pharmaphorum

OCTOBER 13, 2021

The Gastrointestinal Cancer Drug Development Summit is the only biopharma-led conference dedicated to identifying and progressing therapeutic opportunities in targeted and immunotherapies, ADCs, and precision oncology to address the large unmet clinical need in GI cancers. Register for your FREE ticket here: [link].

Immunization 52

Immunization 52

Pharmaceutical Technology

JUNE 10, 2023

Pimitespib is under clinical development by Otsuka Pharmaceutical and currently in Phase I for Metastatic Lung Cancer. According to GlobalData, Phase I drugs for Metastatic Lung Cancer does not have sufficient historical data to build an indication benchmark PTSR for Phase I. It is a small molecule administered orally.

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Chemotherapy 40

Pharmaceutical Technology

JUNE 10, 2023

Pimitespib is under clinical development by Otsuka Pharmaceutical and currently in Phase I for Metastatic Lung Cancer. According to GlobalData, Phase I drugs for Metastatic Lung Cancer does not have sufficient historical data to build an indication benchmark PTSR for Phase I. It is a small molecule administered orally.

Chemotherapy 40

Chemotherapy 40

The Checkup by Singlecare

FEBRUARY 1, 2024

Estrogen is also a part of the body’s regulatory processes in gastrointestinal , skeletal , cardiovascular, and central nervous systems. Phytoestrogens can negatively impact individuals, especially women with a history of estrogen-sensitive cancers. Additional research demonstrated a protective effect of red wine on cancer cell growth.

Mayo Clinic 95

Mayo Clinic Compounding FDA 95

European Pharmaceutical Review

JULY 5, 2022

Stomach cancer, also known as gastric cancer, is the fifth most common type of cancer worldwide – and the third most common cause of death from cancer. Stomach cancer, also known as gastric cancer, is the fifth most common type of cancer worldwide – and the third most common cause of death from cancer.

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Chemotherapy Dosage Labelling Compounding 90

The People's Pharmacy

JUNE 15, 2023

But new research on the alpha-gal meat allergy suggests that the dominant symptoms, sometimes the only symptoms, may be gastrointestinal. She specializes in gastroenterology, colon cancer prevention, C. He is medical director of the UNC Allergy & Immunology Clinic at Eastowne.

Research Laboratories 96

Research Laboratories Immunization 96

pharmaphorum

JULY 6, 2021

A peptide vaccine developed by Australia’s Imugene has reduced tumour size in around half of patients with HER2-positive gastric or gastroesophageal junction (GEJ) cancer in a phase 2 trial. HER-Vaxx is a B-cell activating cancer immunotherapy that consists of several B cell epitopes derived from the extracellular domain of HER2.

Vaccines 118

Vaccines Chemotherapy Immunization 118

pharmaphorum

AUGUST 2, 2022

AbbVie and Sosei Heptares will initially focus on developing up to three GPCR-modulating small-molecule drugs to the point at which they are ready to start clinical trials in humans, whereupon AbbVie has opt-in rights to take them further. The new agreement follows earlier alliances including one worth up to $2.6

Immunization 97

Immunization 97

European Pharmaceutical Review

JANUARY 23, 2023

For the first time, a clinical study in the first-line setting for mPDAC demonstrated superior overall survival (OS) and progression-free survival (PFS) for an investigational regimen when compared to standard of care treatment with nab-paclitaxel and gemcitabine.”

Chemotherapy 91

Chemotherapy Labelling FDA 91

European Pharmaceutical Review

NOVEMBER 17, 2022

In pre-clinical studies, this binding interaction caused cancer cell death by activating antibody-dependent cellular toxicity and complement-dependent cytotoxicity immune system pathways. Gastric and GEJ cancers still have very limited treatment options available for patients with an advanced diagnosis.”. expression in ? “I

Immunization 82

Immunization Hospitals 82

The Checkup by Singlecare

APRIL 14, 2024

Ibuprofen can cause gastrointestinal irritation, ulcers, and bleeding, particularly when taken at high doses or for prolonged periods,” he says. When it comes to ibuprofen drug interactions , the list from the Mayo Clinic is quite lengthy. Take note of any gastrointestinal or kidney problems before taking ibuprofen, too. “I

Mayo Clinic 98

Mayo Clinic Labelling FDA 98

Pharmaceutical Technology

FEBRUARY 23, 2023

Buparlisib hydrochloride is under clinical development by Adlai Nortye Biopharma and currently in Phase II for Mantle Cell Lymphoma. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

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The Checkup by Singlecare

AUGUST 11, 2023

Experts suggest combining alcohol and ibuprofen can raise the risk of serious side effects, including kidney damage and liver problems and gastrointestinal bleeding. According to the Cleveland Clinic, ibuprofen is typically recommended for short-term use only as long-term use carries health risks.

Mayo Clinic 97

Mayo Clinic Compounding Labelling 97

European Pharmaceutical Review

NOVEMBER 4, 2022

Despite advances with targeted and immuno-oncology therapies, chemotherapies remain a cornerstone of cancer treatment for many tumour types – a reflection of their significant anti?tumour They are widely used to treat a variety of solid tumours, including prostate, lung, ovarian and breast cancer. tumour effects.

Chemotherapy 88

Chemotherapy FDA Hospitals Packaging 88

pharmaphorum

JANUARY 12, 2021

Boehringer Ingelheim has signed a strategic collaboration with UK biotech Enara Bio, focused on finding ways to fight cancer using “dark antigens” in a deal worth up to €876 million ($1.07bn). This makes them good targets for targeted therapies that will attack cancer cells while leaving healthy cells alone.

Vaccines 80

Vaccines Immunization 80

European Pharmaceutical Review

MARCH 4, 2024

This growth is accompanied by a substantial number of clinical trials, with close to 20,000 active investigations, involving about 9,500 new biologic treatments. These actions occur at both the delivery site and other systemic locations, thereby promoting an immunogenic response that leads to cancer cell death. percent through 2027.

FDA 94

FDA Vaccines Immunization Compounding 94

Pharmaceutical Technology

JUNE 27, 2022

Turning Point Therapeutics has entered a strategic research and development alliance with the University of Texas MD Anderson Cancer Center (MD Anderson) to advance the evaluation of two of its investigational small molecules for precision cancer treatments. A kinase inhibitor, elzovantinib (TPX-0022) targets MET, CSF1R and SRC.

Chemotherapy 59

Chemotherapy Compounding 59

PharmaShots

APRIL 7, 2023

TG Therapeutics Receives EMA’s CHMP Positive Opinion of Briumvi (ublituximab-xiiy) for the Treatment of Relapsing Forms of Multiple Sclerosis Date: Apr 3, 2023 | Tags: TG Therapeutics, Briumvi, Ublituximab-xiiy, Multiple Sclerosis, Regulatory, EMA, CHMP BMS Receives EMA’s CHMP Positive Opinion of Breyanzi (lisocabtagene maraleucel) for (..)

FDA 53

FDA Immunization 53

PharmaShots

JUNE 9, 2023

Quell Therapeutics Signed an Exclusive Option and License Agreement with AstraZeneca to Develop, Manufacture and Commercialize Engineered Treg Cell Therapies Date: June 09, 2023 | Tags: Quell Therapeutics, AstraZeneca, Engineered Treg Cell Therapies, Type 1 Diabetes, Inflammatory Bowel Disease, Biotech, Treg cell engineering modules Astellas and the (..)

FDA 40

FDA 40

Pharmaceutical Technology

APRIL 24, 2023

As healthcare confronts challenges such as antimicrobial resistance and the spread of previously geographically constrained diseases as a result of climate change, research into natural products used in traditional medicine, referred to as ‘ethnopharmacology’, could help in finding new, clinically effective drugs.

Compounding 105

Compounding Chemotherapy 105

Pharmaceutical Technology

MAY 31, 2023

Fruquintinib is under clinical development by Takeda Pharmaceutical and currently in Phase II for Triple-Negative Breast Cancer (TNBC). According to GlobalData, Phase II drugs for Triple-Negative Breast Cancer (TNBC) have a 24% phase transition success rate (PTSR) indication benchmark for progressing into Phase III.

Pharmaceutical Companies 40

Pharmaceutical Companies Pharmaceutical Companies Vaccines 40

STAT

JULY 24, 2023

Further testing over the next couple of weeks clarified the cause: Gosline had stage 4 colorectal cancer, which had spread to his liver. That’s “the very hard question that none of us really know the answer to,” said Timothy Rebbeck, professor of cancer prevention at the Harvard T.H. Chan School Of Public Health.

Medical Schools 98

Medical Schools Hospitals Chemotherapy Immunization 98

The Checkup by Singlecare

OCTOBER 16, 2023

Cancers This disability category includes all cancers except cancer linked to HIV. These conditions primarily include certain cancers and adult brain disorders,” says Casey Walker , an occupational therapist at Tilton’s Therapy in Nevada. A full list of CAL conditions can be found on the Social Security website.

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Documentation Immunization Mayo Clinic Insurance 105

pharmaphorum

APRIL 26, 2022

Ben Hargreaves speaks to companies that are developing therapies not just in gastrointestinal conditions but also in broader areas, such an immuno-oncology. The gut microbiome has long been linked to gastrointestinal conditions, such as inflammatory bowel disease and irritable bowel diseases, as well as obesity and type 2 diabetes.

Immunization 114

Immunization FDA 114

pharmaphorum

APRIL 14, 2021

Boehringer Ingelheim and The University of Texas MD Anderson Cancer Center have extended and expanded a collaboration exploring medicines targeting lung cancer with KRAS mutations. . KRAS is the most frequently mutated gene that causes cancer and is expressed in one in seven of all human metastatic cancers.

FDA 52

FDA 52

The Checkup by Singlecare

AUGUST 24, 2023

the clinical pharmacy program director at Harbor Health. Many probiotic supplements include acidophilus and other beneficial bacteria strains, says Amy Lee, MD , RDN, chief medical officer at Lindora Clinic in California. It] also may improve the progression of cervical cancer.”

Immunization 98

Immunization Pharmacy Program Director Dosage Chemotherapy 98

pharmaphorum

JUNE 23, 2022

BRAF V600E mutations are seen in around 20 different types of cancer, said Novartis, which has previously won regulatory approvals for the combination as treatment for BRAF-mutated melanoma, non-small cell lung cancer (NSCLC) and thyroid cancers. billion to Novartis’ top-line last year. Tabrecta approved in Europe.

FDA 52

FDA Chemotherapy 52

The Checkup by Singlecare

JANUARY 26, 2024

Diverticulitis is the most common cause of pain specific to the lower left abdomen, says Amy Lee , MD, RDN, chief medical officer at Lindora Clinic. Ovarian cyst : A non-cancerous sac on the ovary that could also cause bloating and pelvic pressure. What causes lower abdominal pain on the left side?

Mayo Clinic 52

Mayo Clinic Immunization Hospitals 52

Board Vitals - Pharmacist

FEBRUARY 9, 2024

The Radiology Qualifying (Core) Exam is designed to evaluate a candidate’s core fund of knowledge and clinical judgment across practice domains of diagnostic radiology and integrated interventional radiology/diagnostic radiology.

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52

Pharmaceutical Technology

APRIL 12, 2023

The latest move is a result of the cancellation of a licensing agreement between Cancer Prevention Pharmaceuticals (CPP) and One-Two Therapeutics Assets. It is expected to focus on FAP patients with intact lower gastrointestinal anatomy. The new registration trial will be based on positive data obtained from the FAP-310 trial.

FDA 52

FDA 52

The Checkup by Singlecare

FEBRUARY 1, 2024

The GCR is a physiological reflex that increases the motility of the lower gastrointestinal tract (colon) in response to a meal,” says Caroline Soyka, DO , a board-certified gastroenterologist with Gastro Health of Jupiter, Florida. Why do I have to poop right after I eat?

Chemotherapy 52

Chemotherapy 52

pharmaphorum

MAY 4, 2022

The FDA has kicked off a priority review of AstraZeneca’s checkpoint inhibitor Imfinzi for biliary tract cancer (BTC), setting up what could be approval for an immunotherapy for the group of rare and aggressive gastrointestinal tumours. The post AZ eyes Q3 FDA decision for Imfinzi in biliary tract cancer appeared first on.

FDA 52

FDA Chemotherapy 52

pharmaphorum

MAY 14, 2021

BMS is setting up Zeposia as a first or second line therapy and noted clinical evidence that the drug reduces relapses and brain lesions compared with Biogen’s Avonex (interferon beta-1a). But NICE said in its guidance that the drug’s impact on disability progression was unclear from the clinical evidence presented by BMS’ Celgene unit.

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The Checkup by Singlecare

DECEMBER 29, 2023

Over time, persistent heartburn can lead to gastroesophageal reflux disease (GERD)—a chronic form of heartburn—esophageal damage, or cancer. Heartburn that is frequent or interferes with your day-to-day life may indicate a more serious gastrointestinal condition requiring medical treatment. Alcohol is a common heartburn trigger.

Mayo Clinic 105

Mayo Clinic Compounding 105

The Checkup by Singlecare

NOVEMBER 13, 2023

Therefore, the pain can be a symptom of an issue with the lungs, abdomen, musculoskeletal system, reproductive system, gastrointestinal system, or urinary system. Lung cancer Studies show that 20%–40% of people with lung cancer have chest pain. Both are responsible for chronic inflammation of the gastrointestinal tract.

Mayo Clinic 52

Mayo Clinic Vaccines Chemotherapy Communication 52

Pharmaceutical Technology

FEBRUARY 19, 2023

Camrelizumab is under clinical development by Jiangsu Hengrui Medicine and currently in Phase I for Solid Tumor. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

Chemotherapy 40

Chemotherapy 40

pharmaphorum

DECEMBER 10, 2020

Boehringer Ingelheim has expanded its oncology focus for the second time this week by buying Swiss biotech NBE-Therapeutics, adding an antibody-drug conjugate (ADC) platform led by a drug for a hard-to-treat form of breast cancer. The post Boehringer buys NBE for €1.18bn, adding cancer ADC expertise appeared first on.

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Vaccines Immunization FDA 58