has been used as an herbal remedy in traditional medicine. Presently, science is still trying to prove black seed oil’s potential benefits and therapeutic role in modern medicine, and of equal importance, research is needed on its safety. Preliminary studies have fueled hope for its use in various health conditions , including allergies , infertility , high blood pressure , diabetes , cancer, and weight loss for obe

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Lilly trumpets early success with deafness gene therapy

pharmaphorum

Eli Lilly’s gene therapy for otoferlin-related deafness has restored the hearing of the first child enrolled in its ongoing phase 1/2 trial

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Will new therapeutic agent replace antibodies for bacterial detection?

European Pharmaceutical Review

As a tool for detecting and identifying bacteria, aptamers are a promising new class of synthetic nucleic acid molecules that can be used to detect and treat of pathogenic bacteria. With the ability to be developed against a whole bacterium, a microbial toxin, or some proteins, for some bacteria, “aptamers against pathogens can not only supplement the deficiency of antibodies but can also enrich the aptamer database to develop efficient analytical regents”, according to a paper published in the

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Walgreens Boots Alliance reportedly exploring $4B plus sale of Shields Health Solutions

Drug Store News

The specialty pharmacy business could be valued at more than $4 billion in a sale, per a Bloomberg report, which cited people familiar with the matter.

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Using Blockchain to Minimize Consumers’ Risk Aversion Toward Generic Drugs

Pharmaceutical Commerce

Study describes how a game theoretic model can successfully analyze how adoption of blockchain technology can reveal quality information.

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Veterans Health Administration employs far less administrative staff than private health sector, study finds

Fierce Healthcare

The healthcare system’s private sector could learn a thing or two about efficiency from the government’s Veterans Health Administration, which employs about 30% less administrative staff across cli | The government health program's simplified payment system helps keep its payroll lean, as opposed to a private sector that employs hundreds of thousands more to secure or enhance its revenues, researchers wrote in JAMA Network Open.

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Club92 debuts at Dollar General

Drug Store News

Slatkin + Co’s new line of accessible luxury home fragrance created by “the King of Home Fragrance” Harry Slatkin is debuting exclusively at Dollar General.

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Fixing the inequity of drug access outside of the US

pharmaphorum

In this new episode of the pharmaphorum podcast, web editor Nicole Raleigh welcomes guest Cem Zorluhar, CEO of Er-Kim Pharmaceuticals, for a conversation on antimicrobial resistance (AMR) and what the biotech industry should be focussing on in order to address this critical issue outside of the West.

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Dysbiosis in the Gut Microbiome May Lead to Development of Various Liver Diseases

Pharmacy Times

There may be a pathophysiological basis for therapy relating to the to the gut-liver axis.

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