Pharmaceutical Technology

JANUARY 12, 2023

It has been approved to treat NSCLC patients with EGFR Exon20 insertion mutations, whose disease has advanced on or after they received platinum-based chemotherapy. Rash, decreased appetite, paronychia, and diarrhoea are the most common adverse reactions (TRAEs) related to the treatment.

Adverse Reactions

PharmaShots

JUNE 6, 2023

Shots: The P-III study (TROPiCS-02) evaluating Trodelvy vs CT in a ratio (1:1) in 543 patients with HR+/HER2- metastatic breast cancer who progressed on endocrine-based therapies and 2 chemotherapies In the exploratory analysis, improvement in m-OS benefit (14.5 vs 11.2mos.), PFS rates at 6/12/18mos. vs 29.4%)/ (21.7% vs 8.4%)/ (14.4%

Adverse Reactions

The Checkup by Singlecare

APRIL 14, 2024

Certain supplements, flea medications, and chemotherapy drugs may also cause adverse reactions. Metronidazole also has drug interactions with several other medications, including cyclosporine, phenobarbital, and phenytoin. How much metronidazole can I give my dog?

Dosage

The Checkup by Singlecare

JUNE 20, 2023

If your immune system is compromised due to medication, chemotherapy, or radiation therapy, probiotics may increase the risk of developing a bacterial or fungal infection. People with compromised immune systems. People with a severe illness. Together, you can weigh the benefits and risks carefully. The post Who should not take probiotics?

Immunization

pharmaphorum

JANUARY 26, 2022

It covers three phase 3 trials involving subjects with myelodysplastic syndrome (MDS) and acute myeloid leukaemia (AML), as well as ‘unfit’ AML patients who are unable to be treated with intensive treatment like high-dose chemotherapy.

FDA

The Checkup by Singlecare

JANUARY 23, 2024

It is known as an antineoplastic (chemotherapy) agent, a disease-modifying antirheumatic drug ( DMARD ), and an immunosuppressant agent. Methotrexate has distinct mechanisms of action for its use as chemotherapy versus immunosuppression in autoimmune diseases.

Adverse Reactions

European Pharmaceutical Review

DECEMBER 27, 2023

Bridging therapy has been shown to correlate with an inferior response to CAR T-cell therapy due to both progression of the chemotherapy-refractory malignant disease during the manufacturing period and increased toxicity. After this incident CAR-related toxicity scales and guidelines were established to prevent adverse reactions.

Adverse Reactions

The Checkup by Singlecare

OCTOBER 16, 2023

Chemotherapy-Induced Peripheral Neuropathy Studies have shown that duloxetine may help prevent or reduce nerve pain in people who have been treated with chemotherapy. For example, you may have experienced adverse reactions or other health concerns while taking the generic version in the past.

Dosage

The Checkup by Singlecare

OCTOBER 27, 2023

By bringing up a potential interaction with amoxicillin-potassium clavulanate, you could avoid an adverse reaction or, at the very least, have peace of mind and a better understanding of why it is being prescribed for you. Taking an active role in your own care is essential for the best outcomes.

Adverse Reactions

The Checkup by Singlecare

DECEMBER 29, 2022

Nonimmunologic reactions. Nonimmunologic reactions are reactions that don’t involve the immune system and are not typically considered true allergic reactions. Instead, these non-allergic adverse reactions may be caused by the drug itself or unknown reasons. Most common culprits of reactions.

Adverse Reactions

Pharmaceutical Technology

JANUARY 13, 2023

Enhertu has been approved to treat HER2-low breast cancer adult patients who have previously received at least one line of chemotherapy in the metastatic setting or who have seen disease recurrence during or within six months after the adjuvant chemotherapy. Enhertu’s safety profile was consistent with the previous clinical trials.

Chemotherapy

Pharmaceutical Technology

FEBRUARY 5, 2023

The FDA approval is based on the data obtained from a global, multicentre, open-label Phase III TROPiCS-02 study conducted in 543 HR+/HER2- metastatic breast cancer patients who have received prior endocrine therapy, CDK4/6 inhibitor and two to four lines of chemotherapy for metastatic disease. Trodelvy showed 3.2

FDA

Pharmaceutical Technology

MARCH 23, 2023

Zynyz monotherapy showed a 52% objective response rate (ORR) in chemotherapy-naïve patients. Diarrhoea, rash, pyrexia, nausea, musculoskeletal pain, fatigue and pruritus are the most common adverse reactions observed in patients treated with Zynyz. Partial response was seen in 22 patients and complete response in 12 patients.

FDA

European Pharmaceutical Review

NOVEMBER 24, 2022

s Libtayo ® (cemiplimab) for adults with recurrent or metastatic cervical cancer and disease progression while on or after platinum-based chemotherapy. “Libtayo ® was the first programmed cell death protein (PD)-1 inhibitor to demonstrate significant improvements in survival compared to chemotherapy in a Phase III trial.

Chemotherapy

Pharmaceutical Technology

NOVEMBER 23, 2022

Libtayo is also indicated for treating progression of the disease on or following platinum-based chemotherapy. The trial enrolled 608 subjects in 14 countries, regardless of their PD-L1 expression status or histology and assessed Libtayo versus a chemotherapy of investigator's choice.

Adverse Reactions

pharmaphorum

OCTOBER 19, 2020

The FDA’s approval covers use of Venclexta (venetoclax) in combination with azacytidine, or decitabine, or low-dose cytarabine (LDAC) for newly diagnosed AML in adults 75 years or older, or who have comorbidities preventing intensive induction chemotherapy. months compared with 4.1 months for those treated with LDAC alone.

Adverse Reactions

pharmaphorum

APRIL 1, 2021

The FDA has approved Sanofi’s Sarclisa (isatuximab) in combination with a new chemotherapy regimen for advanced multiple myeloma, building on a first approval last year. The median progression free survival (PFS) for Sarclisa combination therapy was not reached at the time of the pre-planned interim analysis, the company said.

Adverse Reactions

Hospital Pharmacy Europe

DECEMBER 14, 2023

Dostarlimab (brand name Jemperli) has been granted marketing authorisation by the European Commission (EC) in combination with carboplatin-paclitaxel (chemotherapy) for certain types of endometrial cancer, its manufacturer GSK has announced.

Chemotherapy

The Thyroid Pharmacist

SEPTEMBER 1, 2023

They include anesthetics, antacids, anti-anxiety medications, antibiotics, antidepressants, antifungals, cholesterol-lowering medications, anti-malarial medications, chemotherapy, appetite suppressants, arthritis medications, psychotropics, and steroids. Who is Likely to Have an Adverse Reaction to Fluoride, and What are the Symptoms?

Adverse Reactions

The Thyroid Pharmacist

JULY 8, 2022

It’s important to note that selenium may also interact with other supplements and medications, such as cholesterol-lowering statin drugs, antacids, chemotherapy drugs, corticosteroids, niacin, and even birth control pills. At high enough levels, selenium can cause death (reports of this level of toxicity exist, but are extremely rare). (58,

Dosage

The Checkup by Singlecare

FEBRUARY 1, 2024

Prednisone is usually used as an add-on treatment to chemotherapy drugs or as a palliative treatment for advanced cancers. Of the lymphatic cancers, lymphoma is common, representing about 15% to 20% of cancers diagnosed in dogs every year. Lymphatic cancer cells have corticosteroid receptors that induce those cells to die.

Dosage