Remove 2023 Remove Adverse Reactions Remove Chemotherapy
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How AI Brings Pharmacogenetics to the Frontline of Precision Medicine

Pharmacy Times

A man aged 55 years with metastatic colorectal cancer was initiated on a standard fluoropyrimidine-based chemotherapy regimen. Early identification of genetic markers associated with treatment efficacy or adverse reactions helps reduce late-stage clinical trial failures and improves the overall efficiency of the development pipeline.

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Gilead to Presents P-III (TROPiCS-02) Study Results of Trodelvy (sacituzumab govitecan) for Pre-Treated HR+/HER2- Metastatic Breast Cancer at ASCO 2023

PharmaShots

Shots: The P-III study (TROPiCS-02) evaluating Trodelvy vs CT in a ratio (1:1) in 543 patients with HR+/HER2- metastatic breast cancer who progressed on endocrine-based therapies and 2 chemotherapies In the exploratory analysis, improvement in m-OS benefit (14.5 vs 11.2mos.), PFS rates at 6/12/18mos. vs 29.4%)/ (21.7% vs 8.4%)/ (14.4%

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Developing point-of-care CAR T manufacturing

European Pharmaceutical Review

Bridging therapy has been shown to correlate with an inferior response to CAR T-cell therapy due to both progression of the chemotherapy-refractory malignant disease during the manufacturing period and increased toxicity. After this incident CAR-related toxicity scales and guidelines were established to prevent adverse reactions.

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Methotrexate interactions to avoid

The Checkup by Singlecare

It is known as an antineoplastic (chemotherapy) agent, a disease-modifying antirheumatic drug ( DMARD ), and an immunosuppressant agent. Methotrexate has distinct mechanisms of action for its use as chemotherapy versus immunosuppression in autoimmune diseases.

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Amoxicillin-potassium clavulanate interactions to avoid

The Checkup by Singlecare

By bringing up a potential interaction with amoxicillin-potassium clavulanate, you could avoid an adverse reaction or, at the very least, have peace of mind and a better understanding of why it is being prescribed for you. Taking an active role in your own care is essential for the best outcomes.

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Fluoride And Your Thyroid

The Thyroid Pharmacist

They include anesthetics, antacids, anti-anxiety medications, antibiotics, antidepressants, antifungals, cholesterol-lowering medications, anti-malarial medications, chemotherapy, appetite suppressants, arthritis medications, psychotropics, and steroids. Who is Likely to Have an Adverse Reaction to Fluoride, and What are the Symptoms?