Sat.Feb 03, 2024 - Fri.Feb 09, 2024

article thumbnail

A scholar of the patient ‘revolution’ tracks the arc from powerlessness to influence

STAT

At the end of each chapter in “Rebel Health: A Field Guide to the Patient-Led Revolution in Medical Care,” there’s a box. It summarizes the chapter, distilling what a reader just encountered into easy-to-digest bullet points. The author, Susannah Fox, admits she stole that idea from “The Long Covid Survival Guide,” which was written by patients for patients.

137
137
article thumbnail

STAT+: AI can speed up drug discovery but don’t expect it to cure cancer, yet

STAT

David Reese calls it a “hinge moment” — the turning point when biotech and big tech merge to attack human disease with artificial intelligence. At Amgen, where he’s led drug research and development since 2018, Reese said this moment has finally arrived. The proof lies not only in organizational changes, such as his recent appointment as the company’s first chief technology officer, but also in Amgen’s broader push to embed AI into every aspect of the dr

144
144
Insiders

Sign Up for our Newsletter

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Trending Sources

article thumbnail

Consumers opting for deals over store loyalty amid inflation

Drug Store News

Three-in-four consumers still feel concerned about rising prices, even as inflation moderates, according to Deloitte’s 2024 U.S. Retail Industry Outlook.

98
article thumbnail

CGM Can Help Pregnant Patients With T1D Improve TIR, Outcomes

Drug Topics

Despite previously suggested benchmarks, investigators found that spending less time-in-range (TIR) can still improve maternal and perinatal outcomes among pregnant patients with type 1 diabetes (T1D).

201
201
article thumbnail

Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

article thumbnail

Black Women Experiencing Racism in 3 Categories Have Increased Risk of Coronary Heart Disease

Pharmacy Times

The investigators found that perceived racism in everyday life was not associated with a higher risk of coronary heart disease—only racism in the 3 specific categories.

149
149
article thumbnail

Opinion: Moving from crisis response to crisis prevention in U.S. mental health systems

STAT

Despite widespread promises of reform after the murder of George Floyd in 2020, in 2023, police killed at least 1,246 people — the most in more than a decade. This police violence is intertwined with a parallel public policy disaster: America’s abysmal mental health systems that force police officers to function as de facto mental health workers.

145
145

More Trending

article thumbnail

Diabetes Can Serve as Traumatic Stressor for Adolescents, Young Adults

Drug Topics

A new study found that over a quarter of participants with type 1 daiebets exhibited clinically relevant levels of posttraumatic stress symptoms related to a diabetes event that they experienced.

201
201
article thumbnail

Safety Analysis Shows PPSV23 Is Not Associated With Higher Risk of Serious Outcomes

Pharmacy Times

The 23-valent pneumococcal polysaccharide vaccine was most likely associated with a higher risk of immunological events for those who were immunocompromised, but the events were low.

Vaccines 139
article thumbnail

Studies cited in abortion pill case are retracted due to flaws and conflicts of interest

STAT

A medical journal has retracted two studies claiming to show the harms of the abortion pill mifepristone, citing conflicts of interest by the authors and flaws in their research. Two of the three studies retracted by medical publisher Sage Perspectives were cited in a  pivotal Texas court ruling  that has threatened access to the pill. The  U.S.

144
144
article thumbnail

Centene boosts guidance amid 'stronger than expected' marketplace enrollment

Fierce Healthcare

Centene posted $45 million in profit for the fourth quarter of 2023, with its profitability for the full year growing notably compared to 2022. | Centene posted $45 million in profit for the fourth quarter of 2023, with its profitability for the full year growing notably compared to 2022.

133
133
article thumbnail

What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

article thumbnail

COVID-19 Vaccination Rates Significantly Lower in Patients With Sickle Cell Disease

Drug Topics

Patients with SCD are more vulnerable to hospitalization due, in part, to SCD’s impact on the spleen, which filters infections in the blood and is a crucial organ for the immune system.

article thumbnail

Study Results Highlight Importance of Overcoming Stigma When Addressing Brain Health

Pharmacy Times

The study authors note that to effectively implement tools, processes, and strategies within practices, the stigma surrounding cognitive impairment must be addressed.

144
144
article thumbnail

Opinion: Aduhelm was a mess — and it could happen again

STAT

Last week, Biogen announced it will cease both the study and sale of Aduhelm, its FDA-approved monoclonal antibody for the treatment of Alzheimer’s disease. Its decision, the company explained, is not a response to new data about the drug’s safety or efficacy, but instead “a reprioritization of resources.” Simply put, it wasn’t about science or medicine.

FDA 145
article thumbnail

Senators working on legislation to reform how Medicare pays physicians

Fierce Healthcare

A bipartisan group of senators announced Friday that they are working on new legislation for “long-term reforms” to physician payments under Medicare and other program changes. | The lawmakers plan to investigate and pass "long-term reforms" that will "ensure financial stability for providers," among other goals. They plan to seek stakeholder input "in the coming weeks.

129
129
article thumbnail

5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

article thumbnail

AstraZeneca brings its cell therapy ambitions to Maryland with $300M plant investment, 150 planned hires

Fierce Pharma

Following a slew of cell therapy biotech team-ups, AstraZeneca is taking manufacturing into its own hands. | AstraZeneca is plugging $300 million into a new facility in Rockville, Maryland, to launch its cell therapy platforms in the United States for cancer trials and future commercial supply. In turn, AZ will create more than 150 new jobs.

129
129
article thumbnail

Cardiovascular Mortality Rates Increased From 2020 to 2022, Correlating With Pandemic

Pharmacy Times

Investigators also found that the mortality rates for cardiovascular disease from 2020 to 2022 reversed the improvements of reduced mortalities in the preceding decades.

139
139
article thumbnail

STAT+: Government warns Medicare Advantage insurers not to deny care based on AI

STAT

In recent months, the federal government has repeatedly told Medicare Advantage insurers that they cannot use artificial intelligence or algorithms to deny medical services the government routinely covers. But in finalizing a rule to that effect, it also stepped into a thicket of questions from insurers about a technology that is especially difficult to pin down: What is AI?

Insurance 144
article thumbnail

Data science in healthcare

pharmaphorum

Data science in healthcare is transforming the industry, from drug discovery to patient care. Learn about the role of data, artificial intelligence (AI), and the impact of initiatives like the NHS Datastore in revolutionising healthcare outcomes.

article thumbnail

AstraZeneca hit CEO Pascal Soriot's $45B revenue goal after all. But is Enhertu approaching a plateau?

Fierce Pharma

With $45.8 billion in 2023 revenues, AstraZeneca has met the $45 billion-by-2023 goal CEO Pascal Soriot established in 2014 when he was fending off a takeover bid from Pfizer. | AstraZeneca has met the $45 billion-by-2023 revenue goal that CEO Pascal Soriot established in 2014. But questions have emerged for one of the company's key growth drivers.

127
127
article thumbnail

Let’s Not Forget the Silent Killer: Hypertension

Pharmacy Times

The prevalence of hypertension continues to increase amongst adults in the United States, leading to other cardiovascular conditions. Lifestyle changes and medication adherence are essential for appropriate hypertension management.

132
132
article thumbnail

‘Where you live shouldn’t determine how you get cancer’: An oncologist on global disparities

STAT

The prediction is dire: Cancer cases around the world are expected to surge 77% by 2050, a new report from the World Health Organization estimates. That attention-grabbing statistic, based on an analysis of 185 countries, cites a growing, aging population and factors including tobacco, alcohol, obesity, and pollution. Perhaps the most damning part of the report reveals the disparities determined by income.

145
145
article thumbnail

Amazon cuts hundreds of jobs in One Medical, Pharmacy units

Fierce Healthcare

Amazon is eliminating a "few hundred roles" across One Medical and Amazon Pharmacy, the company confirmed Tuesday. | Amazon is eliminating a "few hundred roles" across One Medical and Amazon Pharmacy, the company confirmed Tuesday.

126
126
article thumbnail

As cancer drug shortages persist, ASCO official urges congressional action at hearing

Fierce Pharma

A year into a dire shortage of essential cancer medicines in the U.S., the American Society of Clinical Oncologists (ASCO) is again pushing Congress to act to end the crisis. | The oncology drug supply crisis has entered its second year, and doctors still face "impossible choices" without access to standard-of-care therapies, ASCO's chief medical officer, Dr.

124
124
article thumbnail

Biosimilar Adalimumab, Etanercept Have Equivalent Effectiveness to Reference Drugs Over 48 Months

Pharmacy Times

The levels of disease activity after 6 months of tumor necrosis factor-α inhibitors could help predict the response to therapy at 4 years for those who have long-standing rheumatoid arthritis.

132
132
article thumbnail

STAT+: More than half the slots on a key vaccine advisory panel are vacant. Where’s HHS?

STAT

A critical government advisory committee charged with charting U.S. vaccination policy appears to be atrophying, jeopardizing timely decision-making on how vaccines should be used in this country. The Advisory Committee on Immunization Practices, which has in recent years been a 15-person panel, has eight vacancies — one of which dates back more than a year.

Vaccines 143
article thumbnail

How payers can help fix broken mental healthcare system

Fierce Healthcare

The mental healthcare system in the U.S. | Commercial health plans might do a better job of making community-based healthcare that relies on laypeople a reality than the pilots launched by government officials, one expert says.

123
123
article thumbnail

Novo Nordisk settles with 2 Florida sellers of compounded Ozempic

Fierce Pharma

Novo Nordisk has reached confidential settlements with two Florida sellers of compounded versions of the mega-blockbuster semaglutide treatments Ozempic and Wegovy, the company said on Friday. | Novo Nordisk has reached confidential settlements with two Florida sellers of compounded versions of the mega-blockbuster semaglutide treatments Ozempic and Wegovy, the company said on Friday.

article thumbnail

Negative Childhood Experiences Could Impact Cardiovascular Health in Adulthood

Pharmacy Times

In a study, more than 28% of participants met an ideal cardiovascular health score at the beginning of the study, with only 16% having ideal cardiovascular health at the 20-year mark.

131
131
article thumbnail

Wegovy is usually taken indefinitely. Amgen wants a version that can be tapered down

STAT

Amgen is trying a unique strategy with its obesity drug candidate: testing whether it can wean patients toward lower or less frequent doses over time. Very early data hints that Amgen’s candidate, called MariTide, may provide longer-lasting weight loss than highly popular obesity drugs on the market like Novo Nordisk’s Wegovy and Eli Lilly’s Zepbound.

144
144
article thumbnail

Banking on telehealth to reach rural patients, University of Rochester Medical Center rolls out innovative virtual care pilot

Fierce Healthcare

Banking on telehealth to reach rural patients, University of Rochester Medical Center rolls out innovative virtual care pilot hlandi Fri, 02/09/2024 - 14:36

131
131
article thumbnail

Eli Lilly mounts clinical and commercial case for tirzepatide as Mounjaro, Zepbound chalk up major gains

Fierce Pharma

Locked in a heated battled with Novo Nordisk’s semaglutide franchise, Eli Lilly’s tirzepatide is beginning to come into its own—both with regards to sales and amid attempts to show the dual GIP/GLP | Locked in a heated battled with Novo Nordisk’s semaglutide franchise, Eli Lilly’s tirzepatide is beginning to come into its own—both with regards to sales and amid attempts to show the dual GIP/GLP-1 agonist can strike out beyond diabetes and obesity.

121
121
article thumbnail

FDA Grants Breakthrough Therapy Designation to Nipocalimab for the Treatment of Rare Disease in Pregnancy

Pharmacy Times

In a study, nipocalimab helped more than 50% of patients with high-risk of hemolytic disease of the fetus and newborn achieve a safe live birth.

FDA 139
article thumbnail

Higher naloxone doses have no impact on overdose survival, study shows

STAT

People receiving a double dose of naloxone are no more likely to survive an opioid overdose than people receiving a standard, 4-milligram nasal spray, according to a new study. The new paper , published Thursday in the Centers for Disease Control and Prevention’s Morbidity and Mortality Weekly Report, showed no significant difference in survival rates between people who were revived using 4- and 8-milligram sprays of naloxone, commonly known by the brand name Narcan.

143
143
article thumbnail

Virgin Pulse, HealthComp unveil rebrand as employer health company eyes accelerated growth

Fierce Healthcare

Three months following the merger of Virgin Pulse and benefits administrator HealthComp, the combined company has rebranded as Personify Health with its sights set on revamping the patient experien | Personify Health introduced what it calls a personalized health platform that combines HealthComp's health plan administration capabilities with Virgin Pulse's holistic wellbeing solutions and comprehensive health navigation.

121
121