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The MEK effect on cancer — a slow and steady approach to drug resistance

PharmaVoice

You just want to slash it, rip it out or attack it like an enemy target,” said Benjamin Zeskind, co-founder, CEO and president of Immuneering Corporation. To overcome that hurdle, Immuneering is testing an approach that slows cancer down rather than rushing to destroy it.

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Lumateperone Submits Application for Schizophrenia Indication to FDA for Supplemental New Drug

Pharmacy Times

Factors associated with relapse in schizophrenia despite adherence to long-acting injectable antipsychotic therapy. International Clinical Psychopharmacology, 31 (4), 202–209. Lafeuille, M. Lefebvre, P., Fastenau, J., Doshi, D., & & Duh, M. Journal of Medical Economics, 16 (11), 1290–1299.

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Steroid Use During ICI Treatment Lessens Effectiveness in Patients With NSCLC

Pharmacy Times

SHOW MORE Steroids hindered the shrinkage of tumors in patients with non-small cell lung cancer (NSCLC) receiving immune checkpoint inhibitor (ICI) therapy. A total of 277 patients (median age: 66 years; range: 30–89 years) with NSCLC who initiated treatment between October 2013 and August 2023 were enrolled. months) and 6.4

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Unicorns Don’t Exist: Rethinking the Generalist Model in Oncology Pharmacy

Pharmacy Times

Touchstone Books; 2013. Time Enough for Love. Putnam’s Sons; 1973. Hyperbole and a Half: Unfortunate Situations, Flawed Coping Mechanisms, Mayhem, and Other Things That Happened. Rao KV, Gulbis AM, Mahmoudjafari Z. 2022;5(11):1112-1120. doi:10.1002/jac5.1693 4. 6 challenges facing community oncology practices.

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IBI303, Humira Biosimilar, Shows Comparable Efficacy and Cost Benefit to Reference Product

Pharmacy Times

1 In 2013, Humira was approved in China as a treatment for ankylosing spondylitis, a chronic inflammatory disease that causes axial arthritis and often results in inflammatory lower back pain early in the disease’s course.

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Managing Tardive Dyskinesia With VMAT2 Inhibitors in Clinical Practice

Pharmacy Times

Cambridge University Press; 2013:129-236. Psychiatry Clin Neurosci. 2015;69(6):321-334. doi:10.1111/pcn.12270 12270 Stahl SM. Antipsychotic agents. In: Stahl’s Essential Psychopharmacology: Neuroscientific Basis and Practical Applications. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders.

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Estrogen Dominance as a Trigger for Hashimoto’s

The Thyroid Pharmacist

In a 2013 randomized controlled trial of women with hot flashes, those who took a progesterone medication saw an increase in thyroid hormone levels. Beyond the estrogen-thyroid connection, there is an immune connection as well. The reason for this may be the effect of hormones on the immune system.