Sat.Mar 09, 2024 - Fri.Mar 15, 2024

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Assessing the Current and Future Landscape of Pharmacy

Drug Topics

A panel discussion at the Outcomes 2024 SYNC National Conference touched upon many important themes in community pharmacy, including the evolving role of pharmacists, emerging tech, and key challenges going forward.

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A Pharmacist’s Guide to Continuous Glucose Monitoring

Pharmacy Times

This guide discusses the integration of continuous glucose monitoring (CGM) technology into clinical practice, emphasizing the role of pharmacists in selecting and optimizing CGM devices for patients.

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Why gut bacteria is the next frontier in medicine

pharmaphorum

Discover why gut bacteria are considered the next frontier in medicine in this informative article. Learn about the importance of the microbiome, its impact on health, and how it relates to conditions like Clostridiales difficile.

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“Food Is Medicine” Movement Takes Off

Pharmacy Times

Integrate nutrition into the health care system with a proactive approach to chronic disease management

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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How Daylight Saving Time Increases Overall Health Risks

Drug Topics

Recent studies on daylight saving time’s association with increased health risks have heightened the debate on whether to observe the biannual event or switch to one universal time.

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With Pfizer struggling in 2023, CEO Bourla hit with 35% pay cut to $21.6M

Fierce Pharma

Pfizer knew 2023 was going to be a challenging year of transition. But even the drugmaker was surprised by the plummeting demand for its COVID-19 products, missing badly on its 2023 guidance. | After a difficult year for Pfizer, in which its share price fell by 44%, CEO Albert Bourla’s compensation fell by 35% from $33 million in 2022 to $21.6 million in 2023.

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Elranatamab Maintains or Improves Symptoms and Health Status of Patients With Multiple Myeloma

Pharmacy Times

This finding was evident in both examined groups and regardless of the patients' B-cell maturation antigen-directed therapy status.

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Blood-Based Test Demonstrates High Sensitivity for Colorectal Cancer

Drug Topics

A blood-based cell-free DNA (cfDNA) test was able to find patients at increased risk of colorectal cancer (CRC), advanced neoplasia, and advanced precancerous lesions.

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HIMSS24: Oracle Health builds out generative AI tools in its quest to 'eliminate clicks' for clinicians

Fierce Healthcare

ORLANDO, Florida — Software giant Oracle continues to build out generative AI tools in its healthcare solutions as it debuted a new service for care management this week and plans to roll out | Oracle is integrating generative AI and ambient listening technologies into its EHR to streamline medical notetaking for clinicians. "We're not trying to go from 10 clicks to seven clicks.

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STAT+: Medicare couldn’t cover Wegovy for weight loss. But now that it’s also a heart drug, the door is open

STAT

WASHINGTON — Novo Nordisk’s newly won permission to market the heart benefits of its obesity drug Wegovy could provide a backdoor way to expand access to the drug for people on Medicare, experts told STAT. Currently, Medicare is prohibited by law from covering medications for obesity treatment alone. While companies that manufacture wildly popular anti-obesity medications and their allies haven’t been successful in lobbying Congress to change the law , the Food and Drug

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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Pharmacy Focus: Limited Series: Celebrity Endorsements in Ozempic

Pharmacy Times

This podcast episode discussed the impact of celebrity endorsements on trends in weight loss drugs like Ozempic, body image issues, and the role of pharmacists in educating patients on appropriate use of GLP-1 medications for weight management and chronic diseases.

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CDC Says US Will Transition to Trivalent Vaccines Next Flu Season

Drug Topics

Since changes in vaccine composition can sometimes lead to confusion or misinformation, effective communication is crucial to promote vaccine uptake.

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HIMSS24: 'Fasten your seatbelts'—Hackensack Meridian CEO predicts acceleration of gen AI to help healthcare workforce

Fierce Healthcare

ORLANDO — It's almost impossible to have a conversation at HIMSS24 without the topic of artificial intelligence or generative AI coming up. | How will the conversations about AI in healthcare change by next year's HIMSS conference? Hackensack Meridian CEO Robert Garrett predicts that pilot projects underway now will roll out into practice.

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Opinion: No parent who has seen the children I’ve treated for measles would refuse a vaccine

STAT

Over the past year, I have watched many children die of measles. In the final stages, little lungs, filled with fluid and racked with inflammation, struggle for oxygen. The victims breathe faster and faster, gasping for air until, exhausted, they stop.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Study: Only 40% of Adults With Childhood Asthma Experience Remission

Pharmacy Times

The study showed no clinical differences for remission or asthma at age 28 years based on lung function, body mass index, daily smoking, exposure to parental tobacco smoke, or house dampness.

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Psilocybin Analog for Treatment of Depression Receives FDA Breakthrough Therapy Designation

Drug Topics

Cybin’s proprietary deuterated psilocybin analog, CYB003, provided robust and sustained improvements in depression symptoms in a phase 2 study.

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AHA: 94% of hospitals financially impacted by Change Healthcare's cyberattack

Fierce Healthcare

Nearly every hospital is feeling the consequences of Change Healthcare’s cyberattack on their finances, patient care delivery, or both, according to reports from almost 1,000 hospitals compiled by | Almost 60% of surveyed hospitals reported at least $1 million of impacted revenues per day, and 74% said that the incident has had "direct" implications on patient care within their facilities.

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Rigid rules at methadone clinics are jeopardizing patients’ path to recovery from opioid addiction

STAT

DETROIT — Every morning, Rebecca Smith, nursing a surgically repaired knee, carefully walks down the hallway of her brutalist brick apartment building, takes the elevator one floor to the lobby, and negotiates the sharply angled driveway outside. There, she waits for an Uber to take her to the last place she wants to go: her methadone clinic.

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FDA Approves sBLA to Extend Temperature Storage Conditions for Two IVIG Products

Pharmacy Times

The IVIG therapies were previously approved for 4-week room temperature storage conditions of 25º Celsius during the first 24 months of shelf life.

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FDA approves first MASH drug: Madrigal's Rezdiffra breaks ground in notorious biopharma graveyard

Fierce Pharma

The decades-long wait for an effective treatment for metabolic dysfunction-associated steatohepatitis (MASH) has ended, as the FDA has approved the first drug for the fatty liver disease. | The decades-long wait for an effective treatment for metabolic dysfunction-associated steatohepatitis (MASH) has ended. The FDA has approved Madrigal's resmetirom under the brand name Rezdiffra as the first drug for the fatty liver disease.

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HIMSS24: How Epic is building out AI, ambient technology for clinicians

Fierce Healthcare

ORLANDO — A year ago, at HIMSS23 in Las Vegas, Epic announced it was working with Microsoft to integrate large language model tools and AI into its electronic health record software. | AI technology in healthcare is rapidly evolving, and the potential for generative AI to free up time to focus more on patients is getting clinicians excited about technology, said Jacqueline Gerhart, M.D., Epic clinician and vice president of clinical informatics.

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STAT+: UnitedHealth is on a buying spree of outpatient surgery centers

STAT

UnitedHealth Group quietly acquired dozens of outpatient facilities in 2023, with a particular focus on surgery centers, according to a STAT review of company financial filings. Those acquisitions — nearly all of which the company never announced — build on the network of some 90,000 physicians UnitedHealth Group has amassed in recent years.

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FDA Approves Maralixibat for Treatment of Pediatric Patients With PFIC

Pharmacy Times

The drug is indicated for patients 5 years of age and older with progressive familial intrahepatic cholestasis and cholestatic pruritus in pediatric patients with Alagille syndrome.

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Biotech trade group pledges support for BIOSECURE Act, plans to boot member WuXi AppTec

Fierce Pharma

As CDMO giants Wuxi AppTec and WuXi Biologics come under mounting scrutiny for their alleged ties to Chinese government officials, they are losing a key ally in Washington, D.C. | As CDMO giants Wuxi AppTec and WuXi Biologics come under mounting scrutiny for their alleged ties to Chinese government officials, they are losing a key ally in Washington, D.C.

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HIMSS24: Google Cloud builds out generative AI solutions to aid healthcare workers

Fierce Healthcare

ORLANDO — Generative AI continues to be a big buzzword in 2024 as tech companies see the potential to use the technology to alleviate administrative drudgery for healthcare workers. | Google Cloud is using its tech muscle to build out generative AI capabilities for healthcare and life sciences companies to help offload administrative burden and support assistive technology for clinicians.

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STAT+: Hemophilia gene therapies arrived after 40 years of struggle. Where are the patients?

STAT

As a boy growing up with hemophilia A, Noah Frederick reserved the end of his annual checkups to talk about new technologies. His doctor walked through various experimental approaches for the bleeding disorder and, invariably, gene therapy. It was coming, he always said, in your lifetime. Last year, it finally arrived. But Frederick, now a 23-year-old software engineer, isn’t sure he’ll get it.

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Navigating Research in Psychedelics: Investigators Face a Mosaic of Regulations, False Perceptions, and Therapeutic Potential

Pharmacy Times

If clinical trials continue to show that psychedelics offer safe and long-lasting results, then psychedelic-assisted therapy could flourish as a treatment in the mental health space.

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When £17m isn’t enough: FTSE firms plead to pay bosses millions more

The Guardian - Pharmaceutical Industry

Confronted by the huge salaries on offer in the US, London boardrooms are lobbying to be allowed to make their own bosses even wealthier There was a sharp intake of breath last month when the pharmaceuticals group AstraZeneca cemented chief executive Pascal Soriot’s position as the best-paid FTSE 100 boss with a £17m pay package , up from £15.3m a year earlier.

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MedPAC report slammed by insurers and docs over Medicare Advantage and physician reimbursement

Fierce Healthcare

Health plans and providers alike are disgruntled with a new report (PDF) to Congress released | It seems everyone was left unsatisfied by MedPAC's newest report to Congress. Providers objected to its proposal to give physician reimbursement relief, while plans disagreed with its attitude toward Medicare Advantage.

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Opinion: Disabled scientists are often left out of academia. The NIH can help change that

STAT

Despite being the largest minority in the nation , disabled people like us have been structurally and institutionally obstructed from entering research-dominated fields. When they do manage to break through, they are seldom given the support and accommodations needed to sustain employment and thrive in their professional lives. As we have experienced, including people with disabilities in academic leadership and decision-making positions can lead to innovation, creative problem-solving, and insi

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GZ17-6.02 Effective in Killing Multiple Myeloma Cells, Other Benefits When Combined With Bortezomib

Pharmacy Times

The combination of GZ17-6.02 and bortezomib reduced of HDAC, and as a result ATG13 phosphorylation was enhanced, BAK levels increased, and BCL-XL levels were reduced.

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Despite early death concerns, FDA advisers back J&J and Legend's Carvykti for earlier myeloma

Fierce Pharma

Even though the BCMA CAR-T therapy Carvykti showed a potential problem of early patient deaths in a trial, experts on the FDA’s Oncologic Drugs Advisory Committee (ODAC) still believe that the drug | Even though the BCMA CAR-T therapy Carvykti showed a potential problem of early patient deaths in a trial, experts on the FDA’s Oncologic Drugs Advisory Committee still believe that the drug’s long-term benefits outweigh its risks.

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New Mayo Clinic program to qualify, integrate digital health offerings into clinical care

Fierce Healthcare

Mayo Clinic wants to help digital health more quickly—and more cost-effectively—bring its innovations into the hospital. | The Mayo Clinic Platform's Solutions Studio program will work with digital health companies "from idea to integration into clinical workflows." The system pitches it as a cost-effective way for innovators to bring their offerings to the point of care.

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STAT+: Small studies offer hope CAR-T can fight an aggressive brain cancer

STAT

A series of new studies are raising hopes that CAR-T , a process in which treatments are made by genetically editing a patient’s own white blood cells, can eventually be used to treat an incurable and deadly type of brain cancer, called glioblastoma multiforme, or GBM. In the most dramatic result, from a three-person study conducted by researchers at Massachusetts General Hospital, a 72-year-old man saw his tumor shrink 18.5% in just two days and then decrease further over the next two mo

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