ChatGPT Provides Inaccurate Responses to Questions About Drug Information
Drug Topics
DECEMBER 7, 2023
Two posters presented at ASHP 2023 Midyear examined how accurate answers were from the artificial intelligence chatbot.
Sat.Dec 02, 2023 - Fri.Dec 08, 2023
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Addressing Burnout: Why Psychological Safety Matters at Work
Pharmacy Times
DECEMBER 8, 2023
Psychological safety substantially contributes to team effectiveness, learning, employee retention, and—most critically—better decisions and better performance.
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In historic decision, FDA approves a CRISPR-based medicine for treatment of sickle cell disease
STAT
DECEMBER 8, 2023
The Food and Drug Administration on Friday approved the world’s first medicine based on CRISPR gene-editing technology, a groundbreaking treatment for sickle cell disease that delivers a potential cure for people born with the chronic and life-shortening blood disorder. The new medicine , called Casgevy, is made by Vertex Pharmaceuticals and CRISPR Therapeutics.
Generative AI expected to take off in 2024, but concerns linger over cost, reliability and security
Fierce Healthcare
DECEMBER 6, 2023
Only 25% of healthcare organizations have deployed generative AI solutions. | Only 25% of healthcare organizations have deployed generative AI solutions but that is expected to more than double next year as executives see opportunities to automate clinical documentation and improve patient communication.
Position Your Pharmacy for Expansion
Speaker: Chris Antypas and Josh Halladay
Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.
Pharmacists Play Unique Role in Advancing Health Equity for Patients With Chronic Disease
Drug Topics
DECEMBER 7, 2023
A new study, outlined in a poster at ASHP Midyear 2023, identified 3 key themes associated with the ways in which pharmacists are positioned to advance health equity for patients with chronic diseases.
Migraine Medication Could Be More Effective Than Ibuprofen for Treatment of Attacks
Pharmacy Times
DECEMBER 4, 2023
Three classes of drugs could be 2 to 5 times more effective than ibuprofen for the treatment of migraine attacks, according to results of a study.
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Pharmacy Technician Pulse brings together the best content for pharmacy technicians from the widest variety of industry thought leaders.
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FDA approves bluebird's sickle cell disease gene therapy. Can Lyfgenia overcome CRISPR’s halo?
Fierce Pharma
DECEMBER 8, 2023
Alongside a historic approval for the first therapy utilizing the Nobel Prize-winning CRISPR/Cas9 gene-editing technology, the FDA has cleared a rival gene replacement therapy, also for sickle cell | Alongside a historic approval for the first therapy utilizing the Nobel Prize-winning CRISPR/Cas9 gene-editing technology, the FDA has cleared a rival gene replacement therapy, also for sickle cell disease (SCD).
Instagram Could Serve as Educational Platform for New FDA Drug Approvals
Drug Topics
DECEMBER 4, 2023
An evaluative study on an open resource Instagram page that provides information on new medications to pharmacists was recently presented at the American Society of Health-System Pharmacists 2023 Midyear Clinical Meeting and Exhibition.
FDA Approves Isavuconazonium Sulfate to Treat Invasive Aspergillosis and Invasive Mucormycotic
Pharmacy Times
DECEMBER 8, 2023
The approval marks isavuconazonium sulfate as the only granted azole antifungal therapy for pediatric individuals AI and IM that are as young as 1 years old.
Mexico’s activist ‘companion networks’ quietly provide abortion pills and support to U.S. women
STAT
DECEMBER 7, 2023
TIJUANA, Mexico — Just over a decade ago, when Crystal Pérez Lira needed an abortion, she had to leave Mexico. The procedure was illegal in her home state of Baja California and so deeply stigmatized that even Pérez Lira supported the procedure only for those who were raped. Until she unexpectedly got pregnant. She traveled to the U.S. for help, walking alone across the border from Tijuana to San Diego, first for a health check and a compulsory ultrasound, and then back for a se
What the FDA's New Dosage Guidance Means for the Future of Clinical Research
Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist
What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.
UnitedHealth report: Chronic conditions like depression, diabetes are on the rise
Fierce Healthcare
DECEMBER 6, 2023
Chronic conditions, including mental health needs, are on the rise, according to a new report. | The United Health Foundation, the philanthropic arm of industry giant UnitedHealth Group, released its annual America's Health Rankings report.
The Unintended Impact of Opioid Prescribing Guidelines: Part 1
Drug Topics
DECEMBER 5, 2023
The CDC first released opioid prescribing guidelines in 2016.
The Future of Immunotherapy in Breast Cancer Involves Engineered T-Cell Therapies, Better Prediction of Adverse Effects
Pharmacy Times
DECEMBER 8, 2023
As the use of sequencing, proteomics, and immunopeptidomics increases, more targets will also be discovered, as well as more biomarkers that predict responses to treatments.
New gene therapies confront many sickle cell patients with an impossible choice: a cure or fertility
STAT
DECEMBER 6, 2023
As a teenager, Marie Tornyenu was always having to explain herself. If it wasn’t the chronic absences that had her doing homework from a hospital bed, it was the quilted blanket she carried with her on the days she could attend class. “It was a running joke that I was like 80 years old,” she said. “I would usually just laugh it off because the alternative was too depressing.
5 Reasons to Upgrade Your Pharmacy Management Software
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Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.
A tough 2024 is on the horizon. Here's how Deloitte says healthcare leaders should prepare
Fierce Healthcare
DECEMBER 6, 2023
Many of the past year’s buzziest topics and omnipresent struggles will likely rear their heads as major talking points across 2024, per the year-ahead predictions of Deloitte’s healthcare industry | Generative AI, outsourcing and skilled labor retention are among the focal points provider and payer executives will need to keep in their crosshairs.
Novartis hit with FDA letter detailing 'significant' Kymriah manufacturing shortfalls
Fierce Pharma
DECEMBER 7, 2023
When it comes to manufacturing cell therapies, it's often said that the "process is the product." But churning out these complex, individualized drugs has routinely tripped up even the industry's l | In recent months, Novartis has faced scrutiny from the FDA over Kymriah production shortfalls, a newly posted letter shows. The company says it's working to address the situation.
Reduced Structural Stigma Against Sexual Minorities Is Associated With Greater Rates of Male PrEP Prescriptions
Pharmacy Times
DECEMBER 4, 2023
The study authors note that additional policies to reduce structural stigma against sexual minorities could continue to improve the rate of individuals who initiate PrEP use.
‘Last roll of the dice’ for a near-term HIV vaccine fails
STAT
DECEMBER 6, 2023
A study billed as the last chance to develop an HIV vaccine this decade has been shut down, investigators announced Wednesday at a conference in Harare, Zimbabwe. The trial, known as PrEPVacc, was testing two different vaccine regimens on about 1,500 volunteers in East and Southern Africa. After multiple other high-profile trials failed , a PrEPVacc investigator described the study this summer as “ the last roll of the dice ” for an HIV vaccine until the 2030s.
Tough labor market holds Fitch's nonprofit hospital outlook at 'deteriorating'
Fierce Healthcare
DECEMBER 5, 2023
Nonprofit hospitals will continue to operate under a cloud of labor supply shortages and “pressured” margins into 2024, setting the coming 12 months up as another “make or break year” for the secto | Fitch Ratings' pessimistic 2024 outlook highlighted labor shortages, an uptick in union activity and potential second year of debt service covenant violations.
Vertex, CRISPR score landmark FDA approval for sickle cell disease gene therapy Casgevy
Fierce Pharma
DECEMBER 8, 2023
Groundbreaking? Game-changing? Transformational? Historic? | Vertex Pharmaceuticals and CRISPR Therapeutics have won an historic FDA approval for their sickle cell disease gene therapy Casgevy. The transformational treatment is a potential cure for the debilitating and life-threatening disease which affects more than 100,000 in the United States, most of them Black.
Study Results Demonstrate Neurodevelopment Comparable Between CHEU, CHUU at 1 Year
Pharmacy Times
DECEMBER 7, 2023
The study authors note that addressing environmental factors, such as IPV and food insecurity, can provide further benefits in neurodevelopment regardless of maternal HIV status.
New England Journal of Medicine reckons with its racist past and complicity in slavery
STAT
DECEMBER 6, 2023
The New England Journal of Medicine, the world’s oldest continually published medical journal, publicly reckoned with its history and complicity surrounding slavery and racism Wednesday, publishing the first of a series of essays by independent historians on the role the prestigious publication has played in perpetuating racist thinking in medicine that continues to this day.
Hims & Hers rolls out weight loss program with future plans to include GLP-1 drugs
Fierce Healthcare
DECEMBER 6, 2023
Digital health company Hims & Hers launched its much-anticipated weight loss program this week that includes digital tracking tools, educational content and access to medications. | Digital health company Hims & Hers launched its much-anticipated weight loss program this week that includes digital tracking tools, educational content and access to medications.
Bristol Myers Squibb bids farewell to dealmaking czar Elizabeth Mily
Fierce Pharma
DECEMBER 8, 2023
Three years on, Bristol Myers Squibb is bidding adieu to its top dealmaker. | Three years on, Bristol Myers Squibb is bidding adieu to its top dealmaker. Elizabeth Mily, who replaced BMS’ former M&A czar Paul Biondi back in 2020, is headed for the exit, the company confirmed Friday.
FDA Approves Casgevy, Lyfgenia for the Treatment of Sickle Cell Disease
Pharmacy Times
DECEMBER 8, 2023
This FDA approval represents the first cell-based gene therapies for the treatment of sickle cell disease in patients 12 years of age and older.
STAT+: CVS’s new drug payment plan won’t lower patients’ prices, experts warn
STAT
DECEMBER 5, 2023
CVS Health is promising to simplify how its pharmacies get paid for drugs. But that doesn’t mean the drugs will get cheaper. The country’s biggest pharmacy chain said it’s switching to a system where pharmacy benefit managers, employers, and other insurers pay for drugs based on the cost of the drug plus a set markup and dispensing fee.
White House, senators take aim at 'corporate greed in healthcare'
Fierce Healthcare
DECEMBER 7, 2023
Both the executive branch and key bipartisan legislators announced plans Thursday to tackle the negative impacts of corporate interests and ownership in healthcare. | Multiple federal agencies and bipartisan Senate leaders have launched a salvo of efforts targeting anticompetitive behaviors, high prices and private equity-involvement in the healthcare industry.
As Stelara cliff looms, J&J expects 25 blockbuster drugs to drive future sales growth
Fierce Pharma
DECEMBER 5, 2023
As Johnson & Johnson places a magnifying glass on its pharmaceutical business, the focus for the remainder of the decade rests on the shoulders of some 25 new and upcoming drugs.
FDA Approves Iptacopan for the Treatment of Paroxysmal Nocturnal Hemoglobinuria in Adult Patients
Pharmacy Times
DECEMBER 6, 2023
During clinical trials, individuals treated with iptacopan had increased hemoglobin levels and did not need to receive blood transfusions.
STAT+: J&J to emphasize cancer drugs and stop much of its vaccine research
STAT
DECEMBER 5, 2023
Eight months into his tenure, Johnson & Johnson’s R&D chief is putting a big emphasis on medicines for cancer, treatment-resistant depression, and autoimmune disease. To sharpen that focus, R&D chief John Reed told STAT that the company is de-emphasizing two areas that have been mainstays for the drug and medical device giant: infectious disease and vaccines, as well as medicines targeting kidney disease and rare eye conditions.
Cardiovascular disease is a major concern for women. Here's what employers can do
Fierce Healthcare
DECEMBER 6, 2023
Cardiovascular disease is a key health concern for women, and a new guide seeks to arm employers with the tools and information need | Cardiovascular disease is a key health concern for women, and a new guide seeks to arm employers with the tools and information needed to help workers manage these needs.
FDA endorses Novartis' 'pipeline in a pill,' granting first nod for potential blockbuster Fabhalta
Fierce Pharma
DECEMBER 6, 2023
With an FDA approval in PNH, Novartis has gained its first nod for iptacopan, dubbed two months ago “a pipeline in pill," by analysts at ODDO BHF.
Study Finds Inavolisib Combination Treatment Improved PFS in Patients With Breast Cancer
Pharmacy Times
DECEMBER 5, 2023
In the first-line setting, inavolisib plus palbociclib and fulvestrant improved PFS in patients with HR-positive breast cancers; however, further research is needed to understand the trends in OS.
Is the flu shot market a slam dunk for mRNA vaccines? Experts aren’t so sure
STAT
DECEMBER 5, 2023
Here are two things that are true. The world needs more effective flu vaccines. And pharmaceutical companies that learned of the vaccine-making power of the messenger RNA platform during the Covid-19 pandemic need new markets for their technology.
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