pharmaphorum

AUGUST 25, 2022

Tecvayli (teclistamab) has been approved by the European Commission for adults with the blood cancer whose disease has progressed have after at least three prior therapies, including an immunomodulatory agent, a proteasome inhibitor, and an anti-CD38 antibody, said J&J.

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FDA Immunization 98

European Pharmaceutical Review

JUNE 8, 2023

Methods of the microbial biosurfactant study The first stage of the downstream method combined TAG selective removal from glycolipids. The post Novel nanofiltration method for microbial biosurfactant downstream processing appeared first on European Pharmaceutical Review. Overall, Nascimento et al. The paper was published in Membranes.

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Pharmaceutical Technology

JULY 14, 2022

Despite this high number, orphan diseases are rare by definition, affecting around one in 2,000 people as defined by the European Union. Due to the high price tags associated with these speciality medicines, innovators have naturally favoured big markets with high GDP such as the US and EU-5 (Germany, France, Spain, Italy, and the UK). “The

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Pharmaceutical Companies Pharmaceutical Companies Hospitals 59

pharmaphorum

JANUARY 18, 2022

The hope is that they will harness and re-programme natural cellular mechanisms to selectively remove the disease driving proteins from human tissues, working by boosting interactions – gluing – between therapeutically relevant proteins and the machinery used by cells to naturally tag and destroy proteins.

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Immunization 52

European Pharmaceutical Review

MARCH 1, 2023

The authors explained that these are commonly used for tagging proteins for study or attaching protein drugs to drug-delivering nanoparticles. To create the surface required, the team coated gold nanoparticles with bioconjugates maleimide (MAL) and N -hydroxysuccinimide ester (NHS).

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Vaccines 92

pharmaphorum

NOVEMBER 19, 2020

Because Roche has never applied for Avastin to be used in wet AMD, clinics in the US have had to choose between the peace of mind offered by the regulatory process and Lucentis’ higher price tag, or the unapproved off-label formulation of Avastin at a lower price.

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FDA Labelling 64

pharmaphorum

APRIL 14, 2022

million price tag. bluebird pulled it off the market last year however and retreated from the European market, saying the pricing and reimbursement environment was too hostile to make its business there viable. The gene therapy has already been approved for marketing in the EU and UK, where it was launched at a cost of around $1.7

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FDA 64

pharmaphorum

JANUARY 21, 2022

Access to medicines is “one of the most challenging policy areas in every country in the European region” – it’s time to develop a solution that works for everyone. In recent years, revolutionary medicines have come with price tags to match, but this is simply a symptom of our current model.

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Insurance Vaccines 52

pharmaphorum

JUNE 2, 2022

This is why the action by the US in 1983 and subsequently the European Commission Regulation No. While in 2021, orphan drugs made up over half of all the US FDA’s approvals, with the figures in European being similarly high – 19 out of 54 approved new active substances. It is estimated that between 3.5 Raising questions.

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Compounding Pharmaceutical Companies Pharmaceutical Companies 52

European Pharmaceutical Review

AUGUST 24, 2022

tag ® , inspired by the unique features of microtubule biology and perfectly suited for DAR 2 and DAR 4 ADCs. European Journal of Organic Chemistry. The post Actualising the power of antibody-drug conjugates as cancer therapeutics appeared first on European Pharmaceutical Review. New England Journal of Medicine. and Antibody?Drug?Conjugates.

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Compounding Pharmaceutical Companies Pharmaceutical Companies 80

Pharmaceutical Technology

MARCH 22, 2023

The pharmaceutical industry began using radio frequency identification (RFID) tags in the early 2000s. Pfizer was the first to use the tech, adding RFID tags to track a Viagra (sildenafil) shipment circa 2006. Twenty years ago, the cost of implementing RFID tags and the ecosystem (software) was much more expensive than today.

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Labelling Data Entry Communication FDA 105

pharmaphorum

NOVEMBER 16, 2022

Only a few years later, bluebird bio’s gene therapy, Zynteglo (betibeglogene autotemcel), was approved in the European market for the treatment of the rare blood disorder, beta thalassaemia. However, with a price tag of €1.58 How to navigate the new climate. At more than $2.1

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pharmaphorum

DECEMBER 2, 2020

In 1919 their scientists pioneered mould fermentation production of citric acid from molasses, freeing their citric acid business from European citrus fruit supplies, which had been disrupted by the First World War. For all the latest Pfizer news follow pharmaphorum’s Pfizer tag. The post A history of Pfizer appeared first on.

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Compounding Vaccines Pharmaceutical Companies Pharmaceutical Companies 128

Pharmaceutical Technology

JUNE 21, 2023

The high price tag may be hard to defend , but with lifetime treatment costs for haemophilia B reaching as high as $23m for some, the single-dose treatment could prove far more cost-effective. Despite the limited market, the price tags of haemophilia make it potentially lucrative. Haemophilia B is a rare condition.

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FDA 98

PharmaShots

MARCH 9, 2023

Other Affiliations: Angela is an active Board of Director member of the Pfizer Foundation (a charitable organization addressing global health challenges), European Federation of Pharmaceutical Industries and Associations (EFPIA), and UPS (the global leader in package delivery and supply chain logistics). LinkedIn Total experience: 16 yrs.

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FDA Pharmaceutical Companies Pharmaceutical Companies Immunization 40

pharmaphorum

AUGUST 26, 2022

The US biotech claimed conditional marketing approval from the European Commission for Roctavian (valoctocogene roxaparvovec) as a treatment for adults with severe haemophilia A, who don’t have a history of developing the antibodies that inhibit the activity of blood-clotting protein Factor VIII. million spread over five years.

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FDA 111

European Pharmaceutical Review

MAY 11, 2023

1 This is assuming a $1M price tag for all gene therapies. Catherine Eckford is Editorial Assistant at European Pharmaceutical Review. Available from: [link] The post Realising milestones with gene therapy for SMA appeared first on European Pharmaceutical Review. What are the emerging modalities in the gene therapy sector?

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FDA 68

European Pharmaceutical Review

JULY 11, 2022

These coronavirus RBDs are attached to a nanoparticle by protein tags, enabling the structure to display fragments from multiple viruses on a single nanoparticle. . The post CEPI provides $30m to advance novel coronavirus vaccine appeared first on European Pharmaceutical Review. The innovative protein ?“glue”

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Vaccines Immunization 91

European Pharmaceutical Review

NOVEMBER 10, 2022

BT-474 cell line was gene-edited to incorporate a green fluorescent protein (GFP) tag into late endosomes/lysosomes (green). The post Putting complex medicines under the microscope appeared first on European Pharmaceutical Review. Physical characterisation. Journal of Extracellular Vesicles, 10, e12130.

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Labelling Compounding 94

European Pharmaceutical Review

DECEMBER 27, 2023

This data has been captured by CAR T-cell registries that were established first by the Center for International Blood and Marrow Transplant Research (CIBMTR) and later by the European Society for Blood and Marrow Transplantation (EBMT). This is in addition to its considerable price tag. Annals of Oncology. 2022;33(3):259–75.

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Adverse Reactions Immunization Medical Schools Chemotherapy 81

Policy Prescription

APRIL 1, 2022

I know of no other counterfeit drug breach in Canada or the European Union of this magnitude. . Instead, if those Americans who purchased fake HIV drugs at their local Walgreens or CVS had ordered from a pharmacy in Canada or the European Union, then they would have gotten the right product at a lower price. Fake DSCSA Pedigrees.

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FDA Documentation 40