Pharmaceutical Technology

MARCH 23, 2023

The deal, expected to be completed by the end of 2023, will see Pfizer pay $229 per Seagen share in cash for a total of $43bn, the largest deal for the sector in the past three years. The drug is also approved for other CD30-expressing T-cell lymphomas, such as anaplastic large cell lymphoma, in both frontline and refractory settings.

Chemotherapy 59

Chemotherapy Compounding FDA 59

pharmaphorum

DECEMBER 15, 2020

Over the past year, we have witnessed first-hand how older, “less innovative” molecules have been integral for emergency treatment in hospitals, and also how they have been central to clinical trial research in identifying existing medicines that can be used to treat COVID-19. “Now Ensuring healthcare sustainability.

Generic Medicine 72

Generic Medicine Pharmaceutical Companies Pharmaceutical Companies Vaccines 72

pharmaphorum

JANUARY 11, 2023

AI chatbots use real-world examples – the text of hundreds of millions of web pages […] Of course, for every real-world problem that has large, available data sets, there are dozens of others that have only limited training data.”. On the computer, we design billions of novel drug-like molecules that have never been made before.

Compounding 121

Compounding 121

pharmaphorum

AUGUST 27, 2020

However, companies in the sector have tended to stall prior to achieving scale. Regulatory pressures, lengthy drug development times, and the fact that drug prices have become politicised have raised risks and cut revenue projections, leading to the biotech sector falling out of fashion. Two key trends underpin the sector’s resurgence.

Vaccines 111

Vaccines Compounding Pharmaceutical Companies Pharmaceutical Companies 111

Pharmaceutical Technology

SEPTEMBER 14, 2022

Pharmaceutical Technology has listed the leading API biologics (protein and peptide) companies in contract marketing based on its intel, insights, and decades-long experience in the sector. The advancement in drug design has led to the development of new drug molecules in the form of API peptides and proteins.

Documentation 52

Documentation 52

Pharmaceutical Technology

SEPTEMBER 8, 2022

Pharmaceutical Technology has listed the top solid dose manufacturing companies and solid dose pharmaceutical companies based on our intel, insights and decades-long expertise in the sector. Growth of oral solid dosage contract manufacturing in the pharmaceutical industry.

Dosage 40

Dosage Packaging Documentation Pharmaceutical Companies 40

pharmaphorum

MAY 12, 2022

The platform – called BRASS (Benefit-Risk Analytic System) – was developed by Boehringer to unlock hidden patient safety signals from large data sets, and will be layered into ArisGlobal’s LifeSphere safety and pharmacovigilance platform. ” The post Boehringer sells drug safety software to ArisGlobal appeared first on.

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Adverse Reactions Pharmaceutical Companies Pharmaceutical Companies 52

Pharmaceutical Technology

SEPTEMBER 15, 2022

Pharmaceutical Technology has listed the leading commercial dose injectables companies in contract marketing based on its intel, insights, and decades of experience in the sector. Discover the top commercial dose injectables companies in contract marketing.

Documentation 52

Documentation Pharmaceutical Companies Pharmaceutical Companies Communication 52

Impact Pharmaceutical Services

FEBRUARY 1, 2022

Based in Boston, MA, Syner-G is a leading provider of customized science and risk-based CMC and regulatory solutions and services, supporting pharmaceutical and biotechnology companies across small molecule, large molecule, and cell and gene therapy products. For more information, visit www.impactpharma.com. 508) 460-9700.

Customer Service 40

Customer Service 40

pharmaphorum

OCTOBER 6, 2021

Digital health tools hold huge potential, and the evidence base is growing all the time – so what is holding us back and how does the sector overcome the multiple barriers to widespread adoption? One of the challenges pharma has is that it cannot be truly patient-centric because it starts with the molecule,” he said.

Hospitals 98

Hospitals 98

IDStewardship

JUNE 5, 2023

This can help researchers identify novel targets, repurpose existing drugs, and design new molecules with enhanced antimicrobial activity, potentially overcoming resistance mechanisms. AI algorithms can analyze large-scale genomics, imaging, and clinical data to identify potential biomarkers, therapeutic targets, or patient subgroups.

Vaccines 234

Vaccines Hospitals Patient Care 234

pharmaphorum

JULY 4, 2022

T1D Moonshot aims to change that by bringing knowledgeable partners together from various sectors of the healthcare community to explore innovative ways to prevent and treat T1D. “Michael Mason is leading a $12 billion a year franchise for Lilly, from molecules to devices. Still, a scarcity of T1D treatments exists.

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European Pharmaceutical Review

NOVEMBER 4, 2022

One of the many hurdles to improving these therapies, the taxane molecules themselves exhibit poor water solubility and vulnerability to inactivation by various internal biologic processes, 2 significantly limiting chances of success. Potential of oral taxanes and initial outcomes in the clinic. About the author.

Chemotherapy 83

Chemotherapy FDA Hospitals Packaging 83

pharmaphorum

DECEMBER 2, 2020

This expertise in fermentation and large-scale pharmaceutical production put Pfizer in good stead when in 1941 the US government appealed to the pharma industry for support in producing penicillin for the war effort. At the time $160 billion deal was the biggest ever seen in the pharma sector. No signs of slowing down.

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Compounding Vaccines Pharmaceutical Companies Pharmaceutical Companies 128

European Pharmaceutical Review

JUNE 27, 2023

This followed results from a large metagenomics study published in November 2022, in which gut microbiome was identified as a key part of Parkinson’s pathogenesis. In January 2022, Hervé was elected President of Allliance Promotion Microbiote, an organisation founded in 2021 to support the microbiome sector development in France.

Chemotherapy 99

Chemotherapy Immunization FDA Vaccines 99

pharmaphorum

NOVEMBER 15, 2022

That said, Zemp and Lydon concluded that there is still excitement about what the sector has to offer. Primarily, it can be an uphill battle to convince investors that a smaller organisation can do something significant with an asset that a large pharma company has deprioritised. For Müllenbeck, this is an opportunity.

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European Pharmaceutical Review

JULY 14, 2023

At 68 percent, the small molecules sector currently holds the largest share in the overall market. However, extensive capital investment and complex infrastructure is necessary for carrying out in-house filling of biologics and small molecules, which can be a challenge for drug developers with limited finances and capacity constraints.

Packaging 88

Packaging Compounding 88

Pharmaceutical Technology

JULY 25, 2022

Few players currently manufacture specialty generics, but these expensive drugs can be a significant contributor to the growth of the entire generics sector. In the specialty generics sector, there are fewer competitors and it is slower for new companies to enter the same space, says Frank. But there are some exceptions.

FDA 119

FDA Medical Schools Dosage 119

European Pharmaceutical Review

DECEMBER 21, 2022

All traditional small molecule pharmaceuticals include carbon building blocks” Organic compounds are arguably the foundation of the pharmaceutical industry. Large-scale manufacturing of defossilised chemicals like methanol could create a segue for a CCU industry and represent a first milestone.

Compounding 76

Compounding Pharmaceutical Companies Pharmaceutical Companies Packaging 76

Pharmaceutical Technology

AUGUST 26, 2008

. “The inherent advantages of biopharma are that it allows you to pursue therapies against targets that are not small molecule therapies, for example by targeting protein-protein interactions and targeting GPCRs (G-protein coupled receptors),” he says. “Biotechnology has exploded across the industry. .”

Pharmaceutical Companies 52

Pharmaceutical Companies Pharmaceutical Companies Vaccines Immunization 52

European Pharmaceutical Review

JANUARY 16, 2023

Tim Sandle: The adoption of EU GMP Annex 1 is occupying a lot of time across the pharmaceutical sector and various projects will stem from that in relation to contamination control. This also occupies a large resource, given the US Food and Drug Administration (FDA) requirement for double plate checking using a second ‘independent’ person.

Vaccines 127

Vaccines FDA Research Laboratories Documentation 127

European Pharmaceutical Review

SEPTEMBER 16, 2022

Since the developed regions of the world started to get COVID-19 under control, focus on this matter has only grown – particularly in the pharmaceutical sector, which played a critical role in curbing the devastation caused by the pandemic. But how will this drive for resilience shape the future of pharmaceutical supply chains?

Packaging 88

Packaging Documentation 88

European Pharmaceutical Review

OCTOBER 12, 2023

While the data was based on responses from 292 manufacturers across all sectors, the outcomes are applicable to pharmaceutical manufacturing. Output in the manufacturing sector weakened over the past quarter and is expected to flatline at best through the rest of this year.

Vaccines 86

Vaccines Dosage Pharmaceutical Companies Pharmaceutical Companies 86

European Pharmaceutical Review

NOVEMBER 10, 2022

A new wave of medicines has emerged in recent years to supplement the well-established small and large molecule platforms that have historically dominated the market. While there is a significant market opportunity in this sector, advanced analytical methods are required, and many technologies cannot provide the resolution needed.

Labelling 97

Labelling Compounding 97

European Pharmaceutical Review

APRIL 30, 2024

The eventual goal is to have a pilot/large scale model which can meet rapid deployment pandemic needs. For example, they will continue to mainly focus on one lead candidate, instead of working on multiple molecules in their pipeline. I see the market picking back up towards the end of 2024 or early 2025.

Vaccines 80

Vaccines FDA 80

pharmaphorum

APRIL 19, 2021

If you look over the last 20 years it has gone from 10-12 major players with large R&D down to two. If you get a small molecule version of something that works the likelihood is it will spread into mild and moderate disease. “It It broadens the utility of the molecule and we expect it to be trialled in more moderate diseases.”.

Vaccines 93

Vaccines 93

PharmaShots

FEBRUARY 20, 2023

To overcome the requirement of large investment, running costs, poor scalability, risk of batch loss by contamination, and whose production is not possible by chemical synthesis, one common practice in the life science industry is molecular farming.

Vaccines 40

Vaccines Pharmaceutical Companies Pharmaceutical Companies Compounding 40

Pharmaceutical Technology

SEPTEMBER 8, 2022

Pharmaceutical Technology has listed some of the top API biologics companies in contract marketing based on our intel, insights and decades-long experience in the sector. Biologics development is a complex and expensive process.

Vaccines 40

Vaccines Packaging Documentation Labelling 40

ISPE

NOVEMBER 10, 2022

As cell manufacturing is a live continuous process, it requires a different approach from conventional chemical compounds and small molecules manufacturing. Manual effort also has the associated high costs for setting up HVAC for the large grade B space required, which increases the investment for companies getting started.

Documentation 98

Documentation Compounding Hospitals Immunization 98

Pharmaceutical Technology

OCTOBER 27, 2022

These capabilities include cell and gene therapies, which China would like to develop to move away from its current focus on high-volume, low-value (often generic) API small molecule manufacture. respectively (28 and 26 notices) across all sectors. Chinese investors often face increased scrutiny when attempting to invest in the US.

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Pharmaceutical Technology

JUNE 14, 2023

A GlobalData report which analyzes trends in new drug approvals [i] shows that small molecule approvals have now been surpassed (in 2022) by biologics. Small molecules only accounted for 41% of NME (New Molecular Entity) approvals in 2022.

Packaging 52

Packaging Labelling 52

PharmaShots

MAY 1, 2023

Shots: In the wake of International Labour Day, PharmaShots presents a detailed take on the recent layoffs in the Pharmaceutical Sector with an illustrative graphical analysis Like any sector, the pharmaceutical industry operates on some nuance and intricate aspects that ensure smooth operations.

Pharmaceutical Companies 40

Pharmaceutical Companies Pharmaceutical Companies Vaccines 40

PharmaShots

MAY 1, 2023

Shots: In the wake of International Labour Day, PharmaShots presents a detailed take on the recent layoffs in the Pharmaceutical Sector with an illustrative graphical analysis Like any sector, the pharmaceutical industry operates on some nuance and intricate aspects that ensure smooth operations.

Pharmaceutical Companies 40

Pharmaceutical Companies Pharmaceutical Companies Vaccines 40

European Pharmaceutical Review

FEBRUARY 23, 2023

This article presents an overview of Raman spectroscopy and details some of the developments of interest to the pharmaceutical sector. Raman spectroscopy Raman spectroscopy is a spectroscopic technique based on the vibrational modes of molecules. Certain spectral regions will be relevant for bacterial fingerprinting.

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Labelling Packaging 105

pharmaphorum

MAY 21, 2021

Arecor Therapeutics is the latest company aiming to take advantage of the “feelgood” factor in the biotech sector, which has seen huge investment ever since the pandemic began last year. It’s Arecor’s hope that one of these could catch the eye of one of the large companies working in metabolic and cardiovascular diseases.

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Viseven

SEPTEMBER 14, 2023

The pharma sector now reconsiders its procurement process for improved efficiency, resilience, and cost optimization. Implementing innovative technologies Cutting-edge drugs, such as stem cell therapy or large molecule biologics, require innovative transportation methods to keep the damage risks close to zero.

Packaging 52

Packaging Pharmaceutical Companies Pharmaceutical Companies Pharmacy Procurement 52

pharmaphorum

SEPTEMBER 13, 2022

During this period, Nobel prize-winning German scientist Paul Ehrlich developed his lock-key hypothesis of molecules that specifically bind to cell receptors. Johnson & Johnson’s Darzalex (daratumumab) was a notable development for the sector. However, effective treatments were not available at the time.

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Chemotherapy Immunization FDA Documentation 94