Pharmaceutical Technology

MAY 1, 2023

The California Institute of Regenerative Medicine (CIRM) has awarded $3.46m Clinical Stage Research Programme (CLIN1) grant to Ossium Health for advancing OSSM-007 development to treat steroid-refractory acute graft versus host disease (GVHD). OSSM-007 is the interferon-gamma primed mesenchymal stem cell product of Ossium Health.

FDA 64

FDA 64

pharmaphorum

JUNE 3, 2021

There is also some preliminary data from South Africa which indicates that beta might be associated with higher in-hospital mortality, so it is one of the prime targets for governments looking to procure additional doses of vaccine for booster campaigns. 1.351 – which is estimated to be around 50% more transmissible than earlier strains.

Vaccines 111

Vaccines Immunization Hospitals 111

pharmaphorum

JUNE 9, 2022

The London-based start-up has been founded by David Baker, head of the Institute of Protein Design at the University of Washington in Seattle, and Laksh Aithani, whose past roles include a couple of years working on the machine learning platform of fellow UK-based AI specialist Exscientia. .

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pharmaphorum

SEPTEMBER 1, 2020

The US trial is funded by the US government agency Biomedical Advanced Development Authority (BARDA), and the National Institute of Allergy and Infectious Diseases, which as part of the National Institutes of Health is funded by federal grants. Feature image courtesy of Rocky Mountain Laboratories/NIH.

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Vaccines Immunization 69

pharmaphorum

AUGUST 16, 2021

It was formed in 2019 as the result of a partnership between UK drug research institute The Beckley Foundation and Canopy Growth Corporation. Beckley – formerly known as Beckley Canopy Therapeutics – raised £7.4 million in 2018 to develop a range of cannabis-based products for the treatment of pain and to help tackle opioid addiction.

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Compounding 135

pharmaphorum

JUNE 30, 2021

ILAP is a key part of the UK’s post-Brexit regulatory framework for new medicines, working in a similar way to the EU’s Priority Medicines (PRIME) pathway that also provides a fast-track route to regulatory approval for therapies that promise to deliver a big benefit to patients.

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FDA 98

European Pharmaceutical Review

MAY 17, 2023

This suggested that the immune system may be primed to respond to anti-PD-1 immunotherapy. The study enrolled 49 patients with recurrent GBM from several institutions between September 2016 to January 2019.

Immunization 86

Immunization Chemotherapy 86

pharmaphorum

SEPTEMBER 14, 2020

After vaccination, the surface spike protein is produced, priming the immune system to attack the SARS-CoV-2 virus if it later infects the body. China’s CanSino, Russia’s Gamaleya Research Institute and Janssen are also near the top of the list, along with US biotech Moderna.

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Vaccines Immunization 102

pharmaphorum

SEPTEMBER 11, 2022

With the results in hand, the developers of the therapy – from the Netherlands Cancer Institute and Norway’s National Center for Cancer Immune Therapy – say they now intend to file for regulatory approvals in Europe before the end of the year, without a commercial partner “to try to ensure that it remains affordable.”

Chemotherapy 104

Chemotherapy Immunization Hospitals 104

Pharmaceutical Technology

JUNE 8, 2023

Furthermore, Gritstone’s samRNA increased and potentially broadened functional Spike-specific T cell responses and primed T cell responses to conserved non-Spike epitopes. According to GlobalData , there are over 800 Covid-19 vaccines in the pipeline, 42.6% of these are in the pre-clinical stage.

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Vaccines Immunization Communication 52

pharmaphorum

FEBRUARY 19, 2021

This week UK prime minister Boris Johnson is to pledge at a G7 summit that the country will donate surplus doses from its vaccination campaign to poorer countries. The vaccine doses will be manufactured and distributed globally by Novavax and Serum Institute of India (SII), the latter under an existing agreement between Gavi and SII.

Vaccines 77

Vaccines 77

The Checkup by Singlecare

DECEMBER 26, 2023

“Because the causes of black tarry stools are indicative of upper gastrointestinal bleeding, they will not tend to cause low back pain,” says David Bilstrom, MD , owner of Autoimmune Functional Medicine and director of the International Autoimmune Institute & Bingham Memorial Center for Functional Medicine in Blackfoot, Idaho.

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pharmaphorum

FEBRUARY 2, 2021

This pharmaphorum webinar, held in association with the National Institute for Health Research (NIHR), will take place on Thursday 25 th March at 15:30 GMT / 16:30 CET and look at where virtual trials fit into the next generation of pharmaceutical clinical research.

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pharmaphorum

OCTOBER 18, 2022

Leading institutional investors include Earlybird and Novartis Venture Fund, with funds managed by Tekla Capital Management LLC and VI Partners, among others. The combination of Oculis SA and EBAC is estimated to have a post-transaction enterprise value of around $220 million, with a cash balance over $200 million.

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The Checkup by Singlecare

MARCH 21, 2024

Even if a BCBS plan does offer coverage for Wegovy, patients have to meet specific criteria.

Insurance 52

Insurance Insurance Coverage Labelling 52

Pharmaceutical Technology

JULY 28, 2022

Thanks to a highly skilled talent pool, world-class lab infrastructure and renowned research institutions, the US has cemented its position as a proven market for life sciences. Linked to talent, the presence of good universities is another great sign for life sciences, especially institutions with a focus on healthcare.

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Research Laboratories Patient Care 52

Pharmaceutical Technology

JULY 7, 2022

So, what will Boris Johnson, a UK Prime Minister defenestrated by his own MPs, be most remembered for? His refusal to resign in the face of a mass revolt of his own ministers expanded the moral vacuum at his core to encompass and suffocate the institutions of state. Boris was bad for business. A country diminished.

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pharmaphorum

NOVEMBER 16, 2020

During his tenure the EMA also implemented new rules to encourage the development of advanced therapy medicinal products (ATMPs) like gene and cell therapies, and the introduction of the PRIME fast-track review for promising medicines. Emer Cooke. I am leaving EMA at a time when its mandate is set to be expanded.

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Vaccines Packaging FDA 62

STAT

DECEMBER 18, 2023

The closely watched gene-editing startup Prime Medicine is embroiled in a multimillion-dollar dispute with another biotech it partnered with to develop a potentially powerful new form of genome editing.

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Fuld

APRIL 24, 2022

Until now, financial institutions offered only traditional services, such as banking activities and trading facilities. Like cotton candy stalls at a carnival, FinTech payment companies are prime targets for cybercriminals. India’s UPI is also among the prime examples of a highly accessible tech-mediated financial ecosystem.

Grocery Stores 52

Grocery Stores Insurance 52

STAT

JULY 24, 2023

And quadruple the risk of getting rectal cancer,” said Dr. Kimmie Ng, director of the Young-Onset Colorectal Cancer Center at the Dana-Farber Cancer Institute. According to National Cancer Institute  data , pancreatic cancer among men younger than 50 increased 6.5 percent from 2000 to 2019.

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Medical Schools Hospitals Chemotherapy Immunization 98

Pharmaceutical Technology

NOVEMBER 4, 2022

A prime example is the Precision Medicine Scotland Innovation Centre (PMS-IC) in Glasgow, which is a consortium of NHS partners across the country and associated universities, bringing together a range of different companies and health experts in a dedicated precision medicine ecosystem.

Chemotherapy 52

Chemotherapy Documentation 52

The Checkup by Singlecare

DECEMBER 29, 2022

As we get older, it’s harder to keep our mind as sharp as it once was in our prime. Alzheimer’s disease fact sheet , National Institute on Aging. National Institute on Aging. Risk factors and warning signs of Alzheimer’s , National Institutes of Health. Age-related forgetfulness is a normal experience.

Assisted Living 52

Assisted Living FDA 52

The Checkup by Singlecare

DECEMBER 7, 2023

Sources Insomnia: Definition, prevalence, etiology, and consequences , Journal of Clinical Sleep Medicine (2019) Key sleep disorders , CDC (2022) What is insomnia?

Dosage 52

Dosage FDA Labelling 52

pharmaphorum

NOVEMBER 10, 2022

Elliott informed those in attendance that for the next five years, with about £5 billion in funding for pipelines across a network of research and institute centres in clinical trials, that the aim is for everyone to live a life free of cancer. The key, she said, is working in partnership.

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Vaccines Pharmaceutical Companies Pharmaceutical Companies Labelling 97

IDStewardship

AUGUST 29, 2022

Make sure to check your local institution’s internal policy to see if there are certain indications where an infectious disease specialist consultation is required. Hospital discharge is also a prime time for reviewing the patients’ prescribed antimicrobial therapies. This also increases their hospital readmission rates post-discharge.

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Hospitals Dosage Documentation Compounding 130

pharmaphorum

OCTOBER 5, 2022

An effective vaccine would be transformative in the fight against the Neisseria gonorrhoeae pathogen that causes the disease, but efforts to date have been unsuccessful as many structures on the bacterial envelope can rapidly change, which makes it hard to single out an antigen that can be used to prime the immune system.

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Vaccines Immunization 98

ISPE

JUNE 8, 2023

Biopharmaceutical companies and research institutions need a new paradigm for designing, building, and operating facilities that can power their innovations and bring them to market swiftly and efficiently. This often leaves those organizations with only two options: either retrofit an existing space or build a new one.

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European Pharmaceutical Review

MAY 11, 2023

3 The one-time gene therapy received final draft guidance from the National Institute for Health and Care Excellence (NICE) on 16 March 2023. Rare, genetic diseases like SMA are prime targets for gene therapy, but by their very nature, early signs can be difficult to recognise, delaying diagnosis and treatment. Why is it significant?

FDA 74

FDA 74

PharmaShots

JUNE 1, 2023

PDC*line is much more potent than conventional dendritic cell-based vaccines in priming and boosting antitumor antigen-specific cytotoxic T-cells, including the T-cells specific for neoantigens, and is synergistic with checkpoint inhibitors. The technology can potentially be applied to any type of cancer.

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Immunization Vaccines Health and Personal Care Stores Labelling 40

pharmaphorum

NOVEMBER 13, 2020

Hungary’s prime minister Viktor Orban has warned that the country’s health service could be overwhelmed if the infection rate is not brought under control. Minister of foreign affairs and trade Peter Szijjarto has been in talks with Russia, China and Israel in order to obtain early supplies of a vaccine.

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Vaccines 113

pharmaphorum

FEBRUARY 2, 2021

“The vaccine is 100% effective in preventing serious disease or death, which in the end is the most crucial parameter; we can all deal with the sniffles as long as we stay out of the hospital or the graveyard,” said Hildegund Ertl of the Wistar Institute in Philadelphia, US.

Vaccines 76

Vaccines Documentation Labelling Hospitals 76

European Pharmaceutical Review

JUNE 28, 2022

In a natural infection, activation of naïve T-cells by dendritic cells will occur before systemic inflammation occurs – ie, priming occurs before physical symptoms. T-prime vaccines can generate blood-circulating CD8+ T-cells that have the clonal imprinting to enable them to become tissue-resident memory T-cells.

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Vaccines Immunization Medical Schools Compounding 95

The Checkup by Singlecare

MARCH 21, 2024

“Obesity is truly a disease that is associated with many health conditions such as diabetes, heart disease, high blood pressure, and sleep apnea,” says Michelle Pearlman, MD , CEO and co-founder of Prime Institute and ByteMD, who is board certified in internal medicine, gastroenterology, and obesity medicine.

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Insurance Insurance Coverage FDA 98

The Digital Apothecary

APRIL 26, 2019

After all, the $1 Billion PillPack acquisition by Amazon and their recent outreach to Prime members has caused quite the hubbub in the health sector. Many already grumble in institutional settings where they are in the hospital basement. After all, most pharmacists got into this career to help people.

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Communication Packaging Patient Care Hospitals 52

European Pharmaceutical Review

MAY 9, 2023

Both Pfizer and Moderna use RNA technology that delivers genetic code to cells that prime the immune system to recognise and attack the coronavirus. Participants who received the Moderna COVID vaccine had a response 51 times higher than those given the Johnson & Johnson vaccine.

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Vaccines FDA Immunization 91

European Pharmaceutical Review

DECEMBER 18, 2023

This includes the National Institute for Health and Care Excellence (NICE)’s recommendation of the first treatment for Parkinson’s disease, Produodopa (foslevodopa–foscarbidopa). At the beginning of this year, EPR reported on the potential blockbuster pharmaceutical drugs to watch in 2023.

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Hospitals FDA 97