Remove brain-barriers-research-center
article thumbnail

First implantable pump kills brain cancer using chemo

European Pharmaceutical Review

A Phase I study published in the Lancet Oncology , demonstrated the first implantable pump system for patients with brain cancer , effectively killed recurrent glioblastoma (GBM) tumour cells by bypassing the blood-brain barrier to continuously deliver chemotherapy through a tube inserted directly into the brain.

article thumbnail

At ESMO, three studies show promise of antibody-drug conjugates in breast cancer

pharmaphorum

The American Society of Clinical Oncology, or ASCO, conference is just around the corner, but one subgroup of cancer researchers just had their own gathering, as breast cancer researchers came together in person for the first time since the start of the pandemic at the ESMO Breast Cancer congress.

Insiders

Sign Up for our Newsletter

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Trending Sources

article thumbnail

Why Is Nobody Using Your Guidelines? – Insights On Designing Useful Guidelines For Infectious Diseases

IDStewardship

Additionally, the Centers for Medicaid & Medicare Service (CMS) Center for Clinical Standards and Quality/Quality, Safety & Oversight Group released updates to interpretive guidance for hospital requirements, making their antimicrobial stewardship regulations live now. These barriers can be difficult to address.

Hospitals 130
article thumbnail

FDA approves over-the-counter naloxone

The Checkup by Singlecare

“Naloxone is a critical tool in addressing opioid overdoses, and today’s approval underscores the extensive efforts the agency has undertaken to combat the overdose crisis,” said Patrizia Cavazzoni, MD, director of the FDA’s Center for Drug Evaluation and Research, in a statement released Mar.

FDA 98
article thumbnail

Delivery systems for biologics

European Pharmaceutical Review

Barriers that complicate biologics delivery include their susceptibility to enzyme degradation, serum protein interactions, electrostatic repulsion, neutralising immune reaction, and intracellular shielding like endosomal escape, among others. Dave Li, PhD Dave Li is a principal consultant and Clinical Research Physician with KCR.

FDA 93
article thumbnail

How to counsel patients with sleep issues

The Checkup by Singlecare

The Centers for Disease Control and Prevention (CDC) defines insomnia as the inability to initiate or maintain sleep—in other words, difficulty falling asleep or staying asleep. Second-generation antihistamines, such as loratadine, block histamine receptors but do not cross the blood-brain barrier.

Dosage 52
article thumbnail

Strategies to Overcome Anxiety with Hashimoto’s

The Thyroid Pharmacist

There are many well-documented side effects of antidepressants and benzodiazepines, ranging from the rare but serious – suicidal ideation/action, homicidal ideation/action, and even death – to the very common – brain fog , weight gain , sexual dysfunction , and feeling disconnected from reality. [2]