Sat.Nov 11, 2023 - Fri.Nov 17, 2023

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How Your Pharmacy Can Celebrate Thanksgiving this Cold and Flu Season

PioneerRx

The most wonderful time of the year is slowly approaching. Temperatures are falling, days are getting shorter (thanks, daylight savings), and holiday lights are.

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Women With Endometriosis More Likely to Experience Mental Health, Menstrual, Pain Symptoms

Drug Topics

Women with endometriosis face an average of 7 to 11 years between the time of symptom onset and diagnosis, during which they experience increased symptoms, hospitalizations, and health care resource utilization.

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Vitamin D Supplementation During Pregnancy Reduced Rates of Asthma, Wheezing in Children

Pharmacy Times

Compared to the standard prenatal vitamin alone, vitamin D supplementation with the prenatal vitamin reduced the risk of asthma and wheezing in children by approximately 50%.

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Flu season is approaching, CDC says

STAT

Flu activity in many parts of the United States is starting to rise more rapidly, signaling that flu season is on the horizon, the Centers for Disease Control and Prevention reported Friday. With Americans set to travel for Thanksgiving gatherings next week, people who’ve been waiting to get a flu shot should think about acting now, Alicia Budd, the CDC’s team lead for domestic flu surveillance, told STAT.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Novo Nordisk fights back at Lilly with Wegovy combo trial against Zepbound in obesity

Fierce Pharma

In response to an onslaught from Eli Lilly, Novo Nordisk is escalating the obesity market battle with a new head-to-head trial against its archrival. | In response to an onslaught from Eli Lilly, Novo Nordisk is escalating the obesity market battle with a new head-to-head trial against its archrival.

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Study Identifies Ketogenic Diet as Ideal Choice for IVF Success in Patients with PCOS

Drug Topics

For patients with polycystic ovary syndrome, 75% of whom have irregular or no ovulation, following a ketogenic diet improved IVF outcomes and metabolic health.

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More Trending

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STAT+: Even as Wegovy rides high, interest surges in weight loss drugs that preserve muscle

STAT

Have you ever seen a mouse with a set of muscles more appropriate for a bodybuilder or comic book superhero? Well, 25 years ago, researchers at Johns Hopkins University made it happen. By silencing a gene responsible for producing a protein called myostatin, they directed tiny mouse bodies to grow double the amount of lean muscle they would normally, leading to mice with bulky arms, defined pectorals, and an overall more substantial body mass.

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Primary care player Forward unveils AI-based, self-serve CarePods backed by $100M investment

Fierce Healthcare

Primary care player Forward unveiled this week what it has been quietly working on the past two years—self-serve CarePods that use artificial intelligence to screen and diagnose health conditions.< | Primary care player Forward unveiled this week what it has been quietly working on the past two years—self-serve CarePods that use artificial intelligence to screen and diagnose health conditions.

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US Vaccine Adverse Event Reporting System Not Meeting Standards

Drug Topics

VAERS was designed to collect reports of symptoms, diagnoses, hospital admissions, and deaths after vaccination for postmarket safety signals.

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Addressing Burnout: Understanding the Root Causes in the Workplace

Pharmacy Times

In this multi-part series on burnout and the problems currently facing pharmacy, trauma-informed pharmacist Helen Sairany, PharmD, MBA, discusses why burnout is skyrocketing.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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STAT+: U.K. approves world’s first CRISPR-based medicine, giving greenlight to therapy for sickle cell, thalassemia

STAT

LONDON — Regulators in the U.K. on Thursday approved a CRISPR-based medicine to treat both sickle cell disease and beta thalassemia, making it the world’s first therapy built on the revolutionary gene-editing technology and ushering in a new phase of genetic medicine.   The authorization of the therapy, from Vertex Pharmaceuticals and CRISPR Therapeutics, is itself not a surprise.

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UnitedHealthcare hit with class action over alleged use of AI to deny Medicare Advantage claims

Fierce Healthcare

UnitedHealthcare is facing a potential class action lawsuit following allegations that it used an algorithm to deny claims for post-acute care services in Medicare Advantage. | UnitedHealthcare is facing a potential class action lawsuit following allegations that it used an algorithm to deny claims for post-acute care services in Medicare Advantage.

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Pfizer's cost-cutting campaign hits Sandwich site in UK, where 500 workers will lose jobs

Fierce Pharma

Earlier this month, Pfizer’s $3.5 billion cost-cutting campaign crossed overseas to Ireland. Now, just a week later, Pfizer is announcing hundreds more job cuts in the U.K. | Pfizer plans to cut approximately 500 roles and ax its Pharmaceutical Sciences Small Molecule capabilities at its site in Sandwich in Kent in the U.K. The move is a consequence of Pfizer’s enterprisewide cost realignment program, which the drugmaker unveiled in mid-October.

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New Blood-Based Rapid Test Can Simultaneously Detect HIV, TB

Pharmacy Times

Not only is the test significant for identifying HIV and TB, but it can be safer for patients living with HIV due to their suppressed immune systems.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Report: Measles cases and deaths increase worldwide, as childhood vaccinations rates decline

STAT

A dangerous decline in the rate of children vaccinated against measles is spurring a global increase in cases and deaths from the highly contagious virus, according to a report released Thursday. Estimated measles cases rose 18% to 9 million in 2022 when compared to the previous year, and deaths rose by 43% to 136,200, according to the report , jointly authored by the World Health Organization and the Centers for Disease Control and Prevention.

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Prior authorization and other regulatory burdens have increased since last year, practices tell MGMA

Fierce Healthcare

Nine in 10 polled medical practices say their regulatory burden has increased over the past year with prior authorization, audits and appeals, the Medicare Quality Payment Program (QPP) and require | The latest annual poll of practices' regulatory burden outlined prior authorization, audits and appeals, Medicare QPP and other leading pain points that physicians say are weighing down theor staff and ability to deliver care.

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FDA signs off on new uses for Astellas and Pfizer's Xtandi, Merck's Keytruda

Fierce Pharma

The FDA has signed off on label expansions for two of the world’s most important cancer medicines—Merck’s Keytruda and Pfizer and Astellas’ Xtandi. | The FDA has signed off on label expansions for two of the world’s most important cancer medicines—Merck’s Keytruda and Pfizer and Astellas’ Xtandi. Keytruda’s expansion is in stomach cancer. Xtandi’s new indication expands its already deep portfolio in the treatment of prostate cancer.

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Disproportionate Burden of Cardiovascular-Kidney-Metabolic Factors in Patients with Adverse SDOH

Pharmacy Times

Session speaker Powell-Wiley explains how screening for SDOH in patients as cardiovascular-kidney-metabolic syndrome stages progress can help better understand their individual social needs.

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Key questions (and answers) about the historic approval of a CRISPR-based medicine

STAT

History just happened. For the first time, a regulator has cleared a treatment using CRISPR , the gene-editing technology, for patients. The regulator is the United Kingdom’s Medicines and Healthcare products Regulatory Agency. The product is Casgevy, a treatment for sickle cell disease and beta thalassemia, two blood disorders. It was developed by CRISPR Therapeutics, the Swiss company co-founded by Nobel laureate Emmanuelle Charpentier, and Vertex Pharmaceuticals, a large Boston-based b

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Express Scripts embraces cost-plus pricing with new ClearNetwork model

Fierce Healthcare

The country's largest pharmacy benefit manager is taking a page out of Mark Cuban's book. | The country's largest pharmacy benefit manager is taking a page out of Mark Cuban's book.

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Bristol Myers' $4.1B Turning Point buy yields FDA approval for lung cancer drug Augtyro

Fierce Pharma

Watch out, Pfizer and Roche. Thanks to an acquisition and now an FDA approval, Bristol Myers Squibb is entering a niche lung cancer market. | Watch out, Pfizer and Roche. Thanks to an acquisition and now an FDA approval, Bristol Myers Squibb is entering a niche lung cancer market.

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Cardiovascular-Kidney-Metabolic Syndrome Requires a Collaborative Approach to Treatment

Pharmacy Times

The American Heart Association published a statement describing the cardiovascular-kidney-metabolic (CKM) construct, specifically highlighting treatment challenges for CKM syndrome.

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How the Bad River Tribe flipped the script on the Native American opioid crisis

STAT

BAD RIVER RESERVATION, Wis. — Sunlight is streaming through holes in the walls of a disused, corrugated metal shack, revealing its modest insides: Dirt floors, stacks of two-by-fours, and a pile of Little Caesars pizza boxes under attack by a work crew on lunch break. This building is clearly not ready to be a home. But in the next 24 hours, it must become one.

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US patients believe generative AI can improve healthcare access, affordability, survey finds

Fierce Healthcare

As the industry continues to debate the promise and risks of artificial intelligence in healthcare, patients are bullish on the potential for generative AI to improve access and even lower healthca | As the industry continues to debate the promise and risks of artificial intelligence in healthcare, patients are bullish on the potential for generative AI to improve access and even lower healthcare costs.

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Pharma is racing to oncology's first line, causing a rethink of early-stage disease treatment

Fierce Pharma

Timothy Yap, Ph.D., used to see patients nearing the end of their cancer journey in his phase 1 department at the University of Texas' MD Anderson Cancer Center. | Cancer drugs are getting better thanks to innovation, driven by the data and regulatory forces like Project FrontRunner.

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Expert Discusses Investigational AVB-101 for Frontotemporal Dementia

Pharmacy Times

Lisa Deschamps, CEO of AviadoBio, discusses frontotemporal dementia and AVB-101, a one-time therapy designed to stop disease progression by delivering a functional copy of the GRN gene and restoring progranulin levels in the brain.

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FDA grants approval for first time to a home test for chlamydia and gonorrhea

STAT

The Food and Drug Administration granted marketing approval to a home test for chlamydia and gonorrhea on Wednesday, the first such authorization of a home test to detect the two most common sexually transmitted infections in this country. The marketing approval was granted to LetsGetChecked’s Simple 2 Test, which allows individuals to collect a sample at home that is then submitted to a laboratory for processing.

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New York State proposes new cybersecurity regulations for hospitals

Fierce Healthcare

New York has proposed a slew of new cybersecurity regulations for the state’s hospitals and plans to funnel $500 million from its FY24 budget to help facilities upgrade their technology systems, Go | Should its proposal be finalized, the Empire State will give hospitals a year and access to a $500 million fund to bring their facilities into compliance.

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AstraZeneca plans to exit 'beating heart' of Indian operations in Bangalore

Fierce Pharma

Amid a corporate review of AstraZeneca’s global manufacturing and supply network, the company’s Indian subsidiary is planning to close up shop at the “beating heart” of its India operations in Bang | AstraZeneca Pharma India will exit its production plant in Bangalore, India, “in due course,” the company said in a filing. AZ plans to find a buyer who can also serve as a contract manufacturer for the drugs produced there.

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Data Show Benefit of Intensive Blood Pressure Reduction Is Consistent in East Asian Population With Hypertension, High Cardiovascular Risk

Pharmacy Times

The SPRINT trial was the first to demonstrate the benefit of further reduction in blood pressure, but it included a limited Asian population and excluded patients with diabetes or history of stroke.

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STAT+: UnitedHealth faces class action lawsuit over algorithmic care denials in Medicare Advantage plans

STAT

A class action lawsuit was filed Tuesday against UnitedHealth Group and a subsidiary alleging that they are illegally using an algorithm to deny rehabilitation care to seriously ill patients, even though the companies know the algorithm has a high error rate. The class action suit, filed on behalf of deceased patients who had a UnitedHealthcare Medicare Advantage plan and their families by the California-based Clarkson Law Firm, follows the publication of a STAT investigation Tuesday.

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Civil rights groups deal failing grades to states on Medicaid disenrollments

Fierce Healthcare

A coalition including the NAACP and other civil rights organizations released a scorecard Thursday grading each state on its policies handling the Medicaid unwinding period. | Just one state received a passing score on Medicaid redeterminations from a coalition of nationally recognized civil rights groups.

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2seventy suffers sales slump on high production charges for BMS-partnered CAR-T med Abecma

Fierce Pharma

If you’re curious about the pitfalls of CAR-T drug commercialization, look no further than Bristol Myers Squibb’s Abecma partner 2seventy bio. | After reporting a sizable revenue decline for its BMS-parntered multiple myeloma cell therapy in 2023’s third quarter, 2seventy stands out as a prime example of the dangers of scaling up a process before suffering lower-than-expected demand, one group of analysts contends.

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FDA Approves Liquid Form of Antibiotic for The Treatment of Infection

Pharmacy Times

The approval will benefit patients who have difficulty swallowing, dysphagia, or high taste sensitivities and struggle to adhere to the original antibiotic.

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