Sat.Oct 28, 2023 - Fri.Nov 03, 2023

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Watch DSN: iA talks about what’s new in central fill and transforming life for pharmacists

Drug Store News

At NACDS’ Total Store Expo, DSN caught up with iA’s Tom Utech and Bobbi Jamriska about what’s new with the pharmacy automation solutions company.

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What’s next for COVID dark horse Novavax?

PharmaVoice

Novavax scored a new COVID vaccine go-ahead for the 2023-24 season, but is it the boost the company needs?

Vaccines 111
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Trending Sources

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Obesity Stigma Creates Nationwide Disparities by Keeps Patients From Seeking Care

Drug Topics

Providers create a disparity themselves by choosing not to treat obesity because stigma has led them to believe that patients with obesity are not sick enough to warrant medical intervention.

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Hyperkalemia Recurrence in Patients With CKD Contributes to Increased Health Care Resource Utilization, Cost

Pharmacy Times

The increased costs for patients with recurrent hyperkalemia were driven by the increased inpatient medical cost of additional time spent in the hospital following recurrence.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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CVS Health beats the Street with $2.3B in Q3 profit

Fierce Healthcare

CVS Health beat the Street on both earnings and revenue in the third quarter, reporting $2.3 billion in profit. | By comparison, the company reported a $3.4 billion loss in the third quarter of 2022 as it paid out its part in a global settlement over the opioid crisis.

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Infant mortality in the U.S. rose last year for the first time in two decades, says CDC

STAT

The U.S. infant mortality rate rose 3% last year — the largest increase in two decades, according to the Centers for Disease Control and Prevention. White and Native American infants, infant boys and babies born at 37 weeks or earlier had significant death rate increases. The CDC’s report, published Wednesday, also noted larger increases for two of the leading causes of infant deaths — maternal complications and bacterial meningitis.

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More Trending

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Study Data Show That Time-Restricted Eating May Be Effective for Weight Loss in Patients With Type 2 Diabetes

Pharmacy Times

This “refreshing alternative” to calorie restriction does not include calorie counting, yet it is naturally associated with greater energy restriction compared to the latter.

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UPDATED: Pfizer plans to shutter New Jersey site, discloses layoffs amid $3.5B cost-cutting drive

Fierce Pharma

Editor's note: This story has been updated with a comment from Pfizer. An earlier version of the story stated that nearly 800 jobs would be affected. | After plunging COVID revenues prompted Pfizer to embark on a cost-cutting crusade, more details about the company's savings efforts are coming into focus.

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Latest data shows millions of eligible Americans have been disenrolled from Medicaid

STAT

More than 10 million people were disenrolled from Medicaid over the past six months, according to the latest data published by a KFF tracker. The tracker has collected data on Medicaid enrollment since the first states began redetermining eligibility in April, after the expiration of the federal requirement of continuous coverage during the Covid-19 public health emergency.

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HPV Vaccines Have Reshaped the Epidemiological Landscape

Drug Topics

Prophylactic HPV vaccines have demonstrated remarkable efficacy, exceeding 98%, and they are already proving to be effective in the prevention of anogenital warts, precancerous lesions, and cancer alike.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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Understanding the Continuum of Pharmacist Prescribing

Pharmacy Times

It is crucial to continue to evolve from dependent prescribing to an independent model, and address barriers with opportunities for change.

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Pfizer cuts 200 jobs at COVID drug, vaccine plant in Michigan amid $3.5B savings campaign

Fierce Pharma

Pfizer’s plunging COVID-19 product demand has spurred a companywide cost-cutting campaign, with nearly 200 jobs now on the chopping block in Michigan. | Pfizer is cutting roughly 200 positions at its Kalamazoo site following a review of demand for its COVID-19 vaccine and antiviral Comirnaty and Paxlovid.

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Second recipient of genetically modified pig heart dies, six weeks after surgery

STAT

Nearly six weeks after his surgery, the world’s second recipient of a genetically modified pig heart has died, the University of Maryland announced Tuesday. Lawrence Faucette, a 58-year-old resident of Frederick, Md., with terminal heart disease, died Monday. He had received the experimental xenotransplant on September 20 at the University of Maryland Medical Center in an eight-hour operation.

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Pfizer, BioNTech Release Positive Topline Data for Combination COVID-19/Flu Vaccine

Drug Topics

The combination vaccine produced robust immune responses from vaccine candidates in a phase 1/2 clinical trial.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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American Pharmacists Month: Focusing on Patient Care

Pharmacy Times

Ramesh Cheruvu, PharmD, pharmacist and pharmacy manager at Health Mart Family Pharmacy at McKesson, discussed his journey in the pharmaceutical industry and how it has changed since he became a pharmacist.

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As COVID sales crater, Pfizer takes $5.6B in inventory write-offs on Paxlovid, Comirnaty

Fierce Pharma

For Pfizer, several years of pandemic megaprofits have soured as overstocked COVID-19 drugs and vaccines take a major toll on the drug behemoth’s financials. | Pfizer's pandemic megaprofits have soured as overstocked COVID-19 drugs and vaccines take a major toll on the drug behemoth’s financials.

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Extreme heat could lead to 233% increase in U.S. excess cardiovascular deaths, study says

STAT

When the human body is exposed to extreme heat, it tries to fight back. To keep us from cooking, our hearts pump faster and harder to distribute the hot blood out to our fingers and toes, away from precious internal organs. We produce more sweat, and when it evaporates, the blood beneath the skin’s surface cools down, helping to lower our body temperature.

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Once a high-flying 'unicorn,' Olive AI sells two key businesses, winds down operations

Fierce Healthcare

Healthcare startup Olive saw a meteoric rise in 2020 and 2021, spurred by the digital health funding boom and the need for automation during the COVID-19 pandemic. | It marks the end of the line for healthcare automation startup Olive AI. The company sold its clearinghouse and patient access business units to Waystar and its prior authorization business unit to Humata Health.

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5 Key Sessions, Interviews at ASN 2023 Kidney Week Annual Meeting

Pharmacy Times

Pharmacy Times will be at the American Society for Nephrology’s (ASN) 2023 Kidney Week Annual Meeting in Philadelphia, Pennsylvania, from November 2 to 5.

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Moderna takes hefty $1.3B COVID write-off, scales back manufacturing as sales shrink

Fierce Pharma

The days of booming COVID-19 vaccine sales, which sent Moderna into the ranks of pharma's top companies, have | The company is focusing on scaling back its manufacturing efforts to cope with the lack of COVID-19 vaccine demand.

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Opinion: I lost my son to OxyContin. ‘The Fall of the House of Usher’ is my Sackler revenge fantasy

STAT

Editor’s note: This essay contains spoilers for the Netflix show “The Fall of the House of Usher.” “W atch “ The Fall of the House of Usher” on Netflix when you can. F**cking Great! Totally based on the Sacklers—Fictional obviously but so damn good!

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Amazon's Rx to fix the pharmacy experience as brick-and-mortar drugstores struggle

Fierce Healthcare

Leveraging its logistics and supply chain muscle, now including drone delivery, Amazon wants to make it faster and easier for patients to get their prescription medications and speed up "triage to | Amazon Pharmacy's focus on making it faster and more convenient for patients to get prescription medications comes as brick-and-mortar drugstores are limiting pharmacy hours and even closing locations across the country.

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Precision Medicine, Biomarkers, Advancements in Chronic Kidney Disease Treatment

Pharmacy Times

Coca notes the importance of precision medicine in CKD risk assessment and describes the potential impact multiple therapies can have on future CKD prediction and treatment in the future.

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After patent settlement, Amgen scores FDA nod for its biosimilar version of J&J's Stelara

Fierce Pharma

The FDA has signed off on Amgen’s biosimilar version of Johnson & Johnson’s autoimmune standout Stelara. | The FDA has approved Amgen’s biosimilar version of Johnson & Johnson’s autoimmune standout Stelara. But the new product will not launch until 2025 because of a settlement the companies made earlier this year, which delayed the launch in exchange for J&J dropping a patent infringement lawsuit.

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New antibiotic targets gonorrhea as well as last existing treatment, study shows

STAT

An important Phase 3 trial has shown that a new drug that targets gonorrhea works as well as the last existing antibiotic to treat the sexually transmitted infection, results that could lead to licensure of the first new treatment for gonorrhea in decades. The co-developers of the drug, the nonprofit Global Antibiotic Research & Development Partnership, or GARDP, and Innoviva Specialty Therapeutics, a subsidiary of Innoviva Inc., released topline results of the clinical trial on Wednesday.

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How behavioral health tech can help overcome adoption hurdles among neurodiverse populations

Fierce Healthcare

Technologies like wearables and virtual reality could become key tools in engaging neurodiverse patient populations, streamlining provider workflows and tracking outcomes, payers, therapists and te | Speakers at a virtual roundtable commended technologies like wearables and virtual reality (VR) for their potential to engage neurodiverse patients, streamline provider workflows, and measure and improve outcomes.

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Pharmacists Assist with Family Planning in Warfarin Patients

Pharmacy Times

In most patients who are pregnant or may become pregnant, warfarin is contraindicated due to increased risk of adverse fetal outcomes.

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Battling new rivals and bracing for Jakafi's patent cliff, Incyte shores up growth plan

Fierce Pharma

As several new JAK inhibitors threaten Incyte’s bread-and-butter Jakafi in myelofibrosis, the company is busy advancing new regimens ahead of the drug’s 2028 patent cliff. | As several new JAK inhibitors threaten Incyte’s bread-and-butter Jakafi in myelofibrosis, the company is busy advancing new regimens ahead of the drug’s 2028 patent cliff.

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American Cancer Society expands lung cancer screening guidelines for cigarette smokers

STAT

Most lung cancer screening guidelines hinge on how much people smoked tobacco and when they last smoked, but the American Cancer Society now says it doesn’t matter how long ago they quit. On Wednesday, the ACS released guidance recommending that anyone with a significant smoking history get an annual low-dose CT scan for lung cancer. The new guidelines also expand the age range for lung cancer screening to 50 through 80, instead of 55 through 74, and lower the smoking history requirement

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HHS proposes info blocking 'disincentives' for hospitals, clinician groups, ACOs

Fierce Healthcare

The Department of Health and Human Services (HHS) has released its plan to keep healthcare providers in line with data blocking requirements. | Providers determined to have committed information blocking would face changes to their status in certain Medicare programs, and subsequently a hit to program payments. Enforcement would begin once the proposed rule is finalized.

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Inflation Reduction Act Could Cause Delay in New Oncology Treatments Under Medicare Negotiations

Pharmacy Times

In an article by The New England Journal of Medicine, the authors discuss how drug companies could delay the approval of new oncology drugs under the IRA, delaying patient care.

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Eli Lilly, Redwire head to space to explore next frontier of drug development

Fierce Pharma

After Bristol Myers Squibb’s space odyssey earlier this year, another pharmaceutical major is pushing drug development to the fringes of Earth’s gravitational pull. | Eli Lilly is entering the orbit of Redwire Corporation to test the latter company's in-space drug manufacturing platform. The technology will be sent to the International Space Station aboard a SpaceX mission set to launch sometime after Nov. 5.

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STAT+: Tracking the FDA advisory panel on the first CRISPR-based treatment for sickle cell disease

STAT

The Food and Drug Administration is convening a meeting of outside experts on Tuesday to review exa-cel, a CRISPR-based treatment for sickle cell disease made by Vertex Pharmaceuticals and CRISPR Therapeutics. Tuesday’s meeting is set up a bit differently than most FDA advisory panels. The agency has not raised any concerns about exa-cel’s efficacy or safety, and there will not be a typical vote at the end of the day on whether the data from exa-cel’s pivotal clinical trial

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Cleveland Clinic to launch prescription delivery via drone in 2025, starting with specialty and rush medications

Fierce Healthcare

Cleveland Clinic plans to launch a drone delivery service to bring certain medications directly to patients’ homes, starting in 2025. | Cleveland Clinic plans to launch a drone delivery service to bring certain medications directly to patients’ homes, starting in 2025.

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